Yan Li

Summary

Affiliation: University of Auckland
Country: New Zealand

Publications

  1. doi Modulatory effects of curcumin on multi-drug resistance-associated protein 5 in pancreatic cancer cells
    Yan Li
    Department of Pharmacology and Clinical Pharmacology, The University of Auckland, Auckland, New Zealand
    Cancer Chemother Pharmacol 68:603-10. 2011
  2. doi Hop-derived prenylflavonoids are substrates and inhibitors of the efflux transporter breast cancer resistance protein (BCRP/ABCG2)
    Kee W Tan
    Food Innovation, The New Zealand Institute for Plant and Food Research Limited, Auckland, New Zealand School of Biological Sciences, Faculty of Science, The University of Auckland, Auckland, New Zealand Department of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
    Mol Nutr Food Res 58:2099-110. 2014
  3. doi Dietary polyacetylenes of the falcarinol type are inhibitors of breast cancer resistance protein (BCRP/ABCG2)
    Kee W Tan
    Food Innovation, The New Zealand Institute for Plant and Food Research Limited, Private Bag 92169, Auckland, New Zealand School of Biological Sciences, Faculty of Science, The University of Auckland, Auckland, New Zealand Department of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand Electronic address
    Eur J Pharmacol 723:346-52. 2014
  4. doi The effects of flavonoids on the ABC transporters: consequences for the pharmacokinetics of substrate drugs
    Yan Li
    Auckland University of Technology, Faculty of Health and Environmental Sciences, Department of Interdisciplinary Studies, Auckland, New Zealand
    Expert Opin Drug Metab Toxicol 9:267-85. 2013
  5. doi Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2)
    Kee W Tan
    Food Innovation, The New Zealand Institute for Plant and Food Research Limited, Private Bag 92169, Auckland, New Zealand
    Food Chem 138:2267-74. 2013
  6. doi Heterocyclic cyclohexanone monocarbonyl analogs of curcumin can inhibit the activity of ATP-binding cassette transporters in cancer multidrug resistance
    Jezrael L Revalde
    Department of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand Electronic address
    Biochem Pharmacol 93:305-17. 2015
  7. doi Interactions of dietary phytochemicals with ABC transporters: possible implications for drug disposition and multidrug resistance in cancer
    Yan Li
    Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
    Drug Metab Rev 42:590-611. 2010
  8. ncbi The role of ABC and SLC transporters in the pharmacokinetics of dietary and herbal phytochemicals and their interactions with xenobiotics
    Yan Li
    Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
    Curr Drug Metab 13:624-39. 2012

Collaborators

  • Kee W Tan
  • Jezrael L Revalde
  • James W Paxton
  • Bill C Hawkins
  • Rhonda J Rosengren

Detail Information

Publications8

  1. doi Modulatory effects of curcumin on multi-drug resistance-associated protein 5 in pancreatic cancer cells
    Yan Li
    Department of Pharmacology and Clinical Pharmacology, The University of Auckland, Auckland, New Zealand
    Cancer Chemother Pharmacol 68:603-10. 2011
    ..Our aim was to evaluate whether curcumin could reverse this multi-drug resistance by inhibition of MRP5-mediated efflux...
  2. doi Hop-derived prenylflavonoids are substrates and inhibitors of the efflux transporter breast cancer resistance protein (BCRP/ABCG2)
    Kee W Tan
    Food Innovation, The New Zealand Institute for Plant and Food Research Limited, Auckland, New Zealand School of Biological Sciences, Faculty of Science, The University of Auckland, Auckland, New Zealand Department of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
    Mol Nutr Food Res 58:2099-110. 2014
    ..This study investigates the interactions between selected prenylflavonoids and breast cancer resistance protein (BCRP/ABCG2), an efflux transporter important for xenobiotic bioavailability and multidrug resistance (MDR)...
  3. doi Dietary polyacetylenes of the falcarinol type are inhibitors of breast cancer resistance protein (BCRP/ABCG2)
    Kee W Tan
    Food Innovation, The New Zealand Institute for Plant and Food Research Limited, Private Bag 92169, Auckland, New Zealand School of Biological Sciences, Faculty of Science, The University of Auckland, Auckland, New Zealand Department of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand Electronic address
    Eur J Pharmacol 723:346-52. 2014
    ....
  4. doi The effects of flavonoids on the ABC transporters: consequences for the pharmacokinetics of substrate drugs
    Yan Li
    Auckland University of Technology, Faculty of Health and Environmental Sciences, Department of Interdisciplinary Studies, Auckland, New Zealand
    Expert Opin Drug Metab Toxicol 9:267-85. 2013
    ....
  5. doi Identification of novel dietary phytochemicals inhibiting the efflux transporter breast cancer resistance protein (BCRP/ABCG2)
    Kee W Tan
    Food Innovation, The New Zealand Institute for Plant and Food Research Limited, Private Bag 92169, Auckland, New Zealand
    Food Chem 138:2267-74. 2013
    ..The identified inhibitory activity of dietary phytochemicals on ABCG2 provides a framework for further investigation of ABCG2-modulated phytochemical bioavailability, MDR, and possible food-drug interactions...
  6. doi Heterocyclic cyclohexanone monocarbonyl analogs of curcumin can inhibit the activity of ATP-binding cassette transporters in cancer multidrug resistance
    Jezrael L Revalde
    Department of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand Electronic address
    Biochem Pharmacol 93:305-17. 2015
    ..From these results, we concluded that MACs, such as the heterocyclic cyclohexanone analogs in this study, also have potential as MDR reversal agents and may be superior alternatives to the unstable parent compound, CUR. ..
  7. doi Interactions of dietary phytochemicals with ABC transporters: possible implications for drug disposition and multidrug resistance in cancer
    Yan Li
    Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
    Drug Metab Rev 42:590-611. 2010
    ..We also discuss the implications that such interactions may have on the pharmacokinetics of xenobiotics and the possible role of phytochemicals in the reversal of multidrug resistance in cancer chemotherapy...
  8. ncbi The role of ABC and SLC transporters in the pharmacokinetics of dietary and herbal phytochemicals and their interactions with xenobiotics
    Yan Li
    Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
    Curr Drug Metab 13:624-39. 2012
    ..This review describes the importance of the ABC and SLC transporters in the pharmacokinetics of dietary and herbal PCs, and their interactions with other xenobiotics...