W H Sutherland

Summary

Affiliation: University of Otago
Country: New Zealand

Publications

  1. ncbi Ingestion of native and thermally oxidized polyunsaturated fats acutely increases circulating numbers of endothelial microparticles
    Wayne H F Sutherland
    Medicine Section, Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin 9054, New Zealand
    Metabolism 59:446-53. 2010
  2. ncbi Hypochlorous acid and low serum paraoxonase activity in haemodialysis patients: an in vitro study
    Wayne H F Sutherland
    Department of Medical and Surgical Sciences, University of Otago Medical School, PO Box 913, Dunedin, New Zealand
    Nephrol Dial Transplant 19:75-82. 2004
  3. ncbi Effect of meals rich in heated olive and safflower oils on oxidation of postprandial serum in healthy men
    Wayne H F Sutherland
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago Medical School, PO Box 913, Dunedin, New Zealand
    Atherosclerosis 160:195-203. 2002
  4. ncbi Hypochlorous acid and 3,4-dihydroxyphenylalanine increase the formation of serum protein lipofuscin-like fluorophores in vitro
    Wayne H F Sutherland
    Department of Medical and Surgical Sciences, University of Otago, Dunedin, New Zealand
    Ren Fail 27:239-46. 2005
  5. ncbi Vitamin E supplementation and plasma 8-isoprostane and adiponectin in overweight subjects
    Wayne H F Sutherland
    Medicine Section, Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Obesity (Silver Spring) 15:386-91. 2007
  6. ncbi Effect of dietary cholesterol and fat on cell cholesterol transfer to postprandial plasma in hyperlipidemic men
    Wayne H F Sutherland
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin 9054, New Zealand
    Lipids 42:901-11. 2007
  7. ncbi Plasma protein lipofuscin-like fluorophores in men with coronary artery disease treated with statins
    Wayne H Sutherland
    Department of Medical and Surgical Sciences, University of Otago, Dunedin, New Zealand
    Arch Med Res 38:757-63. 2007
  8. ncbi Reduced postprandial serum paraoxonase activity after a meal rich in used cooking fat
    W H Sutherland
    Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Arterioscler Thromb Vasc Biol 19:1340-7. 1999
  9. ncbi Serum protein-bound 3,4-dihydroxyphenylalanine and related products of protein oxidation and chronic hemodialysis
    Wayne H F Sutherland
    Department of Medical and Surgical Sciences, University of Otago, Dunedin, New Zealand
    Ren Fail 25:997-1009. 2003
  10. ncbi Vitamin C improves endothelial dysfunction in renal allograft recipients
    M J Williams
    Department of Medicine, University of Otago, PO Box 913, Dunedin, New Zealand
    Nephrol Dial Transplant 16:1251-5. 2001

