Fiona M McQueen

Summary

Affiliation: University of Auckland
Country: New Zealand

Publications

  1. ncbi request reprint Imaging in the crystal arthropathies
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, 85 Park Road, Grafton, Auckland 1023, New Zealand Auckland District Health Board, Department of Rheumatology, Greenlane Clinical Centre, 214 Green Lane West, Auckland 1051, New Zealand Electronic address
    Rheum Dis Clin North Am 40:231-49. 2014
  2. doi request reprint Is rheumatoid arthritis a B-cell haematological disease with a predilection for the joints? Following the B cell thread to its logical conclusion
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, FMHS, University of Auckland, Auckland, New Zealand Department of Haematology, Middlemore Hospital, Counties Manakau District Health Board, Auckland, New Zealand Electronic address
    Med Hypotheses 82:266-70. 2014
  3. doi request reprint Bone erosions in patients with chronic gouty arthropathy are associated with tophi but not bone oedema or synovitis: new insights from a 3 T MRI study
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland 1023, New Zealand
    Rheumatology (Oxford) 53:95-103. 2014
  4. ncbi request reprint Insights into rheumatoid arthritis from use of MRI
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand
    Curr Rheumatol Rep 16:388. 2014
  5. doi request reprint Imaging in early rheumatoid arthritis
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand Electronic address
    Best Pract Res Clin Rheumatol 27:499-522. 2013
  6. doi request reprint New insights into an old disease: advanced imaging in the diagnosis and management of gout
    Fiona Marion McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, 85 Park Rd, Grafton, Auckland 1023, New Zealand
    Postgrad Med J 89:87-93. 2013
  7. doi request reprint Mechanisms of joint damage in gout: evidence from cellular and imaging studies
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, Park Road, Grafton, Auckland 1023, New Zealand
    Nat Rev Rheumatol 8:173-81. 2012
  8. pmc Imaging in gout--what can we learn from MRI, CT, DECT and US?
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medicine and Health Sciences, University of Auckland, 85 Park Road, Grafton, Auckland 1023, New Zealand
    Arthritis Res Ther 13:246. 2011
  9. doi request reprint A B cell explanation for autoimmune disease: the forbidden clone returns
    Fiona McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, 85 Park Road, Grafton, Auckland, New Zealand
    Postgrad Med J 88:226-33. 2012
  10. doi request reprint B cell lymphoproliferation and organ-directed self-recognition to explain autoimmunity: back to the past
    Fiona McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, P O Box 92019, Auckland, New Zealand
    Med Hypotheses 75:328-33. 2010

Collaborators

Detail Information

Publications73

  1. ncbi request reprint Imaging in the crystal arthropathies
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, 85 Park Road, Grafton, Auckland 1023, New Zealand Auckland District Health Board, Department of Rheumatology, Greenlane Clinical Centre, 214 Green Lane West, Auckland 1051, New Zealand Electronic address
    Rheum Dis Clin North Am 40:231-49. 2014
    ..The type of imaging used needs to be adapted to the clinical question of relevance. ..
  2. doi request reprint Is rheumatoid arthritis a B-cell haematological disease with a predilection for the joints? Following the B cell thread to its logical conclusion
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, FMHS, University of Auckland, Auckland, New Zealand Department of Haematology, Middlemore Hospital, Counties Manakau District Health Board, Auckland, New Zealand Electronic address
    Med Hypotheses 82:266-70. 2014
    ..The erosions of RA would have parallels with the lytic lesions of MM but autoantigen targeting dictates that erosions occur at joint margins. This theory is discussed from rheumatologic and haematologic perspectives. ..
  3. doi request reprint Bone erosions in patients with chronic gouty arthropathy are associated with tophi but not bone oedema or synovitis: new insights from a 3 T MRI study
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland 1023, New Zealand
    Rheumatology (Oxford) 53:95-103. 2014
    ..Our aims in this prospective 3 T MRI study were to investigate the frequency of these features in gout and determine their relation to one another...
  4. ncbi request reprint Insights into rheumatoid arthritis from use of MRI
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand
    Curr Rheumatol Rep 16:388. 2014
    ..Finally, recent clinical trials are reviewed, in which MRI outcome measures are being established as sensitive response markers. ..
