Timothy A Sato

Summary

Affiliation: University of Auckland
Country: New Zealand

Publications

  1. ncbi request reprint Gestational age-dependent effects of lipopolysaccharide on prostaglandin production by murine decidual caps
    T A Sato
    Liggins Institute and Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    Prostaglandins Leukot Essent Fatty Acids 64:135-8. 2001
  2. ncbi request reprint Cytosolic phospholipase A(2)and 15-hydroxyprostaglandin dehydrogenase mRNA expression in murine uterine and gestational tissues during late pregnancy
    T A Sato
    Division of Pharmacology and Clinical Pharmacology and Liggins Institute, University of Auckland, Auckland, New Zealand
    Prostaglandins Leukot Essent Fatty Acids 64:247-51. 2001
  3. ncbi request reprint Regulation of prostaglandin production in an immortalized human myometrial cell line by cytokines and non-steroidal anti-inflammatory drugs
    Timothy A Sato
    The Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, Liggins Institute, University of Auckland, Private Bag 92019, Auckland, New Zealand
    Eur J Obstet Gynecol Reprod Biol 100:158-62. 2002
  4. ncbi request reprint Expression of interleukin-1beta mRNA in murine uterine and gestational tissues: relationship with gestational age
    T A Sato
    Liggins Institute and Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, New Zealand
    Am J Reprod Immunol 46:413-9. 2001
  5. ncbi request reprint Efficacy and specificity of non-steroidal anti-inflammatory drugs for the inhibition of cytokine-stimulated prostaglandin E(2) secretion by amnion-derived WISH cells
    T A Sato
    Faculty of Medical and Health Sciences, Division of Pharmacology and Clinical Pharmacology, Liggins Institute, University of Auckland, Auckland, New Zealand
    Prostaglandins Leukot Essent Fatty Acids 66:525-7. 2002
  6. ncbi request reprint Critical paracrine interactions between TNF-alpha and IL-10 regulate lipopolysaccharide-stimulated human choriodecidual cytokine and prostaglandin E2 production
    Timothy A Sato
    Liggins Institute and Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    J Immunol 170:158-66. 2003
  7. ncbi request reprint Cannabinoids stimulate prostaglandin production by human gestational tissues through a tissue- and CB1-receptor-specific mechanism
    Murray D Mitchell
    Liggins Institute, University of Auckland, Auckland, New Zealand
    Am J Physiol Endocrinol Metab 294:E352-6. 2008
  8. ncbi request reprint Gestational age-dependent up-regulation of prostaglandin D synthase (PGDS) and production of PGDS-derived antiinflammatory prostaglandins in human placenta
    Rachel J A Helliwell
    The Liggins Institute, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
    J Clin Endocrinol Metab 91:597-606. 2006
  9. ncbi request reprint Identification of 9alpha,11beta-prostaglandin F2 in human amniotic fluid and characterization of its production by human gestational tissues
    Murray D Mitchell
    Liggins Institute, University of Auckland, 2 6 Park Avenue, Grafton, Auckland, New Zealand
    J Clin Endocrinol Metab 90:4244-8. 2005
  10. ncbi request reprint Contact paracrine inhibitory networks within human gestational tissues
    Timothy A Sato
    Liggins Institute, University of Auckland, New Zealand
    Am J Obstet Gynecol 195:1396-7. 2006

