B Leitch

Summary

Affiliation: University of Otago
Country: New Zealand

Publications

  1. Leitch B, Shevtsova O, Kerr J. Selective reduction in synaptic proteins involved in vesicle docking and signalling at synapses in the ataxic mutant mouse stargazer. J Comp Neurol. 2009;512:52-73 pubmed publisher
    ..These data suggest that the BDNF deficits in the cerebellum of stargazer affect synaptic vesicle docking by selectively altering synaptic-protein distribution and abundance. ..
  2. Leitch B, Shevtsova O, Guevremont D, Williams J. Loss of calcium channels in the cerebellum of the ataxic and epileptic stargazer mutant mouse. Brain Res. 2009;1279:156-67 pubmed publisher
    ..It is therefore possible that stargazin is involved in the trafficking of both AMPARs and VDCCs or in the formation of a functional AMPA receptor-calcium channel complex in the postsynaptic membrane. ..
  3. Leitch B, Szostek A, Lin R, Shevtsova O. Subcellular distribution of L-type calcium channel subtypes in rat hippocampal neurons. Neuroscience. 2009;164:641-57 pubmed publisher
    ..The location of L-type Ca(v)1.2 and Ca(v)1.3 channels in distal dendrites and spines would thus place them at appropriate sites where they could initiate synapse to nucleus signalling. ..