David R Murdoch

Summary

Affiliation: University of Otago
Country: New Zealand

Publications

  1. doi request reprint Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the VIDARIS randomized controlled trial
    David R Murdoch
    Department of Pathology, University of Otago, Christchurch, PO Box 4345, Christchurch 8011, New Zealand
    JAMA 308:1333-9. 2012
  2. doi request reprint Laboratory methods for determining pneumonia etiology in children
    David R Murdoch
    Department of Pathology, University of Otago, Christchurch, New Zealand
    Clin Infect Dis 54:S146-52. 2012
  3. doi request reprint Medical microbiology: laboratory diagnosis of invasive pneumococcal disease
    Anja M Werno
    Department of Microbiology, Canterbury Health Laboratories, University of Otago, Christchurch, New Zealand
    Clin Infect Dis 46:926-32. 2008
  4. ncbi request reprint Molecular genetic methods in the diagnosis of lower respiratory tract infections
    David R Murdoch
    Department of Pathology, Christchurch School of Medicine and Health Sciences, and Microbiology Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    APMIS 112:713-27. 2004
  5. ncbi request reprint Viral etiology of acute respiratory tract infections in children presenting to hospital: role of polymerase chain reaction and demonstration of multiple infections
    Lance C Jennings
    Microbiology Unit, Canterbury Health Laboratories, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
    Pediatr Infect Dis J 23:1003-7. 2004
  6. pmc Differentiation of Streptococcus pneumoniae from nonpneumococcal streptococci of the Streptococcus mitis group by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    Anja M Werno
    Microbiology Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    J Clin Microbiol 50:2863-7. 2012
  7. pmc Corynebacterium accolens-associated pelvic osteomyelitis
    Jenny S J Wong
    Department of Microbiology, Canterbury Health Laboratories, P O Box 151, Christchurch 8011, New Zealand
    J Clin Microbiol 48:654-5. 2010
  8. doi request reprint Emerging advances in rapid diagnostics of respiratory infections
    David R Murdoch
    Department of Pathology, University of Otago Christchurch, Christchurch 8140, New Zealand
    Infect Dis Clin North Am 24:791-807. 2010
  9. doi request reprint Outpatient intravenous treatment for infective endocarditis: safety, effectiveness and one-year outcomes
    Matthew R Amodeo
    Department of Microbiology, Canterbury Health Laboratories, Corner Hagley Ave and Tuam Street, Christchurch 8011, New Zealand
    J Infect 59:387-93. 2009
  10. doi request reprint Association between pneumococcal load and disease severity in adults with pneumonia
    Anja M Werno
    Microbiology Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    J Med Microbiol 61:1129-35. 2012

