Asensio Gonzalez

Summary

Affiliation: Northern Ireland

Publications

  1. doi Killer cell immunoglobulin-like receptor allele discrimination by high-resolution melting
    Asensio Gonzalez
    Northern Ireland Regional Histocompatibility and Immunogenetics Laboratory, Belfast City Hospital, Belfast, United Kingdom
    Hum Immunol 70:858-63. 2009
  2. doi Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5
    A Gonzalez
    Northern Ireland Regional Histocompatibility and Immunogenetics Laboratory, City Hospital, Belfast, UK
    Tissue Antigens 72:11-20. 2008
  3. ncbi Gene transcript amplification from cell lysates in continuous-flow microfluidic devices
    Asensio Gonzalez
    Northern Ireland Regional Histocompatibility and Immunogenetics Laboratory, Blood Transfusion Service, Belfast City Hospital, Belfast, BT9 7TS, and Stokes Research Institute, University of Limerick, Ireland, UK
    Biomed Microdevices 9:729-36. 2007
  4. ncbi Studies on the expression of the deleted KIR2DS4*003 gene product and distribution of KIR2DS4 deleted and nondeleted versions in different populations
    Derek Middleton
    Northern Ireland Regional Histocompatibility and Immunogenetics Laboratory, Belfast City Hospital, Belfast, Northern Ireland
    Hum Immunol 68:128-34. 2007
  5. doi Investigation of killer cell immunoglobulin-like receptor gene diversity, KIR2DL1 and KIR2DS1
    A Meenagh
    Northern Ireland Regional Histocompatibility and Immunogenetics Laboratory, City Hospital, Belfast, UK
    Tissue Antigens 72:383-91. 2008
  6. ncbi Segmenting fluid effect on PCR reactions in microfluidic platforms
    E J Walsh
    Stokes Research Institute, University of Limerick, Castletroy, Ireland
    Biomed Microdevices 7:269-72. 2005
  7. ncbi The three most common CARD15 mutations associated with Crohn's disease and the chromosome 16 susceptibility locus for systemic lupus erythematosus
    I Ferreiros-Vidal
    Research Laboratory 2, Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain
    Rheumatology (Oxford) 42:570-4. 2003
  8. doi Identification of a 2244 base pair interstitial deletion within the human ESR1 gene in the Spanish population
    J Jorge Galan
    Department of Structural Genomics, Neocodex SL, Seville, Spain
    J Med Genet 45:420-4. 2008
  9. ncbi Opposed independent effects and epistasis in the complex association of IRF5 to SLE
    I Ferreiro-Neira
    Laboratorio Investigacion 2 and Rheumatology Unit, Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain
    Genes Immun 8:429-38. 2007
  10. ncbi CARD15/NOD2 analysis in rheumatoid arthritis susceptibility
    I Ferreiros-Vidal
    Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain
    Rheumatology (Oxford) 42:1380-2. 2003

Collaborators

  • Derek Middleton
  • E Balada
  • I Ferreiros-Vidal
  • J J Gomez-Reino
  • A Ruiz
  • J Jorge Galan
  • F Esteban
  • A Meenagh
  • J L Royo
  • L M Real
  • C Dostal
  • J J Galan
  • J Rodriguez-Lopez
  • S Ruzickova
  • T Witte
  • E Endreffy
  • I Ferreiro-Neira
  • S Migliaresi
  • R Scorza
  • M Mavromati
  • M Marchini
  • F N Skopouli
  • G D Sebastiani
  • I Kappou-Rigatou
  • R E Schmidt
  • C Papasteriades
  • P Carreira
  • N Haruki
  • E J Walsh
  • F Barros
  • A Carracedo
  • N Strunnikova
  • P Jimenez-Gamiz
  • S Pedrinaci
  • S McQuaid
  • M Redondo
  • M Rodríguez-Sola
  • C Sleator
  • B Buch
  • M A Gonzalez-Moles
  • M del Carmen Rivero
  • R Moreno-Luna
  • M Serrano-Rios
  • A Salinas
  • R Ramirez-Lorca
  • A Gonzalez-Perez
  • E Guarducci
  • I Rego
  • N Barizzone
  • M Ruiz
  • M Liz
  • J Ordi-Ros
  • E Alonso-Perez
  • M Bijl
  • F J Blanco
  • C Krausz
  • F Nuti
  • M Pombo-Suarez
  • M Calaza
  • R Pullmann
  • S D'Alfonso
  • C G Kallenberg
  • A Kovacs
  • J D Minna
  • K S Kawaguchi
  • P P Massion
  • D P Carbone
  • R Grimes
  • A F Gazdar
  • C King
  • S Eichenberger
  • T P Dang
  • J L Pablos
  • J Garcia-Meijide
  • W Silk
  • K G Csaky
  • J Baffi
  • S W Cousins