  5. doi request reprint Imaging in early rheumatoid arthritis
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand Electronic address
    Best Pract Res Clin Rheumatol 27:499-522. 2013
    ..Thus, the clinician needs to choose the most relevant and reliable imaging test, while also striving to minimise patient discomfort, radiation burden and economic impact. ..
  6. doi request reprint New insights into an old disease: advanced imaging in the diagnosis and management of gout
    Fiona Marion McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, 85 Park Rd, Grafton, Auckland 1023, New Zealand
    Postgrad Med J 89:87-93. 2013
    ..This review discusses the clinical and research applications of advanced imaging in gout with particular focus on diagnosis and monitoring of joint inflammation and damage...
  7. doi request reprint Mechanisms of joint damage in gout: evidence from cellular and imaging studies
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, Park Road, Grafton, Auckland 1023, New Zealand
    Nat Rev Rheumatol 8:173-81. 2012
    ..Imaging is also increasingly being used to monitor the progression of joint damage and regression of tophi with effective urate-lowering therapy...
  8. pmc Imaging in gout--what can we learn from MRI, CT, DECT and US?
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medicine and Health Sciences, University of Auckland, 85 Park Road, Grafton, Auckland 1023, New Zealand
    Arthritis Res Ther 13:246. 2011
    ..Imaging can also provide outcome measures, such as change in tophus volume, for monitoring the response to urate-lowering therapy and this is an important application in the clinical trial setting...
  9. doi request reprint A B cell explanation for autoimmune disease: the forbidden clone returns
    Fiona McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, 85 Park Road, Grafton, Auckland, New Zealand
    Postgrad Med J 88:226-33. 2012
    ....
  10. doi request reprint B cell lymphoproliferation and organ-directed self-recognition to explain autoimmunity: back to the past
    Fiona McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, P O Box 92019, Auckland, New Zealand
    Med Hypotheses 75:328-33. 2010
    ..There is considerable evidence that autoimmune diseases could be indolent lymphoproliferative disorders of B-cell origin, extending the forbidden clone hypothesis first proposed in the 1950s...
  11. ncbi request reprint MRI in psoriatic arthritis: insights into pathogenesis and treatment response
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, Private Bag 92019, Auckland, New Zealand
    Curr Rheumatol Rep 10:303-10. 2008
    ..Finally, MRI can be used to score and quantify these pathologic features, providing a sensitive tool with which to evaluate disease progression...
  12. doi request reprint Zoledronic acid does not reduce MRI erosive progression in PsA but may suppress bone oedema: the Zoledronic Acid in Psoriatic Arthritis (ZAPA) Study
    Fiona McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand
    Ann Rheum Dis 70:1091-4. 2011
    ..The effect of zoledronic acid (ZA) on articular bone in patients with psoriatic arthritis (PsA) was investigated using MRI...
  13. doi request reprint Assessment of cartilage loss at the wrist in rheumatoid arthritis using a new MRI scoring system
    Fiona McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, New Zealand
    Ann Rheum Dis 69:1971-5. 2010
    ..To develop and test an MRI cartilage scoring system for use at the wrist in rheumatoid arthritis (RA)...
  14. doi request reprint Measuring bone erosion and edema in rheumatoid arthritis: a comparison of manual segmentation and RAMRIS methods
    Angela R Crowley
    Department of Rheumatology, Greenlane Clinical Centre, Auckland District Health Board, Auckland, New Zealand
    J Magn Reson Imaging 33:364-71. 2011
    ..To investigate the reliability, feasibility, and validity of a computer-assisted manual segmentation (outlining) technique for measuring magnetic resonance imaging (MRI) bone erosion and edema at the wrist in rheumatoid arthritis (RA)...
  15. ncbi request reprint The MRI view of synovitis and tenosynovitis in inflammatory arthritis: implications for diagnosis and management
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand
    Ann N Y Acad Sci 1154:21-34. 2009
    ..In the long term, an overall score of inflammation incorporating synovitis, tenosynovitis, and bone edema may be a more useful MRI predictor of aggressive erosive disease...
