Knut Erik Berge

Summary

Country: Norway

Publications

  1. doi Mutation S462P in the PCSK9 gene reduces secretion of mutant PCSK9 without affecting the autocatalytic cleavage
    Jamie Cameron
    Medical Genetics Laboratory, Department of Medical Genetics, Rikshospitalet University Hospital, NO 0027 Oslo, Norway
    Atherosclerosis 203:161-5. 2009
  2. doi Tangier disease caused by compound heterozygosity for ABCA1 mutations R282X and Y1532C
    Jamie Cameron
    Medical Genetics Laboratory, Department of Medical Genetics, Rikshospitalet, Oslo University Hospital, Oslo, Norway
    Atherosclerosis 209:163-6. 2010
  3. ncbi Sitosterolemia: a gateway to new knowledge about cholesterol metabolism
    Knut Erik Berge
    Department of Medical Genetics, Ullevaal University Hospital, Kirkeveien 166, NO 0407 Oslo, Norway
    Ann Med 35:502-11. 2003
  4. ncbi Human umbilical vein endothelial cells express complement receptor 1 (CD35) and complement receptor 4 (CD11c/CD18) in vitro
    Harald Langeggen
    Research Forum, Ulleval Hospital, University of Oslo, Norway
    Inflammation 26:103-10. 2002
  5. ncbi A daily glass of red wine: does it affect markers of inflammation?
    Lars Retterstol
    Department of Medical Genetics, Ulleval University Hospital, 0407 Oslo, Norway
    Alcohol Alcohol 40:102-5. 2005
  6. doi Identification of mutations in the apolipoprotein B-100 gene and in the PCSK9 gene as the cause of hypocholesterolemia
    Trond P Leren
    Medical Genetics Laboratory, Department of Medical Genetics, Rikshospitalet University Hospital, NO 0027 Oslo, Norway
    Clin Chim Acta 397:92-5. 2008
  7. doi Loss-of-function mutation R46L in the PCSK9 gene has little impact on the levels of total serum cholesterol in familial hypercholesterolemia heterozygotes
    Thea Bismo Strøm
    Medical Genetics Laboratory, Department of Medical Genetics, Oslo University Hospital Rikshospitalet, Oslo, Norway
    Clin Chim Acta 411:229-33. 2010
  8. ncbi [Lipid profile in children and adolescents with familial hypercholesterolemia]
    Trond P Leren
    Medisinsk genetisk laboratorium, Avdeling for medisinsk genetikk, Rikshospitalet Radiumhospitalet, 0027 Oslo
    Tidsskr Nor Laegeforen 127:2363-6. 2007

Collaborators

Detail Information

Publications8

  1. doi Mutation S462P in the PCSK9 gene reduces secretion of mutant PCSK9 without affecting the autocatalytic cleavage
    Jamie Cameron
    Medical Genetics Laboratory, Department of Medical Genetics, Rikshospitalet University Hospital, NO 0027 Oslo, Norway
    Atherosclerosis 203:161-5. 2009
    ..Characterization of how the naturally occurring mutations in the PCSK9 gene affect the function of PCSK9, may provide important insight into the mechanism by which PCSK9 degrades the LDL receptors...
  2. doi Tangier disease caused by compound heterozygosity for ABCA1 mutations R282X and Y1532C
    Jamie Cameron
    Medical Genetics Laboratory, Department of Medical Genetics, Rikshospitalet, Oslo University Hospital, Oslo, Norway
    Atherosclerosis 209:163-6. 2010
    ..Inherited low levels of high density lipoprotein (HDL) cholesterol may be due to mutations in the genes encoding the ATP-binding cassette transporter A1 (ABCA1), apolipoprotein (apo) A-I or lecithin:cholesterol acyltransferase (LCAT)...
  3. ncbi Sitosterolemia: a gateway to new knowledge about cholesterol metabolism
    Knut Erik Berge
    Department of Medical Genetics, Ullevaal University Hospital, Kirkeveien 166, NO 0407 Oslo, Norway
    Ann Med 35:502-11. 2003
    ..The elucidation of the gene defects responsible for sitosterolemia provides potential therapeutic targets for the treatment of hyperlipidemias in the general population...
  4. ncbi Human umbilical vein endothelial cells express complement receptor 1 (CD35) and complement receptor 4 (CD11c/CD18) in vitro
    Harald Langeggen
    Research Forum, Ulleval Hospital, University of Oslo, Norway
    Inflammation 26:103-10. 2002
    ..The presence of CR1 (CD35) and CR4 (CD1c/CD18) on HUVEC indicates that endothelial cells (EC) have the potential to bind C3b and iC3b, respectively, which both mediate biological effects in the course of complement activation...
  5. ncbi A daily glass of red wine: does it affect markers of inflammation?
    Lars Retterstol
    Department of Medical Genetics, Ulleval University Hospital, 0407 Oslo, Norway
    Alcohol Alcohol 40:102-5. 2005
    ..As inflammation is an important process in the progression of atherosclerosis, we hypothesized that the protective effect of red wine is partly mediated through a reduction in inflammation...
  6. doi Identification of mutations in the apolipoprotein B-100 gene and in the PCSK9 gene as the cause of hypocholesterolemia
    Trond P Leren
    Medical Genetics Laboratory, Department of Medical Genetics, Rikshospitalet University Hospital, NO 0027 Oslo, Norway
    Clin Chim Acta 397:92-5. 2008
    ..Characterization of the normally occurring mutations as the cause of hypocholesterolemia may increase our understanding of the normal lipid metabolism...
  7. doi Loss-of-function mutation R46L in the PCSK9 gene has little impact on the levels of total serum cholesterol in familial hypercholesterolemia heterozygotes
    Thea Bismo Strøm
    Medical Genetics Laboratory, Department of Medical Genetics, Oslo University Hospital Rikshospitalet, Oslo, Norway
    Clin Chim Acta 411:229-33. 2010
    ....
  8. ncbi [Lipid profile in children and adolescents with familial hypercholesterolemia]
    Trond P Leren
    Medisinsk genetisk laboratorium, Avdeling for medisinsk genetikk, Rikshospitalet Radiumhospitalet, 0027 Oslo
    Tidsskr Nor Laegeforen 127:2363-6. 2007
    ..Reasons are that the diagnosis may have been uncertain and that the reported lipid levels have been mainly from patients treated at tertiary referral centres...