Research Topics
| E GerdtsSummaryCountry: Norway Publications
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Publications
Correlates of left atrial size in hypertensive patients with left ventricular hypertrophy: the Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) StudyEva Gerdts
Department of Heart Disease, Haukeland University Hospital, Bergen, Norway
Hypertension 39:739-43. 2002....
Impact of age on left ventricular hypertrophy regression during antihypertensive treatment with losartan or atenolol (the LIFE study)E Gerdts
Institute of Medicine, University of Bergen, Norway
J Hum Hypertens 18:417-22. 2004....
Correlates of pulse pressure reduction during antihypertensive treatment (losartan or atenolol) in hypertensive patients with electrocardiographic left ventricular hypertrophy (the LIFE study)Eva Gerdts
Haukeland University Hospital, Bergen, Norway
Am J Cardiol 89:399-402. 2002....
Impact of diastolic Doppler indices on exercise capacity in hypertensive patients with electrocardiographic left ventricular hypertrophy (a LIFE substudy)Eva Gerdts
Department of Heart Disease, Haukeland University Hospital, Bergen, Norway
J Hypertens 20:1223-9. 2002..To assess whether Doppler evidence of impaired early diastolic relaxation during exercise is associated with lesser exercise capacity in hypertensive patients...
Impact of diabetes on treatment-induced changes in left ventricular structure and function in hypertensive patients with left ventricular hypertrophy. The LIFE studyE Gerdts
Institute of Medicine, University of Bergen
Nutr Metab Cardiovasc Dis 19:306-12. 2009..Diabetes is associated with left ventricular hypertrophy (LVH) and impaired systolic function in hypertensive patients, but less is known about its impact on LVH regression and functional improvement during antihypertensive treatment...
Long-term central hemodynamic effects at rest and during exercise of losartan in essential hypertensionP Omvik
Institute of Internal Medicine, Department of Cardiology, Bergen, Norway
Am Heart J 140:624-30. 2000..Losartan reduces blood pressure in patients with essential hypertension, but the long-term central hemodynamic effects at rest and during exercise are not known...
Renal hemodynamic effects of captopril and doxazosin during slight physical activity in hypertensive patients with type-1 diabetes mellitusE Svarstad
Renal Research Group, Institute of Medicine, University of Bergen, Norway
Kidney Blood Press Res 24:64-70. 2001....
Gender differences in systolic left ventricular function in hypertensive patients with electrocardiographic left ventricular hypertrophy (the LIFE study)E Gerdts
Department of Heart Disease, Haukeland University Hospital, Bergen, Norway
Am J Cardiol 87:980-3; A4. 2001..33). Thus, female gender is an independent predictor of higher systolic LV function in hypertensive patients with electrocardiographic LV hypertrophy...
Similar central hemodynamics in salt-sensitive and salt-resistant hypertensive patientsP Omvik
Department of Cardiology, Haukeland Hospital, Bergen, Norway
Blood Press 8:233-41. 1999..It is concluded that there is no difference in central hemodynamics in salt-sensitive and salt-resistant hypertensive patients when they are on their habitual salt diet...
Impact of overweight and obesity on cardiac benefit of antihypertensive treatmentE Gerdts
Institute of Medicine, University of Bergen, N 5021, Bergen, Norway
Nutr Metab Cardiovasc Dis 23:122-9. 2013..Less is known about the impact of BMI on improvement in left ventricular (LV) structure and function during antihypertensive treatment...
Prevalence and covariates of electrocardiographic left ventricular hypertrophy in diabetic patients in TanzaniaJ J K Lutale
Institute of Medicine and Centre for International Health, University of Bergen, Bergen, Norway
Cardiovasc J Afr 19:8-14. 2008..Therefore, the aim was to assess the prevalence of ECG-LVH in diabetic patients in Dares Salaam, Tanzania, and its relation to other cardiovascular risk factors...
