P Niemeyer

Summary

Publications

  1. ncbi request reprint Fracture treatment in the elderly
    P Niemeyer
    Department of Traumatology and Orthopedic Surgery, Albert Ludwig University, Freiburg, Germany
    Acta Chir Orthop Traumatol Cech 71:329-38. 2004
  2. ncbi request reprint Influence of platelet-rich plasma on osteogenic differentiation of mesenchymal stem cells and ectopic bone formation in calcium phosphate ceramics
    Philip Kasten
    Division of Experimental Orthopaedics, Orthopaedic University Hospital Heidelberg, Heidelberg, Germany
    Cells Tissues Organs 183:68-79. 2006
  3. ncbi request reprint Anatomical refixation for acute ruptures of the distal biceps tendon using a novel transcortical refixation system
    Philipp Niemeyer
    Department for Orthopedic and Trauma Surgery, University Hospital Freiburg, Hugstetter Strasse 55, Freiburg i Br, Germany
    Arch Orthop Trauma Surg 128:573-81. 2008
  4. ncbi request reprint Mesenchymal stem cell-based HLA-independent cell therapy for tissue engineering of bone and cartilage
    Philipp Niemeyer
    Department of Orthopaedic Surgery and Traumatology, Freiburg University Hospital, Germany
    Curr Stem Cell Res Ther 1:21-7. 2006
  5. doi request reprint Transplantation of human mesenchymal stem cells in a non-autogenous setting for bone regeneration in a rabbit critical-size defect model
    P Niemeyer
    Department of Orthopedic Surgery and Traumatology, Freiburg University Hospital, Germany
    Acta Biomater 6:900-8. 2010
  6. ncbi request reprint Comparison of immunological properties of bone marrow stromal cells and adipose tissue-derived stem cells before and after osteogenic differentiation in vitro
    Philipp Niemeyer
    Department of Orthopaedic Surgery and Traumatology, University of Freiburg, Germany
    Tissue Eng 13:111-21. 2007
  7. ncbi request reprint [Clinical, radiological and arthroscopical aspects in nail patella syndrome. Literature review based on an affected family]
    P Niemeyer
    Department für Orthopädie und Traumatologie, Universitatsklinikum Freiburg
    Orthopade 35:197-203. 2006
  8. ncbi request reprint [Adult mesenchymal stem cells for the regeneration of musculoskeletal tissue]
    P Niemeyer
    Klinik für Traumatologie, Universitatsklinikum Freiburg
    MMW Fortschr Med 146:45. 2004
  9. ncbi request reprint [Adult mesenchymal stem cells for the regeneration of musculoskeletal tissue]
    P Niemeyer
    Department für Orthopädie und Traumatologie, Klinik für Traumatologie, Albert Ludwigs Universitat Freiburg
    MMW Fortschr Med 146:107-13. 2004
  10. ncbi request reprint [Allogenic transplantation of human mesenchymal stem cells for tissue engineering purposes: an in vitro study]
    P Niemeyer
    Department für Orthopädie und Traumatologie, Klinik für Traumatologie, Universitatsklinikum Freiburg
    Orthopade 33:1346-53. 2004

Detail Information

Publications36

  1. ncbi request reprint Fracture treatment in the elderly
    P Niemeyer
    Department of Traumatology and Orthopedic Surgery, Albert Ludwig University, Freiburg, Germany
    Acta Chir Orthop Traumatol Cech 71:329-38. 2004
    ..Therefore, therapy of fractures in these typical locations shall in recognition of the particular characteristics of the advanced age be displayed in this article...
  2. ncbi request reprint Influence of platelet-rich plasma on osteogenic differentiation of mesenchymal stem cells and ectopic bone formation in calcium phosphate ceramics
    Philip Kasten
    Division of Experimental Orthopaedics, Orthopaedic University Hospital Heidelberg, Heidelberg, Germany
    Cells Tissues Organs 183:68-79. 2006
    ..In conclusion, the effect of PRP depended on the type of ceramic and the differentiation status of the MSC, and enhanced ALP activity of MSC on the high surface scaffold CDHA only, but PRP did not improve osteogenesis in our setting...
  3. ncbi request reprint Anatomical refixation for acute ruptures of the distal biceps tendon using a novel transcortical refixation system
    Philipp Niemeyer
    Department for Orthopedic and Trauma Surgery, University Hospital Freiburg, Hugstetter Strasse 55, Freiburg i Br, Germany
    Arch Orthop Trauma Surg 128:573-81. 2008
    ..In addition, we introduce position-dependent isometric myometry to allow quantitative measures of post-operative strength at specific elbow joint positions, for improved comparative analyses...