Detail Information

Publications17

  1. ncbi request reprint Gestational age-dependent effects of lipopolysaccharide on prostaglandin production by murine decidual caps
    T A Sato
    Liggins Institute and Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    Prostaglandins Leukot Essent Fatty Acids 64:135-8. 2001
    ..However, mice treated at days 15 and 17 had an equal occurrence of premature delivery or fetal resorption. This change in LPS responsiveness may indicate changes in the fetal-maternal immune system in late pregnancy...
  2. ncbi request reprint Cytosolic phospholipase A(2)and 15-hydroxyprostaglandin dehydrogenase mRNA expression in murine uterine and gestational tissues during late pregnancy
    T A Sato
    Division of Pharmacology and Clinical Pharmacology and Liggins Institute, University of Auckland, Auckland, New Zealand
    Prostaglandins Leukot Essent Fatty Acids 64:247-51. 2001
    ..The tissue specific differences in expression of cPLA(2)and PGDH suggest that changes in enzymatic regulation of PG production and degradation may be crucial for the initiation of labour...
  3. ncbi request reprint Regulation of prostaglandin production in an immortalized human myometrial cell line by cytokines and non-steroidal anti-inflammatory drugs
    Timothy A Sato
    The Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, Liggins Institute, University of Auckland, Private Bag 92019, Auckland, New Zealand
    Eur J Obstet Gynecol Reprod Biol 100:158-62. 2002
    ..To test the effect of selective and non-selective inhibitors of prostaglandin H synthase-2 (PGHS-II) on basal and cytokine-stimulated prostaglandin (PG) production by the immortalized human myometrial cell line, UTLRp16...
  4. ncbi request reprint Expression of interleukin-1beta mRNA in murine uterine and gestational tissues: relationship with gestational age
    T A Sato
    Liggins Institute and Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, New Zealand
    Am J Reprod Immunol 46:413-9. 2001
    ..In this study. IL-1beta mRNA in the uterus and gestational tissues of mice during mid to late pregnancy was studied to characterize its tissue specific as well as gestational age expression...
  5. ncbi request reprint Efficacy and specificity of non-steroidal anti-inflammatory drugs for the inhibition of cytokine-stimulated prostaglandin E(2) secretion by amnion-derived WISH cells
    T A Sato
    Faculty of Medical and Health Sciences, Division of Pharmacology and Clinical Pharmacology, Liggins Institute, University of Auckland, Auckland, New Zealand
    Prostaglandins Leukot Essent Fatty Acids 66:525-7. 2002
    ..The results of this study suggest that PGHS-II-selective NSAIDs may be effective in the prevention of cytokine-driven amnion PG production associated with preterm labour...
  6. ncbi request reprint Critical paracrine interactions between TNF-alpha and IL-10 regulate lipopolysaccharide-stimulated human choriodecidual cytokine and prostaglandin E2 production
    Timothy A Sato
    Liggins Institute and Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    J Immunol 170:158-66. 2003
    ..In the setting of an infection of the intrauterine, TNF-alpha may be a potential target for treatment intervention; IL-10 could be one such therapeutic...
  7. ncbi request reprint Cannabinoids stimulate prostaglandin production by human gestational tissues through a tissue- and CB1-receptor-specific mechanism
    Murray D Mitchell
    Liggins Institute, University of Auckland, Auckland, New Zealand
    Am J Physiol Endocrinol Metab 294:E352-6. 2008
    ....
  8. ncbi request reprint Gestational age-dependent up-regulation of prostaglandin D synthase (PGDS) and production of PGDS-derived antiinflammatory prostaglandins in human placenta
    Rachel J A Helliwell
    The Liggins Institute, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
    J Clin Endocrinol Metab 91:597-606. 2006
    ..However, the complexity of these pathways and the mechanism(s) of their coordinated regulation in physiological and pathological conditions are only now being appreciated...
  9. ncbi request reprint Identification of 9alpha,11beta-prostaglandin F2 in human amniotic fluid and characterization of its production by human gestational tissues
    Murray D Mitchell
    Liggins Institute, University of Auckland, 2 6 Park Avenue, Grafton, Auckland, New Zealand
    J Clin Endocrinol Metab 90:4244-8. 2005
    ..9alpha,11beta-Prostaglandin F(2) (9alpha,11beta-PGF(2)) can contract uterine smooth muscle with a potency equal to PGF(2alpha). Its presence in the human uterus and production by human gestational tissues is unknown...
  10. ncbi request reprint Contact paracrine inhibitory networks within human gestational tissues
    Timothy A Sato
    Liggins Institute, University of Auckland, New Zealand
    Am J Obstet Gynecol 195:1396-7. 2006
    ..Chorionic production always exceeded that of decidua. Production rates were significantly greater in separated explants compared with intact choriodecidua, which suggests a potential contact paracrine inhibitory network...
  11. ncbi request reprint Preferential production of prostaglandin D2 by lipopolysaccharide stimulated human choriodecidual explants
    Timothy A Sato
    Liggins Institute, University of Auckland, 2 6 Park Avenue, Grafton, Auckland, New Zealand
    Prostaglandins Leukot Essent Fatty Acids 74:87-92. 2006
    ..Neutralization of TNF-alpha and IL-10 further increased the production of LPS stimulated PGD2 production. We suggest that a novel stimulatory pathway that drives the production of PGD2 has been uncovered...
  12. ncbi request reprint Molecular inhibition of histone deacetylation results in major enhancement of the production of IL-1beta in response to LPS
    Timothy A Sato
    Liggins Institute, Faculty of Medical and Health Sciences, Univ of Auckland, Private Bag 92019, Auckland, New Zealand
    Am J Physiol Endocrinol Metab 290:E490-3. 2006
    ....
  13. ncbi request reprint Misidentification of prostamides as prostaglandins
    Michelle Glass
    Department of Pharmacology, University of Auckland, Auckland, New Zealand
    J Lipid Res 46:1364-8. 2005
    ....
  14. ncbi request reprint Macrophage inhibitory cytokine 1 in fetal membranes and amniotic fluid from pregnancies with and without preterm labour and premature rupture of membranes
    Jeffrey A Keelan
    Liggins Institute, Department of Pharmacology, University of Aukland Faculty of Medical and Health Sciences, Aukland, New Zealand
    Mol Hum Reprod 9:535-40. 2003
    ..We conclude that AF MIC-1 is derived from the fetal membranes and decidua, but that MIC-1 is unlikely to be involved in the pathophysiology of preterm birth or PROM...
  15. ncbi request reprint Expression of angiogenic and neurotrophic factors in the human amnion and choriodecidua
    Keith W Marvin
    Liggins Institute and the Division of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, New Zealand
    Am J Obstet Gynecol 187:728-34. 2002
    ..Our objective was to identify the novel or differential expression of growth or development associated genes in the human gestational membranes that might play roles in pregnancy or in term or preterm parturition...
  16. ncbi request reprint Differential effects of serum constituents on apoptosis induced by the cyclopentenone prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in WISH epithelial cells
    Elicia B E Berry
    Liggins Institute, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
    Prostaglandins Leukot Essent Fatty Acids 71:191-7. 2004
    ..The potential for serum albumin to regulate the bioactivity of cyclopentenone PGs may be of considerable importance in pathological conditions where roles for cyclopentenone PGs have been identified...
  17. ncbi request reprint Hypothermia suppresses inducible nitric oxide synthase and stimulates cyclooxygenase-2 in lipopolysaccharide stimulated BV-2 cells
    Hannah Gibbons
    Department of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
    Brain Res Mol Brain Res 110:63-75. 2003
    ..In contrast, LPS induced cyclooxygenase-2 (COX-2) to higher levels under hypothermic conditions. These results show that hypothermia selectively suppresses iNOS in microglia...