Effiong Akang

..This retrospective study analysed head and neck malignancies seen over a 19-year period at the University College Hospital, Ibadan...

..The good result of combined surgery and radiation regimens in this case demonstrates the usefulness of adjuvant radiation therapy in this condition...

..We decided to evaluate the hormone receptor status of patients seen in our practice to see if they indeed differ from that of other populations...

..Head and neck teratomas constitute about 10% of all cases. Only two cases of mature teratoma of the nasal septum have previously been documented in the world literature...

..Detection of the organism in gastric mucosal biopsies is important, hence the need to ascertain the optimal site for biopsy that will facilitate identification of the organism...

..05). The case-mortality rate was 11.4% at 1 month and 20% at 6 months post-operation and was significantly correlated with intracranial hypertension. Neither age nor sex affected the outcome (P>0.05)...

..In conclusion, this patient had left retinoblastoma with metastasis to the contralateral jaw. It is important to note that orbital Burkitt's lymphoma can be a differential diagnosis of retinoblastoma...

..05). From the result, it is inferred that maternal consumption of 500 ppm cyanide causes reduction in the cerebellar weight, vermal length and side-to-side dimension of the developing cerebellum in postnatal life in rats...

..Maternal cyanide consumption causes delayed maturation of the cerebellum, as evidenced by the thicker EGL, and reduction in the ML in the experimental group which become noticeable only at about 28th day of postnatal life...

..Due to reports that honey accelerates wound healing, an investigation on its role in wound contraction in fresh wounds inflicted on wistar rats was carried out...

..001 and 0.005 respectively). Healed wounds from the Ageratum group had significantly fewer fibroblasts than honey and controls (p = 0.012 and 0.036 respectively)...

..The aim of this prospective study was to assess the usefulness of nasal smear eosinophilia compared with a skin sensitivity test for the diagnosis of allergic rhinitis and to determine the degree of correlation between the tests...

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..The purpose of this case report is to reiterate the importance of a high index of suspicion in the approach to the management of head and neck swellings...

..Protein kinase C-beta (PKC-beta) is a cell-signaling intermediate implicated in development of diabetic complications...

..However, studies from Africa on intraoral salivary gland neoplasms are relatively sparse in the medical literature...

..Tumours are uncommon in childhood; malignancies are even more uncommon. Yet malignancies are among the leading causes of childhood death in many parts of the world. The pattern of these tumours in Benin City Nigeria, however, is not known...

..To determine the relationship between tear function and ocular surface abnormalities with subjective symptoms of dry eye...

..Increased knowledge of radiation-related breast cancer and modifying influences plays an important role in guiding the initial treatment approach for young women and optimizing long-term follow-up care...

..In contrast to an earlier study from University College Hospital, Ibadan, the present study has revealed a predominance of accidental and homicidal deaths, with a relatively lower rate of maternal deaths...

..65 (per 10(3)/muL increase, P = .002). These findings demonstrate that metabolic syndrome is prevalent among nondiabetic PD patients and that WBC count is strongly associated with metabolic syndrome and its components...

..Tear instability is associated with symptoms of ocular discomfort and irritation. Many patients with dry eyes remain untreated due to improper diagnoses...

..To retrospectively evaluate the clinicopathological features, treatment modalities and factors affecting prognosis in patients with both conjunctival intraepithelial and invasive squamous neoplasms...

..In addition, prospective population-based studies are required to determine the national incidence and to identify risk factors for head and neck cancer in the Nigerian population...

..The results obtained in this study suggest the relative safety of short-term use of preparations containing E. chlorantha, a very popular antimalarial herbal remedy in Southern Nigeria...

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..3%) of the lesions in the eyelid. However, squamous cell carcinomas were the commonest lesions of the conjunctiva seen accounting for 25% of these. Retinoblastomas formed 95.7% of the intra-ocular tumours seen...

..Late clinical presentation and high postoperative mortality are responsible for the persistently poor prognosis of oesophageal carcinoma despite significant advances in the diagnosis and management of these neoplasms...

..To describe the clinical and histopathologic features of a patient with viral retinitis secondary to subacute sclerosing panencephalitis...