Factors influencing reduction in blood pressure and left ventricular mass in hypertensive type-1 diabetic patients using captopril or doxazosin for 6 monthsE Gerdts
Department of Heart Disease, Haukeland Hospital, Bergen, Norway
Am J Hypertens 11:1178-87. 1998....
Brain abscess caused by paradoxical embolization in Ebstein's anomalyM T Lønnebakken
Department of Heart Disease, Haukeland University Hospital, 5021 Bergen, Norway
Eur J Echocardiogr 9:105-6. 2008..Ebstein's anomaly can remain undiagnosed until adulthood if the right ventricle, in spite of the smaller size, is haemodynamically well functioning...
Change in pulse pressure/stroke index in response to sustained blood pressure reduction and its impact on left ventricular mass and geometry changes: the life studyVittorio Palmieri
Division of Cardiology, Department of Medicine, Weill Medical College of Cornell University, New York, NY, USA
Am J Hypertens 21:701-7. 2008..In cross-sectional data in hypertensive subjects, brachial pulse pressure (PP)/Doppler stroke index (SVi), (PP/SVi) correlates weakly but significantly with left ventricular (LV) mass and relative wall thickness (RWT)...
Association of hemoglobin delivery with left ventricular structure and function in hypertensive patients: Losartan Intervention for End Point Reduction in Hypertension StudyPuneet Narayan
Veterans Administration Medical Center, Washington, DC 20422, USA
Hypertension 47:868-73. 2006..Thus, in hypertensive LVH, higher oxygen delivery capacity is associated with higher LV mass and impaired early diastolic LV filling...
Impact of hypertension on left ventricular hypertrophy regression and exercise capacity in patients operated for aortic valve stenosisDana Cramariuc
Institute of Medicine, University of Bergen, Bergen, Norway
Scand Cardiovasc J 40:167-74. 2006..To assess the influence of concomitant hypertension on left ventricular hypertrophy regression and exercise capacity in patients operated for aortic stenosis...
Electrocardiographic strain pattern and left ventricular diastolic function in hypertensive patients with left ventricular hypertrophy: the LIFE studyVittorio Palmieri
Weill Medical College of Cornell University, New York, NY 10021, USA
J Hypertens 24:2079-84. 2006....
Exercise performance during losartan- or atenolol-based treatment in hypertensive patients with electrocardiographic left ventricular hypertrophy (a LIFE substudy)Eva Gerdts
Institute of Medicine, University of Bergen, Bergen, Norway
Blood Press 15:220-6. 2006..The results may be explained by persistent impairment of myocardial relaxation influencing exercise capacity...
Left atrial size and risk of major cardiovascular events during antihypertensive treatment: losartan intervention for endpoint reduction in hypertension trialEva Gerdts
Institute of Medicine, University of Bergen, Haukeland University Hospital, N 5021 Bergen, Norway
Hypertension 49:311-6. 2007....
Electrocardiographic characteristics and metabolic risk factors associated with inappropriately high left ventricular mass in patients with electrocardiographic left ventricular hypertrophy: the LIFE StudyVittorio Palmieri
Weill Medical College of Cornell University, New York, NY 10021, USA
J Hypertens 25:1079-85. 2007....
Reduced exercise capacity in genetic haemochromatosisEinar Skulstad Davidsen
Department of Heart Disease, Haukeland University Hospital, University of Bergen, Norway
Eur J Cardiovasc Prev Rehabil 14:470-5. 2007..Many patients with genetic haemochromatosis complain about fatigue and reduced physical capacity. Exercise capacity, however, has not been evaluated in larger series of haemochromatosis patients treated with repeated phlebotomy...
Electrocardiographic and echocardiographic detection of myocardial infarction in patients with left-ventricular hypertrophy. The LIFE StudySilvana Cicala
Division of Cardiology, Weill Medical College of Cornell University, New York, NewYork 10021, USA
Am J Hypertens 20:771-6. 2007..Thus, we compared the accuracy of 2D echocardiography with Minnesota-code ECG criteria in detecting incident MI, adjudicated during serial evaluation in patients with hypertension and LVH...
