B Delahunt

Summary

Affiliation: Wellington School of Medicine
Country: New Zealand

Publications

  1. doi request reprint Gleason scoring: a comparison of classical and modified (international society of urological pathology) criteria using nadir PSA as a clinical end point
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Heath Sciences, University of Otago, Wellington, New Zealand
    Pathology 42:339-43. 2010
  2. doi request reprint A novel grading system for clear cell renal cell carcinoma incorporating tumor necrosis
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand
    Am J Surg Pathol 37:311-22. 2013
  3. doi request reprint Gleason grading: past, present and future
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand
    Histopathology 60:75-86. 2012
  4. ncbi request reprint Progeria kidney has abnormal mesangial collagen distribution
    B Delahunt
    Department of Pathology, Wellington School of Medicine, University of Otago, PO Box 7343, Wellington South, New Zealand
    Pediatr Nephrol 15:279-85. 2000
  5. ncbi request reprint History of the development of the classification of renal cell neoplasia
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, 23A Mein Street, Wellington South, New Zealand
    Clin Lab Med 25:231-46, v. 2005
  6. ncbi request reprint Evolution of the degree Doctor of Medicine at the University of Otago
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences
    N Z Med J 115:135-6. 2002
  7. ncbi request reprint Renal cell neoplasia
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine, New Zealand
    Pathology 34:13-20. 2002
  8. ncbi request reprint Prognostic importance of tumor size for localized conventional (clear cell) renal cell carcinoma: assessment of TNM T1 and T2 tumor categories and comparison with other prognostic parameters
    Brett Delahunt
    Department of Pathology, Wellington School of Medicine, University of Otago, Wellington, New Zealand
    Cancer 94:658-64. 2002
  9. ncbi request reprint Outcome prediction for renal cell carcinoma: evaluation of prognostic factors for tumours divided according to histological subtype
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, Wellington South, New Zealand
    Pathology 39:459-65. 2007
  10. ncbi request reprint Evolving classification of renal cell neoplasia
    B Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, PO Box 7343, Wellington South, New Zealand
    Expert Rev Anticancer Ther 1:576-84. 2001

