Research Topics
| Julian CraneSummaryAffiliation: Wellington School of Medicine Country: New Zealand Publications
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Publications
Agreement between written and video questions for comparing asthma symptoms in ISAACJ Crane
Wellington Asthma Research Group, Dept of Medicine, School of Medicine, Wellington, New Zealand
Eur Respir J 21:455-61. 2003..This relationship and the interpretation of both written and audiovisual presentation of symptoms requires further study in order to better predict asthma...
Pro and anti: the biotics of allergic diseaseJ Crane
Wellington Asthma Research Group, School of Medicine and Health Sciences, New Zealand
Thorax 57:II40-II46. 2002- Asthma and allergic diseases: is there a downside to cleanliness and can we exploit it?J Crane
Department of Medicine, Wellington School of Medicine and Health Science, PO Box 7343, Wellington, New Zealand
Eur J Clin Nutr 56:S39-43. 2002..The challenge is to continue to reap the enormous benefits that accrued from modifying infectious disease by both public and individual health strategies but at the same time convincing the immune system that it has been exposed to them... - Time for major roadworks on the tobacco road?Julian Crane
Department of Medicine, Wellington School of Medicine, University of Otago, Wellington, New Zealand
N Z Med J 117:U801. 2004 
Breastfeeding protects against adverse respiratory outcomes at 15 months of ageKaren M Silvers
Department of Medicine, University of Otago, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
Matern Child Nutr 5:243-50. 2009..In conclusion, there was a significant protective effect of breastfeeding on infant wheezing and other adverse respiratory outcomes that may be early indicators of asthma in New Zealand children...- Asthma, atopy and exhaled nitric oxide in a cohort of 6-yr-old New Zealand childrenJulian Crane
Wellington Asthma Research Group, Department of Medicine, University of Otago, Wellington, New Zealand
Pediatr Allergy Immunol 23:59-64. 2012..Exhaled nitric oxide has been promoted as a non-invasive measure of airway inflammation, with clinical utility for the diagnosis and management of asthma... - Breastfeeding protects against current asthma up to 6 years of ageKaren M Silvers
Department of Paediatrics, School of Medicine and Health Sciences, University of Otago Christchurch, Christchurch, New Zealand
J Pediatr 160:991-6.e1. 2012..To investigate the effects of breastfeeding on wheezing and current asthma in children 2 to 6 years of age... - A measure for quantifying the impact of housing quality on respiratory health: a cross-sectional studyMichael D Keall
He Kainga Oranga Housing and Health Research Programme, Department of Public Health, University of Otago, PO Box 7343, Wellington South, New Zealand
Environ Health 11:33. 2012..Damp and mould in homes have been established as risk factors for respiratory health. There is a need for a relatively straightforward assessment of the home that quantifies this risk... - Endotoxin exposure, wheezing, and rash in infancy in a New Zealand birth cohortJulie Gillespie
Wellington Asthma Research Group, Department of Medicine, Wellington South, New Zealand
J Allergy Clin Immunol 118:1265-70. 2006..Recently, increased levels of endotoxin in the domestic environment have also been associated with infant wheezing, particularly among infants with a family history of atopic disease... - Endotoxin, (1 --> 3)-beta-D-glucans and fungal extra-cellular polysaccharides in New Zealand homes: a pilot studyJeroen Douwes
Centre for Public Health Research, Research School of Public Health, Massey University, Wellington, New Zealand, Private Box 756, Wellington, New Zealand
Ann Agric Environ Med 13:361-5. 2006..In conclusion, levels of microbial contaminants in a small random sample of New Zealand homes were high and weakly associated with water damage... - The New Zealand Asthma and Allergy Cohort Study (NZA2CS): assembly, demographics and investigationsMichael J Epton
Canterbury Respiratory Research Group, Department of Medicine, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
