Magdy El-Salhy

Summary

Country: Norway

Publications

  1. doi request reprint Abnormal rectal endocrine cells in patients with irritable bowel syndrome
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Norway Section for Gastroenterology, Medicine, University of Bergen, Norway Electronic address
    Regul Pept 188:60-5. 2014
  2. doi request reprint The role of peptide YY in gastrointestinal diseases and disorders (review)
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Int J Mol Med 31:275-82. 2013
  3. doi request reprint Colonoscopy with mucosal biopsies in young rats: a model for experimental gastroenterology
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 7:1757-60. 2013
  4. pmc Changes in the symptom pattern and the densities of large-intestinal endocrine cells following Campylobacter infection in irritable bowel syndrome: a case report
    Magdy El-Salhy
    Department of Medicine, Section for Gastroenterology, Stord Helse Fonna Hospital, Stord, Norway
    BMC Res Notes 6:391. 2013
  5. doi request reprint Evaluation of the usefulness of colonoscopy with mucosal biopsies in the follow-up of TNBS-induced colitis in rats
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 8:446-50. 2013
  6. doi request reprint Serotonin and serotonin transporter in the rectum of patients with irritable bowel disease
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, 5416 Stord, Norway
    Mol Med Rep 8:451-5. 2013
  7. doi request reprint Reduced chromogranin A cell density in the ileum of patients with irritable bowel syndrome
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 7:1241-4. 2013
  8. doi request reprint Low-grade inflammation in the rectum of patients with sporadic irritable bowel syndrome
    Magdy El-Salhy
    Department of Medicine, Section for Gastroenterology, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 7:1081-5. 2013
  9. pmc Irritable bowel syndrome: diagnosis and pathogenesis
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, 5416 Stord, Norway
    World J Gastroenterol 18:5151-63. 2012
  10. pmc Chromogranin A cell density in the rectum of patients with irritable bowel syndrome
    M el-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 6:1223-5. 2012