Detail Information

Publications16

  1. doi Killer cell immunoglobulin-like receptor allele discrimination by high-resolution melting
    Asensio Gonzalez
    Northern Ireland Regional Histocompatibility and Immunogenetics Laboratory, Belfast City Hospital, Belfast, United Kingdom
    Hum Immunol 70:858-63. 2009
    ..The ongoing refinement of KIR haplotype distribution in our control population will help in disease association studies involving the KIR genes...
  2. doi Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5
    A Gonzalez
    Northern Ireland Regional Histocompatibility and Immunogenetics Laboratory, City Hospital, Belfast, UK
    Tissue Antigens 72:11-20. 2008
    ..This information complements published reports by our laboratory for allele-level typing of other KIR members, totaling 12 of the 17 known genes. These methods are allowing us to characterize KIR haplotypes in our population...
  3. ncbi Gene transcript amplification from cell lysates in continuous-flow microfluidic devices
    Asensio Gonzalez
    Northern Ireland Regional Histocompatibility and Immunogenetics Laboratory, Blood Transfusion Service, Belfast City Hospital, Belfast, BT9 7TS, and Stokes Research Institute, University of Limerick, Ireland, UK
    Biomed Microdevices 9:729-36. 2007
    ..The results prove the concept that the development of micro-total analysis systems (micro-TAS) for continuous gene expression directly from cell suspensions is viable with current technology...
  4. ncbi Studies on the expression of the deleted KIR2DS4*003 gene product and distribution of KIR2DS4 deleted and nondeleted versions in different populations
    Derek Middleton
    Northern Ireland Regional Histocompatibility and Immunogenetics Laboratory, Belfast City Hospital, Belfast, Northern Ireland
    Hum Immunol 68:128-34. 2007
    ..A trend was observed towards decreased frequencies of KIR2DS4 deleted variant occurrence in populations having KIR2DS4 as the only activating KIR gene...
  5. doi Investigation of killer cell immunoglobulin-like receptor gene diversity, KIR2DL1 and KIR2DS1
    A Meenagh
    Northern Ireland Regional Histocompatibility and Immunogenetics Laboratory, City Hospital, Belfast, UK
    Tissue Antigens 72:383-91. 2008
    ..Results also indicated an inherited KIR2DL1/2DS1 splice variant present in a haplotype with several core loci absent, in two families...
  6. ncbi Segmenting fluid effect on PCR reactions in microfluidic platforms
    E J Walsh
    Stokes Research Institute, University of Limerick, Castletroy, Ireland
    Biomed Microdevices 7:269-72. 2005
    ..The results are the first to provide a quantitative measure of segmenting fluid compatibility with PCR...
  7. ncbi The three most common CARD15 mutations associated with Crohn's disease and the chromosome 16 susceptibility locus for systemic lupus erythematosus
    I Ferreiros-Vidal
    Research Laboratory 2, Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain
    Rheumatology (Oxford) 42:570-4. 2003
    ....
  8. doi Identification of a 2244 base pair interstitial deletion within the human ESR1 gene in the Spanish population
    J Jorge Galan
    Department of Structural Genomics, Neocodex SL, Seville, Spain
    J Med Genet 45:420-4. 2008
    ..In the present study, we investigated whether the observed DHW is caused by structural variants present within the ESR1 gene...
  9. ncbi Opposed independent effects and epistasis in the complex association of IRF5 to SLE
    I Ferreiro-Neira
    Laboratorio Investigacion 2 and Rheumatology Unit, Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain
    Genes Immun 8:429-38. 2007
    ..In addition, we have found evidence for epistasis between known functional polymorphisms for the susceptibility effect...
  10. ncbi CARD15/NOD2 analysis in rheumatoid arthritis susceptibility
    I Ferreiros-Vidal
    Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain
    Rheumatology (Oxford) 42:1380-2. 2003
    ..To determine if the mutations in the CARD15/NOD2 gene predisposing to Crohn's disease (CD) contribute also to the genetic susceptibility to rheumatoid arthritis (RA)...
  11. ncbi CAPN10 alleles modify laryngeal cancer risk in the Spanish population
    F Esteban
    Servicio de Otorrinolaringologia, Hospital Universitario Virgen del Rocio, Avda Manuel Siurot s n, 41013 Sevilla, Spain
    Eur J Surg Oncol 34:94-9. 2008
    ..On the other hand, low circulating levels of IGF-1 have been recently found in patients with laryngeal carcinoma. Our objective was to examine the contribution of CAPN10 alleles to the development of laryngeal cancer...
  12. pmc Cloned fusion product from a rare t(15;19)(q13.2;p13.1) inhibit S phase in vitro
    N Haruki
    Department of Surgery, Nagoya City Hospital, Nagoya, Japan
    J Med Genet 42:558-64. 2005
    ..However, very few recurrent chromosomal translocations have been reported in more common epithelial tumours such as lung carcinomas...
  13. pmc Further evidence of the role of frizzled-related protein gene polymorphisms in osteoarthritis
    J Rodriguez-Lopez
    Laboratorio de Investigacion 2, Hospital Clinico Universitario de Santiago, Travesia de Choupana sn, 15706 Santiago de Compostela, Spain
    Ann Rheum Dis 66:1052-5. 2007
    ..To replicate the association of frizzled-related protein (FRZB) non-synonymous polymorphisms with osteoarthritis (OA) susceptibility...
  14. ncbi Bias in association studies of systemic lupus erythematosus susceptibility due to geographical variation in the frequency of a programmed cell death 1 polymorphism across Europe
    I Ferreiros-Vidal
    Laboratorio de Investigacion 2, Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain
    Genes Immun 8:138-46. 2007
    ..As allele frequency clines are common in other polymorphisms their impact in genetic epidemiology studies should be carefully considered...
  15. ncbi Molecular analysis of estrogen receptor alpha gene AGATA haplotype and SNP12 in European populations: potential protective effect for cryptorchidism and lack of association with male infertility
    J J Galan
    Department of Structural Genomics, Neocodex S L, Seville, Spain
    Hum Reprod 22:444-9. 2007
    ..In this ethnic group, single-nucleotide polymorphism 12 (SNP12) was concluded to be the tag SNP for the AGATA haplotype...
  16. ncbi Regulated heat shock protein 27 expression in human retinal pigment epithelium
    N Strunnikova
    Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892-1857, USA
    Invest Ophthalmol Vis Sci 42:2130-8. 2001
    ..It is hypothesized that Hsp27 levels may play a role in disease states in the retina, such as ARMD...