Collaborators

Detail Information

Publications47

  1. doi request reprint Gleason scoring: a comparison of classical and modified (international society of urological pathology) criteria using nadir PSA as a clinical end point
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Heath Sciences, University of Otago, Wellington, New Zealand
    Pathology 42:339-43. 2010
    ..To compare the distribution and predictive performance of Gleason grade and scores derived using classical and modified (International Society of Urological Pathology) criteria...
  2. doi request reprint A novel grading system for clear cell renal cell carcinoma incorporating tumor necrosis
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand
    Am J Surg Pathol 37:311-22. 2013
    ..We conclude that grading for clear cell RCC should be based on nucleolar prominence and necrosis, that ISUP grading should be used for papillary RCC, and that chromophobe RCC should not be graded...
  3. doi request reprint Gleason grading: past, present and future
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand
    Histopathology 60:75-86. 2012
    ....
  4. ncbi request reprint Progeria kidney has abnormal mesangial collagen distribution
    B Delahunt
    Department of Pathology, Wellington School of Medicine, University of Otago, PO Box 7343, Wellington South, New Zealand
    Pediatr Nephrol 15:279-85. 2000
    ..The distribution of collagen within the mesangium of progeria kidney is evidence in support of the concept that progeria is a primary connective tissue disorder...
  5. ncbi request reprint History of the development of the classification of renal cell neoplasia
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, 23A Mein Street, Wellington South, New Zealand
    Clin Lab Med 25:231-46, v. 2005
    ..This article reviews the history of the development of the classification of renal cell neoplasia...
  6. ncbi request reprint Evolution of the degree Doctor of Medicine at the University of Otago
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences
    N Z Med J 115:135-6. 2002
  7. ncbi request reprint Renal cell neoplasia
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine, New Zealand
    Pathology 34:13-20. 2002
  8. ncbi request reprint Prognostic importance of tumor size for localized conventional (clear cell) renal cell carcinoma: assessment of TNM T1 and T2 tumor categories and comparison with other prognostic parameters
    Brett Delahunt
    Department of Pathology, Wellington School of Medicine, University of Otago, Wellington, New Zealand
    Cancer 94:658-64. 2002
    ..This study investigates the prognostic significance of tumor size in a series of organ-confined clear cell renal cell carcinomas...
  9. ncbi request reprint Outcome prediction for renal cell carcinoma: evaluation of prognostic factors for tumours divided according to histological subtype
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, Wellington South, New Zealand
    Pathology 39:459-65. 2007
    ..Although some of these markers have been shown to be significantly associated with survival, these findings remain to be confirmed in large scale follow-up studies...
  10. ncbi request reprint Evolving classification of renal cell neoplasia
    B Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, PO Box 7343, Wellington South, New Zealand
    Expert Rev Anticancer Ther 1:576-84. 2001
    ..More recently additional varieties of conventional RCC (multilocular cystic RCC), collecting duct carcinoma (medullary renal carcinoma) and papillary RCC (Types 1 and 2), each showing a characteristic morphology, have been recognized...
  11. doi request reprint Advances and controversies in grading and staging of renal cell carcinoma
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, University of Otago Wellington, PO Box 7343, Wellington South, New Zealand
    Mod Pathol 22:S24-36. 2009
    ..Although the current TNM classification does provide useful prognostic information it would appear that further modifications are justified to enhance the predictive value of staging for RCC...
  12. doi request reprint Grading of clear cell renal cell carcinoma should be based on nucleolar prominence
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, University of Otago Wellington, Wellington, New Zealand
    Am J Surg Pathol 35:1134-9. 2011
    ..These findings indicate that worst nucleolar grading alone is a valid grading parameter for clear cell renal cell carcinoma...
  13. ncbi request reprint Fuhrman grading is not appropriate for chromophobe renal cell carcinoma
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, New Zealand
    Am J Surg Pathol 31:957-60. 2007
    ..It is concluded that neither Fuhrman grading, nor any of the components of the Fuhrman grading system, is useful as prognostic indicators for this tumor type...
  14. ncbi request reprint Immunohistochemical evidence for mesothelial origin of paratesticular adenomatoid tumour
    B Delahunt
    Departments of Pathology, Wellington School of Medicine, University of Otago, New Zealand
    Histopathology 36:109-15. 2000
    ..To investigate the histogenesis of paratesticular adenomatoid tumour by use of immunohistochemical markers for a variety of carcinomas and mesothelioma...
  15. ncbi request reprint Sarcomatoid carcinoma of the prostate: progression from adenocarcinoma is associated with p53 over-expression
    B Delahunt
    Department of Pathology, Wellington School of Medicine, University of Otago, New Zealand
    Anticancer Res 19:4279-83. 1999
    ....
  16. ncbi request reprint Sarcomatoid renal carcinoma: the final common dedifferentiation pathway of renal epithelial malignancies
    B Delahunt
    Department of Pathology, Wellington School of Medicine, University of Otago, New Zealand