  4. ncbi request reprint Mesenchymal stem cell-based HLA-independent cell therapy for tissue engineering of bone and cartilage
    Philipp Niemeyer
    Department of Orthopaedic Surgery and Traumatology, Freiburg University Hospital, Germany
    Curr Stem Cell Res Ther 1:21-7. 2006
    ..Only then can it be shown whether the associated high expectations are justified...
  5. doi request reprint Transplantation of human mesenchymal stem cells in a non-autogenous setting for bone regeneration in a rabbit critical-size defect model
    P Niemeyer
    Department of Orthopedic Surgery and Traumatology, Freiburg University Hospital, Germany
    Acta Biomater 6:900-8. 2010
    ..While previous papers suggest the use of non-autogenous hMSC cells for tissue engineering purposes, the present results show inferior clinical results from transplantation of hMSC in a xenogenic setting compared with autogenous MSC...
  6. ncbi request reprint Comparison of immunological properties of bone marrow stromal cells and adipose tissue-derived stem cells before and after osteogenic differentiation in vitro
    Philipp Niemeyer
    Department of Orthopaedic Surgery and Traumatology, University of Freiburg, Germany
    Tissue Eng 13:111-21. 2007
    ..Our results suggest that allogenic transplantation of BMSCs and ASCs would be possible, for example, in the context of tissue engineering...
  7. ncbi request reprint [Clinical, radiological and arthroscopical aspects in nail patella syndrome. Literature review based on an affected family]
    P Niemeyer
    Department für Orthopädie und Traumatologie, Universitatsklinikum Freiburg
    Orthopade 35:197-203. 2006
    ..Therefore, in cases of unspecific knee pain associated with NPS arthroscopy of the knee joints and plicae resection seems to be recommendable...
  8. ncbi request reprint [Adult mesenchymal stem cells for the regeneration of musculoskeletal tissue]
    P Niemeyer
    Klinik für Traumatologie, Universitatsklinikum Freiburg
    MMW Fortschr Med 146:45. 2004
  9. ncbi request reprint [Adult mesenchymal stem cells for the regeneration of musculoskeletal tissue]
    P Niemeyer
    Department für Orthopädie und Traumatologie, Klinik für Traumatologie, Albert Ludwigs Universitat Freiburg
    MMW Fortschr Med 146:107-13. 2004
    ..Only then can it be shown whether the associated high expectations are justified...
  10. ncbi request reprint [Allogenic transplantation of human mesenchymal stem cells for tissue engineering purposes: an in vitro study]
    P Niemeyer
    Department für Orthopädie und Traumatologie, Klinik für Traumatologie, Universitatsklinikum Freiburg
    Orthopade 33:1346-53. 2004
    ..Our results support the hypothesis that MSC are immunoprivileged cells which are potentially at disposal for HLA-incompatible cell replacement therapies...
  11. ncbi request reprint Survival of human mesenchymal stromal cells from bone marrow and adipose tissue after xenogenic transplantation in immunocompetent mice
    P Niemeyer
    Department of Orthopedic Surgery and Traumatology, Freiburg University Hospital, Freiburg, Germany
    Cytotherapy 10:784-95. 2008
    ..The purpose of the current paper was to evaluate the survival of undifferentiated and osteogenically induced human MSC from different origins after transplantation in immunocompetent mice...
  12. doi request reprint [Novel software-based and validated evaluation method for objective quantification of bone regeneration in experimental bone defects]
    T Schonberger
    Department für Orthopädie und Traumatologie, Universitatsklinikum Freiburg, Freiburg
    Z Orthop Unfall 148:19-25. 2010
    ....
  13. ncbi request reprint Transplantation of mesenchymal stromal cells on mineralized collagen leads to ectopic matrix synthesis in vivo independently from prior in vitro differentiation
    P Niemeyer
    Department of Orthopaedic Surgery and Traumatology, Freiburg University Hospital, Freiburg, Germany
    Cytotherapy 8:354-66. 2006
    ..It still remains unclear if there is a benefit of in vitro differentiation of MSC prior to transplantation or if undifferentiated MSC hold the optimal potential concerning new tissue formation...
  14. doi request reprint [In vitro study on the influence of fibrin in cartilage constructs based on PGA fleece materials]
    H Schmal
    Department für Orthopädie und Traumatologie, Universitatsklinik Freiburg, Hugstetter Strasse 55, 79106 Freiburg im Breisgau
    Orthopade 37:424-34. 2008
    ..The matrix component in autologous chondrocyte implantation plays an important role. In this study the influence of an additional fibrin component in cartilage constructs based on polyglycolide polymers (PGA) was investigated...
  15. ncbi request reprint Differential expression pattern of extracellular matrix molecules during chondrogenesis of mesenchymal stem cells from bone marrow and adipose tissue
    A T Mehlhorn
    Department of Orthopaedic and Trauma Surgery, University Medical Center, Albert Ludwigs University, Freiburg, Germany
    Tissue Eng 12:2853-62. 2006
    ..These findings may direct the development of a cell-specific culture environment either to prevent hypertrophy in BMSCs or to promote chondrogenic maturation in ADASCs...
