Gerald W Tannock

Summary

Affiliation: University of Otago
Country: New Zealand

Publications

  1. pmc Comparison of the compositions of the stool microbiotas of infants fed goat milk formula, cow milk-based formula, or breast milk
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 79:3040-8. 2013
  2. doi request reprint Comprehensive analysis of the bacterial content of stool from patients with chronic pouchitis, normal pouches, or familial adenomatous polyposis pouches
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Inflamm Bowel Dis 18:925-34. 2012
  3. doi request reprint A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficile-infected patients than does vancomycin
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Microbiology 156:3354-9. 2010
  4. doi request reprint Bowel microbiota moderate host physiological responses to dietary konjac in weanling rats
    Wayne Young
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    J Nutr 143:1052-60. 2013
  5. pmc Resource partitioning in relation to cohabitation of Lactobacillus species in the mouse forestomach
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    ISME J 6:927-38. 2012
  6. doi request reprint Nucleic acid-based methods to assess the composition and function of the bowel microbiota
    Blair Lawley
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Gastroenterol Clin North Am 41:855-68. 2012
  7. ncbi request reprint The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients
    Rodrigo Bibiloni
    Department of Agricultural, Food and Nutritional Science, University of Otago, PO Box 56, Dunedin, New Zealand
    J Med Microbiol 55:1141-9. 2006
  8. pmc Changes in bowel microbiota induced by feeding weanlings resistant starch stimulate transcriptomic and physiological responses
    Wayne Young
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 78:6656-64. 2012
  9. ncbi request reprint D-alanyl ester depletion of teichoic acids in Lactobacillus reuteri 100-23 results in impaired colonization of the mouse gastrointestinal tract
    Jens Walter
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Environ Microbiol 9:1750-60. 2007
  10. doi request reprint Glucosyltransferase A (GtfA) and inulosucrase (Inu) of Lactobacillus reuteri TMW1.106 contribute to cell aggregation, in vitro biofilm formation, and colonization of the mouse gastrointestinal tract
    Jens Walter
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Microbiology 154:72-80. 2008