BMC Public Health 7:26. 2007..This paper describes the establishment of a birth cohort in New Zealand... - Randomized crossover trial of the acceptability of snus, nicotine gum, and Zonnic therapy for smoking reduction in heavy smokersBrent Caldwell
Department of Medicine, University of Otago, PO Box 7343, Wellington, New Zealand
Nicotine Tob Res 12:179-83. 2010.... - Effects of improved home heating on asthma in community dwelling children: randomised controlled trialPhilippa Howden-Chapman
He Kainga Oranga Housing and Health Research Programme, University of Otago, Wellington, PO 7343, Wellington South, New Zealand
BMJ 337:a1411. 2008..To assess whether non-polluting, more effective home heating (heat pump, wood pellet burner, flued gas) has a positive effect on the health of children with asthma... - A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trialKristin Wickens
Wellington Asthma Research Group, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand
J Allergy Clin Immunol 122:788-94. 2008..The role of probiotics in prevention of allergic disease is still not clearly established, although early reports suggested Lactobacillus GG halved the risk of eczema at 2 years... - Effect of insulating existing houses on health inequality: cluster randomised study in the communityPhilippa Howden Chapman
He Kainga Oranga, Housing and Health Research Programme, University of Otago, Wellington, PO Box 7343, Wellington South, New Zealand
BMJ 334:460. 2007..To determine whether insulating existing houses increases indoor temperatures and improves occupants' health and wellbeing... - Prevalence of mouse allergen (Mus m 1) in homes of New Zealand rural childrenSue Peters
Wellington Asthma Research Group, Wellington School of Medicine and Health Sciences, Wellington, New Zealand
Asian Pac J Allergy Immunol 24:81-4. 2006..No significant associations were found between Mus m 1 levels and atopic status or allergic diseases. Mouse allergen is unlikely to be an important indoor allergen for rural New Zealand children... - Beta-(1,3)-glucan levels and its determinants in New Zealand bedroomsJennifer Heyes
Wellington Asthma Research Group, University of Otago, Wellington, New Zealand
J Asthma 46:64-6. 2009..2-146.4) from pillows. Synthetic bedding and older mattresses contained higher beta-(1,3)-glucan levels. Synthetic bedding contains higher levels of beta-(1,3)-glucan than feather bedding, which may be of importance to asthmatics... - A pilot study of nicotine delivery to smokers from a metered-dose inhalerBrent Caldwell
Department of Medicine, School of Medicine and Health Sciences, University of Otago, Wellington, Wellington South, New Zealand
Nicotine Tob Res 11:342-7. 2009..The present study generated preliminary data on the acceptability and pharmacokinetics of nicotine administered by a simple metered-dose inhaler (MDI)... - Upper body clothing is a source of fungal beta-(1,3)-glucan exposureRobert Siebers
Wellington Asthma Research Group, School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand
J Asthma 44:649-50. 2007..Beta-(1,3)-glucan levels were significantly lower from cotton jerseys and from warm water washed jerseys. Thus, jerseys are potentially a significant exposure source of beta-(1,3)-glucan... - Improving health and energy efficiency through community-based housing interventionsPhilippa Howden-Chapman
He Kainga Oranga Housing and Health Research Programme, University of Otago, Wellington, New Zealand
Int J Public Health 56:583-8. 2011..Our aim is to find cost-effective ways to improve the characteristics of older homes, ill-fitted for New Zealand's climate, in order to improve the occupants' health... - Measurement of exhaled nitric oxide in a general population sample: a comparison of the Medisoft HypAir FE(NO) and Aerocrine NIOX analyzersCollin R Brooks
Centre for Public Health Research, Massey University, Wellington, New Zealand
J Asthma 48:324-8. 2011.... - Asthma prevalence in European, Maori, and Pacific children in New Zealand: ISAAC studyPhilip K Pattemore
Department of Paediatrics, Christchurch School of Medicine and Health Sciences, University of Otago, Otago, New Zealand
Pediatr Pulmonol 37:433-42. 2004..Further studies are needed to determine the reasons for these apparent differences in asthma severity... - Rethinking the regulatory framework for tobacco control in New ZealandGeorge Thomson
