Research Topics
Genomes and Genes
| Angharad R MorganSummaryAffiliation: University of Auckland Country: New Zealand Publications
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Detail Information
Publications
Genetic variation within TLR10 is associated with Crohn's disease in a New Zealand populationAngharad R Morgan
Discipline of Nutrition, The University of Auckland, Auckland, New Zealand
Hum Immunol 73:416-20. 2012..This study provides evidence to suggest that genetic variation in TLR10 plays a role in interindividual differences in CD susceptibility and clinical outcome...
Metallothionein genes: no association with Crohn's disease in a New Zealand populationAngharad R Morgan
Discipline of Nutrition, FMHS, The University of Auckland, Auckland, New Zealand
J Negat Results Biomed 11:8. 2012..We did not find any evidence of association for MT genetic variation with CD. The lack of association indicates that genetic variants in the MT genes do not play a significant role in predisposing to CD in the New Zealand population...
Genetic adult lactase persistence is associated with risk of Crohn's Disease in a New Zealand populationDeborah J Nolan
Smart Foods Centre, University of Wollongong, Northfields Ave, Wollongong, New South Wales, Australia
BMC Res Notes 3:339. 2010..abstract:..
Genetic variations in matrix metalloproteinases may be associated with increased risk of ulcerative colitisAngharad R Morgan
Discipline of Nutrition, FMHS, The University of Auckland, Auckland, New Zealand
Hum Immunol 72:1117-27. 2011..Further studies are needed in other cohorts to determine the robustness of these observations in different populations...
Association analysis of 3p21 with Crohn's disease in a New Zealand populationAngharad R Morgan
Discipline of Nutrition, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
Hum Immunol 71:602-9. 2010..The results from this study support the accumulating evidence that suggests the 3p21 region is a CD-associated locus, although it remains unclear which is the causative SNP and/or gene...
PTPN2 but not PTPN22 is associated with Crohn's disease in a New Zealand populationA R Morgan
Discipline of Nutrition, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
Tissue Antigens 76:119-25. 2010..There was no evidence for an association with PTPN22...
Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative studyAngharad R Morgan
Discipline of Nutrition, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
BMC Med Genet 11:125. 2010..However, in a large proportion of SGA, no underlying cause is evident, and these individuals may have a larger genetic contribution...
Analysis of MMP2 promoter polymorphisms in childhood obesityAngharad R Morgan
Discipline of Nutrition, FMHS, The University of Auckland, New Zealand
BMC Res Notes 4:253. 2011..abstract:..
Determining genetic risk factors for pediatric type 2 diabetesAngharad R Morgan
Department of Nutrition, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Grafton, Auckland 1142, New Zealand
Curr Diab Rep 12:88-92. 2012..The review concludes with a discussion of future research that will be required for determining genetic risk factors for pediatric T2D...
Reduced genetic influence on childhood obesity in small for gestational age childrenDug Yeo Han
Discipline of Nutrition, FM and HS, The University of Auckland, Auckland, New Zealand
BMC Med Genet 14:10. 2013....
Selenium, selenoprotein genes and Crohn's disease in a case-control population from Auckland, New ZealandLiljana Gentschew
Discipline of Nutrition, FM and HS, University of Auckland, New Zealand
Nutrients 4:1247-59. 2012..These three SNPs have not been reported elsewhere as being significantly associated with selenium or CD. It is unclear as to whether lower selenium levels are a cause or an effect of the disease...
The effect of IL-10 genetic variation and interleukin 10 serum levels on Crohn's disease susceptibility in a New Zealand populationAlice H Wang
Discipline of Nutrition, FMHS, The University of Auckland, Auckland, New Zealand
Hum Immunol 72:431-5. 2011....
Genetic factors in chronic inflammation: single nucleotide polymorphisms in the STAT-JAK pathway, susceptibility to DNA damage and Crohn's disease in a New Zealand populationLynnette R Ferguson
Discipline of Nutrition, FM and HS, The University of Auckland, Auckland, New Zealand Nutrigenomics New Zealand, New Zealand
Mutat Res 690:108-15. 2010..It will be of interest to follow up CD patients carrying either JAK2 or STAT3 risk alleles for development of further secondary effects, including cancer...
IL23R and IL12B SNPs and Haplotypes Strongly Associate with Crohn's Disease Risk in a New Zealand PopulationLynnette R Ferguson
Discipline of Nutrition, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, 1142, New Zealand
Gastroenterol Res Pract 2010:539461. 2010..Certain haplotypes very strongly modified risk. There was evidence for interactions of IL-23R variants with the NOD2 wild-type (d/d) genotype. Down-regulating the function of the IL-23R gene may decrease CD risk in the normal population...
DNase1: No Association with Crohn's Disease in a New Zealand PopulationAngharad R Morgan
Discipline of Nutrition, Faculty of Medical and Health Sciences FMHS, The University of Auckland, 85 Park Road, Grafton, 1142 Auckland, New Zealand
ISRN Gastroenterol 2012:826323. 2012..The lack of association indicates that DNase1 does not play a significant role in predisposing to CD in the New Zealand population...
Association Analysis of ULK1 with Crohn's Disease in a New Zealand PopulationAngharad R Morgan
Department of Nutrition, Faculty of Medical and Health Sciences, The University of Auckland, Grafton, Auckland 1142, New Zealand
Gastroenterol Res Pract 2012:715309. 2012..The findings of this study provide evidence to suggest that genetic variation in ULK1 may play a role in interindividual differences in CD susceptibility and clinical outcome...
The catechol-O-methyltransferase (COMT) Val158Met polymorphism moderates the effect of antenatal stress on childhood behavioural problems: longitudinal evidence across multiple agesJohn M D Thompson
Department of Paediatrics, FM and HS, The University of Auckland, Auckland, New Zealand
Dev Med Child Neurol 54:148-54. 2012..The functional polymorphism Val158Met in the catechol-O-methyltransferase (COMT) gene was analysed to determine its association with maternal stress and childhood total difficulties...
