Research Topics
Species | Robert J HancoxSummaryAffiliation: University of Otago Country: New Zealand Publications
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Detail Information
Publications
Association between child and adolescent television viewing and adult health: a longitudinal birth cohort studyRobert J Hancox
Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin New Zealand
Lancet 364:257-62. 2004..However, there have been no longitudinal studies of childhood viewing and adult health. We explored these associations in a birth cohort followed up to age 26 years...
Associations between respiratory symptoms, lung function and gastro-oesophageal reflux symptoms in a population-based birth cohortRobert J Hancox
Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
Respir Res 7:142. 2006..The role of obesity in mediating this association is also unclear. We explored the associations between respiratory symptoms, lung function, and gastro-oesophageal reflux symptoms in a birth cohort of approximately 1000 individuals...
Association between exhaled nitric oxide and systemic inflammatory markersTim J T Sutherland
Dunedin Multidisciplinary Health and Development Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
Ann Allergy Asthma Immunol 99:534-9. 2007..Exhaled nitric oxide is a noninvasive measure of asthmatic airway inflammation...
Leptin, adiponectin, and asthma: findings from a population-based cohort studyTim J T Sutherland
Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
Ann Allergy Asthma Immunol 103:101-7. 2009..Obesity is thought to increase the risk of asthma, especially in women. It has been proposed that this association could be due to the immune-modulating effect of adipokines secreted by adipose tissue...
Association between exhaled nitric oxide and systemic inflammatory markersTim J T Sutherland
Dunedin Multidisciplinary Health and Development Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
Ann Allergy Asthma Immunol 99:334-9. 2007..Exhaled nitric oxide is a noninvasive measure of asthmatic airway inflammation...
Cigarette smoking and allergic sensitization: a 32-year population-based cohort studyRobert J Hancox
Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
J Allergy Clin Immunol 121:38-42.e3. 2008..Cigarette smoke has immunosuppressant effects, but its effect on allergic sensitization is unclear...
Systemic inflammation and lung function in young adultsRobert J Hancox
Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
Thorax 62:1064-8. 2007..We explored the association between the forced expiratory volume in one second (FEV(1)) and the systemic inflammatory marker C-reactive protein (CRP) in young adults...
Accelerated decline in lung function in cigarette smokers is associated with TP53/MDM2 polymorphismsRobert J Hancox
Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
Hum Genet 126:559-65. 2009..These data support the hypothesis that p53 protects from DNA damage in humans and provides a potential explanation for the variation in lung function impairment amongst smokers...
Adolescent screen time and attachment to parents and peersRosalina Richards
Department of Preventive and Social Medicine, Dunedin Medical School, University of Otago, Dunedin, New Zealand 9015
Arch Pediatr Adolesc Med 164:258-62. 2010..To examine associations between screen time (television, video or DVD, gaming, and computer use) and attachment to parents and peers in 2 cohorts of adolescents 16 years apart...
Adiposity, asthma, and airway inflammationChristene R McLachlan
Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
J Allergy Clin Immunol 119:634-9. 2007..One possible explanation might be that these studies have used body mass index to identify adiposity, which might be a less reliable measure of body fat in men than in women...
Relevance of birth cohorts to assessment of asthma persistenceRobert J Hancox
Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, New Zealand
Curr Allergy Asthma Rep 12:175-84. 2012..Understanding the natural history and underlying causes of asthma may lead to development of strategies for primary prevention...
Factors affecting exhaled nitric oxide measurements: the effect of sexD Robin Taylor
Department of Respiratory Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
Respir Res 8:82. 2007..However, many constitutional and environmental factors affect F(E)NO, making it difficult to devise reference values. Our aim was to evaluate the relative importance of factors affecting F(E)NO in a well characterised adult population...
Association between sleep duration and haemoglobin A1c in young adultsRobert J Hancox
Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
J Epidemiol Community Health 66:957-61. 2012..The long-term effects of childhood sleep on glucose metabolism have not been investigated. The authors assessed the associations between childhood and adult sleep duration and adult glycosylated haemoglobin (HbA(1c)) levels...
Programming obesity and poor fitness: the long-term impact of childhood televisionC Erik Landhuis
Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
Obesity (Silver Spring) 16:1457-9. 2008..To assess whether the long-term effects of childhood television viewing on BMI and cardiorespiratory fitness are mediated by adult viewing...
Association of television viewing during childhood with poor educational achievementRobert J Hancox
Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
Arch Pediatr Adolesc Med 159:614-8. 2005..A common concern is that watching too much television may also have a negative impact on education. However, no long-term studies have measured childhood viewing and educational achievement...
Asthma phenotypes: consistency of classification using induced sputumRobert J Hancox
Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, UK
Respirology 17:461-6. 2012..This classification can help determine whether corticosteroid treatment is indicated. We assessed the stability of these phenotypes over time and with different treatment regimens...
Sex differences in the relation between body mass index and asthma and atopy in a birth cohortRobert J Hancox
Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin, New Zealand
Am J Respir Crit Care Med 171:440-5. 2005..It remains unclear if this association is due to genuine asthma or to symptoms caused by overweight, at what age the association develops, and whether it is confined to females...
