R J Hancox

Summary

Affiliation: University of Otago
Country: New Zealand

Publications

  1. doi request reprint Forceps birth delivery, allergic sensitisation and asthma: a population-based cohort study
    R J Hancox
    Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Clin Exp Allergy 43:332-6. 2013
  2. pmc Childhood and adolescent television viewing and antisocial behavior in early adulthood
    Lindsay A Robertson
    Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Pediatrics 131:439-46. 2013
  3. doi request reprint Association between sleep duration and haemoglobin A1c in young adults
    Robert J Hancox
    Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    J Epidemiol Community Health 66:957-61. 2012
  4. doi request reprint Relevance of birth cohorts to assessment of asthma persistence
    Robert J Hancox
    Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, New Zealand
    Curr Allergy Asthma Rep 12:175-84. 2012
  5. doi request reprint Asthma phenotypes: consistency of classification using induced sputum
    Robert J Hancox
    Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, UK
    Respirology 17:461-6. 2012
  6. pmc Overcoming beta-agonist tolerance: high dose salbutamol and ipratropium bromide. Two randomised controlled trials
    Sarah Haney
    Department Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand
    Respir Res 8:19. 2007
  7. pmc Tolerance to bronchodilation during treatment with long-acting beta-agonists, a randomised controlled trial
    Sarah Haney
    Freeman Hospital, Newcastle upon Tyne, UK
    Respir Res 6:107. 2005
  8. pmc Factors affecting exhaled nitric oxide measurements: the effect of sex
    D Robin Taylor
    Department of Respiratory Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Respir Res 8:82. 2007
  9. ncbi request reprint Watching television is associated with childhood obesity: but is it clinically important?
    R J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, New Zealand
    Int J Obes (Lond) 30:171-5. 2006
  10. ncbi request reprint Association of television viewing during childhood with poor educational achievement
    Robert J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Arch Pediatr Adolesc Med 159:614-8. 2005

Detail Information

Publications51

  1. doi request reprint Forceps birth delivery, allergic sensitisation and asthma: a population-based cohort study
    R J Hancox
    Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Clin Exp Allergy 43:332-6. 2013
    ..It is unknown if other obstetric interventions are associated with allergies...
  2. pmc Childhood and adolescent television viewing and antisocial behavior in early adulthood
    Lindsay A Robertson
    Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Pediatrics 131:439-46. 2013
    ..To investigate whether excessive television viewing throughout childhood and adolescence is associated with increased antisocial behavior in early adulthood...
  3. doi request reprint Association between sleep duration and haemoglobin A1c in young adults
    Robert J Hancox
    Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    J Epidemiol Community Health 66:957-61. 2012
    ..The long-term effects of childhood sleep on glucose metabolism have not been investigated. The authors assessed the associations between childhood and adult sleep duration and adult glycosylated haemoglobin (HbA(1c)) levels...
  4. doi request reprint Relevance of birth cohorts to assessment of asthma persistence
    Robert J Hancox
    Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, New Zealand
    Curr Allergy Asthma Rep 12:175-84. 2012
    ..Understanding the natural history and underlying causes of asthma may lead to development of strategies for primary prevention...
  5. doi request reprint Asthma phenotypes: consistency of classification using induced sputum
    Robert J Hancox
    Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, UK
    Respirology 17:461-6. 2012
    ..This classification can help determine whether corticosteroid treatment is indicated. We assessed the stability of these phenotypes over time and with different treatment regimens...
  6. pmc Overcoming beta-agonist tolerance: high dose salbutamol and ipratropium bromide. Two randomised controlled trials
    Sarah Haney
    Department Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand
    Respir Res 8:19. 2007
    ..We assessed the effect of long-acting beta-agonist treatment on the response to 5 mg nebulised salbutamol and to ipratropium bromide...
