N P Nguyen

Summary

Publications

  1. Popescu T, Karlsson U, Vinh Hung V, Trigo L, Thariat J, Vuong T, et al. Challenges Facing Radiation Oncologists in The Management of Older Cancer Patients: Consensus of The International Geriatric Radiotherapy Group. Cancers (Basel). 2019;11: pubmed publisher
    ..7. The role of systemic therapy alone or combined with radiotherapy for frail patients needs to be defined in future clinical trials because of targeted agents or immunotherapy may be less toxic compared to conventional chemotherapy. ..
  2. Nguyen N, Vock J, Chi A, Vinh Hung V, Dutta S, Ewell L, et al. Impact of intensity-modulated and image-guided radiotherapy on elderly patients undergoing chemoradiation for locally advanced head and neck cancer. Strahlenther Onkol. 2012;188:677-83 pubmed publisher
    ..Compared to younger patients, elderly patients with locally advanced head and neck cancer tolerated chemoradiation with IMRT and IGRT well, and should not be denied curative treatment based solely on age. ..
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    Nguyen N, Smith H, Dutta S, Alfieri A, North D, Nguyen P, et al. Aspiration occurence during chemoradiation for head and neck cancer. Anticancer Res. 2007;27:1669-72 pubmed
    ..Despite broad-spectrum antibiotics and supportive care, six patients (5%) died. Aspiration may develop during chemoradiation for head and neck cancer because of radiation-induced altered swallow. ..
  4. Nguyen N, Garland L, Welsh J, Hamilton R, Cohen D, Vinh Hung V. Can stereotactic fractionated radiation therapy become the standard of care for early stage non-small cell lung carcinoma. Cancer Treat Rev. 2008;34:719-27 pubmed publisher
    ..Stereotactic body radiation therapy may become standard of care for operable early stages non-small cell lung cancer. ..
  5. Nguyen N, Chi A, Betz M, Almeida F, Vos P, Davis R, et al. Feasibility of intensity-modulated and image-guided radiotherapy for functional organ preservation in locally advanced laryngeal cancer. PLoS ONE. 2012;7:e42729 pubmed publisher
    ..However, dysphagia and aspiration remain serious complications, due most likely to high radiation dose delivery to the pharyngeal musculatures. ..
  6. Nguyen N, Abraham D, Desai A, Betz M, Davis R, Sroka T, et al. Impact of image-guided radiotherapy to reduce laryngeal edema following treatment for non-laryngeal and non-hypopharyngeal head and neck cancers. Oral Oncol. 2011;47:900-4 pubmed publisher
    ..IGRT results in low rates and low severity of laryngeal edema following treatment for non-laryngeal and non-hypopharyngeal head and neck cancers and may preserve voice quality. ..
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    Nguyen N, Frank C, Moltz C, Vos P, Smith H, Bhamidipati P, et al. Aspiration rate following chemoradiation for head and neck cancer: an underreported occurrence. Radiother Oncol. 2006;80:302-6 pubmed
    ..Diagnostic studies such as MBS should be part of future head and neck cancer prospective studies to assess the prevalence of aspiration, and for rehabilitation. ..
  8. Nguyen N, Smith Raymond L, Vinh Hung V, Sloan D, Davis R, Vos P, et al. Feasibility of Tomotherapy to spare the cochlea from excessive radiation in head and neck cancer. Oral Oncol. 2011;47:414-9 pubmed publisher
    ..Helical Tomotherapy for head and neck cancer may significantly decrease radiation dose to the cochlea without sacrificing target volume coverage. ..
  9. Nguyen N, Jang S, Vock J, Vinh Hung V, Chi A, Vos P, et al. Feasibility of intensity-modulated and image-guided radiotherapy for locally advanced esophageal cancer. BMC Cancer. 2014;14:265 pubmed publisher
    ..No patients developed grade 3-4 pneumonitis or cardiac complications. IMRT and IGRT may be effective for the treatment of locally advanced esophageal cancer with acceptable complications. ..