  16. ncbi request reprint Will Jill come tumbling after? The case for a JAK2-type mutation as a prequel to the connective tissue disorders
    Fiona M McQueen
    Dept of Molecular Medicine and Pathology, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand
    Med Hypotheses 73:651-4. 2009
    ..The success of B cell depletion therapy in rheumatoid arthritis and systemic lupus erythematosus is also strong circumstantial evidence for this hypothesis...
  17. pmc What is the fate of erosions in early rheumatoid arthritis? Tracking individual lesions using x rays and magnetic resonance imaging over the first two years of disease
    F M McQueen
    Department of Molecular Medicine, Auckland School of Medicine, Auckland University, New Zealand
    Ann Rheum Dis 60:859-68. 2001
    ..To investigate the progression of erosions at sites within the carpus, in patients with early rheumatoid arthritis (RA), using magnetic resonance imaging (MRI) and plain radiology over a two year period...
  18. ncbi request reprint Bone edema scored on magnetic resonance imaging scans of the dominant carpus at presentation predicts radiographic joint damage of the hands and feet six years later in patients with rheumatoid arthritis
    Fiona M McQueen
    Auckland District Health Board and Auckland University, Auckland, New Zealand
    Arthritis Rheum 48:1814-27. 2003
    ..These features are visible before radiographic joint damage occurs. We sought to examine whether MRI of one body region (the wrist) can be used to predict whole-body radiography scores reflecting joint damage at 6 years...
  19. ncbi request reprint Magnetic resonance imaging evidence of tendinopathy in early rheumatoid arthritis predicts tendon rupture at six years
    Fiona McQueen
    University of Auckland and Auckland District Health Board, Auckland, New Zealand
    Arthritis Rheum 52:744-51. 2005
    ..To determine whether magnetic resonance imaging (MRI) evidence of tendinopathy in early rheumatoid arthritis (RA) could be used to predict the course of tendon involvement in later disease and specifically the risk of tendon rupture...
  20. pmc Magnetic resonance imaging in psoriatic arthritis: a review of the literature
    Fiona McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medicine and Health Sciences, University of Auckland, Auckland, New Zealand
    Arthritis Res Ther 8:207. 2006
    ..Comparisons have been drawn with the more extensive literature describing the MRI features of rheumatoid arthritis and ankylosing spondylitis...
  21. pmc What is MRI bone oedema in rheumatoid arthritis and why does it matter?
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medicine and Health Sciences, University of Auckland, Park Rd, Auckland, New Zealand
    Arthritis Res Ther 8:222. 2006
    ..There is emerging evidence from animal models that such an infiltrate corresponds with MRI bone oedema, pointing towards the bone marrow as a site for important pathology driving joint damage in rheumatoid arthritis...
  22. ncbi request reprint Developing a magnetic resonance imaging scoring system for peripheral psoriatic arthritis
    Fiona McQueen
    Department of Rheumatology, Auckland University, Auckland, New Zealand
    J Rheumatol 34:859-61. 2007
    ..Measures to improve reliability for future exercises will include reviewing definitions of pathological features and prior reader calibration...
  23. pmc High-grade MRI bone oedema is common within the surgical field in rheumatoid arthritis patients undergoing joint replacement and is associated with osteitis in subchondral bone
    F M McQueen
    Department of Molecular Medicine and Pathology, Faculty of Medicine and Health Sciences, University of Auckland, Park Rd, Private Bag 92019 Auckland, New Zealand
    Ann Rheum Dis 66:1581-7. 2007
    ..We studied MRI scans from RA patients undergoing surgery, seeking to identify regions of bone oedema and examine its histopathological equivalent in resected bone...
  24. doi request reprint Monosodium urate monohydrate crystals inhibit osteoblast viability and function: implications for development of bone erosion in gout
    Ashika Chhana
    Bone Research Group, Department of Medicine, University of Auckland, Auckland, New Zealand
    Ann Rheum Dis 70:1684-91. 2011
    ..Bone erosion is a common manifestation of chronic tophaceous gout...
  25. ncbi request reprint Zoledronate for prevention of bone erosion in tophaceous gout: a randomised, double-blind, placebo-controlled trial
    Nicola Dalbeth
    Department of Medicine, University of Auckland, Auckland, New Zealand
    Ann Rheum Dis 73:1044-51. 2014
    ..The osteoclast has been implicated in development of bone erosion in gout. The aim of this study was to determine whether zoledronate, a potent antiosteoclast drug, influences bone erosion in people with tophaceous gout...