Cannabis smoking and periodontal disease among young adultsW Murray Thomson
Department of Oral Sciences, Sir John Walsh Research Institute, School of Dentistry, Dunedin, New Zealand
JAMA 299:525-31. 2008..Tobacco smoking is a recognized behavioral risk factor for periodontal disease (through its systemic effects), and cannabis smoking may contribute in a similar way...
C-reactive protein and cardiorespiratory fitness in young adultsMichael J A Williams
Departments of Medical and Surgical Sciences, University of Otago, Dunedin, New Zealand
Eur J Cardiovasc Prev Rehabil 12:216-20. 2005..The aim of this study was to examine the relationship between cardiorespiratory fitness and CRP, controlling for obesity in an unselected cohort of young adults...
Concluding remarks: can we explain the association of beta-agonists with asthma mortality? A hypothesisRobert J Hancox
Department of Preventive and Social Medicine, Dunedin School of Medicine, Dunedin, New Zealand
Clin Rev Allergy Immunol 31:279-88. 2006..Long-acting beta-agonists have also been shown to improve asthma control when taken in combination with inhaled corticosteroids. The clinical significance of tolerance in this context remains to be determined...
Interactions between corticosteroids and beta2-agonistsRobert J Hancox
Department of Preventive and Social Medicine, Dunedin School of Medicine, Dunedin, New Zealand
Clin Rev Allergy Immunol 31:231-46. 2006....
Asthma: time to confront some inconvenient truthsRobert J Hancox
Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
Respirology 15:194-201. 2010..This approach offers the best opportunity to close the gap between what is currently achieved in asthma management and that which is potentially achievable...
Is Salamol less effective than Ventolin? A randomised, blinded, crossover study in New ZealandCatherina L Chang
Department of Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand
N Z Med J 120:U2874. 2007..We compared the efficacy of Salamol and Ventolin inhalers in relieving acute bronchospasm. We also tested the efficacy of partially used Salamol inhalers because of concerns that the device may become blocked during use...
Eosinophils and eosinophilic cationic protein in induced sputum and blood: effects of budesonide and terbutaline treatmentRuth E Aldridge
Canterbury Respiratory Research Unit, Christchurch School of Medicine, University of Otago, Christchurch Hospital, Christchurch, New Zealand
Ann Allergy Asthma Immunol 89:492-7. 2002..We conclude that ECP is not a sensitive or reliable means of evaluating airway inflammation, and can not be recommended for assessing responses to anti-inflammatory therapy...
Overcoming beta-agonist tolerance: high dose salbutamol and ipratropium bromide. Two randomised controlled trialsSarah Haney
Department Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand
Respir Res 8:19. 2007..We assessed the effect of long-acting beta-agonist treatment on the response to 5 mg nebulised salbutamol and to ipratropium bromide...
Female and male antisocial trajectories: from childhood origins to adult outcomesCandice L Odgers
Department of Psychology and Social Behavior, University of California Irvine, Irvine, CA92697 7085, USA
Dev Psychopathol 20:673-716. 2008..Implications for theory, research, and practice are discussed...
Prediction of differential adult health burden by conduct problem subtypes in malesCandice L Odgers
Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, England
Arch Gen Psychiatry 64:476-84. 2007..Whether such developmental subtypes exist in the population and have different prognoses should be rigorously tested to inform the DSM-V...
Tolerance to bronchodilation during treatment with long-acting beta-agonists, a randomised controlled trialSarah Haney
Freeman Hospital, Newcastle upon Tyne, UK
Respir Res 6:107. 2005..This study assessed tolerance to the bronchodilator action of salbutamol during ongoing treatment with long-acting beta-agonist...
Rapid onset of tolerance to beta-agonist bronchodilationSarah Haney
Department of Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand
Respir Med 99:566-71. 2005..CONCLUSIONS: Bronchodilator tolerance occurs after a single dose and reaches a maximum after 1 week of regular formoterol. Sensitivity recovers 3 days after stopping treatment...
Beta2-agonist tolerance and exercise-induced bronchospasmRobert J Hancox
Asthma Research Group, Firestone Institute for Respiratory Health, McMaster University/St Joseph's Hospital, Hamilton, Ontario, Canada
Am J Respir Crit Care Med 165:1068-70. 2002....
Asthma and the elite athlete: summary of the International Olympic Committee's consensus conference, Lausanne, Switzerland, January 22-24, 2008Kenneth D Fitch
School of Sports Science, Exercise and Health, Faculty of Life Sciences, University of Western Australia, Crawley, Australia
J Allergy Clin Immunol 122:254-60, 260.e1-7. 2008..The policy of requiring Olympic athletes to demonstrate the presence of asthma, exercise-induced bronchoconstriction, or AHR to be approved to inhale beta(2)-agonists will continue...
Elevation of cardiac troponins in exacerbation of chronic obstructive pulmonary diseaseMartyn G Harvey
Emergency Department, Monash Medical Centre, Melbourne, Victoria, Australia
Emerg Med Australas 16:212-5. 2004..To investigate the prevalence of serum troponin elevation in patients admitted to hospital with an exacerbation of chronic obstructive pulmonary disease (COPD)...
Recovery from bronchoconstriction and bronchodilator toleranceSarah Haney
Department of Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand
Clin Rev Allergy Immunol 31:181-96. 2006..The extent to which this phenomenon contributes to asthma morbidity and mortality remains to be determined...
