Research Topics
| J G HatlebakkSummaryAffiliation: Haukeland University Hospital Country: Norway Publications
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Detail Information
Publications
Review article: gastric acidity--comparison of esomeprazole with other proton pump inhibitorsJ G Hatlebakk
Department of Medicine, Haukeland Sykehus, University of Bergen, N 5021 Bergen, Norway
Aliment Pharmacol Ther 17:10-5; discussion 16-7. 2003..The improved acid control with esomeprazole compared with other proton pump inhibitors is likely to result in superior healing rates and improved symptom relief, with fewer therapy-resistant patients...
Nocturnal gastric acidity and acid breakthrough on different regimens of omeprazole 40 mg dailyJ G Hatlebakk
Department of Medicine, Allegheny University Hospitals Graduate, Philadelphia, Pennsylvania 19146, USA
Aliment Pharmacol Ther 12:1235-40. 1998..0 lasting for longer than 1 h. Gastro-oesophageal reflux during NAB may be particularly injurious to the oesophageal mucosa, contributing to the chronic lesions complicating the condition...
Medical therapy. Management of the refractory patientJ G Hatlebakk
Department of Medicine, Haukeland Sykehus, University of Bergen, Norway
Gastroenterol Clin North Am 28:847-60. 1999..If followed, only a small group of patients should be medically refractory...
Gastric acidity and acid breakthrough with twice-daily omeprazole or lansoprazoleP O Katz
Oesophageal Research Laboratory, Department of Medicine, The Graduate Hospital, Phiadelphia, Pennsylvania 19146, USA
Aliment Pharmacol Ther 14:709-14. 2000..Nocturnal acid breakthrough, defined as gastric pH < 4.0 continuously for > 60 min, may compromise treatment goals in patients with GERD...
Stability of gastric secretory inhibition during 6-month treatment with omeprazole in patients with gastroesophageal reflux diseaseS Tefera
Division of Gastroenterology, Institute of Medicine, Haukeland Hospital, University of Bergen, Norway
Am J Gastroenterol 96:969-74. 2001..There is no evidence of diminution in the effects of 20 mg of omeprazole over time that could indicate the development of tolerance...
The effect of Helicobacter pylori eradication on gastro-oesophageal refluxS Tefera
Division of Gastroenterology, Department of Medicine, Haukeland Hospital, University of Bergen, Norway
Aliment Pharmacol Ther 13:915-20. 1999..Increased prevalence of oesophagitis has been reported following eradication of Helicobacter pylori. We hypothesized that H. pylori eradication might increase gastro-oesophageal acid reflux in patients with reflux oesophagitis...
Low densities of serotonin and peptide YY cells in the colon of patients with irritable bowel syndromeM el-Salhy
Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Box 4000, 54 09 Stord, Norway
Dig Dis Sci 57:873-8. 2012..Disturbances in gastrointestinal motility have been reported in patients with irritable bowel syndrome (IBS). Reduced endocrine cell density, as revealed by chromogranin A, has been reported in the colon of IBS patients...
Sensation evoked by esophageal distension in functional chest pain patients depends on mechanical stress rather than on ischemiaD A L Hoff
Institute of Medicine, University of Bergen, Bergen, Norway
Neurogastroenterol Motil 22:1170-6, e309-11. 2010..Functional chest pain is commonly reproduced by bag distension in the esophageal body. It is unknown whether such pain is primarily associated with mechanical stress and strain (force-deformation) or with changes in mucosal perfusion...
Gastric accommodation studied by ultrasonography in patients with reflux esophagitisS Tefera
Department of Medicine, Haukeland Hospital, University of Bergen, Norway
Dig Dis Sci 46:618-25. 2001..Postprandial distension of the proximal stomach may be a pathogenetic factor in reflux esophagitis...
Intragastric maldistribution of a liquid meal in patients with reflux oesophagitis assessed by three dimensional ultrasonographyS Tefera
Division of Gastroenterology, Institute of Medicine, Haukeland Hospital, University of Bergen, Norway
Gut 50:153-8. 2002..Our aim was to study intragastric volume and distribution of a liquid meal in patients with reflux oesophagitis using three dimensional ultrasonography...