  7. pmc Tolerance to bronchodilation during treatment with long-acting beta-agonists, a randomised controlled trial
    Sarah Haney
    Freeman Hospital, Newcastle upon Tyne, UK
    Respir Res 6:107. 2005
    ..This study assessed tolerance to the bronchodilator action of salbutamol during ongoing treatment with long-acting beta-agonist...
  8. pmc Factors affecting exhaled nitric oxide measurements: the effect of sex
    D Robin Taylor
    Department of Respiratory Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Respir Res 8:82. 2007
    ..However, many constitutional and environmental factors affect F(E)NO, making it difficult to devise reference values. Our aim was to evaluate the relative importance of factors affecting F(E)NO in a well characterised adult population...
  9. ncbi request reprint Watching television is associated with childhood obesity: but is it clinically important?
    R J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, New Zealand
    Int J Obes (Lond) 30:171-5. 2006
    ..To assess the impact of television viewing during childhood and adolescence on body mass index (BMI) in children up to the age of 15 years...
  10. ncbi request reprint Association of television viewing during childhood with poor educational achievement
    Robert J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Arch Pediatr Adolesc Med 159:614-8. 2005
    ..A common concern is that watching too much television may also have a negative impact on education. However, no long-term studies have measured childhood viewing and educational achievement...
  11. ncbi request reprint Interactions between corticosteroids and beta2-agonists
    Robert J Hancox
    Department of Preventive and Social Medicine, Dunedin School of Medicine, Dunedin, New Zealand
    Clin Rev Allergy Immunol 31:231-46. 2006
    ....
  12. ncbi request reprint Concluding remarks: can we explain the association of beta-agonists with asthma mortality? A hypothesis
    Robert J Hancox
    Department of Preventive and Social Medicine, Dunedin School of Medicine, Dunedin, New Zealand
    Clin Rev Allergy Immunol 31:279-88. 2006
    ..Long-acting beta-agonists have also been shown to improve asthma control when taken in combination with inhaled corticosteroids. The clinical significance of tolerance in this context remains to be determined...
  13. pmc Associations between respiratory symptoms, lung function and gastro-oesophageal reflux symptoms in a population-based birth cohort
    Robert J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Respir Res 7:142. 2006
    ..The role of obesity in mediating this association is also unclear. We explored the associations between respiratory symptoms, lung function, and gastro-oesophageal reflux symptoms in a birth cohort of approximately 1000 individuals...
  14. pmc Systemic inflammation and lung function in young adults
    Robert J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Thorax 62:1064-8. 2007
    ..We explored the association between the forced expiratory volume in one second (FEV(1)) and the systemic inflammatory marker C-reactive protein (CRP) in young adults...
  15. ncbi request reprint Cigarette smoking and allergic sensitization: a 32-year population-based cohort study
    Robert J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    J Allergy Clin Immunol 121:38-42.e3. 2008
    ..Cigarette smoke has immunosuppressant effects, but its effect on allergic sensitization is unclear...
  16. doi request reprint Associations between birth weight, early childhood weight gain and adult lung function
    R J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Thorax 64:228-32. 2009
    ..It is also unclear whether postnatal growth affects adult lung function. The associations between birth weight, postnatal growth and adult lung function were assessed in an unselected birth cohort of 1037 children...
  17. pmc Correlation between measures of insulin resistance in fasting and non-fasting blood
    Robert J Hancox
    Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Diabetol Metab Syndr 3:23. 2011
    ..abstract:..
  18. ncbi request reprint Sex differences in the relation between body mass index and asthma and atopy in a birth cohort
    Robert J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin, New Zealand
    Am J Respir Crit Care Med 171:440-5. 2005
    ..It remains unclear if this association is due to genuine asthma or to symptoms caused by overweight, at what age the association develops, and whether it is confined to females...
  19. pmc Effects of cannabis on lung function: a population-based cohort study
    R J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Eur Respir J 35:42-7. 2010
    ..Cannabis use was associated with higher lung volumes, suggesting hyperinflation and increased large-airways resistance, but there was little evidence for airflow obstruction or impairment of gas transfer...