  26. doi request reprint Effects of skim milk powder enriched with glycomacropeptide and G600 milk fat extract on frequency of gout flares: a proof-of-concept randomised controlled trial
    Nicola Dalbeth
    Bone and Joint Research Group, Department of Medicine, University of Auckland, Auckland, New Zealand
    Ann Rheum Dis 71:929-34. 2012
    ..The aim of this proof-of-concept clinical trial was to test the hypothesis that daily intake of skim milk powder (SMP) enriched with GMP and G600 can prevent gout flares...
  27. doi request reprint The experience and impact of gout in Māori and Pacific people: a prospective observational study
    Nicola Dalbeth
    University of Auckland, Auckland, New Zealand
    Clin Rheumatol 32:247-51. 2013
    ..Māori and Pacific ethnicity should be recognised as a prognostic factor for more severe outcomes in this disease, and intensive efforts should be made to work with these patients to control serum urate and prevent flares...
  28. doi request reprint Nail disease in psoriatic arthritis: distal phalangeal bone edema detected by magnetic resonance imaging predicts development of onycholysis and hyperkeratosis
    Nicola Dalbeth
    Bone Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Grafton, Auckland, New Zealand
    J Rheumatol 39:841-3. 2012
    ..To examine the association between magnetic resonance imaging (MRI) features of distal phalanx (DP) disease and the progression of nail pathology in psoriatic arthritis (PsA)...
  29. pmc MRI bone oedema scores are higher in the arthritis mutilans form of psoriatic arthritis and correlate with high radiographic scores for joint damage
    Yu M Tan
    Department of Molecular Medicine and Pathology, University of Auckland, Park Road, Auckland 1010, New Zealand
    Arthritis Res Ther 11:R2. 2009
    ..The aim of this study was to investigate the magnetic resonance imaging (MRI) features of bone disease in the arthritis mutilans (AM) form of psoriatic arthritis (PsA)...
  30. pmc Circulating mediators of bone remodeling in psoriatic arthritis: implications for disordered osteoclastogenesis and bone erosion
    Nicola Dalbeth
    Department of Medicine, University of Auckland, Auckland 1010, New Zealand
    Arthritis Res Ther 12:R164. 2010
    ..The aim of this study was to examine the role of soluble mediators of bone remodeling within the circulation of patients with PsA...
  31. doi request reprint Quantifying bone marrow edema in the rheumatoid cervical spine using magnetic resonance imaging
    Ravi Suppiah
    Department of Rheumatology and Department of Radiology, Auckland District Health Board, Auckland, United Kingdom
    J Rheumatol 37:1626-32. 2010
    ....
  32. ncbi request reprint Cellular characterization of the gouty tophus: a quantitative analysis
    Nicola Dalbeth
    University of Auckland, Auckland, New Zealand
    Arthritis Rheum 62:1549-56. 2010
    ..To characterize the cellular architecture of the tophus and to determine the presence of cytokines implicated in the initiation and resolution of gouty inflammation...
  33. doi request reprint Assessment of tophus size: a comparison between physical measurement methods and dual-energy computed tomography scanning
    Nicola Dalbeth
    Department of Medicine, University of Auckland, Auckland, New Zealand
    J Clin Rheumatol 18:23-7. 2012
    ..Dual-energy computed tomography (DECT) has recently been described as a sensitive method to detect urate deposits in patients with gout...
  34. doi request reprint Illness perceptions in patients with gout and the relationship with progression of musculoskeletal disability
    Nicola Dalbeth
    University of Auckland, New Zealand
    Arthritis Care Res (Hoboken) 63:1605-12. 2011
    ..Although suboptimal disease management has been reported in patients with gout, patients' perceptions of illness have not been systematically studied. The aim of this study was to examine illness perceptions in patients with gout...
  35. ncbi request reprint Exploratory study of radiographic change in patients with tophaceous gout treated with intensive urate-lowering therapy
    Nicola Dalbeth
    University of Auckland, Auckland, New Zealand
    Arthritis Care Res (Hoboken) 66:82-5. 2014
    ..Pegloticase leads to dramatic reductions in serum urate and subcutaneous tophi in treatment responders. The aim of this analysis was to examine whether profound urate lowering can alter radiographic findings in gout...