Collaborators

Detail Information

Publications31

  1. doi request reprint Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the VIDARIS randomized controlled trial
    David R Murdoch
    Department of Pathology, University of Otago, Christchurch, PO Box 4345, Christchurch 8011, New Zealand
    JAMA 308:1333-9. 2012
    ..However, results of clinical trials of vitamin D supplementation have been inconclusive...
  2. doi request reprint Laboratory methods for determining pneumonia etiology in children
    David R Murdoch
    Department of Pathology, University of Otago, Christchurch, New Zealand
    Clin Infect Dis 54:S146-52. 2012
    ..Pneumonia diagnostics are evolving, and it is also a priority of PERCH to collect and archive specimens for future testing by promising diagnostic methods that are currently under development...
  3. doi request reprint Medical microbiology: laboratory diagnosis of invasive pneumococcal disease
    Anja M Werno
    Department of Microbiology, Canterbury Health Laboratories, University of Otago, Christchurch, New Zealand
    Clin Infect Dis 46:926-32. 2008
    ..There is an urgent need for improved diagnostic tests for pneumococcal disease--especially tests that are suitable for use in underresourced countries...
  4. ncbi request reprint Molecular genetic methods in the diagnosis of lower respiratory tract infections
    David R Murdoch
    Department of Pathology, Christchurch School of Medicine and Health Sciences, and Microbiology Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    APMIS 112:713-27. 2004
    ..Further work is required to better characterize the role of molecular diagnostic tests for diagnosing lower respiratory tract infections, and to develop standard assays that can be readily adopted by routine diagnostic laboratories...
  5. ncbi request reprint Viral etiology of acute respiratory tract infections in children presenting to hospital: role of polymerase chain reaction and demonstration of multiple infections
    Lance C Jennings
    Microbiology Unit, Canterbury Health Laboratories, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
    Pediatr Infect Dis J 23:1003-7. 2004
    ..Viral lower respiratory tract infections are a leading cause of hospitalization for young children...
  6. pmc Differentiation of Streptococcus pneumoniae from nonpneumococcal streptococci of the Streptococcus mitis group by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    Anja M Werno
    Microbiology Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    J Clin Microbiol 50:2863-7. 2012
    ..The findings of this study suggest that it is possible to distinguish different species of the S. mitis group by close analysis of their mass peak profiles...
  7. pmc Corynebacterium accolens-associated pelvic osteomyelitis
    Jenny S J Wong
    Department of Microbiology, Canterbury Health Laboratories, P O Box 151, Christchurch 8011, New Zealand
    J Clin Microbiol 48:654-5. 2010
    ..Corynebacterium accolens is a rare human pathogen. We encountered a case of C. accolens isolated from a thigh collection in a man with osteomyelitis of the adjacent pubic symphysis...
  8. doi request reprint Emerging advances in rapid diagnostics of respiratory infections
    David R Murdoch
    Department of Pathology, University of Otago Christchurch, Christchurch 8140, New Zealand
    Infect Dis Clin North Am 24:791-807. 2010
    ..New approaches for respiratory pathogen detection are needed, and breath analysis is an exciting area with enormous potential...
  9. doi request reprint Outpatient intravenous treatment for infective endocarditis: safety, effectiveness and one-year outcomes
    Matthew R Amodeo
    Department of Microbiology, Canterbury Health Laboratories, Corner Hagley Ave and Tuam Street, Christchurch 8011, New Zealand
    J Infect 59:387-93. 2009
    ..To describe the use and outcomes of outpatient antimicrobial therapy (OPAT) for infective endocarditis (IE) within the Canterbury region of New Zealand over an 8 year period...
  10. doi request reprint Association between pneumococcal load and disease severity in adults with pneumonia
    Anja M Werno
    Microbiology Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    J Med Microbiol 61:1129-35. 2012
    ..Further work is needed to determine whether measuring pneumococcal load in respiratory specimens from adults will differentiate colonization from coincidental carriage...
  11. doi request reprint Detection of 2-pentylfuran in the breath of patients with Aspergillus fumigatus
    Stephen T Chambers
    Department of Pathology, University of Otago Christchurch, Christchurch, New Zealand
    Med Mycol 47:468-76. 2009