Collaborators

Detail Information

Publications26

  1. ncbi Ingestion of native and thermally oxidized polyunsaturated fats acutely increases circulating numbers of endothelial microparticles
    Wayne H F Sutherland
    Medicine Section, Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin 9054, New Zealand
    Metabolism 59:446-53. 2010
    ..The physiologic implications of these findings remain to be determined...
  2. ncbi Hypochlorous acid and low serum paraoxonase activity in haemodialysis patients: an in vitro study
    Wayne H F Sutherland
    Department of Medical and Surgical Sciences, University of Otago Medical School, PO Box 913, Dunedin, New Zealand
    Nephrol Dial Transplant 19:75-82. 2004
    ..We have examined the effect of HOCl and the uraemic milieu on serum PON1 arylesterase activity and the ability of HDL to inhibit LDL oxidation in vitro...
  3. ncbi Effect of meals rich in heated olive and safflower oils on oxidation of postprandial serum in healthy men
    Wayne H F Sutherland
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago Medical School, PO Box 913, Dunedin, New Zealand
    Atherosclerosis 160:195-203. 2002
    ..These findings may be relevant to the choice of fat to replace saturated fats in lipid-lowering diets and to low risk of coronary heart disease in communities which have a high consumption of olive oil...
  4. ncbi Hypochlorous acid and 3,4-dihydroxyphenylalanine increase the formation of serum protein lipofuscin-like fluorophores in vitro
    Wayne H F Sutherland
    Department of Medical and Surgical Sciences, University of Otago, Dunedin, New Zealand
    Ren Fail 27:239-46. 2005
    ..To investigate the possibility that hypochlorous acid (HOCl) and 3,4-dihydroxyphenylalanine (DOPA) may contribute to high LLFs concentrations, we have examined the effect of these factors on serum protein LLF formation in vitro...
  5. ncbi Vitamin E supplementation and plasma 8-isoprostane and adiponectin in overweight subjects
    Wayne H F Sutherland
    Medicine Section, Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Obesity (Silver Spring) 15:386-91. 2007
    ..The aim of this study was to determine the effect of vitamin E supplementation on plasma concentrations of 8-isoprostane and adiponectin in overweight/obese subjects...
  6. ncbi Effect of dietary cholesterol and fat on cell cholesterol transfer to postprandial plasma in hyperlipidemic men
    Wayne H F Sutherland
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin 9054, New Zealand
    Lipids 42:901-11. 2007
    ....
  7. ncbi Plasma protein lipofuscin-like fluorophores in men with coronary artery disease treated with statins
    Wayne H Sutherland
    Department of Medical and Surgical Sciences, University of Otago, Dunedin, New Zealand
    Arch Med Res 38:757-63. 2007
    ..The aim of this study was to compare plasma concentrations of P-LLF between men with coronary artery disease (CAD) treated with statin drugs and healthy controls and to identify determinants of P-LLF...
  8. ncbi Reduced postprandial serum paraoxonase activity after a meal rich in used cooking fat
    W H Sutherland
    Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Arterioscler Thromb Vasc Biol 19:1340-7. 1999
    ....
  9. ncbi Serum protein-bound 3,4-dihydroxyphenylalanine and related products of protein oxidation and chronic hemodialysis
    Wayne H F Sutherland
    Department of Medical and Surgical Sciences, University of Otago, Dunedin, New Zealand
    Ren Fail 25:997-1009. 2003
    ..Hemodialysis and uremic toxins can activate leukocytes leading to overproduction of reactive oxygen species such as hydrogen peroxide and hypochlorous acid (HOCl) that increases protein oxidation...
  10. ncbi Vitamin C improves endothelial dysfunction in renal allograft recipients
    M J Williams
    Department of Medicine, University of Otago, PO Box 913, Dunedin, New Zealand
    Nephrol Dial Transplant 16:1251-5. 2001
    ..001). CONCLUSIONS: Vitamin C acutely improves flow-mediated, endothelium-dependent dilation and increases the resistance of lipoproteins in dilute serum to oxidation in renal transplant recipients...
  11. ncbi Impaired endothelial function following a meal rich in used cooking fat
    M J Williams
    Department of Medicine, University of Otago, Dunedin, New Zealand
    J Am Coll Cardiol 33:1050-5. 1999
    ..The purpose of this study was to test the hypothesis that intake of used cooking fat is associated with impaired endothelial function...
  12. ncbi The effect of hormone replacement therapy on cardiovascular risk factors in type 2 diabetes: a randomized controlled trial
    P J Manning
    Department of Medicine, Dunedin Hospital, 201 Great King St, Dunedin, New Zealand
    Arch Intern Med 161:1772-6. 2001
    ..We evaluated the effect of combined continuous HRT on lipoprotein and coagulation factor concentrations and glycemic control in postmenopausal women with type 2 diabetes mellitus...
  13. ncbi The effects of sequential combined oral 17beta-estradiol norethisterone acetate on insulin sensitivity and body composition in healthy postmenopausal women: a randomized single blind placebo-controlled study
    R J Walker
    Department of Medicine, Dunedin School of Medicine, University of Otago, New Zealand