Collaborators

Detail Information

Publications31

  1. doi request reprint Abnormal rectal endocrine cells in patients with irritable bowel syndrome
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Norway Section for Gastroenterology, Medicine, University of Bergen, Norway Electronic address
    Regul Pept 188:60-5. 2014
    ..The densities of PYY and somatostatin cells are potential biomarkers with good sensitivity and specificity for the diagnosis of IBS. ..
  2. doi request reprint The role of peptide YY in gastrointestinal diseases and disorders (review)
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Int J Mol Med 31:275-82. 2013
    ..Thus, in order to use PYY as a drug, receptor-specific agonists or antagonists need to be developed...
  3. doi request reprint Colonoscopy with mucosal biopsies in young rats: a model for experimental gastroenterology
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 7:1757-60. 2013
    ..Taking biopsies with the forceps at full jaw length and swing resulted in perforation, which may be avoided by obtaining biopsies with the outer tip of the biopsy forceps...
  4. pmc Changes in the symptom pattern and the densities of large-intestinal endocrine cells following Campylobacter infection in irritable bowel syndrome: a case report
    Magdy El-Salhy
    Department of Medicine, Section for Gastroenterology, Stord Helse Fonna Hospital, Stord, Norway
    BMC Res Notes 6:391. 2013
    ..A low-grade inflammation has been reported to occur in PI-IBS. Abnormalities in intestinal endocrine cells have been reported in both sporadic IBS and PI-IBS...
  5. doi request reprint Evaluation of the usefulness of colonoscopy with mucosal biopsies in the follow-up of TNBS-induced colitis in rats
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 8:446-50. 2013
    ..Although biopsy samples collected during colonoscopies may be used to assess the degree of inflammation, whole-wall samples are superior in this regard...
  6. doi request reprint Serotonin and serotonin transporter in the rectum of patients with irritable bowel disease
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, 5416 Stord, Norway
    Mol Med Rep 8:451-5. 2013
    ....
  7. doi request reprint Reduced chromogranin A cell density in the ileum of patients with irritable bowel syndrome
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 7:1241-4. 2013
    ..The present finding lends support to the suggestion that IBS is caused by a biological abnormality, and intestinal CgA cell density may be used as a biological marker for the diagnosis of IBS...
  8. doi request reprint Low-grade inflammation in the rectum of patients with sporadic irritable bowel syndrome
    Magdy El-Salhy
    Department of Medicine, Section for Gastroenterology, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 7:1081-5. 2013
    ..These findings oppose low‑grade inflammation as a pathogenic factor in sporadic IBS. Low‑grade inflammation may, however, play an important role in the pathogenesis of a subset of IBS, namely post‑infectious IBS (PI‑IBS)...
  9. pmc Irritable bowel syndrome: diagnosis and pathogenesis
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, 5416 Stord, Norway
    World J Gastroenterol 18:5151-63. 2012
    ..Patients with PI- and IBD-IBS exhibit low-grade mucosal inflammation, as well as abnormalities in the NES of the gut...
  10. pmc Chromogranin A cell density in the rectum of patients with irritable bowel syndrome
    M el-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 6:1223-5. 2012
    ..As CgA cell density represents the total endocrine cell content of the rectum, changes in specific endocrine cells in IBS patients cannot be excluded...
  11. pmc High densities of serotonin and peptide YY cells in the colon of patients with lymphocytic colitis
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Box 4000, 5409 Stord, Norway
    World J Gastroenterol 18:6070-5. 2012
    ..To investigate colonic endocrine cells in lymphocytic colitis (LC) patients...
  12. pmc Chromogranin A cell density as a diagnostic marker for lymphocytic colitis
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Box 4000, 54 09, Stord, Norway
    Dig Dis Sci 57:3154-9. 2012
    ..In a previous study on IBS, some patients showed extremely high colonic chromogranin A cell density. Further examination of these patients showed that they suffered from LC...
  13. ncbi request reprint Irritable bowel syndrome: the role of gut neuroendocrine peptides
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Norway
    Front Biosci (Elite Ed) 4:2783-800. 2012
    ..In particular, the cell density of duodenal chromogranin A expressing cells appears to be a good histopathological marker for the diagnosis of IBS with high sensitivity and specificity...
  14. doi request reprint The role of diet in the pathogenesis and management of irritable bowel syndrome (Review)
    M el-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Int J Mol Med 29:723-31. 2012
    ....
  15. pmc Low densities of serotonin and peptide YY cells in the colon of patients with irritable bowel syndrome
    M el-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Box 4000, 54 09 Stord, Norway
    Dig Dis Sci 57:873-8. 2012
    ..Disturbances in gastrointestinal motility have been reported in patients with irritable bowel syndrome (IBS). Reduced endocrine cell density, as revealed by chromogranin A, has been reported in the colon of IBS patients...
  16. ncbi request reprint Ghrelin in patients with irritable bowel syndrome
    M el-Salhy
    Section for Gastroenterology, Medicine Clinic, Stord Helse Fonna Hospital, 54 09 Stord, Norway
    Int J Mol Med 23:703-7. 2009
    ....
  17. doi request reprint Abnormal small-intestinal endocrine cells in patients with irritable bowel syndrome
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Box 4000, 54 09 Stord, Norway
    Dig Dis Sci 55:3508-13. 2010
