G W Tannock

Summary

Affiliation: University of Otago
Country: New Zealand

Publications

  1. pmc Resource partitioning in relation to cohabitation of Lactobacillus species in the mouse forestomach
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    ISME J 6:927-38. 2012
  2. ncbi request reprint Probiotic properties of lactic-acid bacteria: plenty of scope for fundamental R & D
    G W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Trends Biotechnol 15:270-4. 1997
  3. ncbi request reprint Probiotics: time for a dose of realism
    Gerald W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Curr Issues Intest Microbiol 4:33-42. 2003
  4. doi request reprint The search for disease-associated compositional shifts in bowel bacterial communities of humans
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, 9054, New Zealand
    Trends Microbiol 16:488-95. 2008
  5. pmc Impact of consumption of oligosaccharide-containing biscuits on the fecal microbiota of humans
    Gerald W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 70:2129-36. 2004
  6. pmc A special fondness for lactobacilli
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 70:3189-94. 2004
  7. pmc Epidemiology, relative invasive ability, molecular characterization, and competitive performance of Campylobacter jejuni strains in the chicken gut
    Christopher Pope
    Department of Microbiology and Immunology, University of Otago, P O Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 73:7959-66. 2007
  8. ncbi request reprint Commentary: Remembrance of microbes past
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Int J Epidemiol 34:13-5. 2005
  9. ncbi request reprint What immunologists should know about bacterial communities of the human bowel
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, P O Box 56, 720 Cumberland Street, Dunedin, New Zealand
    Semin Immunol 19:94-105. 2007
  10. doi request reprint Molecular analysis of the intestinal microflora in IBD
    G W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Mucosal Immunol 1:S15-8. 2008