    Menopause 8:27-32. 2001
    ....
  14. ncbi The effect of meals rich in thermally stressed olive and safflower oils on postprandial serum paraoxonase activity in patients with diabetes
    A J Wallace
    Department of Human Nutrition, University of Otago, Dunedin, New Zealand
    Eur J Clin Nutr 55:951-8. 2001
    ..SPONSORSHIP: The study was supported by a grant from the National Heart Foundation of New Zealand...
  15. ncbi Normal endothelial function after meals rich in olive or safflower oil previously used for deep frying
    M J Williams
    Department of Medicine, Dunedin School of Medicine, University of Otago, 201 Great King Street, Dunedin, New Zealand
    Nutr Metab Cardiovasc Dis 11:147-52. 2001
    ..These findings suggest that relatively short-term use of these vegetable oils for frying may not adversely affect postprandial endothelial function when foods containing the heat-modified oils are consumed...
  16. ncbi Hormone-replacement therapy increases serum paraoxonase arylesterase activity in diabetic postmenopausal women
    W H Sutherland
    Division of Medicine, Department of Medical and Surgical Sciences, University of Otago Medical School, Dunedin, New Zealand
    Metabolism 50:319-24. 2001
    ....
  17. ncbi Release of cholesterol from cell membranes to postprandial plasma from mildly hypercholesterolemic subjects: the effect of meals rich in olive and safflower oils
    Wayne H F Sutherland
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago Medical School, Dunedin, New Zealand
    Metabolism 51:1306-12. 2002
    ..Thus, low-fat, lipid-lowering diets may have a minimal effect on this capacity but will reduce levels of atherogenic LDL cholesterol that appear to be maintained by diffusion of cell cholesterol to plasma...
  18. ncbi Postprandial cytokine concentrations and meal composition in obese and lean women
    Patrick J Manning
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Obesity (Silver Spring) 16:2046-52. 2008
    ..These findings suggest that the postprandial response of plasma IL-6 concentrations may be influenced by the type of carbohydrate in the meal, central adiposity, and circulating cortisol concentrations in women...
  19. ncbi Effect of high-dose vitamin E on insulin resistance and associated parameters in overweight subjects
    Patrick J Manning
    Department of Medical and Surgical Sciences, University of Otago, Private Bag, Dunedin, New Zealand
    Diabetes Care 27:2166-71. 2004
    ..Vitamin E improves glycemic control in people with diabetes. We tested the hypothesis that vitamin E would decrease markers of oxidative stress and plasma ALT levels and improve insulin sensitivity in overweight individuals...
  20. ncbi Variation in the cholesteryl ester transfer protein (CETP) gene does not influence individual plasma cholesterol response to changes in the nature of dietary fat
    Wendy A E Aitken
    Department of Human Nutrition, University of Otago, Dunedin, New Zealand
    Nutr Metab Cardiovasc Dis 16:353-63. 2006
    ....
  21. ncbi The effect of rosiglitazone on oxidative stress and insulin resistance in overweight individuals
    Patrick J Manning
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Diabetes Res Clin Pract 81:209-15. 2008
    ..In addition we examined the effect of rosiglitazone on post-glucose challenge levels of glucose and insulin...
  22. ncbi HRT does not improve urinary albumin excretion in postmenopausal diabetic women
    Patrick J Manning
    Department of Medical and Surgical Sciences, Dunedin Hospital, University of Otago Medical School, PO Box 913, New Zealand
    Diabetes Res Clin Pract 60:33-9. 2003
    ..These data suggest that 6 months HRT does not reverse microalbuminuria caused by prolonged hyperglycaemia and other risk factors that underlie leakage of albumin into the urine in postmenopausal women with type 2 diabetes...
  23. ncbi Acute effect of drinking red and white wines on circulating levels of inflammation-sensitive molecules in men with coronary artery disease
    Michael J A Williams
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Ontago, Dunedin, New Zealand
    Metabolism 53:318-23. 2004
    ..These data suggest that moderate wine intake may acutely increase plasma levels of IL-6 in men with CAD. It is possible that this increase in plasma IL-6 is a response to alcohol-induced oxidative stress in the liver...
  24. ncbi The effect of glucose ingestion on inflammation and oxidative stress in obese individuals
    Patrick J Manning
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Metabolism 57:1345-9. 2008
    ....
  25. ncbi Aged garlic extract improves endothelial function in men with coronary artery disease
    Michael J A Williams
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Phytother Res 19:314-9. 2005
    ..Whether improvement in endothelial function decreases the risk of future cardiovascular events remains to be determined...
  26. ncbi The impact of standard high-flux polysulfone versus novel high-flux polysulfone dialysis membranes on inflammatory markers: a randomized, single-blinded, controlled clinical trial
    Peter G Kerr
    Department of Nephrology, Monash Medical Centre, Victoria, Australia
    Am J Kidney Dis 49:533-9. 2007
    ....