Department of Public Health, Wellington School of Medicine and Health Sciences, University of Otago, Wellington South, New Zealand
N Z Med J 118:U1405. 2005..As the authority could be funded through levies on the tobacco industry, it has the potential advantage of delivering major population health gains while costing the taxpayer nothing... - Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programmeRichard Beasley
Medical Research Institute of New Zealand, Wellington, New Zealand
Lancet 372:1039-48. 2008..We studied 6-7-year-old children from Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC) programme to investigate the association between paracetamol consumption and asthma... - Smoking cessation is a prolonged journey rather than a single tripK Marie Ditchburn
Department of Medicine, University of Otago, Wellington, PO Box 7343, Wellington, New Zealand
N Z Med J 125:91-7. 2012..This viewpoint outlines the reasons why New Zealand can ill afford not to have nationwide specialist smoking-cessation clinics... - A systematic review of nicotine by inhalation: is there a role for the inhaled route?Brent Caldwell
Department of Medicine, University of Otago, 23A Mein Street, Newtown, Wellington 6021, New Zealand
Nicotine Tob Res 14:1127-39. 2012..This review draws together what is currently known about pulmonary nicotine delivery and identifies potential ways that deep lung delivery can be achieved with a simple portable device... - The determinants of dust mite allergen and its relationship to the prevalence of symptoms of asthma in the Asia-Pacific regionKristin Wickens
Department of Medicine, Wellington Asthma Research Group, Wellington School of Medicine and Health Sciences, University of Otago, PO Box 7343, Wellington South, New Zealand
Pediatr Allergy Immunol 15:55-61. 2004..While our findings suggest that Dermatophagoides pteronyssinus may have a role in the primary causation of asthma, the complexity of this association reinforces the need for prospective studies... - International trends in asthma mortality rates in the 5- to 34-year age group: a call for closer surveillanceMeme Wijesinghe
Medical Research Institute of New Zealand, Wellington, New Zealand
Chest 135:1045-9. 2009..Since then, little attention has been paid to the ongoing international time trends... - Bifidobacterial species differentially affect expression of cell surface markers and cytokines of dendritic cells harvested from cord bloodSarah L Young
Department of Microbiology, University of Otago, Dunedin, New Zealand
Clin Diagn Lab Immunol 11:686-90. 2004..bifidum, B. longum, and B. pseudocatenulatum induce a Th2-driven immune response. A hypothesis is presented to link our observations to the prevalence of atopic diseases in different countries... - Clothing--potentially a significant source of endotoxin exposureHae-Seon Nam
J Allergy Clin Immunol 112:624-5. 2003 - Endotoxin and house dust mite allergen levels on synthetic and buckwheat pillowsHae-Seon Nam
Genome Research Center for Allergy and Respiratory Diseases, Soonchunhyang University, Bucheon, Korea
J Korean Med Sci 19:505-8. 2004..16 microg/g (0.02-8.13) and 1.08 microg/g (0.19-1.68) respectively. These results indicate that buckwheat pillows are a source of very high endotoxin levels that may be of relevance to asthma severity of atopic asthmatics... - Cat and dust mite sensitivity and tolerance in relation to wheezing among children raised with high exposure to both allergensElizabeth A Erwin
University of Virginia Asthma and Allergic Diseases Center, Charlottesville, VA 22908, USA
J Allergy Clin Immunol 115:74-9. 2005..The strength of the IgE antibody response to dust mite in humid climates could contribute to the increased prevalence and severity of asthma... - Quantitative measurement of IgE antibodies to purified allergens using streptavidin linked to a high-capacity solid phaseElizabeth A Erwin
University of Virginia Astma and Allergic Diseases Center, Charlottesville, VA 22908-1355, USA
J Allergy Clin Immunol 115:1029-35. 2005..In addition, the results demonstrate major differences in IgE antibodies specific for mite and cat allergens among children with high exposure to both allergens... - Long-acting beta agonists--prescribe with careJulian Crane
