Research Topics
Species | I RudbergSummaryAffiliation: Diakonhjemmet Hospital Country: Norway Publications
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Detail Information
Publications
[CYP genotyping in psychopharmacological treatment]Ida Rudberg
Psykofarmakologisk avdeling, Diakonhjemmet sykehus, 0319 Oslo
Tidsskr Nor Laegeforen 125:2953-5. 2005
Heterozygous mutation in CYP2C19 significantly increases the concentration/dose ratio of racemic citalopram and escitalopram (S-citalopram)Ida Rudberg
Department of Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway
Ther Drug Monit 28:102-5. 2006..Higher absolute serum concentrations indicate that this is not compensated for by dose reductions in clinical practice...
Impact of the ultrarapid CYP2C19*17 allele on serum concentration of escitalopram in psychiatric patientsI Rudberg
Department of Psychopharmacology, Diakonhjemmet Hospital, Oslo, Norway
Clin Pharmacol Ther 83:322-7. 2008..001). In conclusion, a homozygous CYP2C19*17 genotype is associated with lower serum concentration of escitalopram, which might imply increased risk of therapeutic failure...
Serum concentrations of sertraline and N-desmethyl sertraline in relation to CYP2C19 genotype in psychiatric patientsI Rudberg
Department of Psychopharmacology, Diakonhjemmet Hospital, P O Box 85 Vinderen, N 0319, Oslo, Norway
Eur J Clin Pharmacol 64:1181-8. 2008..To investigate the impact of CYP2C19 genotype on serum concentrations of sertraline and N-desmethyl sertraline in psychiatric patients...
Identification of a novel CYP2C19-mediated metabolic pathway of S-citalopram in vitroI Rudberg
Department of Psychopharmacology, Diakonhjemmet Hospital, N 0319 Oslo, Norway
Drug Metab Dispos 37:2340-8. 2009..Identification of SCIT PROP as a metabolic pathway catalyzed by CYP2C19 might explain why impaired CYP2C19 activity has a substantially larger effect on SCIT exposure than estimated from in vitro data based solely on formation of SDCIT...
The complexity of active metabolites in therapeutic drug monitoring of psychotropic drugsM Hendset
Department of Psychopharmacology, Diakonhjemmet Hospital, PO Box 85 Vinderen, 0319 Oslo, Norway
Pharmacopsychiatry 39:121-7. 2006..In addition, perspectives on the possibility of using distribution- and activity-weighted plasma concentrations are provided...