    Pathology 31:185-90. 1999
    ..Rare cases of osteogenic SRC have been described. The tumor shows marked proliferative activity in growth kinetic studies and is usually associated with a poor patient survival that is best predicted by staging...
  17. ncbi request reprint Morphologic typing of papillary renal cell carcinoma: comparison of growth kinetics and patient survival in 66 cases
    B Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine, University of Otago, Wellington, New Zealand
    Hum Pathol 32:590-5. 2001
    ..001), and Ki-67 index (P =.03) to be independently associated with survival. These results provide evidence of the clinical utility of dividing papillary renal cell carcinomas into 2 types according to histologic characteristics...
  18. ncbi request reprint Smooth muscle cell depletion and collagen types in progeric arteries
    W E Stehbens
    Department of Pathology and Molecular Medicine, Wellington School of Medicine, PO Box 7343, South, Wellington, New Zealand
    Cardiovasc Pathol 10:133-6. 2001
    ....
  19. ncbi request reprint The presence of atypical small acinar proliferation in prostate needle biopsy is predictive of carcinoma on subsequent biopsy
    R C Ouyang
    Department of Surgery, Wellington School of Medicine, University of Otago, New Zealand
    BJU Int 87:70-4. 2001
    ..CONCLUSION: The presence of atypia on initial biopsy is a strong predictor of malignancy in subsequent biopsy specimens...
  20. ncbi request reprint Serum creatine kinase levels parallel the clinical course for rhabdomyomatous Wilms tumor
    B Delahunt
    Dept of Pathology and Molecular Medicine, Wellington School of Medicine, PO Box 7343, Wellington South, New Zealand
    Am J Clin Pathol 116:354-9. 2001
    ..We conclude that these enzymes have clinical usefulness as markers for Wilms tumor showing rhabdomyomatous morphologic features...
  21. ncbi request reprint Oral shark cartilage does not abolish carcinogenesis but delays tumor progression in a murine model
    R Barber
    Department of Pathology and Molecular Medicine, Wellington School of Medicine, P.O. Box 7343, Wellington South, New Zealand
    Anticancer Res 21:1065-9. 2001
    ..The development of papillary and solid tumors was significantly delayed in the test group. CONCLUSIONS: In this tumor model oral shark cartilage delays, but does not abolish, tumor progression...
  22. ncbi request reprint VHL and FHIT locus loss of heterozygosity is common in all renal cancer morphotypes but differs in pattern and prognostic significance
    M Velickovic
    Department of Pathology and Molecular Medicine, Wellington School of Medicine, Wellington, New Zealand
    Cancer Res 61:4815-9. 2001
    ....
  23. ncbi request reprint Assessment of ethnic variation in serum levels of total, complexed and free prostate specific antigen. Comparison of Maori, Pacific Island and New Zealand European populations
    Marion A Gray
    Department of Public Health, Wellington School of Medicine and Health Sciences, PO Box 7343, University of Otago, Wellington South, New Zealand
    Pathology 35:480-3. 2003
    ..To determine whether age-adjusted levels of serum total (tPSA) and complexed (cPSA) prostate specific antigen and the ratio of free to tPSA (%fPSA) differ by ethnic group independent of symptomatic disease...
  24. ncbi request reprint Intragenic PTEN/MMAC1 loss of heterozygosity in conventional (clear-cell) renal cell carcinoma is associated with poor patient prognosis
    Marija Velickovic
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, Newtown, Wellington, New Zealand
    Mod Pathol 15:479-85. 2002
    ..Biallelic inactivation may preferentially occur by nonmutational mechanisms, or, alternatively, haploinsufficiency of PTEN/MMAC1 may be sufficient to affect tumor progression in cRCC...
  25. ncbi request reprint Demographic and clinical factors as determinants of serum levels of prostate specific antigen and its derivatives
    Marion A Gray
    Department of Public Health, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand
    Anticancer Res 24:2069-72. 2004
    ....
  26. ncbi request reprint Renal dysplasia produced by obstructive uropathy in the fetal lamb
    Kevin C Pringle
    Department of Surgery and Anaesthesia, Wellington School of Medicine and Health Sciences, University of Otago, PO Box 7343, Wellington South, New Zealand
    Pathology 35:518-21. 2003
    ..It was also undertaken to determine if urinary tract obstruction proximal or distal to the urinary bladder would result in varying renal morphology...
  27. doi request reprint Parameters of perineural invasion in radical prostatectomy specimens lack prognostic significance
    A David Merrilees
    Department of Urology, Wellington Hospital, Wellington, New Zealand
    Mod Pathol 21:1095-100. 2008
    ..We conclude that the investigated parameters of perineural invasion do not predict prostate-specific antigen recurrence in radical prostatectomy specimens...
  28. ncbi request reprint Nucleolar grade but not Fuhrman grade is applicable to papillary renal cell carcinoma
    Dianne Sika-Paotonu
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, Wellington, New Zealand
    Am J Surg Pathol 30:1091-6. 2006
    ....
  29. ncbi request reprint Prostate carcinoma and the Lambert-Eaton myasthenic syndrome
    B Delahunt
    Department of Pathology, Wellington School of Medicine and Health Sciences, Wellington, New Zealand
    J Urol 169:278-9. 2003
  30. ncbi request reprint Prostate cancer screening in Australasia
    D S Lamb
    Wellington Cancer Centre, Wellington Hospital, Wellington, New Zealand
    Clin Oncol (R Coll Radiol) 17:231-3. 2005
  31. ncbi request reprint The histopathology of endocardial sclerosis