Collaborators

Detail Information

Publications49

  1. pmc Resource partitioning in relation to cohabitation of Lactobacillus species in the mouse forestomach
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    ISME J 6:927-38. 2012
    ..This real life, trophic phenomenon conforms to a mathematical model based on in vitro bacterial doubling times, in vitro transport rates, and concentrations of maltose and glucose in mouse stomach digesta...
  2. ncbi request reprint Probiotic properties of lactic-acid bacteria: plenty of scope for fundamental R & D
    G W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Trends Biotechnol 15:270-4. 1997
    ..The development of scientifically valid probiotics requires more detailed knowledge of this intestinal microflora than is currently available...
  3. ncbi request reprint Probiotics: time for a dose of realism
    Gerald W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Curr Issues Intest Microbiol 4:33-42. 2003
    ..These new products, however, will need to be targeted at the alleviation of specific medical conditions, and the mechanistic basis of their effectiveness will need to be provided...
  4. doi request reprint The search for disease-associated compositional shifts in bowel bacterial communities of humans
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, 9054, New Zealand
    Trends Microbiol 16:488-95. 2008
    ..Therefore, important challenges remain for bacteriologists in investigations of the bowel bacterial community in relation to disease...
  5. pmc Impact of consumption of oligosaccharide-containing biscuits on the fecal microbiota of humans
    Gerald W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 70:2129-36. 2004
    ..Our observations suggest that a phylogenetic approach to analysis of the gut ecosystem may not always be optimal and that a more physiological (biochemical) method might be more informative...
  6. pmc A special fondness for lactobacilli
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 70:3189-94. 2004
  7. pmc Epidemiology, relative invasive ability, molecular characterization, and competitive performance of Campylobacter jejuni strains in the chicken gut
    Christopher Pope
    Department of Microbiology and Immunology, University of Otago, P O Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 73:7959-66. 2007
    ..jejuni, that some Campylobacter strains detected in poultry meat are of higher virulence for humans than others, and that bacterial attributes affecting strain virulence and commensal colonization ability may be linked...
  8. ncbi request reprint Commentary: Remembrance of microbes past
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Int J Epidemiol 34:13-5. 2005
  9. ncbi request reprint What immunologists should know about bacterial communities of the human bowel
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, P O Box 56, 720 Cumberland Street, Dunedin, New Zealand
    Semin Immunol 19:94-105. 2007
    ..The role of the bacterial community in the development and regulation of the immune system of neonates seems likely to be a particularly important area of future research...
  10. doi request reprint Molecular analysis of the intestinal microflora in IBD
    G W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Mucosal Immunol 1:S15-8. 2008
    ..Although alterations in the composition of the microbiota can be demonstrated, future studies need to provide functional links between the candidate proinflammatory agents and disease processes...
  11. pmc Ecological behavior of Lactobacillus reuteri 100-23 is affected by mutation of the luxS gene
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 71:8419-25. 2005
    ..These results demonstrate that LuxS influences important ecological attributes of L. reuteri 100-23C, the consequences of which are niche specific...
  12. pmc Identification of Lactobacillus isolates from the gastrointestinal tract, silage, and yoghurt by 16S-23S rRNA gene intergenic spacer region sequence comparisons
    G W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 65:4264-7. 1999
    ..It had an advantage over 16S V2-V3 sequence comparisons because it distinguished between isolates of Lactobacillus casei and Lactobacillus rhamnosus...
  13. ncbi request reprint The bowel microflora: an important source of urinary tract pathogens
    G W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    World J Urol 17:339-44. 1999
    ..This, in turn, would decrease the dose of potential urinary tract pathogens present in the faeces...
  14. pmc Analysis of the fecal microflora of human subjects consuming a probiotic product containing Lactobacillus rhamnosus DR20
    G W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 66:2578-88. 2000
    ....
  15. ncbi request reprint Molecular assessment of intestinal microflora
    G W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Am J Clin Nutr 73:410S-414S. 2001
    ..This experimental approach would provide information on the effect of the probiotic on indigenous strains inhabiting the intestinal tract of humans and other animals...
  16. ncbi request reprint New perceptions of the gut microbiota: implications for future research
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, 720 Cumberland Street, PO Box 56, Dunedin, New Zealand
    Gastroenterol Clin North Am 34:361-82, vii. 2005
  17. ncbi request reprint The bifidobacterial and Lactobacillus microflora of humans
    Gerald W Tannock
    Department of Microbiology, University of Otago, PO Box 56, Dunedin, New Zealand
    Clin Rev Allergy Immunol 22:231-53. 2002
  18. ncbi request reprint Molecular methods for exploring the intestinal ecosystem
    G W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Br J Nutr 87:S199-201. 2002
    ..Altered bacterial populations associated with disease states can then be targeted for further investigation. In the long-term, an 'abnormal microflora' might be rectified by the use of probiotics or prebiotics...
  19. ncbi request reprint Exploring the relationships between intestinal microflora and inflammatory conditions of the human bowel and spine
    Gerald W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Antonie Van Leeuwenhoek 81:529-35. 2002
  20. ncbi request reprint PCR/DGGE and 16S rRNA gene library analysis of the colonic microbiota of HLA-B27/beta2-microglobulin transgenic rats