..Whether these changes reflect actual changes in the distribution of childhood cancer in the local population will require further study...

..We present the case of recurrent rhinosporidiosis in a 16 year old girl a year after polypectomy in Zaria, northern Nigeria...

..Rare histological variants of prostatic cancer encountered in the present study included a case each of mucinous carcinoma, transitional cell carcinoma and rhabdomyosarcoma...

..In two cases there was rupture of the inflammatory pseudotumour through the anterior abdominal wall...

..One-fifth of the children had complex malformations of multiple organ systems, 20% of which were associated with chromosomal anomalies, rubella, and other malformation syndromes...

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..We suggest that cerebrospinal fluid from meningitis cases must be cultured using Sabouraud dextrose agar and any growth on the agar must be examined using Indian ink...

..Eighty-eight per cent of the teratomas reviewed histologically were classified as mature, a further 8% were immature, and 4% were malignant...

..The authors recommend systemic cytotoxic chemotherapy and local radiotherapy for patients with late stages of CTCL as mainstay of treatment...

..Both malignant neoplasms arose in the sacrococcygeal region and occurred in patients relatively older than those with benign sacrococcygeal teratomas. These two malignant teratomas contained yolk sac elements...

..Our findings indicate an unfavourable prognosis for nephroblastoma in this environment because of late clinical presentation with advanced disease and inadequate treatment and follow-up...

..In an era of medical audit and scarce human and financial resources, the wisdom of routine endometrial biopsy in all women with infertility and those with abnormal uterine bleeding who are younger than 40 years, is called to question...

..Malignant lymphoma arising from the uterine cervix is a very rare entity. Only two such patients have been reported as pregnant at the time of diagnosis...

..In contrast to previous studies, Burkitt's lymphoma affected the mandible more commonly than the maxilla. The relative frequency of primary malignant bone tumours is low in our environment as observed in other developing countries...

..CONCLUSION: The present study, the first in an indigenous African population, supports other studies that have shown a positive association between obesity and breast cancer risk among postmenopausal women...

..The case presented highlights the varied clinical presentation of DLB, and is intended to raise awareness about another possible cause of dementia in Nigerian subjects...

..Patient died while being prepared for surgery and autopsy confirmed an immature teratoma. The clinical and pathological characteristics of paediatric cervical teratomas are discussed...

..In Ibadan, it seems that what appeared to be minor changes might actually be a real decline in the incidence of Burkitt's lymphoma and that it might be partly ascribed to improved living conditions and greater control of malaria...

..It is suggested that colonoscopic examination with adequate biopsy should be performed in patients with chronic diarrhoea with no aetiologic agent identified...

..The history of measles and persistent diarrhoea appear to increase the risk of VAD. The simplicity, sensitivity and specificity of CIC-T suggest that this procedure is a good screening tool for epidemiological survey of vitamin A status...

..These factors explain the relatively low survival figures in the present study, as compared to higher survival figures in white patients with mucoepidermoid carcinoma...

..It is hoped that this case report will heighten the awareness of clinicians and pathologists in the recognition of this unusual condition...

..Flexner-Wintersteiner rosettes occurred in 61% and optic nerve involvement in 78% of the cases and the sites of predilection were regional lymph nodes, scalp, jaw, brain, skull, long bones, and gum...

..Therefore, renal biopsy is recommended as a prelude to a trial of steroid therapy in these patients since MCN (which is generally associated with steroid-responsiveness) is an uncommon finding among them...

..The youngest patient was aged 17 years, indicating the need tare cancer screening among adolescents and a vigorous family planning programme that emphasizes barrier contraception...

..This study emphasises the need for a high clinical index of suspicion to improve the antemortem diagnosis of this potentially fatal condition and to advocate a greater use of prophylactic anti-coagulant therapy in high risk patients...

..Influence of height on breast cancer risk was quite strong in this cohort of indigenous Africans, which suggests that energy intake during childhood may be important in breast cancer development...

..It can arise as a result of osseous metaplasia in a pre-existing benign or malignant neoplasm of the breast or as non-phylloides sarcoma from the soft tissue of a previously normal breast...

..Cavernous lymphangioma is a rare lesion in the breast of adults. Only a few cases have been documented in literature...