Susan R McGlashan

Summary

Affiliation: University of Auckland
Country: New Zealand

Publications

  1. ncbi Primary cilia in osteoarthritic chondrocytes: from chondrons to clusters
    S R McGlashan
    Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    Dev Dyn 237:2013-20. 2008
  2. ncbi Development of a method for the measurement of primary cilia length in 3D
    Taryn Saggese
    Department of Anatomy with Radiology, Private Bag 92019, University of Auckland, Auckland 1023, New Zealand
    Cilia 1:11. 2012
  3. ncbi Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes
    Angus K T Wann
    School of Engineering and Materials Science, Queen Mary University of London, London, UK
    FASEB J 26:1663-71. 2012
  4. ncbi Localization of extracellular matrix receptors on the chondrocyte primary cilium
    Susan R McGlashan
    Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
    J Histochem Cytochem 54:1005-14. 2006
  5. ncbi Mechanical loading modulates chondrocyte primary cilia incidence and length
    Susan R McGlashan
    Department of Anatomy with Radiology, University of Auckland, Auckland, New Zealand
    Cell Biol Int 34:441-6. 2010
  6. ncbi Ultrastructural, tomographic and confocal imaging of the chondrocyte primary cilium in situ
    C G Jensen
    Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
    Cell Biol Int 28:101-10. 2004
  7. ncbi Articular cartilage and growth plate defects are associated with chondrocyte cytoskeletal abnormalities in Tg737orpk mice lacking the primary cilia protein polaris
    S R McGlashan
    Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    Matrix Biol 26:234-46. 2007
  8. ncbi The cellular composition and morphological organization of the rostral migratory stream in the adult human brain
    Monica Kam
    Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand
    J Chem Neuroanat 37:196-205. 2009

Collaborators

Detail Information

Publications8

  1. ncbi Primary cilia in osteoarthritic chondrocytes: from chondrons to clusters
    S R McGlashan
    Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    Dev Dyn 237:2013-20. 2008
    ..This is the first study to show that primary cilia are present on chondrocytes throughout OA progression and that the overall percentage of ciliated cells within the degenerating cartilage increases with OA severity...
  2. ncbi Development of a method for the measurement of primary cilia length in 3D
    Taryn Saggese
    Department of Anatomy with Radiology, Private Bag 92019, University of Auckland, Auckland 1023, New Zealand
    Cilia 1:11. 2012
    ..abstract:..
  3. ncbi Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes
    Angus K T Wann
    School of Engineering and Materials Science, Queen Mary University of London, London, UK
    FASEB J 26:1663-71. 2012
    ....
  4. ncbi Localization of extracellular matrix receptors on the chondrocyte primary cilium
    Susan R McGlashan
    Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
    J Histochem Cytochem 54:1005-14. 2006
    ..The data strongly suggest that chondrocyte primary cilia have the necessary machinery to act as mechanosensors, linking the ECM to cytoplasmic organelles responsible for matrix production and secretion...
  5. ncbi Mechanical loading modulates chondrocyte primary cilia incidence and length
    Susan R McGlashan
    Department of Anatomy with Radiology, University of Auckland, Auckland, New Zealand
    Cell Biol Int 34:441-6. 2010
    ..We therefore propose that control of primary cilia length is an adaptive signalling mechanism in response to varying levels and duration of mechanical loads during joint activity...
  6. ncbi Ultrastructural, tomographic and confocal imaging of the chondrocyte primary cilium in situ
    C G Jensen
    Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
    Cell Biol Int 28:101-10. 2004
    ..We conclude that mechanical forces transmitted through these matrix macromolecules bend the primary cilium, identifying it as a potential mechanosensor involved in skeletal patterning and growth...
  7. ncbi Articular cartilage and growth plate defects are associated with chondrocyte cytoskeletal abnormalities in Tg737orpk mice lacking the primary cilia protein polaris
    S R McGlashan
    Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
    Matrix Biol 26:234-46. 2007
    ..These data suggest that failure to form a functional primary cilium affects chondrocyte differentiation and results in delayed chondrocyte hypertrophy within the orpk growth plate...
  8. ncbi The cellular composition and morphological organization of the rostral migratory stream in the adult human brain
    Monica Kam
    Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland, New Zealand
    J Chem Neuroanat 37:196-205. 2009
    ..These findings contribute to the scientific understanding of adult neurogenesis and establish the detailed cytoarchitecture of this novel neurogenic niche in the human brain...