Endoscopic ultrasound: a new look at achalasia?J G Hatlebakk
Allegheny University Hospitals Graduate, Philadelphia, PA 19146, USA
Eur J Gastroenterol Hepatol 10:543-5. 1998..Available data suggest that high frequency (20 MHz) and 3-D EUS has a potential to reliably discriminate between achalasia patients and normal subjects, and thereby be of diagnostic value...
Validation of the GerdQ questionnaire for the diagnosis of gastro-oesophageal reflux diseaseC Jonasson
Institute of Medicine, University of Bergen, Norway
Aliment Pharmacol Ther 37:564-72. 2013..The symptom-based management of GERD in primary care may be further optimised with the use of a questionnaire...
Randomised clinical trial: a comparison between a GerdQ-based algorithm and an endoscopy-based approach for the diagnosis and initial treatment of GERDC Jonasson
University of Bergen, Institute of Medicine, Norway
Aliment Pharmacol Ther 35:1290-300. 2012..The diagnosis of gastro-oesophageal reflux disease (GERD) remains challenging. An algorithm, facilitated by a questionnaire, may provide a more structured and cost-effective care of patients...
Eradication of Helicobacter pylori does not increase acid reflux in patients with mild to moderate reflux oesophagitisS Tefera
Division of Gastroenterology, Institute of Medicine, Haukeland Hospital, University of Bergen, Norway
Scand J Gastroenterol 37:877-83. 2002..We hypothesized that H. pylori eradication increases gastro-oesophageal acid reflux in such patients with time...
The role of diet in the pathogenesis and management of irritable bowel syndrome (Review)M el-Salhy
Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
Int J Mol Med 29:723-31. 2012....
A multimodal laser Doppler and endosonographic distension device for studying mechanosensation and mucosal blood flow in the oesophagusD A L Hoff
Institute of Medicine, University of Bergen, Bergen, Norway
Neurogastroenterol Motil 18:243-8. 2006..We conclude that the principle of measurement is sound and that the device can provide a basis for further studies...
Continued (5-year) followup of a randomized clinical study comparing antireflux surgery and omeprazole in gastroesophageal reflux diseaseL Lundell
Department of Surgery, Sahlgrenska University Hospital, , Sweden
J Am Coll Surg 192:172-9; discussion 179-81. 2001..But if the dose of omeprazole was adjusted in case of relapse, the two therapeutic strategies reached levels of efficacy that were not statistically different...
Seven-year follow-up of a randomized clinical trial comparing proton-pump inhibition with surgical therapy for reflux oesophagitisL Lundell
Department of Surgery, Karolinska University Hospital, Stockholm, Sweden
Br J Surg 94:198-203. 2007..This randomized clinical trial compared long-term outcome after antireflux surgery with acid inhibition therapy in the treatment of chronic gastro-oesophageal reflux disease (GORD)...
Changes of gastric mucosal architecture during long-term omeprazole therapy: results of a randomized clinical trialL Lundell
Department of Surgery, Karolinska University Hospital, Huddinge, Sweden
Aliment Pharmacol Ther 23:639-47. 2006..The impact of long-term acid suppression on the gastric mucosa remains controversial...
One-week esomeprazole treatment: an effective confirmatory test in patients with suspected gastroesophageal reflux diseaseF Johnsson
Dept of Surgery, Lund University Hospital, Lund, Sweden
Scand J Gastroenterol 38:354-9. 2003..The proton-pump inhibitor (PPI) omeprazole has been used as such a diagnostic tool. Intragastric acid control with esomeprazole is more effective than other PPIs and has the potential to offer an advance in the diagnostic use of PPIs...
Symptom-relieving effect of esomeprazole 40 mg daily in patients with heartburnF Johnsson
Dept of Surgery, Lund University Hospital, Lund, Sweden
Scand J Gastroenterol 38:347-53. 2003..To assess symptom relief in patients with heartburn following treatment with esomeprazole 40 mg daily...
Patients with endoscopic gastritis and/or duodenitis improve markedly following eradication of Helicobacter pylori, although less so than patients with ulcersS Olafsson
Institute of Medicine, Division of Gastroenterology, Haukeland University Hospital, Bergen, Norway
Scand J Gastroenterol 37:1386-94. 2002....