    ..General disturbances in gastrointestinal motility have been reported in patients with irritable bowel syndrome (IBS). The gastrointestinal tract hormones play an important role in regulating gastrointestinal motility...
  18. doi request reprint High chromogranin A cell density in the colon of patients with lymphocytic colitis
    M el-Salhy
    Department of Medicine, Stord Helse Fonna Hospital, 54 09 Stord, Norway
    Mol Med Rep 4:603-5. 2011
    ..It is likely that the increase in colonic CgA in LC patients accounts for an increase in serotonin cells...
  19. doi request reprint Low density of ghrelin cells in the oxyntic mucosa correlated to slow gastric emptying in patients with type 1 diabetes
    Magdy El-Salhy
    Section for Gastroenterology, Medicine Clinic, Stord Helse Fonna Hospital, N 5409 Stord, Norway
    Mol Med Report 2:893-6. 2009
    ....
  20. doi request reprint The prevalence of celiac disease in patients with irritable bowel syndrome
    M el-Salhy
    Section for Gastroenterology, Medicine Clinic, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 4:403-5. 2011
    ..This amounts to a prevalence of 0.4% of CD in IBS patients. The present findings support the notion that IBS patients should be routinely examined for CD. This applies to all subtypes of IBS...
  21. doi request reprint Chromogranin A as a possible tool in the diagnosis of irritable bowel syndrome
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Scand J Gastroenterol 45:1435-9. 2010
    ..The aim of the present study was to establish a possible abnormality in CgA plasma level and in intestinal CgA cell density in IBS patients and to evaluate the outcome for the diagnosis of IBS...
  22. ncbi request reprint Ghrelin in gastrointestinal diseases and disorders: a possible role in the pathophysiology and clinical implications (review)
    Magdy El-Salhy
    Section for Gastroenterology, Institute of Internal Medicine, University of Bergen and Stord Helse Fonna Hospital, 5409 Stord, Norway
    Int J Mol Med 24:727-32. 2009
    ..Several studies have shown that ghrelin and its antagonist are a promising tool for treatment of several gastrointestinal diseases/disorders...
  23. doi request reprint Effects of dietary guidance on the symptoms, quality of life and habitual dietary intake of patients with irritable bowel syndrome
    Tarek Mazzawi
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 8:845-52. 2013
    ..Individual dietary guidance is a cost-effective option for the management of IBS...
  24. doi request reprint Is irritable bowel syndrome an organic disorder?
    Magdy El-Salhy
    Magdy El Salhy, Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, 5409 Stord, Norway
    World J Gastroenterol 20:384-400. 2014
    ..The changes in the gastrointestinal endocrine cells observed in IBS patients are highly consistent with the other abnormalities reported in IBS patients, such as visceral hypersensitivity, dysmotility, and abnormal secretion...
  25. doi request reprint Endocrine cells in the ileum of patients with irritable bowel syndrome
    Magdy El-Salhy
    Magdy El Salhy, Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, 54 09 Stord, Norway
    World J Gastroenterol 20:2383-91. 2014
    ..To study the ileal endocrine cell types in irritable bowel syndrome (IBS) patients...
  26. doi request reprint Amelioration of severe TNBS induced colitis by novel AP-1 and NF- κ B inhibitors in rats
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, P O Box 4000, 54 09 Stord, Norway Division of Gastroenterology, Department of Clinical Medicine, University of Bergen, P O Box 7800, 5020 Bergen, Norway
    ScientificWorldJournal 2014:813804. 2014
    ..03 and 0.01, resp.). It was concluded that DTCM-G and DHMEQ exhibit strong anti-inflammatory and anticancer activities with no apparent toxicity, which make them excellent drug candidates for clinical use in inflammatory bowel diseases...
  27. doi request reprint Irritable bowel syndrome: recent developments in diagnosis, pathophysiology, and treatment
    Magdy El-Salhy
    Department of Medicine, Section for Gastroenterology, Stord Hospital, Stord, Norway
    Expert Rev Gastroenterol Hepatol 8:435-43. 2014
    ..New and promising drugs for the treatment of IBS with constipation as the predominant symptom are currently on the market, and the treatment results have been satisfactory thus far. ..
  28. doi request reprint Chronic constipation and treatment options (Review)
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Hospital, Stord 5416, Norway
    Mol Med Rep 9:3-8. 2014
    ..This drug has also been found to be effective for the treatment of functional CC. In addition, biofeedback and sacral nerve stimulation are effective in the treatment of CC caused by pelvic floor disorders. ..
  29. doi request reprint Clinical presentation, diagnosis, pathogenesis and treatment options for lymphocytic colitis (Review)
    Magdy El-Salhy
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Int J Mol Med 32:263-70. 2013
    ..The drug cost and drug coverage may also be limiting factors for some patients. These aspects should be taken into account when making decisions regarding treatment options...
  30. doi request reprint Diet and effects of diet management on quality of life and symptoms in patients with irritable bowel syndrome
    Hege Ostgaard
    Department of Medicine, Stord Helse Fonna Hospital, Stord, Norway
    Mol Med Rep 5:1382-90. 2012
    ..Guidance on the management of diet improved their choice of a healthier diet, improved quality of life and reduced IBS symptoms...
  31. doi request reprint Increased serotonin transporter immunoreactivity intensity in the ileum of patients with irritable bowel disease
    Ingvild Wendelbo
    Section for Gastroenterology, Department of Medicine, Stord Helse Fonna Hospital, Stord 5416, Norway
    Mol Med Rep 9:180-4. 2014
    ..Serotonin acts upon sensory neurons in the submucosal and myenteric ganglia, as well as in the spinal cord, which is in agreement with this hypothesis. ..