More Information

Publications20

  1. Nguyen N, Vos P, Vinh Hung V, Ceizyk M, Smith Raymond L, Stevie M, et al. Feasibility of image-guided radiotherapy based on helical tomotherapy to reduce contralateral parotid dose in head and neck cancer. BMC Cancer. 2012;12:175 pubmed publisher
    ..3% and 18.2% (p < 0.0001) Tomotherapy for head and neck cancer minimized radiotherapy dose to the contralateral parotid gland in patients undergoing elective node irradiation without sacrificing target coverage. ..
  2. Nguyen N, Ceizyk M, Vos P, Vinh Hung V, Davis R, Desai A, et al. Effectiveness of image-guided radiotherapy for laryngeal sparing in head and neck cancer. Oral Oncol. 2010;46:283-6 pubmed publisher
    ..0001). Laryngeal sparing IGRT technique for head and neck cancer minimizes radiotherapy dose to the larynx and pharynx without sacrificing target coverage, even in the presence of neck lymph nodes. ..
  3. Nguyen N, Ly B, Betz M, Vinh Hung V. Importance of age as a prognostic factor for tonsillar carcinoma. Ann Surg Oncol. 2010;17:2570-7 pubmed publisher
    ..Prospective studies on oropharyngeal cancers should be performed to confirm this hypothesis. ..
  4. Nguyen N, Vock J, Chi A, Ewell L, Vos P, Mills M, et al. Effectiveness of intensity-modulated and image-guided radiotherapy to spare the mandible from excessive radiation. Oral Oncol. 2012;48:653-7 pubmed publisher
    ..Sharp dose falloff associated with IMRT and IGRT decreased excessive radiation of the mandible and may reduce the risks of osteoradionecrosis...
  5. Nguyen N, Chi A, Nguyen L, Ly B, Karlsson U, Vinh Hung V. Human papillomavirus-associated oropharyngeal cancer: a new clinical entity. QJM. 2010;103:229-36 pubmed publisher
    ..A history of oral sex should be elicited in young patients with enlarged neck nodes and/or tonsillar masses. ..
  6. Nguyen N, Frank C, Moltz C, Vos P, Smith H, Nguyen P, et al. Analysis of factors influencing aspiration risk following chemoradiation for oropharyngeal cancer. Br J Radiol. 2009;82:675-80 pubmed publisher
    ..Patients with large tumours had a significant risk of developing aspiration following treatment...
  7. Nguyen N, Vock J, Vinh Hung V, Almeida F, Ewell L, Betz M, et al. Effectiveness of prophylactic retropharyngeal lymph node irradiation in patients with locally advanced head and neck cancer. BMC Cancer. 2012;12:253 pubmed publisher
    ..Prophylactic irradiation of retropharyngeal lymph nodes with IMRT or IGRT provides effective regional control for individuals at risk for recurrence in these nodes. ..
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    Nguyen N, Frank C, Moltz C, Millar C, Vos P, Smith H, et al. Risk of aspiration following radiation for non-nasopharyngeal head and neck cancer. J Otolaryngol Head Neck Surg. 2008;37:225-9 pubmed
    ..We assessed the rate of aspiration following radiation for non-nasopharyngeal head and neck cancer...
  9. Nguyen N, Ceizyk M, Vinh Hung V, Sroka T, Jang S, Khan R, et al. Feasibility of tomotherapy to reduce cochlea radiation dose in patients with locally advanced nasopharyngeal cancer. Tumori. 2012;98:709-14 pubmed publisher
    ..IGRT for head and neck cancer delivered by tomotherapy can significantly decrease the radiation dose to the cochlea without sacrificing target volume coverage. ..
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    Nguyen N, Moltz C, Frank C, Vos P, Millar C, Smith H, et al. Aspiration rate following nonsurgical therapy for laryngeal cancer. ORL J Otorhinolaryngol Relat Spec. 2007;69:116-20 pubmed
    ..Diagnostic studies such as modified barium swallow should be part of future laryngeal cancer prospective studies to assess the prevalence of aspiration as it may be silent...
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    Nguyen N, Moltz C, Frank C, Vos P, Smith H, Nguyen P, et al. Impact of swallowing therapy on aspiration rate following treatment for locally advanced head and neck cancer. Oral Oncol. 2007;43:352-7 pubmed
    ..However, a significant number of patients still suffered from chronic severe aspiration. New strategies must be devised to improve their outcome...