    ..As 2-PF is not normally found in human breath its presence may reflect the active metabolism of A. fumigatus in the airways and form the basis of a new diagnostic breath test for Aspergillus infection...
  12. pmc Characteristics of Streptococcus pseudopneumoniae isolated from purulent sputum samples
    Elaine R Keith
    Microbiology Unit, Canterbury Health Laboratories, P O Box 151, Christchurch, New Zealand
    J Clin Microbiol 44:923-7. 2006
    ..67 to 20.11) or exacerbation of COPD (OR, 6.5; 95% CI, 2.61 to 16.20). Further research is needed to better characterize the epidemiology of S. pseudopneumoniae colonization and the role of S. pseudopneumoniae in COPD and other diseases...
  13. ncbi request reprint The rapid evaluation of bacterial growth and antibiotic susceptibility in blood cultures by selected ion flow tube mass spectrometry
    Randall A Allardyce
    Department of Surgery, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Diagn Microbiol Infect Dis 55:255-61. 2006
    ..05). These results suggest incorporating SIFT-MS detection of microbial VOCs as a sensitive method for bacterial detection, identification, and determination of antibiotic susceptibility in a conventional blood culture system...
  14. doi request reprint Association of respiratory virus activity and environmental factors with the incidence of invasive pneumococcal disease
    David R Murdoch
    Department of Pathology, University of Otago Christchurch, P O Box 4345, Christchurch 8011, New Zealand
    J Infect 58:37-46. 2009
    ..To correlate the incidence rate of invasive pneumococcal disease (IPD) with fluctuations in respiratory virus activity and environmental factors in Christchurch, New Zealand...
  15. doi request reprint Comparison of four multiplex PCR assays for the detection of viral pathogens in respiratory specimens
    Trevor P Anderson
    Microbiology Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    J Virol Methods 191:118-21. 2013
    ..Other issues, such as through-put, technical requirements and cost, are likely to be as important for making a decision about which of these assays to use given their comparative performance...
  16. ncbi request reprint Nucleic acid amplification tests for the diagnosis of pneumonia
    David R Murdoch
    Microbiology Unit, Canterbury Health Laboratories, and Department of Pathology, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand
    Clin Infect Dis 36:1162-70. 2003
    ..Further work is required to better characterize the role of PCR versus the role of other tests for diagnosing pneumonia and to develop standard PCR assays that can be readily adopted by routine diagnostic laboratories...
  17. pmc Failure to genotype herpes simplex virus by real-time PCR assay and melting curve analysis due to sequence variation within probe binding sites
    Trevor P Anderson
    Microbiology Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    J Clin Microbiol 41:2135-7. 2003
    ..Sequence analysis showed that these strains had base-pair mismatches over the probe binding sites. An alternative assay is required to type such atypical isolates...
  18. doi request reprint Microbiological patterns in sepsis: what happened in the last 20 years?
    David R Murdoch
    Department of Pathology, University of Otago, P O Box 4345, Christchurch, New Zealand
    Int J Antimicrob Agents 34:S5-8. 2009
    ..The microbiological pattern of sepsis has also been influenced by the rise in prevalence of HIV infection in many regions...
  19. ncbi request reprint Comparison of the NOW Influenza A & B, NOW Flu A, NOW Flu B, and Directigen Flu A+B assays, and immunofluorescence with viral culture for the detection of influenza A and B viruses
    Marita Smit
    Canterbury Health Laboratories, Christchurch, New Zealand
    Diagn Microbiol Infect Dis 57:67-70. 2007
    ..The use of nasopharyngeal samples for all rapid detection methods should be strongly encouraged...
  20. pmc Recurrent breast abscess caused by Gordonia bronchialis in an immunocompetent patient
    Anja M Werno
    Microbiology Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    J Clin Microbiol 43:3009-10. 2005
    ..We present the first reported case of a recurrent breast infection caused by Gordonia bronchialis. The infection occurred in a 43-year-old immunocompetent female, and species level identification was obtained with 16S rRNA sequencing...
  21. pmc Campylobacter fetus-associated epidural abscess and bacteremia
    Jenny S J Wong
    Department of Microbiology, Canterbury Health Laboratories, Christchurch, New Zealand
    J Clin Microbiol 47:857-8. 2009
    ..Campylobacter fetus has been isolated as an infrequent cause of abscesses. We report a case of Campylobacter fetus epidural abscess and bacteremia in a debilitated elderly man who had a fatal outcome...