    W McBurney
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Lett Appl Microbiol 42:165-71. 2006
    ....
  21. ncbi request reprint Analysis of the intestinal microflora using molecular methods
    G W Tannock
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Eur J Clin Nutr 56:S44-9. 2002
    ..PCR/DGGE provides a useful screening method to determine the impact of antibiotic treatment on the composition of the intestinal microflora of children and to identify the bacterial groups that are most affected...
  22. ncbi request reprint Analysis of the large bowel microbiota of colitic mice using PCR/DGGE
    R Bibiloni
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Lett Appl Microbiol 41:45-51. 2005
    ....
  23. doi request reprint A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficile-infected patients than does vancomycin
    Gerald W Tannock
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Microbiology 156:3354-9. 2010
    ..These findings help to explain the substantially reduced rates of relapse following treatment of CDI with fidaxomicin in recent clinical trials...
  24. ncbi request reprint The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients
    Rodrigo Bibiloni
    Department of Agricultural, Food and Nutritional Science, University of Otago, PO Box 56, Dunedin, New Zealand
    J Med Microbiol 55:1141-9. 2006
    ..The observations made in this study should permit targeting of specific bacteriological abnormalities in investigations of the pathogenesis of inflammatory bowel diseases and provide targets for medical interventions...
  25. doi request reprint The immune response to autologous bacteroides in ankylosing spondylitis is characterized by reduced interleukin 10 production
    Simon M Stebbings
    Department of Medicine, University of Otago School of Medicine, PO Box 913, Dunedin 9054, New Zealand
    J Rheumatol 36:797-800. 2009
    ..In order to investigate the host immune response in AS, we measured cytokines in tissue culture following exposure of peripheral blood mononuclear cells (PBMC) to autologous colonic bacteria...
  26. doi request reprint A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trial
    Kristin Wickens
    Wellington Asthma Research Group, Wellington School of Medicine and Health Sciences, University of Otago, Wellington, New Zealand
    J Allergy Clin Immunol 122:788-94. 2008
    ..The role of probiotics in prevention of allergic disease is still not clearly established, although early reports suggested Lactobacillus GG halved the risk of eczema at 2 years...
  27. pmc A high-molecular-mass surface protein (Lsp) and methionine sulfoxide reductase B (MsrB) contribute to the ecological performance of Lactobacillus reuteri in the murine gut
    Jens Walter
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 71:979-86. 2005
    ..Homologues of lsp and msrB are present in the genomes of several strains of Lactobacillus and may play an important role in the maintenance of these bacteria in gut ecosystems...
  28. pmc Identification, detection, and enumeration of human bifidobacterium species by PCR targeting the transaldolase gene
    Teresa Requena
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 68:2420-7. 2002
    ..In the case of samples from infants, 16S rDNA-targeted PCR was superior to PCR targeting the transaldolase gene for the quantification of bifidobacterial populations...
  29. ncbi request reprint D-alanyl ester depletion of teichoic acids in Lactobacillus reuteri 100-23 results in impaired colonization of the mouse gastrointestinal tract
    Jens Walter
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Environ Microbiol 9:1750-60. 2007
    ..This study showed that D-alanylation is an important cell function of L. reuteri that seems to protect this commensal organism against the hostile conditions prevailing in the murine forestomach...
  30. pmc Influence of different functional elements of plasmid pGT232 on maintenance of recombinant plasmids in Lactobacillus reuteri populations in vitro and in vivo
    N C Heng
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Appl Environ Microbiol 65:5378-85. 1999
    ..0-kb sequence which contained a putative single-strand replication origin (SSO). The SSO of pGT232 is believed to be novel and functions in an orientation-specific manner...
  31. pmc Bifidobacterial species differentially affect expression of cell surface markers and cytokines of dendritic cells harvested from cord blood
    Sarah L Young
    Department of Microbiology, University of Otago, Dunedin, New Zealand
    Clin Diagn Lab Immunol 11:686-90. 2004
    ..bifidum, B. longum, and B. pseudocatenulatum induce a Th2-driven immune response. A hypothesis is presented to link our observations to the prevalence of atopic diseases in different countries...
  32. doi request reprint Glucosyltransferase A (GtfA) and inulosucrase (Inu) of Lactobacillus reuteri TMW1.106 contribute to cell aggregation, in vitro biofilm formation, and colonization of the mouse gastrointestinal tract
    Jens Walter
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Microbiology 154:72-80. 2008
    ..From the evidence provided in this study we conclude that GtfA and Inu confer important ecological attributes of L. reuteri TMW1.106 and contribute to colonization of the mouse gastrointestinal tract...
  33. doi request reprint Gut commensal Lactobacillus reuteri 100-23 stimulates an immunoregulatory response
    Megan Livingston
    Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand
    Immunol Cell Biol 88:99-102. 2010
    ..reuteri 100-23 stimulated the development of an increased number of regulatory T cells...
  34. pmc Construction, analysis, and beta-glucanase screening of a bacterial artificial chromosome library from the large-bowel microbiota of mice
    Jens Walter
    Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin, New Zealand
    Appl Environ Microbiol 71:2347-54. 2005
    ....
  35. pmc Detection and identification of Lactobacillus species in crops of broilers of different ages by using PCR-denaturing gradient gel electrophoresis and amplified ribosomal DNA restriction analysis
    Le Luo Guan
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5
    Appl Environ Microbiol 69:6750-7. 2003