Collaborators

Detail Information

Publications33

  1. pmc Comparison of the compositions of the stool microbiotas of infants fed goat milk formula, cow milk-based formula, or breast milk
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 79:3040-8. 2013
    ..When Bifidobacteriaceae abundance was low, Lachnospiraceae abundances were greater. New information about the composition of the fecal microbiota when goat milk formula is used in infant nutrition was thus obtained...
  2. doi request reprint Comprehensive analysis of the bacterial content of stool from patients with chronic pouchitis, normal pouches, or familial adenomatous polyposis pouches
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Inflamm Bowel Dis 18:925-34. 2012
    ..Antibiotic administration reduces symptoms of pouchitis, indicating that bacteria have a role in pathogenesis. The aim of the research was to investigate the bacterial content of pouches using nucleic acid-based methods...
  3. doi request reprint A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficile-infected patients than does vancomycin
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Microbiology 156:3354-9. 2010
    ..These findings help to explain the substantially reduced rates of relapse following treatment of CDI with fidaxomicin in recent clinical trials...
  4. doi request reprint Bowel microbiota moderate host physiological responses to dietary konjac in weanling rats
    Wayne Young
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    J Nutr 143:1052-60. 2013
    ..This response was reduced by the presence of the bowel microbiota, which therefore ameliorated potentially detrimental effects of dietary KJ. ..
  5. pmc Resource partitioning in relation to cohabitation of Lactobacillus species in the mouse forestomach
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    ISME J 6:927-38. 2012
    ..This real life, trophic phenomenon conforms to a mathematical model based on in vitro bacterial doubling times, in vitro transport rates, and concentrations of maltose and glucose in mouse stomach digesta...
  6. doi request reprint Nucleic acid-based methods to assess the composition and function of the bowel microbiota
    Blair Lawley
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Gastroenterol Clin North Am 41:855-68. 2012
    ..Reliance on a single methodology per human study is not recommended. Generally, a study could commence with a screening of samples to determine whether it will be worthwhile expending further time and money on an in-depth analysis...
  7. ncbi request reprint The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients
    Rodrigo Bibiloni
    Department of Agricultural, Food and Nutritional Science, University of Otago, PO Box 56, Dunedin, New Zealand
    J Med Microbiol 55:1141-9. 2006
    ..The observations made in this study should permit targeting of specific bacteriological abnormalities in investigations of the pathogenesis of inflammatory bowel diseases and provide targets for medical interventions...
  8. pmc Changes in bowel microbiota induced by feeding weanlings resistant starch stimulate transcriptomic and physiological responses
    Wayne Young
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 78:6656-64. 2012
    ..Altered transcriptomic and physiological responses may reflect the young host's attempts to maintain homeostasis as a consequence of exposure to a new collection of bacteria and their associated biochemistry...
  9. ncbi request reprint D-alanyl ester depletion of teichoic acids in Lactobacillus reuteri 100-23 results in impaired colonization of the mouse gastrointestinal tract
    Jens Walter
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Environ Microbiol 9:1750-60. 2007
    ..This study showed that D-alanylation is an important cell function of L. reuteri that seems to protect this commensal organism against the hostile conditions prevailing in the murine forestomach...
  10. doi request reprint Glucosyltransferase A (GtfA) and inulosucrase (Inu) of Lactobacillus reuteri TMW1.106 contribute to cell aggregation, in vitro biofilm formation, and colonization of the mouse gastrointestinal tract
    Jens Walter
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Microbiology 154:72-80. 2008
    ..From the evidence provided in this study we conclude that GtfA and Inu confer important ecological attributes of L. reuteri TMW1.106 and contribute to colonization of the mouse gastrointestinal tract...
  11. pmc Impact of consumption of oligosaccharide-containing biscuits on the fecal microbiota of humans
    Gerald W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 70:2129-36. 2004
    ..Our observations suggest that a phylogenetic approach to analysis of the gut ecosystem may not always be optimal and that a more physiological (biochemical) method might be more informative...
  12. pmc Ecological behavior of Lactobacillus reuteri 100-23 is affected by mutation of the luxS gene
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 71:8419-25. 2005
    ..These results demonstrate that LuxS influences important ecological attributes of L. reuteri 100-23C, the consequences of which are niche specific...
  13. doi request reprint A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial
    Kristin Wickens
    Wellington Asthma Research Group, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand
    J Allergy Clin Immunol 122:788-94. 2008
    ..The role of probiotics in prevention of allergic disease is still not clearly established, although early reports suggested Lactobacillus GG halved the risk of eczema at 2 years...
  14. doi request reprint Testing probiotic strain Escherichia coli Nissle 1917 (Mutaflor) for its ability to reduce carriage of multidrug-resistant E. coli by elderly residents in long-term care facilities
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    J Med Microbiol 60:366-70. 2011
    ..Genotyping of norfloxacin-resistant E. coli isolates showed that 32 strains were prevalent among the patients. Thus, E. coli Nissle 1917 does not have the capacity to compete effectively with MDREC in the bowel of elderly patients...
  15. ncbi request reprint What immunologists should know about bacterial communities of the human bowel
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, P O Box 56, 720 Cumberland Street, Dunedin, New Zealand
    Semin Immunol 19:94-105. 2007
    ..The role of the bacterial community in the development and regulation of the immune system of neonates seems likely to be a particularly important area of future research...