Gender differences in left ventricular structure and function during antihypertensive treatment: the Losartan Intervention for Endpoint Reduction in Hypertension StudyEva Gerdts
Institute of Medicine, University of Bergen, Haukeland University Hospital, N 5021 Bergen, Norway
Hypertension 51:1109-14. 2008..07; P<0.01). Hypertensive women in this study retained higher left ventricular ejection fraction and stress-corrected midwall shortening in spite of less hypertrophy regression during long-term antihypertensive treatment...
Left atrial systolic force in hypertensive patients with left ventricular hypertrophy: the LIFE studyMarcello Chinali
Weill Medical College of Cornell University, New York, NY 10021, USA
J Hypertens 26:1472-6. 2008....
Effects of losartan in women with hypertension and left ventricular hypertrophy: results from the Losartan Intervention for Endpoint Reduction in Hypertension StudyIngrid Os
Department of Nephrology, Ullevaal University Hospital, 0407 Oslo, Norway
Hypertension 51:1103-8. 2008....
Factors influencing left ventricular structure and stress-corrected systolic function in men and women with asymptomatic aortic valve stenosis (a SEAS Substudy)Dana Cramariuc
Institute of Medicine, University of Bergen, Bergen, Norway
Am J Cardiol 101:510-5. 2008..Women have higher stress-corrected indexes of systolic function independent of LV geometry or size, wall stress, older age, or more concomitant hypertension...
Gender differences in regression of electrocardiographic left ventricular hypertrophy during antihypertensive therapyPeter M Okin
Greenberg Division of Cardiology, Weill Cornell Medical College, New York, NY 10021, USA
Hypertension 52:100-6. 2008....
Clinical impact of 'in-treatment' wall motion abnormalities in hypertensive patients with left ventricular hypertrophy: the LIFE studySilvana Cicala
Division of Cardiology, Weill Cornell Medical College, New York, New York 10021, USA
J Hypertens 26:806-12. 2008..We examined whether 'in-treatment' wall motion abnormalities predicted outcome in the Losartan Intervention For Endpoint (LIFE) reduction in hypertension echocardiographic substudy...
Progressive hypertrophy regression with sustained pressure reduction in hypertension: the Losartan Intervention For Endpoint Reduction studyRichard B Devereux
Department of Medicine, Weill Medical College of Cornell University, New York, New York 10021, USA
J Hypertens 20:1445-50. 2002..To examine the time course of left ventricular (LV) geometric response to blood pressure (BP) control during 2 years of systematic antihypertensive treatment...
Impact of diabetes mellitus on regression of electrocardiographic left ventricular hypertrophy and the prediction of outcome during antihypertensive therapy: the Losartan Intervention For Endpoint (LIFE) Reduction in Hypertension StudyPeter M Okin
Division of Cardiology, Department of Medicine, Cornell University Medical Center, New York, NY 10021, USA
Circulation 113:1588-96. 2006....
Aortic valve sclerosis and albuminuria predict cardiovascular events independently in hypertension: a losartan intervention for endpoint-reduction in hypertension (LIFE) substudyMichael H Olsen
Department of Internal Medicine, Glostrup University Hospital, Glostrup, Denmark
Am J Hypertens 18:1430-6. 2005..We aimed to investigate whether they predicted cardiovascular (CV) events independently in patients with hypertension and electrocardiographic left ventricular (LV) hypertrophy...
Echocardiographic wall motion abnormalities in hypertensive patients with electrocardiographic left ventricular hypertrophy: the LIFE StudyVittorio Palmieri
Cornell Medical Center, New York, New York, USA
Hypertension 41:75-82. 2003..No significant differences were found between patients with global or segmental wall motion abnormalities...
Left ventricular mass regression in the LIFE study: effect of previous antihypertensive treatmentGerard P Aurigemma
Department of Medicine, Division of Cardiology, University of Massachusetts Medical School, Worcester, Massachusetts, USA
Am J Hypertens 16:180-6. 2003..Accordingly, our aim was to study the relationship between prior treatment and both baseline and 1-year echocardiographic LV mass in subjects enrolled in the Losartan Intervention For Endpoint reduction (LIFE) study...
