S P Gieseg

Summary

Affiliation: University of Canterbury
Country: New Zealand

Publications

  1. pmc Potential to inhibit growth of atherosclerotic plaque development through modulation of macrophage neopterin/7,8-dihydroneopterin synthesis
    S P Gieseg
    School of Biological Sciences, University of Canterbury, Christchurch, New Zealand
    Br J Pharmacol 153:627-35. 2008
  2. ncbi Macrophage antioxidant protection within atherosclerotic plaques
    Steven P Gieseg
    Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
    Front Biosci (Landmark Ed) 14:1230-46. 2009
  3. doi Oxidant production, oxLDL uptake, and CD36 levels in human monocyte–derived macrophages are downregulated by the macrophage-generated antioxidant 7,8-dihydroneopterin
    Steven P Gieseg
    Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Christchurch, New Zealand
    Antioxid Redox Signal 13:1525-34. 2010
  4. ncbi Protection of erythrocytes by the macrophage synthesized antioxidant 7,8 dihydroneopterin
    S P Gieseg
    Free Radical Biochemistry Laboratory, Department of Zoology, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
    Free Radic Res 34:123-36. 2001
  5. ncbi A comparison of plasma vitamin C and E levels in two Antarctic and two temperate water fish species
    S P Gieseg
    Department of Zoology, University of Canterbury, Christchurch, New Zealand
    Comp Biochem Physiol B Biochem Mol Biol 125:371-8. 2000
  6. ncbi Protection of U937 cells from free radical damage by the macrophage synthesized antioxidant 7,8-dihydroneopterin
    S P Gieseg
    Free Radical Biochemistry Laboratory, Department of Zoology, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
    Free Radic Res 35:311-8. 2001
  7. doi Spectral CT of carotid atherosclerotic plaque: comparison with histology
    R Zainon
    Department of Physics and Astronomy, University of Canterbury, Christchurch, New Zealand
    Eur Radiol 22:2581-8. 2012

Collaborators

  • N G Anderson
  • R Zainon
  • T Janmale
  • R M Doesburg
  • P H Butler
  • T M Buckenham
  • J A Roake
  • J P Ronaldson
  • A P H Butler
  • N J Scott

Detail Information

Publications7

  1. pmc Potential to inhibit growth of atherosclerotic plaque development through modulation of macrophage neopterin/7,8-dihydroneopterin synthesis
    S P Gieseg
    School of Biological Sciences, University of Canterbury, Christchurch, New Zealand
    Br J Pharmacol 153:627-35. 2008
    ..How these activities might influence or modulate the development of atherosclerotic plaque in vivo will be explored in this review...
  2. ncbi Macrophage antioxidant protection within atherosclerotic plaques
    Steven P Gieseg
    Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
    Front Biosci (Landmark Ed) 14:1230-46. 2009
    ..The evidence that these antioxidants provide further protection, so allowing the macrophage cells to survive within sites of chronic inflammation such as atherosclerotic plaques, will be described...
  3. doi Oxidant production, oxLDL uptake, and CD36 levels in human monocyte–derived macrophages are downregulated by the macrophage-generated antioxidant 7,8-dihydroneopterin
    Steven P Gieseg
    Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Christchurch, New Zealand
    Antioxid Redox Signal 13:1525-34. 2010
    ..These results imply that 7,8-dihydroneopterin protects human macrophages both by scavenging oxidants generated in response to oxLDL and by decreasing CD36-mediated uptake of oxLDL...
  4. ncbi Protection of erythrocytes by the macrophage synthesized antioxidant 7,8 dihydroneopterin
    S P Gieseg
    Free Radical Biochemistry Laboratory, Department of Zoology, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
    Free Radic Res 34:123-36. 2001
    ..The cellular antioxidant properties of 78NP suggest it may have a role in protecting immune cells from free radical damage during inflammation...
  5. ncbi A comparison of plasma vitamin C and E levels in two Antarctic and two temperate water fish species
    S P Gieseg
    Department of Zoology, University of Canterbury, Christchurch, New Zealand
    Comp Biochem Physiol B Biochem Mol Biol 125:371-8. 2000
    ..The data suggest that even though Antarctic fish live at -1.5 degrees C they may be exposed to greater metabolic stress from free radical mediated oxidation than temperate water species...
  6. ncbi Protection of U937 cells from free radical damage by the macrophage synthesized antioxidant 7,8-dihydroneopterin
    S P Gieseg
    Free Radical Biochemistry Laboratory, Department of Zoology, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
    Free Radic Res 35:311-8. 2001
    ..Our data suggests macrophages may synthesize 7,8-NP for antioxidant protection during inflammatory events in vivo...
  7. doi Spectral CT of carotid atherosclerotic plaque: comparison with histology
    R Zainon
    Department of Physics and Astronomy, University of Canterbury, Christchurch, New Zealand
    Eur Radiol 22:2581-8. 2012
    ..To distinguish components of vulnerable atherosclerotic plaque by imaging their energy response using spectral CT and comparing images with histology...