  20. ncbi request reprint Effects of terbutaline and budesonide on sputum cells and bronchial hyperresponsiveness in asthma
    R E Aldridge
    Canterbury and Otago Respiratory Research Groups, Christchurch and Dunedin Schools of Medicine, University of Otago, Christchurch, New Zealand
    Am J Respir Crit Care Med 161:1459-64. 2000
    ..These findings support the hypothesis that short-acting beta-agonists have a permissive effect on airway inflammation and that when used in high dose there may be an unfavorable interaction with inhaled corticosteroids...
  21. pmc Relationship between socioeconomic status and asthma: a longitudinal cohort study
    R J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Thorax 59:376-80. 2004
    ..Most of these studies have been cross sectional in design and have relied on subjective markers of asthma such as symptoms of wheeze. Many have been unable to control adequately for potential confounding factors...
  22. ncbi request reprint Reversing acute bronchoconstriction in asthma: the effect of bronchodilator tolerance after treatment with formoterol
    S L Jones
    Dept of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, New Zealand
    Eur Respir J 17:368-73. 2001
    ..This bronchodilator tolerance is evident in circumstances of acute bronchconstriction...
  23. ncbi request reprint Association between C-reactive protein, metabolic cardiovascular risk factors, obesity and oral contraceptive use in young adults
    M J A Williams
    Department of Medical and Surgical Sciences, University of Otago, Dunedin, New Zealand
    Int J Obes Relat Metab Disord 28:998-1003. 2004
    ..This study sought to determine the relationship between levels of the inflammatory marker, C-reactive protein (CRP), cardiovascular risk factors and oral contraceptive use in young adults...
  24. ncbi request reprint Bronchodilator tolerance: the impact of increasing bronchoconstriction
    J M Wraight
    Dept of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Eur Respir J 21:810-5. 2003
    ..Increasing bronchoconstriction conferred greater susceptibility to the effects of bronchodilator tolerance...
  25. doi request reprint Leptin, adiponectin, and asthma: findings from a population-based cohort study
    Tim J T Sutherland
    Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Ann Allergy Asthma Immunol 103:101-7. 2009
    ..Obesity is thought to increase the risk of asthma, especially in women. It has been proposed that this association could be due to the immune-modulating effect of adipokines secreted by adipose tissue...
  26. ncbi request reprint Exhaled NO and assessment of anti-inflammatory effects of inhaled steroid: dose-response relationship
    S L Jones
    Dept of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, New Zealand
    Eur Respir J 20:601-8. 2002
    ..The relationship found in this study was linear over the dose range 0-500 microg x day(-1) soon after commencing therapy and continued over time...
  27. pmc Asthma exacerbations during long term beta agonist use: influence of beta(2) adrenoceptor polymorphism
    D R Taylor
    Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Thorax 55:762-7. 2000
    ..Polymorphisms of the beta(2) adrenoceptor influence receptor function in vitro and asthma phenotypes in vivo. However, their importance in determining responses to inhaled beta agonist treatment has not been clearly defined...
  28. ncbi request reprint The influence of polymorphism at position 16 of the beta2-adrenoceptor on the development of tolerance to beta-agonist
    D R Taylor
    Dunedin School of Medicine, University of Otago, New Zealand
    J Asthma 37:691-700. 2000
    ..Thus, although tolerance is influenced in vitro by polymorphism of the beta2-adrenoceptor, the magnitude of between-genotype differences in vivo is unlikely to be significant...
  29. ncbi request reprint Long-acting beta-agonist treatment in patients with persistent asthma already receiving inhaled corticosteroids
    R J Hancox
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    BioDrugs 15:11-24. 2001
    ..Guidelines for the management of patients with chronic persistent asthma are likely to require modification to reflect these developments...
  30. ncbi request reprint The predictive value of exhaled nitric oxide measurements in assessing changes in asthma control
    S L Jones
    Department of Medical and Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Am J Respir Crit Care Med 164:738-43. 2001
    ..We conclude that eNO measurements are as useful as induced sputum analysis and AHR in assessing airway inflammation, with the advantage that they are easy to perform...
