Research Topics

Kaijun Niu



  1. Hu S, Gu Y, Lu Z, Zhang Q, Liu L, Meng G, et al. Relationship Between Grip Strength and Prediabetes in a Large-Scale Adult Population. Am J Prev Med. 2019;: pubmed publisher
    ..20, 0.70, p<0.01). Increased grip strength is independently associated with lower prevalence of prediabetes in Chinese adults, suggesting that grip strength may be a useful marker for screening individuals at risk of prediabetes. ..
  2. Meng G, Wang L, Wang X, Chi V, Zhang Q, Liu L, et al. Association between neutrophil to lymphocyte ratio and depressive symptoms among Chinese adults: A population study from the TCLSIH cohort study. Psychoneuroendocrinology. 2019;103:76-82 pubmed publisher
    ..Further research is required to investigate this relationship with longitudinal data to establish the temporal ordering between these variables. ..
  3. Xia Y, Lu Z, Lu M, Liu M, Liu L, Meng G, et al. Raw orange intake is associated with higher prevalence of non-alcoholic fatty liver disease in an adult population. Nutrition. 2019;60:252-260 pubmed publisher
    ..02 (0.95-1.11) for 1 to 6 times per week, and 1.17 (1.03-1.33) for ≥7 times per week, respectively. The present study demonstrated that orange intake is positively associated with the prevalence of NAFLD. ..
  4. Niu K, Guo H, Guo Y, Ebihara S, Asada M, Ohrui T, et al. Royal jelly prevents the progression of sarcopenia in aged mice in vivo and in vitro. J Gerontol A Biol Sci Med Sci. 2013;68:1482-92 pubmed publisher
    ..These findings suggest that RJ/pRJ treatment had a beneficial effect on age-related sarcopenia. ..
  5. Yao Z, Gu Y, Zhang Q, Liu L, Meng G, Wu H, et al. Estimated daily quercetin intake and association with the prevalence of type 2 diabetes mellitus in Chinese adults. Eur J Nutr. 2019;58:819-830 pubmed publisher
    ..99), and 0.63 (0.51-0.94). The results of the present study showed that quercetin intake was inversely related to the prevalence of T2DM in the Chinese population, suggesting a protective effect of quercetin in the development of T2DM. ..
  6. Gu Y, Hu K, Huang Y, Zhang Q, Liu L, Meng G, et al. White blood cells count as an indicator to identify whether obesity leads to increased risk of type 2 diabetes. Diabetes Res Clin Pract. 2018;141:140-147 pubmed publisher
    ..22(1.03-1.44), 1.37(1.12-1.66) and 0.99(0.83-1.20), respectively. This study demonstrated that WBC count can be used as an indicator to identify whether or not obesity leads to increased risk of T2D. ..
  7. Wang X, Li Y, Li H, Gu Y, Song Y, Zhang Q, et al. Relationship of serum immunoglobulin levels to blood pressure and hypertension in an adult population. J Hum Hypertens. 2018;32:212-218 pubmed publisher
    ..83 (0.72-0.96), and 1.32 (1.15-1.51), respectively. Decreased IgM and increased IgG and IgA were related to a higher prevalence of hypertension. IgM was negatively correlated with BP, while IgG and IgA were positively correlated with BP. ..
  8. Meng Y, Wu H, Yang Y, Du H, Xia Y, Guo X, et al. Relationship of anabolic and catabolic biomarkers with muscle strength and physical performance in older adults: a population-based cross-sectional study. BMC Musculoskelet Disord. 2015;16:202 pubmed publisher
    ..In this study we did not observe that a combination of higher catabolic biomarkers and lower anabolic biomarkers were better predictors for muscle strength and physical performance. ..
  9. Niu K, Guo H, Kakizaki M, Cui Y, Ohmori Matsuda K, Guan L, et al. A tomato-rich diet is related to depressive symptoms among an elderly population aged 70 years and over: a population-based, cross-sectional analysis. J Affect Disord. 2013;144:165-70 pubmed publisher
    ..These results suggest that a tomato-rich diet may have a beneficial effect on the prevention of depressive symptoms. Further studies are needed to confirm these findings. ..