Pulse pressure/stroke index and left ventricular geometry and function: the LIFE StudyVittorio Palmieri
Weill Medical College of Cornell University, New York, NY 10021, USA
J Hypertens 21:781-7. 2003..To evaluate the relationship between arterial stiffness estimated by the pulse pressure/stroke index ratio (PP/SVi) and prognostically relevant abnormalities of left ventricular geometry and function...
Change in systolic left ventricular performance after 3 years of antihypertensive treatment: the Losartan Intervention for Endpoint (LIFE) StudyKristian Wachtell
Copenhagen County University Hospital, Glostrup, Denmark
Circulation 106:227-32. 2002..We have shown that hypertensive patients with left ventricular (LV) hypertrophy have decreased LV midwall mechanics, but the effect of antihypertensive therapy remains unclear...
Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trialRichard B Devereux
Cornell Medical Center, 525 E 68th St, New York, NY 10021, USA
Circulation 110:1456-62. 2004..An echocardiographic substudy of the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial was designed to test the ability of losartan to reduce left ventricular (LV) mass more than atenolol...
Change in diastolic left ventricular filling after one year of antihypertensive treatment: The Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) StudyKristian Wachtell
Copenhagen County University Hospital, Glostrup, Denmark
Circulation 105:1071-6. 2002..It is well established that hypertensive patients with left ventricular (LV) hypertrophy have impaired diastolic filling. However, the impact of antihypertensive treatment and LV mass reduction on LV diastolic filling remains unclear...
Change of left ventricular geometric pattern after 1 year of antihypertensive treatment: the Losartan Intervention For Endpoint reduction in hypertension (LIFE) studyKristian Wachtell
Department of Medicine, Copenhagen County University Hospital, Glostrup, Denmark
Am Heart J 144:1057-64. 2002..Patients with hypertension have different types of left ventricular (LV) geometry, but the impact of blood pressure (BP) reduction on LV geometry change during antihypertensive treatment remains unclear...
Essential hypertension in womenIngrid Os
Department of Pharmacotherapeutics, University of Oslo, Oslo, Norway
Blood Press 13:272-8. 2004
Relation of left ventricular geometry and function to aortic root dilatation in patients with systemic hypertension and left ventricular hypertrophy (the LIFE study)Jonathan N Bella
Cornell Medical Center, New York, New York, USA
Am J Cardiol 89:337-41. 2002
Prognostic significance of left ventricular mass change during treatment of hypertensionRichard B Devereux
Department of Medicine, New York Presbyterian Hospital, Cornell Medical Center, New York, NY 10021, USA
JAMA 292:2350-6. 2004..Increased baseline left ventricular (LV) mass predicts cardiovascular (CV) complications of hypertension, but the relation between lower LV mass and outcome during treatment for hypertension is uncertain...
Aortic valve sclerosis relates to cardiovascular events in patients with hypertension (a LIFE substudy)Michael H Olsen
Department of Clinical Physiology and Nuclear Medicine, Glostrup University Hospital, DK 2600 Glostrup, Denmark
Am J Cardiol 95:132-6. 2005..AV sclerosis was associated with several CV risk factors and predicted CV events independently of prevalent CV disease and traditional CV risk factors, including LV mass and ejection fraction...
Left ventricular structure and function in sedentary and physically active subjects with left ventricular hypertrophy (the LIFE Study)Kurt Boman
Department of Medicine, Skellefteå County Hospital and Umeå University, 93186 Skellefteå, Sweden
Am J Cardiol 95:280-3. 2005..Patients with left ventricular hypertrophy had higher heart rates, left ventricular mass, and left atrial size independent of gender, blood pressure, or body mass index than physically active patients...