  31. ncbi request reprint Association between exhaled nitric oxide and systemic inflammatory markers
    Tim J T Sutherland
    Dunedin Multidisciplinary Health and Development Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Ann Allergy Asthma Immunol 99:334-9. 2007
    ..Exhaled nitric oxide is a noninvasive measure of asthmatic airway inflammation...
  32. ncbi request reprint Psychosocial correlates of 6-n-propylthiouracil (PROP) ratings in a birth cohort
    H M McAnally
    Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, University of Otago, P O Box 913, Dunedin, New Zealand
    Appetite 49:700-3. 2007
    ..12). Results suggest that psychosocial variables, sex and scale use, in addition to established genetic determinants, may help explain variability in ratings of supra-threshold concentrations of PROP...
  33. pmc Changes in medication use from age 26 to 32 in a representative birth cohort
    W M Thomson
    Department of Oral Sciences, Faculty of Dentistry, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Intern Med J 37:543-9. 2007
    ..The aim of the study was to examine changes in medication usage between ages 26 and 32 in a prospective study of a representative birth cohort...
  34. ncbi request reprint Association between child and adolescent television viewing and adult health: a longitudinal birth cohort study
    Robert J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin New Zealand
    Lancet 364:257-62. 2004
    ..However, there have been no longitudinal studies of childhood viewing and adult health. We explored these associations in a birth cohort followed up to age 26 years...
  35. ncbi request reprint Adiposity, asthma, and airway inflammation
    Christene R McLachlan
    Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    J Allergy Clin Immunol 119:634-9. 2007
    ..One possible explanation might be that these studies have used body mass index to identify adiposity, which might be a less reliable measure of body fat in men than in women...
  36. ncbi request reprint C-reactive protein and cardiorespiratory fitness in young adults
    Michael J A Williams
    Departments of Medical and Surgical Sciences, University of Otago, Dunedin, New Zealand
    Eur J Cardiovasc Prev Rehabil 12:216-20. 2005
    ..The aim of this study was to examine the relationship between cardiorespiratory fitness and CRP, controlling for obesity in an unselected cohort of young adults...
  37. pmc Cannabis smoking and periodontal disease among young adults
    W Murray Thomson
    Department of Oral Sciences, Sir John Walsh Research Institute, School of Dentistry, Dunedin, New Zealand
    JAMA 299:525-31. 2008
    ..Tobacco smoking is a recognized behavioral risk factor for periodontal disease (through its systemic effects), and cannabis smoking may contribute in a similar way...
  38. ncbi request reprint Association between exhaled nitric oxide and systemic inflammatory markers
    Tim J T Sutherland
    Dunedin Multidisciplinary Health and Development Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Ann Allergy Asthma Immunol 99:534-9. 2007
    ..Exhaled nitric oxide is a noninvasive measure of asthmatic airway inflammation...
  39. doi request reprint Adolescent screen time and attachment to parents and peers
    Rosalina Richards
    Department of Preventive and Social Medicine, Dunedin Medical School, University of Otago, Dunedin, New Zealand 9015
    Arch Pediatr Adolesc Med 164:258-62. 2010
    ..To examine associations between screen time (television, video or DVD, gaming, and computer use) and attachment to parents and peers in 2 cohorts of adolescents 16 years apart...
  40. doi request reprint Programming obesity and poor fitness: the long-term impact of childhood television
    C Erik Landhuis
    Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Obesity (Silver Spring) 16:1457-9. 2008
    ..To assess whether the long-term effects of childhood television viewing on BMI and cardiorespiratory fitness are mediated by adult viewing...
