Affiliation: University of Auckland
Country: New Zealand
Vaidyanathan V, Naidu V, Kao C, Karunasinghe N, Bishop K, Wang A, et al
. Environmental factors and risk of aggressive prostate cancer among a population of New Zealand men - a genotypic approach. Mol Biosyst. 2017;13:681-698 pubmed publisher
..The list of genes with SNPs identified as being associated with the risk of PCa in a New Zealand population is provided in the graphical abstract. ..
Bishop K, Erdrich S, Karunasinghe N, Han D, Zhu S, Jesuthasan A, et al
. An investigation into the association between DNA damage and dietary fatty acid in men with prostate cancer. Nutrients. 2015;7:405-22 pubmed publisher
..015). Both the source and type of dietary fat changed significantly over the course of the dietary intervention. Levels of DNA damage were correlated with various dietary fat sources and types of dietary fat. ..
Vaidyanathan V, Krishnamoorthy V, Karunasinghe N, Jabed A, Pallati R, Kao C, et al
. Are We Eating Our Way to Prostate Cancer-A Hypothesis Based on the Evolution, Bioaccumulation, and Interspecific Transfer of miR-150. Noncoding RNA. 2016;2: pubmed publisher
..In this hypothesis-driven review, we have suggested a possible reason as to why miR-150 can be a promising diagnostic biomarker for prostate cancer using theories of evolution, bio-accumulation, and interspecific transfer of miRNAs. ..
Karunasinghe N, Zhu S, Ferguson L. Benefits of Selenium Supplementation on Leukocyte DNA Integrity Interact with Dietary Micronutrients: A Short Communication. Nutrients. 2016;8: pubmed publisher
..The data suggest that Se supplementation is beneficial for the leukocyte DNA integrity only in interaction with the dietary methionine and folate intake. ..
Wang A, ObertovÃ¡ Z, Brown C, Karunasinghe N, Bishop K, Ferguson L, et al
. Risk of fracture in men with prostate cancer on androgen deprivation therapy: a population-based cohort study in New Zealand. BMC Cancer. 2015;15:837 pubmed publisher
..Identification of those at higher risk of fracture and close monitoring of bone health while on ADT is an important factor to consider. This may require monitoring of bone density and bone marker profiles. ..
Karunasinghe N, Zhu Y, Han D, Lange K, Zhu S, Wang A, et al
. Quality of life effects of androgen deprivation therapy in a prostate cancer cohort in New Zealand: can we minimize effects using a stratification based on the aldo-keto reductase family 1, member C3 rs12529 gene polymorphism?. BMC Urol. 2016;16:48 pubmed publisher
..Our data additionally show that with this stratification it could also be possible to identify men needing ADT for better oncological advantage. ..