  36. ncbi request reprint Update on the OMERACT magnetic resonance imaging task force: research and future directions
    Philip G Conaghan
    From the Section of Musculoskeletal Disease, University of Leeds, and the UK National Institute for Health Research NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK Department of Molecular Medicine and Pathology, Faculty of Medicine and Health Sciences, University of Auckland, Auckland, New Zealand University of NSW, Sydney, Australia Spire Sciences LLC, San Francisco, California, USA Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway Department of Rheumatology, Pitie Salpetriere Hospital, APHP, Universite Paris 6 UPMC, Paris, France Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel Glostrup University Hospital, Copenhagen, Denmark Department of Rheumatology, Slagelse Hospital, Slagelse, Denmark Department of Radiology, Charite University Hospital, Berlin, Germany Department of Rheumatology, St George Hospital, University of NSW, Australia Department of Radiology, Chapel Allerton Hospital, Leeds, UK Medicine and Orthopaedics, University of California San Francisco, San Francisco, California, 1 Aspenlea Road
    J Rheumatol 41:383-5. 2014
    ..Optimizing the role of MRI as a robust biomarker and surrogate outcome remains a priority for this group. ..
  37. pmc Prescription and dosing of urate-lowering therapy, rather than patient behaviours, are the key modifiable factors associated with targeting serum urate in gout
    Nicola Dalbeth
    Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, 1023, New Zealand
    BMC Musculoskelet Disord 13:174. 2012
    ..However, many studies have reported low achievement of SU targets. The aim of this cross-sectional study was to examine the clinical and psychological factors associated with SU targets in patients with gout...
  38. doi request reprint Development of a computed tomography method of scoring bone erosion in patients with gout: validation and clinical implications
    Nicola Dalbeth
    Department of Medicine, University of Auckland, Grafton, Auckland, New Zealand
    Rheumatology (Oxford) 50:410-6. 2011
    ..To develop a method of scoring bone erosion in the feet of patients with gout using CT as an outcome measure for chronic gout studies, consistent with the components of the OMERACT filter...
  39. ncbi request reprint Interactions between tenocytes and monosodium urate monohydrate crystals: implications for tendon involvement in gout
    Ashika Chhana
    Bone and Joint Research Group, Department of Medicine, University of Auckland, Auckland, New Zealand
    Ann Rheum Dis 73:1737-41. 2014
    ..The aim of this study was to investigate the effects of monosodium urate monohydrate (MSU) crystals on tenocyte viability and function...
  40. doi request reprint Iterative development and reliability of the OMERACT hand osteoarthritis MRI scoring system
    Ida K Haugen
    From the Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway Department of Rheumatology, Copenhagen University Hospitals at Glostrup, Copenhagen, Denmark Department of Diagnostic Imaging, Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel Department of Molecular Medicine and Pathology, Faculty of Medicine and Health Sciences, University of Auckland, Auckland, New Zealand Department of Rheumatology, St George Hospital, Sydney, Australia St George Clinical School, University of New South Wales, Sydney, Australia Department of Rheumatology, Pitie Salpetriere Hospital, APHP, Universite Pierre et Marie Curie, Paris, France Departments of Radiology and Medicine, University of California San Francisco, San Francisco, CA, USA Synarc Inc, Newark, California, USA Spire Sciences Inc, Boca Raton, Florida, USA Leeds Institute of Rheumatic and Musculoskeletal Medicine USA Section of Musculoskeletal Disease, University of Leeds and UK National Institute for Health Research NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK
    J Rheumatol 41:386-91. 2014
    ..To develop and test the interreader reliability of the OMERACT Hand Osteoarthritis Magnetic Resonance Scoring System (HOAMRIS) for assessment of structural and inflammatory hand OA features in the interphalangeal joints...
  41. doi request reprint The Work Instability Scale predicts absenteeism in people with gout and suggests a higher risk for those in manual occupations
    William J Taylor
    Rehabilitation Teaching and Research Unit, Department of Medicine, University of Otago Wellington, Auckland, New Zealand
    J Clin Rheumatol 18:405-10. 2012
    ..Gout occurs in working-age people and may be associated with significant work disability. There are no longitudinal studies to examine risk factors for work disability in people with gout...
