Randomized trial comparing polymer-coated extended-release morphine sulfate to controlled-release oxycodone HCl in moderate to severe nonmalignant painBruce Nicholson
Pain Specialists of Greater Lehigh Valley, 1240 South Cedar Crest Boulevard, Allentown, PA 18103, USA
Curr Med Res Opin 22:1503-14. 2006
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Comorbidities in chronic neuropathic painBruce Nicholson
Pennsylvania State University School of Medicine, Allentown, Pennsylvania 18103, USA
Pain Med 5:S9-S27. 2004
..In this way, functionality may be restored and the patient's quality of life improved...
Morphine sulfate extended-release capsules for the treatment of chronic, moderate-to-severe painBruce Nicholson
Pain Specialists of Greater Lehigh Valley, 1240 South Cedar Crest Boulevard, Suite 307, Allentown, PA 18103, USA
Expert Opin Pharmacother 9:1585-94. 2008
..The flexibility available with morphine sulfate extended-release capsules may offer clinical advantages for pain management...
Treatment of chronic moderate-to-severe non-malignant pain with polymer-coated extended-release morphine sulfate capsulesBruce Nicholson
Pain Specialists of Greater Lehigh Valley, Allentown, Pennsylvania 18103, USA
Curr Med Res Opin 22:539-50. 2006
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Management of chronic noncancer pain in the primary care settingBruce Nicholson
Pain Specialists of Greater Lehigh Valley, Allentown, PA 18103, USA
South Med J 100:1028-36. 2007
..Ongoing monitoring should focus on the 4 A's (ie, analgesia, activities of daily living, adverse effects, and aberrant drug-related behaviors), and all aspects of patient care must be thoroughly documented...
Benefits of extended-release opioid analgesic formulations in the treatment of chronic painBruce Nicholson
Pennsylvania State University School of Medicine, Division of Pain Medicine, Lehigh Valley Hospital and Health Network, Allentown, Pennsylvania 18103, USA
Pain Pract 9:71-81. 2009
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Responsible prescribing of opioids for the management of chronic painBruce Nicholson
Lehigh Valley Hospital Pain Center, Allentown, Pennsylvania, USA
Drugs 63:17-32. 2003
..Further controlled clinical trials are needed to define the role of opioid therapy in chronic non-cancer pain, and to establish criteria for patient selection and specific treatment algorithms...
Opioid delivery in the treatment of cancer breakthrough pain: a review of routes of administrationBruce Nicholson
Division of Pain Medicine, Pain Specialists of Greater Lehigh Valley, Pennsylvania, USA
J Opioid Manag 7:69-79. 2011
..The purpose of this review is to provide an overview of the different routes of opioid administration used in the treatment of cancer BTP and briefly discuss the characteristics of different delivery systems...
Primary care considerations of the pharmacokinetics and clinical use of extended-release opioids in treating patients with chronic noncancer painBruce Nicholson
Division of Pain Medicine, Lehigh Valley Health Network, Allentown, PA 18103, USA
Postgrad Med 125:115-27. 2013
..This article provides a comprehensive review of the PK and clinical effects of ER opioids and discusses novel ER opioid formulations that may limit abuse potential...
Differential diagnosis: nociceptive and neuropathic painBruce Nicholson
Penn State School of Medicine, Division of Pain Medicine, Lehigh Valley Hospital and Health Network, 1240 S Cedar Crest Blvd, Ste 307, Allentown, PA 18103, USA
Am J Manag Care 12:S256-62. 2006
..Patients with painful DPN, PHN, or cancer may present with a variety of acute or chronic NP symptoms, and it is important to distinguish these conditions from other pain syndromes so that appropriate therapy can be initiated...
Treatment of painful polyneuropathiesBruce Nicholson
Penn State School of Medicine, Division of Pain Medicine, Lehigh Valley Hospital and Health Network, 1240 South Cedar Crest Boulevard, Suite 307, Allentown, PA 18103, USA
Curr Pain Headache Rep 9:178-83. 2005
..New antiepileptics, antidepressants, and topical therapies have contributed to improved patient outcomes...
The management of pain in arthritis and the use of cyclooxygenase-2 inhibitors: new paradigms and insightsEdgar Ross
Pain Management Center, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Curr Pain Headache Rep 8:518-22. 2004
..Despite this optimistic outlook, pain often is a significant problem and should be treated whenever it becomes a barrier to function...