  16. pmc Whole-transcriptome shotgun sequencing (RNA-seq) screen reveals upregulation of cellobiose and motility operons of Lactobacillus ruminis L5 during growth on tetrasaccharides derived from barley β-glucan
    Blair Lawley
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 79:5661-9. 2013
    ..indicating that cross feeding of tetrasaccharide between bacteria could occur. Therefore, the RNA-seq screen and subsequent experiments had utility in revealing foraging attributes of gut commensal Lactobacillus ruminis...
  17. pmc RNA-stable-isotope probing shows utilization of carbon from inulin by specific bacterial populations in the rat large bowel
    Gerald W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 80:2240-7. 2014
    ..Thus, RNA-stable-isotope probing (RNA-SIP) provided new information about the use of carbon from inulin in microbiota metabolism. ..
  18. pmc A special fondness for lactobacilli
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 70:3189-94. 2004
  19. ncbi request reprint The search for disease-associated compositional shifts in bowel bacterial communities of humans
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, 9054, New Zealand
    Trends Microbiol 16:488-95. 2008
    ..Therefore, important challenges remain for bacteriologists in investigations of the bowel bacterial community in relation to disease...
  20. doi request reprint Gut commensal Lactobacillus reuteri 100-23 stimulates an immunoregulatory response
    Megan Livingston
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Immunol Cell Biol 88:99-102. 2010
    ..reuteri 100-23 stimulated the development of an increased number of regulatory T cells...
  21. pmc Bifidobacterial species differentially affect expression of cell surface markers and cytokines of dendritic cells harvested from cord blood
    Sarah L Young
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Clin Diagn Lab Immunol 11:686-90. 2004
    ..bifidum, B. longum, and B. pseudocatenulatum induce a Th2-driven immune response. A hypothesis is presented to link our observations to the prevalence of atopic diseases in different countries...
  22. doi request reprint The immune response to autologous bacteroides in ankylosing spondylitis is characterized by reduced interleukin 10 production
    Simon M Stebbings
    Department of Medicine, University of Otago School of Medicine, PO Box 913, Dunedin 9054, New Zealand
    J Rheumatol 36:797-800. 2009
    ..In order to investigate the host immune response in AS, we measured cytokines in tissue culture following exposure of peripheral blood mononuclear cells (PBMC) to autologous colonic bacteria...
  23. pmc Altered Transcription of Murine Genes Induced in the Small Bowel by Administration of Probiotic Strain Lactobacillus rhamnosus HN001
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 80:2851-9. 2014
    ..Overall, the results provide links between a probiotic strain, mucosal gene expression, and host phenotype, which may be useful in delineating mechanisms of probiotic action. ..
  24. ncbi request reprint Exploring the relationships between intestinal microflora and inflammatory conditions of the human bowel and spine
    Gerald W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Antonie Van Leeuwenhoek 81:529-35. 2002
  25. pmc Transcriptional and metabolomic consequences of LuxS inactivation reveal a metabolic rather than quorum-sensing role for LuxS in Lactobacillus reuteri 100-23
    Charlotte M Wilson
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    J Bacteriol 194:1743-6. 2012
    ..Cell density-dependent changes (log phase versus stationary phase growth) in gene transcription were not detected, indicating that AI-2 was unlikely to be involved in gene regulation mediated by quorum sensing in L. reuteri 100-23...
  26. ncbi request reprint Probiotics: time for a dose of realism
    Gerald W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Curr Issues Intest Microbiol 4:33-42. 2003
    ..These new products, however, will need to be targeted at the alleviation of specific medical conditions, and the mechanistic basis of their effectiveness will need to be provided...
  27. ncbi request reprint Commentary: Remembrance of microbes past
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Int J Epidemiol 34:13-5. 2005
  28. pmc A high-molecular-mass surface protein (Lsp) and methionine sulfoxide reductase B (MsrB) contribute to the ecological performance of Lactobacillus reuteri in the murine gut
    Jens Walter
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 71:979-86. 2005
    ..Homologues of lsp and msrB are present in the genomes of several strains of Lactobacillus and may play an important role in the maintenance of these bacteria in gut ecosystems...
  29. pmc Construction, analysis, and beta-glucanase screening of a bacterial artificial chromosome library from the large-bowel microbiota of mice
    Jens Walter
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 71:2347-54. 2005
    ....
  30. ncbi request reprint New perceptions of the gut microbiota: implications for future research
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, 720 Cumberland Street, PO Box 56, Dunedin, New Zealand
    Gastroenterol Clin North Am 34:361-82, vii. 2005
  31. pmc Epidemiology, relative invasive ability, molecular characterization, and competitive performance of Campylobacter jejuni strains in the chicken gut
    Christopher Pope
    Department of Microbiology and Immunology, University of Otago, P O Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 73:7959-66. 2007
    ..jejuni, that some Campylobacter strains detected in poultry meat are of higher virulence for humans than others, and that bacterial attributes affecting strain virulence and commensal colonization ability may be linked...
  32. ncbi request reprint The bifidobacterial and Lactobacillus microflora of humans
    Gerald W Tannock
    Department of Microbiology, University of Otago, PO Box 56, Dunedin, New Zealand
    Clin Rev Allergy Immunol 22:231-53. 2002
  33. pmc Identification, detection, and enumeration of human bifidobacterium species by PCR targeting the transaldolase gene
    Teresa Requena
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 68:2420-7. 2002
    ..In the case of samples from infants, 16S rDNA-targeted PCR was superior to PCR targeting the transaldolase gene for the quantification of bifidobacterial populations...