  16. doi request reprint Microporous calcium phosphate ceramics as tissue engineering scaffolds for the repair of osteochondral defects: biomechanical results
    H O Mayr
    Department of Orthopedic and Trauma Surgery, Albert Ludwig University of Freiburg, Freiburg, Germany
    Acta Biomater 9:4845-55. 2013
    ..However, the central area of the implants had a lower ICRS score than healthy cartilage. Microporous TCP was almost fully resorbed at 52 weeks and replaced by bone...
  17. ncbi request reprint Clinical outcome following the first-line, single lesion microfracture at the knee joint
    G M Salzmann
    Department of Orthopaedic and Trauma Surgery, University Medical Center, Albert Ludwigs University Freiburg, Hugstetter Strasse 55, Freiburg, Germany
    Arch Orthop Trauma Surg 133:303-10. 2013
    ..Case series: Level of evidence, 4...
  18. ncbi request reprint [Operative treatment of cartilage lesions in the knee joint]
    P Niemeyer
    Department für Orthopädie und Traumatologie, Universitatsklinikum Freiburg
    Sportverletz Sportschaden 21:41-50. 2007
    ....
  19. ncbi request reprint Tibial wedge osteotomy for osteochondral transplantation in talar lesions
    P C Kreuz
    Department of Orthopedic and Trauma Surgery, University Medical Center Freiburg, Freiburg, Germany
    Int J Sports Med 29:584-9. 2008
    ..Osteochondral grafting with temporary removal of a tibial bone block is a successful technique with good midterm results in osteochondral talar lesions for which arthroscopic excision, curettage and drilling has failed...
  20. doi request reprint Cartilage repair approach and treatment characteristics across the knee joint: a European survey
    Gian M Salzmann
    Department of Orthopaedic and Trauma Surgery, University Medical Centre, Albert Ludwigs University Freiburg, Freiburg, Germany
    Arch Orthop Trauma Surg 131:283-91. 2011
    ..To describe indication, approach and treatment modalities for the management of knee cartilage lesions among a selected European population...
  21. doi request reprint Human neonatal thymus-derived mesenchymal stromal cells: characterization, differentiation, and immunomodulatory properties
    Matthias Siepe
    Department of Cardiovascular Surgery, University Medical Center Freiburg, Freiburg, Germany
    Tissue Eng Part A 15:1787-96. 2009
    ..Our results confirm that the neonatal thymus contains mesenchymal stromal cells (nTMSC) with full mesenchymal differentiation potential and immunomodulatory properties...
  22. doi request reprint [Cartilage biopsy for autologous chondrocyte implantation (ACI)]
    J M Pestka
    Department für Orthopädie und Traumatologie, Universitatsklinikum Freiburg, Hugstetter Straße 55, Freiburg
    Z Orthop Unfall 151:278-83. 2013
    ..The article describes the relevant aspects of the biopsy in the context of ACI with regard to the literature available. Follow-up studies to better define and standardise the cartilage biopsy process are thus required. ..
  23. doi request reprint Reoperative characteristics after microfracture of knee cartilage lesions in 454 patients
    G M Salzmann
    Department of Orthopaedic and Trauma Surgery, University Medical Center, Albert Ludwigs University Freiburg, Hugstetter Strasse 55, 79106, Freiburg, Germany
    Knee Surg Sports Traumatol Arthrosc 21:365-71. 2013
    ..There is only limited information on those patients who fail following microfracture treatment at the knee joint. Evaluation was made of factors associated with treatment failure and clinical outcome assessment among this collective...
  24. ncbi request reprint Evaluation of Singh index for assessment of osteoporosis using digital radiography
    O Hauschild
    Department of Orthopaedic Surgery and Traumatology, University Medical Center Freiburg, Hugstetter Str 55, Freiburg i Breisgau D 79106, Germany
    Eur J Radiol 71:152-8. 2009
    ..Even though we found reasonable intraobserver agreement assessment of SI is highly subjective and interobserver agreement is generally poor. Moreover, using digital radiography could not improve correlation with DXA measurements...
  25. doi request reprint Comparison of mesenchymal stem cells from bone marrow and adipose tissue for bone regeneration in a critical size defect of the sheep tibia and the influence of platelet-rich plasma
    Philipp Niemeyer
    Department of Orthopedic Surgery and Traumatology, Freiburg University Hospital, Freiburg, Germany
    Biomaterials 31:3572-9. 2010
    ..Histological analysis confirmed radiographic evaluation finding analogous significances. In conclusion, ASC seem to be inferior to BMSC in terms of their osteogenic potential but that can partially be compensated by the addition of PRP...