  41. ncbi request reprint Eosinophils and eosinophilic cationic protein in induced sputum and blood: effects of budesonide and terbutaline treatment
    Ruth E Aldridge
    Canterbury Respiratory Research Unit, Christchurch School of Medicine, University of Otago, Christchurch Hospital, Christchurch, New Zealand
    Ann Allergy Asthma Immunol 89:492-7. 2002
    ..Eosinophilic cationic protein (ECP) levels in sputum and blood correlate with clinical severity, and serial measurements of ECP have been proposed as a suitable candidate...
  42. pmc Accelerated decline in lung function in cigarette smokers is associated with TP53/MDM2 polymorphisms
    Robert J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Hum Genet 126:559-65. 2009
    ..These data support the hypothesis that p53 protects from DNA damage in humans and provides a potential explanation for the variation in lung function impairment amongst smokers...
  43. doi request reprint Asthma: time to confront some inconvenient truths
    Robert J Hancox
    Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
    Respirology 15:194-201. 2010
    ..This approach offers the best opportunity to close the gap between what is currently achieved in asthma management and that which is potentially achievable...
  44. doi request reprint Female and male antisocial trajectories: from childhood origins to adult outcomes
    Candice L Odgers
    Department of Psychology and Social Behavior, University of California Irvine, Irvine, CA92697 7085, USA
    Dev Psychopathol 20:673-716. 2008
    ..Implications for theory, research, and practice are discussed...
  45. ncbi request reprint Is Salamol less effective than Ventolin? A randomised, blinded, crossover study in New Zealand
    Catherina L Chang
    Department of Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand
    N Z Med J 120:U2874. 2007
    ..We compared the efficacy of Salamol and Ventolin inhalers in relieving acute bronchospasm. We also tested the efficacy of partially used Salamol inhalers because of concerns that the device may become blocked during use...
  46. ncbi request reprint Beta2-agonist tolerance and exercise-induced bronchospasm
    Robert J Hancox
    Asthma Research Group, Firestone Institute for Respiratory Health, McMaster University St Joseph s Hospital, Hamilton, Ontario, Canada
    Am J Respir Crit Care Med 165:1068-70. 2002
    ....
  47. ncbi request reprint Prediction of differential adult health burden by conduct problem subtypes in males
    Candice L Odgers
    Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, England
    Arch Gen Psychiatry 64:476-84. 2007
    ..Whether such developmental subtypes exist in the population and have different prognoses should be rigorously tested to inform the DSM-V...
  48. ncbi request reprint Rapid onset of tolerance to beta-agonist bronchodilation
    Sarah Haney
    Department of Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand
    Respir Med 99:566-71. 2005
    ..This is easily demonstrated if dilation is tested following methacholine challenge. It is not known how quickly tolerance develops or how long it lasts after stopping beta-agonist therapy...
  49. ncbi request reprint Recovery from bronchoconstriction and bronchodilator tolerance
    Sarah Haney
    Department of Respiratory Medicine, Waikato Hospital, Hamilton, New Zealand
    Clin Rev Allergy Immunol 31:181-96. 2006
    ..The extent to which this phenomenon contributes to asthma morbidity and mortality remains to be determined...
  50. ncbi request reprint Elevation of cardiac troponins in exacerbation of chronic obstructive pulmonary disease
    Martyn G Harvey
    Emergency Department, Monash Medical Centre, Melbourne, Victoria, Australia
    Emerg Med Australas 16:212-5. 2004
    ..To investigate the prevalence of serum troponin elevation in patients admitted to hospital with an exacerbation of chronic obstructive pulmonary disease (COPD)...
  51. doi request reprint Asthma and the elite athlete: summary of the International Olympic Committee's consensus conference, Lausanne, Switzerland, January 22-24, 2008
    Kenneth D Fitch
    School of Sports Science, Exercise and Health, Faculty of Life Sciences, University of Western Australia, Crawley, Australia
    J Allergy Clin Immunol 122:254-60, 260.e1-7. 2008
    ..The policy of requiring Olympic athletes to demonstrate the presence of asthma, exercise-induced bronchoconstriction, or AHR to be approved to inhale beta(2)-agonists will continue...