    W E Stehbens
    Departments of Pathology and Molecular Medicine and Obstetrics and Gynaecology, Wellington South, New Zealand
    Cardiovasc Pathol 9:161-73. 2000
    ....
  32. ncbi request reprint Prostate cancer--are ethnic minorities disadvantaged?
    David S Lamb
    Department of Pathology and Molecular Medicine, University of Otago Wellington, P O Box 7343, Wellington 6242, New Zealand
    Anticancer Res 28:3891-5. 2008
    ....
  33. ncbi request reprint Chromosome 14q LOH in localized clear cell renal cell carcinoma
    Kenji Mitsumori
    Department of Biochemistry, University of Otago, Dunedin, New Zealand
    J Pathol 198:110-4. 2002
    ....
  34. pmc Reproducibility of new classification schemes for the pathology of ductal carcinoma in situ of the breast
    P Bethwaite
    Department of Pathology, Wellington School of Medicine, New Zealand
    J Clin Pathol 51:450-4. 1998
    ..To compare the interobserver variation in the pathological classification of ductal carcinoma in situ of the breast using two recently proposed classification schemes...
  35. doi request reprint Most multifocal papillary thyroid carcinomas acquire genetic and morphotype diversity through subclonal evolution following the intra-glandular spread of the initial neoplastic clone
    L Jovanovic
    Department of Pathology and Molecular Medicine, University of Otago, School of Medicine and Health Sciences, Wellington, New Zealand
    J Pathol 215:145-54. 2008
    ..In monoclonal BRAF V600E-positive mPTCs, BRAF V600E is not always present in all tumour foci, indicating that other tumour-genetic factors in the primary progenitor clone can also trigger PTC neoplastic transformation...
  36. ncbi request reprint The evolution of collagen expression in sarcomatoid renal cell carcinoma
    Brett Delahunt
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, PO Box 7343, Wellington South, New Zealand
    Hum Pathol 38:1372-7. 2007
    ....
  37. ncbi request reprint Prostate cancer: the new evidence base for diagnosis and treatment
    David S Lamb
    Department of Pathology and Molecular Medicine, Wellington School of Medicine and Health Sciences, and Department of Radiation Oncology, Wellington Hospital, New Zealand
    Pathology 39:537-44. 2007
    ..These improvements mean that now most men aged 50-70 years diagnosed with PC will have clinically significant cancers that require treatment...
  38. ncbi request reprint Vasectomy and risk of prostate cancer
    Brian Cox
    Hugh Adam Cancer Epidemiology Unit, Department of Preventive and Social Medicine, University of Otago Medical School, PO Box 913, Dunedin, New Zealand
    JAMA 287:3110-5. 2002
    ..Vasectomy is a common method of contraception, but concern exists about a reported association with risk of prostate cancer...
  39. ncbi request reprint Expanding the histologic spectrum of mucinous tubular and spindle cell carcinoma of the kidney
    Samson W Fine
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Am J Surg Pathol 30:1554-60. 2006
    ..Pathologists must be aware of the spectrum of histologic findings within MTSCs to ensure their accurate diagnosis...
  40. ncbi request reprint Molecular genetic evidence for the independent origin of multifocal papillary tumors in patients with papillary renal cell carcinomas
    Timothy D Jones
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Clin Cancer Res 11:7226-33. 2005
    ..Molecular analysis of microsatellite and chromosome alterations and X-chromosome inactivation status in separate tumors in the same patient can be used to study the genetic relationships among the coexisting multiple tumors...
  41. ncbi request reprint Chromosomal gains in the sarcomatoid transformation of chromophobe renal cell carcinoma
    Matteo Brunelli
    Anatomia Patologica, Dipartimento di Patologia, Universita di Verona, Verona, Italy
    Mod Pathol 20:303-9. 2007
    ....
  42. ncbi request reprint Few FH mutations in sporadic counterparts of tumor types observed in hereditary leiomyomatosis and renal cell cancer families
    Maija Kiuru
    Department of Medical Genetics, Biomedicum Helsinki or Haartman Institute, University of Helsinki, FIN 00014 Helsinki, Finland
    Cancer Res 62:4554-7. 2002
    ..Whereas the two former lesions were shown to originate from a germ-line mutation, the soft tissue sarcoma is to our knowledge the first example of purely somatic inactivation of FH in tumors...
  43. ncbi request reprint Screening for prostate cancer: a response to four letters
    David Lamb
    N Z Med J 118:U1390. 2005
  44. ncbi request reprint Prostate cancer screening--finding the middle road forward
    David S Lamb
    N Z Med J 118:U1306. 2005
  45. ncbi request reprint Eosinophilic and classic chromophobe renal cell carcinomas have similar frequent losses of multiple chromosomes from among chromosomes 1, 2, 6, 10, and 17, and this pattern of genetic abnormality is not present in renal oncocytoma
    Matteo Brunelli
    Department of Pathology and Laboratory Medicine, Universita di Verona, Verona, Italy
    Mod Pathol 18:161-9. 2005
    ....
  46. ncbi request reprint Editorial: Genitourinary pathology 120 years on
    Brett Delahunt
    Pathology 35:465-6. 2003
  47. ncbi request reprint Renal mucinous tubular and spindle carcinoma lacks the gains of chromosomes 7 and 17 and losses of chromosome Y that are prevalent in papillary renal cell carcinoma
    Paolo Cossu-Rocca
    Department of Pathology, Indiana University Medical Center, University Hospital, Indianapolis, IN 46202, USA
    Mod Pathol 19:488-93. 2006
    ..FISH analysis with centromeric probes for these chromosomes is potentially helpful in differentiating mucinous tubular and spindle cell carcinomas from papillary renal cell carcinomas...