N Z Med J 119:U2064. 2006 - Occupational respiratory health of New Zealand horse trainersLou M Gallagher
Institute for Environmental Science and Research, Kenepuru, New Zealand
Int Arch Occup Environ Health 80:335-41. 2007..To confirm that working with horses is an occupational respiratory hazard and observed associations are not attributable to confounding... - Contribution of dust mite and cat specific IgE to total IgE: relevance to asthma prevalenceElizabeth A Erwin
University of Virginia Asthma and Allergic Diseases Center, Charlottesville, VA, USA
J Allergy Clin Immunol 119:359-65. 2007..The prevalence of asthma is strikingly different in some Westernized countries: approximately 20% in New Zealand and approximately 8% in northern Sweden... - Has the prevalence and severity of symptoms of asthma changed among children in New Zealand? ISAAC Phase ThreeM Innes Asher
Department of Paediatrics Child and Youth Health, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland Mail Centre, Auckland 1142, New Zealand
N Z Med J 121:52-63. 2008..To investigate time trends in prevalence of symptoms of asthma by repeating, during 2001-3 (Phase Three), the International Study of Asthma and Allergies in Childhood (ISAAC) Phase One study that was conducted in New Zealand in 1992-3... - To skin prick test or not to skin prick test - this is the questionIsobel R Martin
Department of General Practice, Dunedin School of Medicine, Dunedin
N Z Med J 115:U166. 2002 - Endotoxin from synthetic and feather pillowsKaren Hall
J Allergy Clin Immunol 110:811. 2002 - House dust mite allergen levels in individual bedding components in New ZealandSarah Mills
Department of Public Health, Wellington School of Medicine and Health Sciences
N Z Med J 115:151-3. 2002..CONCLUSIONS: Synthetic pillows and duvets contain higher levels of Der p 1 than feather pillows and duvets. Advise for house dust mite sensitized individuals to use synthetic bedding does not prevent house dust mite allergen exposure... - Asthma prevalence: mysterious enigmatic riddle or time-expired illusion? Can we solve a riddle by burying an illusion?Julian Crane
Med J Aust 180:263-4. 2004 - A comparison of two skin test methodologies and allergens from two different manufacturersRobert Rhodius
Faculty of Medicine, University of Groningen, The Netherlands
Ann Allergy Asthma Immunol 88:374-9. 2002..There were similar differences between methods of application for reactions measured as an area. CONCLUSIONS: SPTs that use different allergens or different methods of application will not provide comparable assessments of atopy... - Inhaled corticosteroids in asthma action plans--double or quits?Julian Crane
N Z Med J 117:U930. 2004 - House dust mite allergens in domestic homes in Cheonan, KoreaHae Seon Nam
Department of Clinical Parasitology, School of Medicine, Soonchunhyang University, Cheonan 330 090, Korea
Korean J Parasitol 46:187-9. 2008..Corresponding levels of Der f 1 were higher, 7.46 microgram/g (range: 0.01-262.9) and 10.2 microgram/g (range: 0.01-230.9) for floors and mattresses, respectively. D. farinae appears to be the dominant house dust mite in Cheonan... - Child-care center sandpits: a source of cat allergen (Fel d 1)Rob Siebers
J Allergy Clin Immunol 118:533-4. 2006 - Activated charcoal suppresses breeding of the house dust mite, Dermatophagoides pteronyssinus, in cultureHae Seon Nam
Department of Clinical Parasitology and Allergy, Soonchunghyang University, Cheonan, Korea
J Korean Med Sci 22:383-5. 2007..Thus, activated charcoal suppresses breeding of house dust mites and offers a new promising method for house dust mite control... - Salamol and asthma in New ZealandD Robin Taylor
N Z Med J 119:U2328; author reply U2328; discussion U2328. 2006 - Endotoxin and indoor allergen levels in kindergartens and daycare centres in Wellington, New ZealandKaren Oldfield
Wellington Asthma Research Group, Wellington School of Medicine and Health Sciences, Wellington South
N Z Med J 120:U2400. 2007..The purpose of this study was to measure endotoxin and indoor allergens in kindergartens and daycare centres in the Wellington region...