Joanna M Young

Summary

Country: New Zealand

Publications

  1. ncbi Endothelium-ameliorating effects of statin therapy and coenzyme Q10 reductions in chronic heart failure
    Christopher H Strey
    Lipid and Diabetes Research Group, Christchurch Hospital, Christchurch, New Zealand
    Atherosclerosis 179:201-6. 2005
  2. ncbi Pharmacokinetic comparison of a generic coenzyme Q₁₀ solubilizate and a formulation with soybean phytosterols
    Joanna M Young
    Lipid and Diabetes Research Group, Diabetes Research Institute, Christchurch Hospital Campus, Private Bag 4710, Christchurch, New Zealand
    Phytother Res 26:1092-6. 2012
  3. ncbi A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the metabolic syndrome
    Joanna M Young
    Lipid and Diabetes Research Group, Diabetes Research Institute, Christchurch Hospital Campus, New Zealand
    Am J Hypertens 25:261-70. 2012
  4. ncbi Comparative effects of enzogenol and vitamin C supplementation versus vitamin C alone on endothelial function and biochemical markers of oxidative stress and inflammation in chronic smokers
    Joanna M Young
    Lipid and Diabetes Research Group, Christchurch Hospital, New Zealand
    Free Radic Res 40:85-94. 2006
  5. ncbi Effect of coenzyme Q(10) supplementation on simvastatin-induced myalgia
    Joanna M Young
    Lipid and Diabetes Research Group, Christchurch Hospital, Christchurch, New Zealand
    Am J Cardiol 100:1400-3. 2007
  6. ncbi Effect of atorvastatin on plasma levels of asymmetric dimethylarginine in patients with non-ischaemic heart failure
    Joanna M Young
    Lipid and Diabetes Research Group, Christchurch Hospital, Christchurch, New Zealand
    Eur J Heart Fail 10:463-6. 2008
  7. ncbi Relationship between plasma coenzyme Q10, asymmetric dimethylarginine and arterial stiffness in patients with phenotypic or genotypic familial hypercholesterolemia on long-term statin therapy
    Joanna M Young
    Lipid and Diabetes Research Group, Diabetes Research Institute, Christchurch Hospital Campus, Private Bag 4710, Christchurch 8011, New Zealand
    Atherosclerosis 218:188-93. 2011
  8. ncbi Coenzyme Q10; an adjunctive therapy for congestive heart failure?
    Sarah L Molyneux
    Biochemistry Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    N Z Med J 122:74-9. 2009

Collaborators

Detail Information

Publications8

  1. ncbi Endothelium-ameliorating effects of statin therapy and coenzyme Q10 reductions in chronic heart failure
    Christopher H Strey
    Lipid and Diabetes Research Group, Christchurch Hospital, Christchurch, New Zealand
    Atherosclerosis 179:201-6. 2005
    ..Further studies are required to determine whether coenzyme Q(10) reductions are limiting the maximum favourable effects of statin therapy on the microcirculation...
  2. ncbi Pharmacokinetic comparison of a generic coenzyme Q₁₀ solubilizate and a formulation with soybean phytosterols
    Joanna M Young
    Lipid and Diabetes Research Group, Diabetes Research Institute, Christchurch Hospital Campus, Private Bag 4710, Christchurch, New Zealand
    Phytother Res 26:1092-6. 2012
    ..74). The combined CoQ₁₀ and phytosterol formulation, SterolQ₁₀, showed bioequivalence to the generic CoQ₁₀ following a single CoQ₁₀ dose, and demonstrated comparable bioavailability following multiple dose administration...
  3. ncbi A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the metabolic syndrome
    Joanna M Young
    Lipid and Diabetes Research Group, Diabetes Research Institute, Christchurch Hospital Campus, New Zealand
    Am J Hypertens 25:261-70. 2012
    ..Our aim was to examine the effects of adjunctive coenzyme Q(10) therapy on 24-h ambulatory blood pressure (BP) in subjects with the metabolic syndrome and inadequate BP control...
  4. ncbi Comparative effects of enzogenol and vitamin C supplementation versus vitamin C alone on endothelial function and biochemical markers of oxidative stress and inflammation in chronic smokers
    Joanna M Young
    Lipid and Diabetes Research Group, Christchurch Hospital, New Zealand
    Free Radic Res 40:85-94. 2006
    ..However, Enzogenol did demonstrate additional favourable effects on protein oxidative damage and fibrinogen levels...
  5. ncbi Effect of coenzyme Q(10) supplementation on simvastatin-induced myalgia
    Joanna M Young
    Lipid and Diabetes Research Group, Christchurch Hospital, Christchurch, New Zealand
    Am J Cardiol 100:1400-3. 2007
    ..47). In conclusion, coenzyme Q(10) supplementation did not improve statin tolerance or myalgia, although further studies are warranted...
  6. ncbi Effect of atorvastatin on plasma levels of asymmetric dimethylarginine in patients with non-ischaemic heart failure
    Joanna M Young
    Lipid and Diabetes Research Group, Christchurch Hospital, Christchurch, New Zealand
    Eur J Heart Fail 10:463-6. 2008
    ..Since statins upregulate eNOS and ameliorate endothelial dysfunction in non-ischaemic CHF, we hypothesized that this may be in part through modification of ADMA...
  7. ncbi Relationship between plasma coenzyme Q10, asymmetric dimethylarginine and arterial stiffness in patients with phenotypic or genotypic familial hypercholesterolemia on long-term statin therapy
    Joanna M Young
    Lipid and Diabetes Research Group, Diabetes Research Institute, Christchurch Hospital Campus, Private Bag 4710, Christchurch 8011, New Zealand
    Atherosclerosis 218:188-93. 2011
    ....
  8. ncbi Coenzyme Q10; an adjunctive therapy for congestive heart failure?
    Sarah L Molyneux
    Biochemistry Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    N Z Med J 122:74-9. 2009
    ..CoQ10 depletion may also be a contributory factor for why statin intervention has not improved outcomes in CHF. There is an emerging evidence base in support of CoQ10 as an adjunctive therapy in CHF...