  42. doi request reprint Acute effect of milk on serum urate concentrations: a randomised controlled crossover trial
    Nicola Dalbeth
    Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand
    Ann Rheum Dis 69:1677-82. 2010
    ..The aims of this study were to determine the acute effects of milk ingestion on serum urate concentrations and examine the mechanisms of these effects...
  43. ncbi request reprint Determining a magnetic resonance imaging inflammatory activity acceptable state without subsequent radiographic progression in rheumatoid arthritis: results from a followup MRI study of 254 patients in clinical remission or low disease activity
    Frédérique Gandjbakhch
    From the Department of Rheumatology, Pitie Salpetriere Hospital, APHP, Universite Paris 6 UPMC, Paris, France Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and UK National Institute for Health Research NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK Department of Rheumatology, Slagelse Hospital, Slagelse, Denmark Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway Hull York Medical School, University of York, York, UK Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen, Denmark and Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark St George Hospital, University of NSW, Sydney, Australia King Christian X s Hospital for Rheumatic Diseases, University of Southern Denmark, Odense, Denmark and Department of Molecular Medicine and Pathology, Faculty of Medicine and Health Sciences, University of Auckland, Auckland, New Zealand
    J Rheumatol 41:398-406. 2014
    ....
  44. doi request reprint The effects of monosodium urate monohydrate crystals on chondrocyte viability and function: implications for development of cartilage damage in gout
    Ashika Chhana
    From the Bone and Joint Research Group, Department of Medicine and the Department of Orthopaedic Surgery, University of Auckland, Auckland and the Department of Histology, Waikato Hospital, Hamilton, New Zealand
    J Rheumatol 40:2067-74. 2013
    ..Cartilage damage is frequently observed in advanced destructive gout. The aim of our study was to investigate the effects of monosodium urate monohydrate (MSU) crystals on chondrocyte viability and function...
  45. doi request reprint Tendon involvement in the feet of patients with gout: a dual-energy CT study
    Nicola Dalbeth
    Bone and Joint Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    Ann Rheum Dis 72:1545-8. 2013
    ..To examine the frequency and patterns of monosodium urate (MSU) crystal deposition in tendons and ligaments in patients with gout using dual-energy CT (DECT)...
  46. pmc Tophus measurement as an outcome measure for clinical trials of chronic gout: progress and research priorities
    Nicola Dalbeth
    Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    J Rheumatol 38:1458-61. 2011
    ..Further information is also required regarding which method of physical measurement is best for use in future clinical trials. The need to develop and test a patient-reported outcome measure of tophus burden is also highlighted...
  47. doi request reprint Magnetic resonance imaging bone edema is not a major feature of gout unless there is concomitant osteomyelitis: 10-year findings from a high-prevalence population
    Yih Jia Poh
    Department of Rheumatology, Greenlane Clinical Centre, Auckland Mail Centre, Auckland 1142, New Zealand
    J Rheumatol 38:2475-81. 2011
    ..Magnetic resonance imaging (MRI) is commonly used in autoimmune inflammatory arthritis to define disease activity and damage, but its role in gout remains unclear. The aim of our study was to identify and describe the MRI features of gout...
  48. doi request reprint Identification of dairy fractions with anti-inflammatory properties in models of acute gout
    Nicola Dalbeth
    Bone Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Grafton, Auckland, New Zealand
    Ann Rheum Dis 69:766-9. 2010
    ..It was hypothesised that factors within dairy fractions inhibit the inflammatory response to monosodium urate monohydrate (MSU) crystals...
  49. doi request reprint Use of imaging to evaluate gout and other crystal deposition disorders
    Nicola Dalbeth
    University of Auckland, New Zealand
    Curr Opin Rheumatol 21:124-31. 2009
    ..This review summarizes recent advances in plain radiography and advanced imaging for gout, calcium pyrophosphate dihydrate crystal arthropathy and basic calcium phosphate crystal arthropathy...
  50. doi request reprint Imaging in gout: insights into the pathological features of disease
    Nicola Dalbeth
    Auckland Rheumatology Imaging Group, University of Auckland, Grafton, Auckland, New Zealand
    Curr Opin Rheumatol 24:132-8. 2012
    ..This review discusses recent research examining the role of imaging to assess the manifestations of disease...
