P E Hughes

Summary

Affiliation: University of Auckland
Country: New Zealand

Publications

  1. ncbi request reprint Activity and injury-dependent expression of inducible transcription factors, growth factors and apoptosis-related genes within the central nervous system
    P E Hughes
    Department of Pharmacology and Clinical Pharmacology and Research Centre for Developmental Medicine and Biology, School of Medicine, The University of Auckland, New Zealand
    Prog Neurobiol 57:421-50. 1999
  2. ncbi request reprint The IGF-I amino-terminal tripeptide glycine-proline-glutamate (GPE) is neuroprotective to striatum in the quinolinic acid lesion animal model of Huntington's disease
    T Alexi
    School of Medicine, University of Auckland, Auckland, New Zealand
    Exp Neurol 159:84-97. 1999
  3. ncbi request reprint Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases
    T Alexi
    Research Centre for Developmental Medicine and Biology, School of Medicine, University of Auckland, New Zealand
    Prog Neurobiol 60:409-70. 2000

Detail Information

Publications3

  1. ncbi request reprint Activity and injury-dependent expression of inducible transcription factors, growth factors and apoptosis-related genes within the central nervous system
    P E Hughes
    Department of Pharmacology and Clinical Pharmacology and Research Centre for Developmental Medicine and Biology, School of Medicine, The University of Auckland, New Zealand
    Prog Neurobiol 57:421-50. 1999
    ..Here we discuss our results which show that pharmacological enhancement of this response with exogenous application of IGF-1 or TGF-beta reduces neuronal loss after brain injury...
  2. ncbi request reprint The IGF-I amino-terminal tripeptide glycine-proline-glutamate (GPE) is neuroprotective to striatum in the quinolinic acid lesion animal model of Huntington's disease
    T Alexi
    School of Medicine, University of Auckland, Auckland, New Zealand
    Exp Neurol 159:84-97. 1999
    ....
  3. ncbi request reprint Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases
    T Alexi
    Research Centre for Developmental Medicine and Biology, School of Medicine, University of Auckland, New Zealand
    Prog Neurobiol 60:409-70. 2000
    ..Most of these approaches hold promise as potential therapies in the treatment of these disorders...