    ..The results of our study provide comprehensive knowledge of the Lactobacillus microflora in the crops of birds of different ages using nucleic acid-based methods of detection and identification based on current taxonomic criteria...
  36. pmc Identification of Lactobacillus reuteri genes specifically induced in the mouse gastrointestinal tract
    Jens Walter
    Institute of Food Technology, University of Hohenheim, Stuttgart, Germany
    Appl Environ Microbiol 69:2044-51. 2003
    ..Our IVET system has the potential to identify genes of lactobacilli that have not previously been functionally characterized but which may be essential for growth of these bacteria in the gastrointestinal ecosystem...
  37. pmc Effects of dietary fat source and subtherapeutic levels of antibiotic on the bacterial community in the ileum of broiler chickens at various ages
    Ane Knarreborg
    Department of Animal Nutrition and Physiology, Danish Institute of Agricultural Sciences, Research Centre Foulum, Tjele, Denmark
    Appl Environ Microbiol 68:5918-24. 2002
    ..Moreover, different strains (clonal variants of the alpha-toxin gene) of C. perfringens type A were detected in response to age, dietary fat source, and dietary supplementation with antibiotics...
  38. ncbi request reprint Differential clustering of bowel biopsy-associated bacterial profiles of specimens collected in Mexico and Canada: what do these profiles represent?
    Rodrigo Bibiloni
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada
    J Med Microbiol 57:111-7. 2008
    ..Therefore, biopsy-associated bacteria are likely to represent, at least in part, contaminants from the fluid, which resembles a faecal solution, that pools in the bowel after cleansing prior to endoscopy...
  39. ncbi request reprint Effect of a milk formula containing probiotics on the fecal microbiota of asian infants at risk of atopic diseases
    Ka Weng Mah
    Department of Paediatrics, National University of Singapore, Singapore 119074
    Pediatr Res 62:674-9. 2007
    ..4 versus 7.4; p = 0.035). Our results indicate that supplemented strains could be detected but did not persist in the bowel once probiotic administration had ceased...
  40. ncbi request reprint Reduction of colitis by prebiotics in HLA-B27 transgenic rats is associated with microflora changes and immunomodulation
    Frank Hoentjen
    Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, North Carolina, USA
    Inflamm Bowel Dis 11:977-85. 2005
    ..These results show promise for prebiotics as primary or adjuvant maintenance therapy for chronic inflammatory bowel diseases...
  41. pmc Detection, characterization, and in vitro and in vivo expression of genes encoding S-proteins in Lactobacillus gallinarum strains isolated from chicken crops
    Karen E Hagen
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Canada
    Appl Environ Microbiol 71:6633-43. 2005
    ..The results of this study provide a basis for the investigation of gene duplication and sequence variation as mechanisms by which bacterial strains of the same species can share the same habitat...
  42. pmc Supplementation of the diet with high-viscosity beta-glucan results in enrichment for lactobacilli in the rat cecum
    Jennifer Snart
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada
    Appl Environ Microbiol 72:1925-31. 2006
    ..The results of this study have relevance to the use of purified beta-glucan products as dietary supplements for human consumption...
  43. ncbi request reprint Dietary fibres as "prebiotics": implications for colorectal cancer
    Chiara C Lim
    Discipline of Nutrition, Faculty of Medicine and Health Sciences, The University of Auckland, Auckland, New Zealand
    Mol Nutr Food Res 49:609-19. 2005
    ..However, their mechanisms of action in humans are speculative, and research aimed at providing an integrated view of the gut microbiota and dietary fibre nutrition of humans needs to be developed...
  44. pmc Real-time quantitative PCR measurement of ileal Lactobacillus salivarius populations from broiler chickens to determine the influence of farming practices
    Sally A Harrow
    New Zealand Institute for Crop and Food Research Limited, Christchurch, New Zealand
    Appl Environ Microbiol 73:7123-7. 2007
    ..salivarius population relative to that of chickens given the control diet, as did administration of bacitracin and monensin in the feed. These changes in the target bacterial population were associated with improved broiler weight gain...
  45. ncbi request reprint Bifidobacterium pseudocatenulatum is associated with atopic eczema: a nested case-control study investigating the fecal microbiota of infants
    Claudia Gore
    North West Lung Research Center, Wythenshawe Hospital, Manchester, United Kingdom
    J Allergy Clin Immunol 121:135-40. 2008
    ..Exposure to specific bacterial bowel commensals may increase/reduce the risk of atopic diseases...
  46. ncbi request reprint Sucrose utilization and impact of sucrose on glycosyltransferase expression in Lactobacillus reuteri
    Clarissa Schwab
    Department Agricultural Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada
    Syst Appl Microbiol 30:433-43. 2007
    ..Our data thus indicate that these glycosyltransferases affect the competitiveness of some L. reuteri strains in ecosystems where sucrose is present...
  47. ncbi request reprint Hygeia versus Asclepius
    Gerald W Tannock
    Future Microbiol 1:345-9. 2006
  48. doi request reprint Analysis of bacterial bowel communities of IBD patients: what has it revealed?
    Harry Sokol
    Gastroenterology and Nutrition Unit, Saint Antoine Hospital, APHP, Paris, France
    Inflamm Bowel Dis 14:858-67. 2008
    ..Confounding factors need to be eliminated from future studies by using better-defined patient populations of newly diagnosed and untreated individuals and by improved sampling procedures...
  49. ncbi request reprint VSL#3 probiotic-mixture induces remission in patients with active ulcerative colitis
    Rodrigo Bibiloni
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada
    Am J Gastroenterol 100:1539-46. 2005
    ..We evaluated the safety and efficacy of VSL#3 and the components, and the composition of the biopsy-associated microbiota in patients with active mild to moderate ulcerative colitis (UC)...