  51. ncbi request reprint Enhanced osteoclastogenesis in patients with tophaceous gout: urate crystals promote osteoclast development through interactions with stromal cells
    Nicola Dalbeth
    University of Auckland, Grafton, Auckland, New Zealand
    Arthritis Rheum 58:1854-65. 2008
    ..To analyze cellular mechanisms of bone erosion in gout...
  52. doi request reprint Methods of tophus assessment in clinical trials of chronic gout: a systematic literature review and pictorial reference guide
    Nicola Dalbeth
    Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Grafton, Auckland, New Zealand
    Ann Rheum Dis 70:597-604. 2011
    ..To identify methods of tophus measurement for gout studies, summarise the properties of these methods and compile a detailed pictorial reference guide to demonstrate the methods...
  53. pmc MRI bone oedema predicts eight year tendon function at the wrist but not the requirement for orthopaedic surgery in rheumatoid arthritis
    S Zheng
    Department of Molecular Medicine, Auckland School of Medicine, Auckland University, Private Bag 92019, Auckland, New Zealand
    Ann Rheum Dis 65:607-11. 2006
    ..To investigate the role of early magnetic resonance imaging (MRI) of the wrist in predicting functional outcome in rheumatoid arthritis...
  54. ncbi request reprint Computed tomography measurement of tophus volume: comparison with physical measurement
    Nicola Dalbeth
    University of Auckland, Auckland, New Zealand
    Arthritis Rheum 57:461-5. 2007
    ..Computed tomography (CT) has high accuracy for tophus detection. This study assessed reliability of CT measurement of tophus volume and compared reproducibility of CT with physical measurement of tophus size...
  55. doi request reprint Functional and biomechanical characteristics of foot disease in chronic gout: A case-control study
    Keith Rome
    AUT University, Health and Rehabilitation Research Institute, Auckland, New Zealand
    Clin Biomech (Bristol, Avon) 26:90-4. 2011
    ..The aim of this study was to describe the effects of chronic gout upon function and selected biomechanical parameters associated with gait...
  56. doi request reprint Cellular characterisation of magnetic resonance imaging bone oedema in rheumatoid arthritis; implications for pathogenesis of erosive disease
    N Dalbeth
    Bone Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand
    Ann Rheum Dis 68:279-82. 2009
    ..This study aimed to determine the cellular components of MRI bone oedema, and clarify the relationship between bone erosion and MRI bone oedema...
  57. doi request reprint Mechanisms of bone erosion in gout: a quantitative analysis using plain radiography and computed tomography
    N Dalbeth
    Bone Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Grafton, Auckland, New Zealand
    Ann Rheum Dis 68:1290-5. 2009
    ..The underlying basis of bone erosion in gout remains speculative. The aim of this study was to understand the mechanisms of bone erosion in gout using non-invasive imaging techniques...
  58. ncbi request reprint Tophaceous joint disease strongly predicts hand function in patients with gout
    N Dalbeth
    Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand
    Rheumatology (Oxford) 46:1804-7. 2007
    ..The functional impact of gout is poorly understood. The aim of this study was to determine predictors of hand function in gout...
  59. ncbi request reprint Established rheumatoid arthritis - new imaging modalities
    Fiona M McQueen
    Department of Molecular Medicine and Pathology, University of Auckland, New Zealand
    Best Pract Res Clin Rheumatol 21:841-56. 2007
    ..Bioluminescence and fluorescence reflectance imaging are other approaches that allow imaging, and potentially the delivery of therapeutic agents, at a molecular level...
  60. ncbi request reprint The natural killer cell: a further innate mediator of gouty inflammation?
    Victoria G Empson
    Bone Research Group, Department of Medicine, University of Auckland, Grafton, Auckland, New Zealand
    Immunol Cell Biol 88:24-31. 2010
    ..NK cells also interact with cells of the innate immune system such as monocytes and macrophages. This review outlines the biology of NK cells and the potential role of NK cells in modulating gouty inflammation...
  61. ncbi request reprint Magnetic resonance imaging of the wrist in early rheumatoid arthritis: a pictorial essay
    N R Stewart
    Auckland Radiology Group, 101 Remeura Road, Auckland, New Zealand
    Australas Radiol 45:268-73. 2001
    ..Tenosynovitis can be seen in the wrist in more than half of patients presenting with RA. This most commonly involves the extensor carpi ulnaris tendon and is seen as sheath fluid, thickening and enhancement...