  26. doi request reprint Xenogenic transplantation of human mesenchymal stem cells in a critical size defect of the sheep tibia for bone regeneration
    Philipp Niemeyer
    Department of Orthopedic Surgery and Traumatolgy, Freiburg University Hospital, Freiburg, Germany
    Tissue Eng Part A 16:33-43. 2010
    ....
  27. doi request reprint [Factors that influence clinical outcome following autologous chondrocyte implantation for cartilage defects of the knee]
    P Niemeyer
    Department für Orthopädie und Traumatologie, Universitatsklinikum Freiburg, Hugstetterstrasse 55, Freiburg
    Z Orthop Unfall 150:83-8. 2012
    ..The aim of the present review article is to summarise factors that affect clinical outcome following ACI for treatment of symptomatic cartilage defects of the knee based upon the scientific literature available on this topic...
  28. ncbi request reprint Principles and clinical application of the locking compression plate (LCP)
    P Niemeyer
    Department of Orthopedic Surgery and Traumatology Freiburg University Hospital, Freiburg i Br, Germany
    Acta Chir Orthop Traumatol Cech 73:221-8. 2006
    ..The current article provides biomechanical background to and guidelines for the use of LC plates in the operative treatment of fractures and also reports experimental and clinical results obtained with LCP...
  29. ncbi request reprint Technical note: the "double eye" technique as a modification of autologous chondrocyte implantation for the treatment of retropatellar cartilage defects
    Philipp Niemeyer
    Department of Orthopedic Surgery and Traumatology, Freiburg University Hospital, Hugstetter Str 55, 79095, Freiburg i Br, Germany
    Knee Surg Sports Traumatol Arthrosc 15:1461-8. 2007
    ..The procedure needs further evaluation in clinical studies involving larger numbers of patients so that the indications can be determined more precisely...
  30. ncbi request reprint Is microfracture of chondral defects in the knee associated with different results in patients aged 40 years or younger?
    Peter C Kreuz
    Department of Orthopaedic and Trauma Surgery, Albert Ludwig University of Freiburg, Freiburg, Germany
    Arthroscopy 22:1180-6. 2006
    ..This prospective study was performed to discover age-dependent differences in the results after microfracture over a period of 36 months...
  31. doi request reprint Characteristic complications after autologous chondrocyte implantation for cartilage defects of the knee joint
    Philipp Niemeyer
    Department of Orthopaedic Surgery and Traumatology, Freiburg University Hospital, Freiburg im Breisgau, Germany
    Am J Sports Med 36:2091-9. 2008
    ..Although autologous chondrocyte implantation (ACI) is a well-established therapy for the treatment of isolated cartilage defects of the knee joint, little is known about typical complications and their treatment after ACI...
  32. ncbi request reprint Isolated and combined tears of the subscapularis tendon
    Peter C Kreuz
    Department of Orthopaedic Surgery, Kantonsspital St Gallen, St Gallen, Switzerland
    Am J Sports Med 33:1831-7. 2005
    ..Isolated and combined subscapularis tendon tears are rare and are described in the literature only in small numbers...
  33. doi request reprint The effect of platelet-rich plasma on healing in critical-size long-bone defects
    Philip Kasten
    Orthopaedic Surgery Hospital, University of Heidelberg, Schlierbacher Landstrasse 200a, 69118 Heidelberg, Germany
    Biomaterials 29:3983-92. 2008
    ..In conclusion, PRP improves bone healing in a diaphyseal rabbit model on CDHA and the combination of CDHA. This study supports the allogenic use of PRP for bone healing as an off-the-shelf therapy...
  34. ncbi request reprint Mosaicplasty with autogenous talar autograft for osteochondral lesions of the talus after failed primary arthroscopic management: a prospective study with a 4-year follow-up
    Peter Cornelius Kreuz
    Department of Orthopaedic Surgery, Albert Ludwig University of Freiburg, Hugstetter Str 55, 79106 Freiburg, Germany
    Am J Sports Med 34:55-63. 2006
    ..There have been limited data in the literature reporting the results of osteochondral autografting for osteochondral lesions of the talus that have failed arthroscopic treatment...
  35. ncbi request reprint Evaluation of mineralized collagen and alpha-tricalcium phosphate as scaffolds for tissue engineering of bone using human mesenchymal stem cells
    Philipp Niemeyer
    Department of Orthopedic Surgery, University of Heidelberg, Heidelberg, Germany
    Cells Tissues Organs 177:68-78. 2004
    ..TCP = 0.046) and 3D cell alignment (cell infiltration up to 500 vs. 200 microm). In conclusion, our data suggest that mineralized collagen is a promising candidate for use as a scaffold in tissue engineering of bone...