More Information


  1. Guo Y, Niu K, Okazaki T, Wu H, Yoshikawa T, Ohrui T, et al. Coffee treatment prevents the progression of sarcopenia in aged mice in vivo and in vitro. Exp Gerontol. 2014;50:1-8 pubmed publisher
    ..These findings suggest that the coffee treatment had a beneficial effect on age-related sarcopenia. ..
  2. Niu K, Momma H, Kobayashi Y, Guan L, Chujo M, Otomo A, et al. The traditional Japanese dietary pattern and longitudinal changes in cardiovascular disease risk factors in apparently healthy Japanese adults. Eur J Nutr. 2016;55:267-79 pubmed publisher
    ..A randomized trial is required to clarify the underlying mechanism. ..
  3. Wu H, Xia Y, Jiang J, Du H, Guo X, Liu X, et al. Effect of beta-hydroxy-beta-methylbutyrate supplementation on muscle loss in older adults: a systematic review and meta-analysis. Arch Gerontol Geriatr. 2015;61:168-75 pubmed publisher
    ..HMB supplementation may be useful in the prevention of muscle atrophy induced by bed rest or other factors. Further studies are needed to determine the precise effects of HMB on muscle strength and physical function in older adults. ..
  4. Yu B, He H, Zhang Q, Wu H, Du H, Liu L, et al. Soft drink consumption is associated with depressive symptoms among adults in China. J Affect Disord. 2015;172:422-7 pubmed publisher
    ..This is the first large cross-sectional study addressing this topic in an Asia population. ..
  5. Liu X, Zhang Q, Wu H, Du H, Liu L, Shi H, et al. Blood Neutrophil to Lymphocyte Ratio as a Predictor of Hypertension. Am J Hypertens. 2015;28:1339-46 pubmed publisher
    ..This result may be useful in elucidating the mechanism underlying the development of hypertension. New therapeutic approaches aimed at inflammation might be proposed to control hypertension and hypertensive damage. ..
  6. Guo X, Meng G, Liu F, Zhang Q, Liu L, Wu H, et al. Serum levels of immunoglobulins in an adult population and their relationship with type 2 diabetes. Diabetes Res Clin Pract. 2016;115:76-82 pubmed publisher
    ..Our findings indicate that the immunoglobulins might useful predictive factors for T2D in the general adult population. Further studies are needed to explore the causality and exact mechanisms of immunoglobulins in T2D. ..
  7. Zhang Q, Bao X, Meng G, Liu L, Wu H, Du H, et al. The predictive value of mean serum uric acid levels for developing prediabetes. Diabetes Res Clin Pract. 2016;118:79-89 pubmed publisher
    ..001). Mean SUA value was strongly and positively related to prediabetes risk, and showed better predictive ability for prediabetes than baseline SUA. ..
  8. Xia Y, Wang N, Yu B, Zhang Q, Liu L, Meng G, et al. Dietary patterns are associated with depressive symptoms among Chinese adults: a case-control study with propensity score matching. Eur J Nutr. 2017;56:2577-2587 pubmed publisher
  9. Meng G, Yang H, Bao X, Zhang Q, Liu L, Wu H, et al. Increased serum ferritin levels are independently related to incidence of prediabetes in adult populations. Diabetes Metab. 2017;43:146-153 pubmed publisher
    ..The relationship between prediabetes risk and mean serum ferritin levels may be more stable than one with baseline serum ferritin levels. ..
  10. Cui Y, Niu K, Huang C, Momma H, Guan L, Kobayashi Y, et al. Relationship between daily isoflavone intake and sleep in Japanese adults: a cross-sectional study. Nutr J. 2015;14:127 pubmed publisher
    ..002). Higher daily isoflavone intake was positively associated with optimal sleep duration and quality in a Japanese population. This finding suggests that daily isoflavone intake may have a potentially beneficial effect on sleep status. ..
  11. Meng G, Wang H, Pei Y, Li Y, Wu H, Song Y, et al. Effects of protease-treated royal jelly on muscle strength in elderly nursing home residents: A randomized, double-blind, placebo-controlled, dose-response study. Sci Rep. 2017;7:11416 pubmed publisher
    ..In addition, we have not found that pRJ intervention can achieve improvement or attenuating the decrease in physical performance. ..
  12. Yu B, Zhu Q, Meng G, Gu Y, Zhang Q, Liu L, et al. Habitual yoghurt consumption and depressive symptoms in a general population study of 19,596 adults. Eur J Nutr. 2018;57:2621-2628 pubmed publisher
    ..These results need to be interpreted with caution because of the cross-sectional nature of the data. ..
  13. Meng G, Zhang B, Yu F, Li C, Zhang Q, Liu L, et al. Soft drinks consumption is associated with nonalcoholic fatty liver disease independent of metabolic syndrome in Chinese population. Eur J Nutr. 2018;57:2113-2121 pubmed publisher
    ..These results suggest that reducing soft drinks consumption might be beneficial to the prevention of NAFLD. ..
  14. Meng G, Zhu Q, Shao J, Zhang Q, Liu L, Wu H, et al. Comparing the diagnostic ability of inflammatory markers in metabolic syndrome. Clin Chim Acta. 2017;475:1-6 pubmed publisher
    ..Further studies are encouraged to determine the efficacy of applying C3 to diagnosis and treatment in the clinical setting. ..
  15. Wang H, Song Y, Sun S, Gao L, Liu L, Meng G, et al. The association between immunoglobulin concentrations and prediabetes prevalence in a large Chinese cohort. Metabolism. 2017;73:77-84 pubmed publisher
    ..Further studies are necessary to clarify if there is a causal association of immunoglobulins in prediabetes or if they reflect early immunologic disturbances in these patients. ..
  16. Yu B, Yu F, Su Q, Zhang Q, Liu L, Meng G, et al. A J-shaped association between soy food intake and depressive symptoms in Chinese adults. Clin Nutr. 2018;37:1013-1018 pubmed publisher
    ..For the first time, the study provides evidence that light-to-moderate intake of soy food may reduce the incidence of depressive symptoms, while relatively high (≥twice/day) intake may generate the opposite effect. ..
  17. Wu H, Wei M, Zhang Q, Du H, Xia Y, Liu L, et al. Consumption of Chilies, but not Sweet Peppers, Is Positively Related to Handgrip Strength in an Adult Population. J Nutr Health Aging. 2016;20:546-52 pubmed publisher
    ..Further studies are necessary in order to determine whether there is a causal relationship between chili consumption frequency and muscle strength. ..