  62. doi request reprint The OMERACT-RAMRIS rheumatoid arthritis magnetic resonance imaging joint space narrowing score: intrareader and interreader reliability and agreement with computed tomography and conventional radiography
    Uffe Møller Døhn
    From the Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Glostrup, Denmark University of Leeds and the UK National Institute for Health Research NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel Maastricht University Medical Center, Maastricht, Netherlands Diakonhjemmet Hospital, Oslo, Norway University of California, San Francisco, CA, USA Slagelse University Hospital, Copenhagen, Denmark Pitié Salpêtriere Hospital, Paris, France University of New South Wales NSW, Sydney, Australia and University of Auckland, Auckland, New Zealand
    J Rheumatol 41:392-7. 2014
    ....
  63. ncbi request reprint Magnetic resonance imaging of the wrist in rheumatoid arthritis: demonstration of progression between 1 and 6 years
    Neal R Stewart
    Department of Radiology, Auckland Hospital, Private Bag 92024, Auckland, New Zealand
    Skeletal Radiol 33:704-11. 2004
    ..To describe the changes seen in the wrist in rheumatoid arthritis (RA) on magnetic resonance (MR) imaging obtained at 1 year and 6 years...
  64. pmc MRI of the wrist in early rheumatoid arthritis can be used to predict functional outcome at 6 years
    N Benton
    Department of Rheumatology, Auckland Hospital, Aukland, New Zealand
    Ann Rheum Dis 63:555-61. 2004
    ..To determine whether magnetic resonance (MR) scans of the dominant wrist of patients with early rheumatoid arthritis (RA) can be used to predict functional outcome at 6 years' follow up...
  65. ncbi request reprint Basing musculoskeletal curriculum changes on the opinions of practicing physicians
    Thomas Pasley
    Medical Education Fellow, Medical Education Division, University of Auckland, Auckland, New Zealand
    N Z Med J 124:27-32. 2011
    ..To establish which musculoskeletal conditions are deemed to be the most important in clinical practice. To use this information to inform the development of a new musculoskeletal curriculum, with emphasis on common and relevant conditions...
  66. pmc A randomised placebo controlled trial of delipidated, deglycolipidated Mycobacterium vaccae as immunotherapy for psoriatic arthritis
    N Dalbeth
    Department of Rheumatology, Auckland Healthcare, Auckland, New Zealand
    Ann Rheum Dis 63:718-22. 2004
    ..To test the hypothesis that PVAC, delipidated, deglycolipidated heat killed Mycobacterium vaccae, is an effective and safe treatment for psoriatic arthritis (PsA). This treatment has shown promising results in psoriasis...
  67. ncbi request reprint The evidence for magnetic resonance imaging as an outcome measure in proof-of-concept rheumatoid arthritis studies
    Philip G Conaghan
    Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, UK
    J Rheumatol 32:2465-9. 2005
    ..We review the extent to which MRI assessments of joint erosion, bone edema, and synovitis fulfil these criteria, particularly as they relate to proof-of-concept RA clinical trials...
  68. ncbi request reprint Dynamic gadolinium-enhanced magnetic resonance imaging of the wrist in patients with rheumatoid arthritis: comment on the article by Cimmino et al
    Fiona M McQueen
    Arthritis Rheum 50:674-5; author reply 675-6. 2004
  69. ncbi request reprint Ultrasonography and magnetic resonance imaging in early rheumatoid arthritis: recent advances
    Mikkel Østergaard
    Departments of Rheumatology, Copenhagen University Hospitals at Hvidovre and Herlev, Kettegaard Alle 30, DK 2650 Hvidovre, Denmark
    Curr Rheumatol Rep 8:378-85. 2006
    ..Data on the value of ultrasonography and MRI are accumulating rapidly, fueling their increasing use in early rheumatoid arthritis. This review focuses on recent advances in the clinical applications of these imaging modalities...
  70. ncbi request reprint Magnetic resonance imaging in rheumatoid arthritis advances and research priorities
    Mikkel Ostergaard
    Copenhagen University Hospitals, Herlev, Copenhagen, Denmark
    J Rheumatol 32:2462-4. 2005
    ....