Leo J Schep

Summary

Affiliation: University of Otago
Country: New Zealand

Publications

  1. doi request reprint Delayed seizure-like activity following analytically confirmed use of previously unreported synthetic cannabinoid analogues
    L J Schep
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Hum Exp Toxicol 34:557-60. 2015
  2. doi request reprint The clinical toxicology of γ-hydroxybutyrate, γ-butyrolactone and 1,4-butanediol
    Leo J Schep
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 50:458-70. 2012
  3. doi request reprint The clinical toxicology of the designer "party pills" benzylpiperazine and trifluoromethylphenylpiperazine
    Leo J Schep
    Department of Preventive and Social Medicine, National Poisons Centre, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 49:131-41. 2011
  4. doi request reprint The clinical toxicology of metamfetamine
    Leo J Schep
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 48:675-94. 2010
  5. doi request reprint Nicotinic plant poisoning
    Leo J Schep
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 47:771-81. 2009
  6. doi request reprint Diethylene glycol poisoning
    Leo J Schep
    Department of Preventive and Social Medicine, National Poisons Centre, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 47:525-35. 2009
  7. doi request reprint Poisoning due to water hemlock
    Leo J Schep
    Department of Preventive and Social Medicine, National Poisons Centre, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 47:270-8. 2009
  8. doi request reprint Was the death of Alexander the Great due to poisoning? Was it Veratrum album?
    Leo J Schep
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 52:72-7. 2014
  9. ncbi request reprint Poisonous plants in New Zealand: a review of those that are most commonly enquired about to the National Poisons Centre
    Robin J Slaughter
    National Poisons Centre, University of Otago, PO Box 913, Dunedin, New Zealand
    N Z Med J 125:87-118. 2012
  10. pmc Full recovery from a potentially lethal dose of mercuric chloride
    D Michael G Beasley
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, P O Box 913, Dunedin, New Zealand
    J Med Toxicol 10:40-4. 2014

Collaborators

Detail Information

Publications15

  1. doi request reprint Delayed seizure-like activity following analytically confirmed use of previously unreported synthetic cannabinoid analogues
    L J Schep
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Hum Exp Toxicol 34:557-60. 2015
    ..Clinicians should be aware that synthetic cannabinoids may cause an array of severe health consequences. Given the ever evolving structure of available analogues, clinicians must also be prepared for other unexpected adverse effects. ..
  2. doi request reprint The clinical toxicology of γ-hydroxybutyrate, γ-butyrolactone and 1,4-butanediol
    Leo J Schep
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 50:458-70. 2012
    ..We review the epidemiology, mechanisms of toxicity, toxicokinetics, clinical features, diagnosis, and management of poisoning due to GHB and its analogs and discuss the features and management of GHB withdrawal...
  3. doi request reprint The clinical toxicology of the designer "party pills" benzylpiperazine and trifluoromethylphenylpiperazine
    Leo J Schep
    Department of Preventive and Social Medicine, National Poisons Centre, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 49:131-41. 2011
    ..This article will review the mechanisms of toxicity, toxicokinetics, clinical features, diagnosis, and management of poisoning due to BZP and TFMPP...
  4. doi request reprint The clinical toxicology of metamfetamine
    Leo J Schep
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 48:675-94. 2010
    ..An understanding of the drug's toxic effects and their medical treatment is therefore essential for the successful management of patients suffering this form of intoxication...
  5. doi request reprint Nicotinic plant poisoning
    Leo J Schep
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 47:771-81. 2009
    ..The toxicokinetics and mechanisms of toxicity of these alkaloids are reviewed and the clinical features and management of poisoning due to these plants are described...
  6. doi request reprint Diethylene glycol poisoning
    Leo J Schep
    Department of Preventive and Social Medicine, National Poisons Centre, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 47:525-35. 2009
    ..Despite DEG's toxicity and associated epidemics of fatal poisonings, a comprehensive review has not been published...
  7. doi request reprint Poisoning due to water hemlock
    Leo J Schep
    Department of Preventive and Social Medicine, National Poisons Centre, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 47:270-8. 2009
    ..Despite their toxicity, the literature consists almost entirely of case reports...
  8. doi request reprint Was the death of Alexander the Great due to poisoning? Was it Veratrum album?
    Leo J Schep
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Clin Toxicol (Phila) 52:72-7. 2014
    ..To investigate the death of Alexander the Great to determine if he died from natural causes or was poisoned and, if the latter, what was the most likely poison...
  9. ncbi request reprint Poisonous plants in New Zealand: a review of those that are most commonly enquired about to the National Poisons Centre
    Robin J Slaughter
    National Poisons Centre, University of Otago, PO Box 913, Dunedin, New Zealand
    N Z Med J 125:87-118. 2012
    ..Poisonous plants can cause harm following inadvertent ingestion, via skin contact, eye exposures or inhalation of sawdust or smoked plant matter...
  10. pmc Full recovery from a potentially lethal dose of mercuric chloride
    D Michael G Beasley
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, P O Box 913, Dunedin, New Zealand
    J Med Toxicol 10:40-4. 2014
    ..Mercuric chloride poisoning is rare yet potentially life-threatening. We report a case of poisoning with a potentially significant amount of mercuric chloride which responded to aggressive management...
  11. doi request reprint Ricin as a weapon of mass terror--separating fact from fiction
    Leo J Schep
    National Poisons Centre, University of Otago, Dunedin, New Zealand
    Environ Int 35:1267-71. 2009
    ..Ricin as a toxin is deadly but as an agent of bioterror it is unsuitable and therefore does not deserve the press attention and subsequent public alarm that has been created...
  12. ncbi request reprint New Zealand's venomous creatures
    Robin J Slaughter
    New Zealand National Poisons Centre, University of Otago, Dunedin, New Zealand
    N Z Med J 122:83-97. 2009
    ..New Zealand is home to a small number of venomous creatures. The purpose of this review is to educate and update healthcare professionals on the management of envenoming from these creatures...
  13. doi request reprint Riot control agents: the tear gases CN, CS and OC-a medical review
    Leo J Schep
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    J R Army Med Corps 161:94-9. 2015
    ..The aim of this narrative review is to summarise all main aspects of the riot control agents CN, CS and OC toxicology, including mechanisms of toxicity, clinical features and management...
  14. ncbi request reprint Poisoning following exposure to chemicals stored in mislabelled or unlabelled containers: a recipe for potential disaster
    Yvette C Millard
    National Poisons Centre, Department of Preventive and Social Medicine, University of Otago, PO Box 56, Dunedin, New Zealand
    N Z Med J 127:17-23. 2014
    ..To investigate poisoning exposures to chemicals that were unlabelled, mislabelled or not in their original containers in New Zealand over the last 10 years, based on calls to the New Zealand National Poisons Centre (NZNPC)...
  15. ncbi request reprint Veratrum poisoning
    Leo J Schep
    National Poisons Centre, University of Otago, Dunedin, New Zealand
    Toxicol Rev 25:73-8. 2006
    ..The onset of symptoms occurs between 30 minutes and 4 hours, and the duration of the illness can range from 1 to 10 days; however, with prompt supportive care, patients typically make a full recovery within 24 hours...