  22. ncbi request reprint Comparison of PCR-ELISA and galactomannan detection for the diagnosis of invasive aspergillosis
    Jennifer M Scotter
    Microbiology Unit, Canterbury Health Laboratories, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand
    Pathology 37:246-53. 2005
    ..To compare PCR with galactomannan antigen detection for the diagnosis of invasive aspergillosis (IA)...
  23. doi request reprint Assessment of potential causes of falsely positive Mycobacterium tuberculosis breath test
    Amy Scott-Thomas
    Department of Pathology, University of Otago, Christchurch, PO Box 4345, Christchurch 8140, New Zealand Electronic address
    Tuberculosis (Edinb) 93:312-7. 2013
    ..These results justify further clinical studies to further explore these markers as specific indicators of M. tuberculosis infection...
  24. doi request reprint Immune reactivity of four monoclonal and two polyclonal antibodies raised against recombinant pneumococcal surface adhesin A
    Anja M Werno
    Microbiology Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    Hybridoma (Larchmt) 31:168-75. 2012
    ..The specificity of the four MAbs appears to be high as they only recognized S. pneumoniae and S. pseudopneumoniae. However, further testing of closely related streptococcal species is necessary to confirm this finding...
  25. doi request reprint Atypical pneumonia--time to breathe new life into a useful term?
    David R Murdoch
    Department of Pathology, University of Otago, Christchurch, New Zealand
    Lancet Infect Dis 9:512-9. 2009
    ..We need to return to the original meaning of atypical pneumonia and restrict its use to describe pneumonia that is truly unusual in clinical presentation, epidemiology, or both...
  26. ncbi request reprint Successful antimicrobial therapy and implant retention for streptococcal infection of prosthetic joints
    Richard J Everts
    Department of Infectious Diseases, Christchurch Hospital, Christchurch, New Zealand
    ANZ J Surg 74:210-4. 2004
    ..Streptococci cause up to 20% of prosthetic joint infections but this has received little attention in the published literature...
  27. pmc Comparison of the Mycoplasma Duo test with PCR for detection of ureaplasma species in endotracheal aspirates from premature infants
    Fook Choe Cheah
    Department of Pathology, Christchurch School of Medicine and Health Sciences, University of Otago, P O Box 4345, Christchurch, New Zealand
    J Clin Microbiol 43:509-10. 2005
    ..in endotracheal aspirates from 60 premature neonates. The overall agreement between the two tests was 96%. The Mycoplasma Duo assay is a useful alternative to culture and PCR for detection of neonatal Ureaplasma infection...
  28. pmc Evaluation of a PCR assay for detection of Streptococcus pneumoniae in respiratory and nonrespiratory samples from adults with community-acquired pneumonia
    David R Murdoch
    Microbiology Unit, Canterbury Health Laboratories, Christchurch, New Zealand
    J Clin Microbiol 41:63-6. 2003
    ..We conclude that the pneumolysin PCR assay adds little to existing diagnostic tests for S. pneumoniae and is unable to distinguish colonization from infection when respiratory samples are tested...
  29. ncbi request reprint Detection of volatile metabolites produced by bacterial growth in blood culture media by selected ion flow tube mass spectrometry (SIFT-MS)
    Randall A Allardyce
    Department of Surgery, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand
    J Microbiol Methods 65:361-5. 2006
    ..Pseudomonas aeruginosa, Streptococcus pneumoniae, Escherichia coli, Staphylococcus aureus and Neisseria meningitidis growth and trace gas patterns were detected from 10 colony forming units after 6 h...
  30. ncbi request reprint The etiology of febrile illness in adults presenting to Patan hospital in Kathmandu, Nepal
    David R Murdoch
    Department of Pathology, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
    Am J Trop Med Hyg 70:670-5. 2004
    ..Given the lack of reliable clinical predictors, the development of cheap and accurate diagnostic tests are likely to be of great clinical utility in this setting...
  31. doi request reprint Fusobacterial infections: clinical spectrum and incidence of invasive disease
    Paul J Huggan
    Department of Infectious Diseases, Christchurch Hospital, Riccarton Avenue, Christchurch 8011, New Zealand
    J Infect 57:283-9. 2008
    ..Clinically significant infections caused by members of the genus Fusobacterium are rare. We sought to describe the spectrum of clinical disease and epidemiology of these conditions presenting to an acute hospital over a five year period...