Cardiovascular morbidity and mortality in hypertensive patients with a history of atrial fibrillation: The Losartan Intervention For End Point Reduction in Hypertension (LIFE) studyKristian Wachtell
Department of Medicine, Glostrup University Hospital, Glostrup, Denmark
J Am Coll Cardiol 45:705-11. 2005..We assessed the impact of antihypertensive treatment in hypertensive patients with electrocardiographic (ECG) left ventricular (LV) hypertrophy and a history of atrial fibrillation (AF)...
Angiotensin II receptor blockade reduces new-onset atrial fibrillation and subsequent stroke compared to atenolol: the Losartan Intervention For End Point Reduction in Hypertension (LIFE) studyKristian Wachtell
Department of Medicine, Glostrup University Hospital, Glostrup, Denmark
J Am Coll Cardiol 45:712-9. 2005..This study was designed to evaluate whether different antihypertensive treatment regimens with similar blood pressure reduction have different effects on new-onset atrial fibrillation (AF)...
Urine albumin/creatinine ratio and echocardiographic left ventricular structure and function in hypertensive patients with electrocardiographic left ventricular hypertrophy: the LIFE study. Losartan Intervention for Endpoint ReductionKristian Wachtell
Laboratory of Cardiology, Department of Medicine, Copenhagen County University Hospital, Glostrup, Denmark
Am Heart J 143:319-26. 2002..However, the relationship between these markers of cardiovascular damage has not been evaluated in a large hypertensive population...
Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosisAnne B Rossebø
Division of Cardiology, Aker University Hospital, Trondheimsveien 235, N 0514 Oslo, Norway
N Engl J Med 359:1343-56. 2008..Hyperlipidemia has been suggested as a risk factor for stenosis of the aortic valve, but lipid-lowering studies have had conflicting results...
[Hypertension and heart disease]Eva Gerdts
Institutt for indremedisin, Universitetet i Bergen, 5020 Bergen
Tidsskr Nor Laegeforen 124:802-5. 2004..Heart failure symptoms may be subtle in hypertension, like tiredness or reduced physical capacity. Echocardiography can reveal subclinical heart disease as well as serve as a guide to correct diagnosis and treatment...
Blood pressure measurements by the Keito machine. Evaluation versus office blood pressure by physiciansEva M Staal
Department of Heart Disease; Institute of Medicine, Haukeland University Hospital, Bergen, Norway
Blood Press Monit 9:167-72. 2004..However, the difference can be much larger in individual patients. Therefore, the Keito machine cannot be recommended for medical screening of HT or as a replacement for follow-up by physicians...
Relation of impaired left ventricular filling to systolic midwall mechanics in hypertensive patients with normal left ventricular systolic chamber function: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) studyKristian Wachtell
Department of Medicine, Copenhagen County University Hospital, Glostrup, Denmark
Am Heart J 148:538-44. 2004..LV systolic midwall shortening (MWS) may be impaired in hypertensive patients with normal LV ejection fraction. However, it is unclear whether impaired LV filling is related to depressed systolic midwall mechanics...
Effect of losartan versus atenolol on aortic valve sclerosis (a LIFE substudy)Michael H Olsen
Glostrup University Hospital, Glostrup, Denmark
Am J Cardiol 94:1076-80. 2004....
Design and baseline characteristics of the simvastatin and ezetimibe in aortic stenosis (SEAS) studyAnne B Rossebø
Division of Cardiology, Aker University Hospital, Oslo, Norway
Am J Cardiol 99:970-3. 2007..4+/-0.7 mmol/L (126 mg/dl). The SEAS Study is the largest randomized trial to date in patients with AS and will allow determination of the prognostic value of aggressive lipid lowering in such patients...
Left atrial volume in patients with asymptomatic aortic valve stenosis (the Simvastatin and Ezetimibe in Aortic Stenosis study)Morten Dalsgaard
Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Am J Cardiol 101:1030-4. 2008..Furthermore, LA volume is related to AVA even when adjusting for other known risk factors for increased LA volume including of measurements of diastolic function...
