Research Topics
| E GaneSummaryAffiliation: University of Auckland Country: New Zealand Publications
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Detail Information
Publications
Management of chronic viral hepatitis before and after renal transplantationEdward Gane
New Zealand Liver Transplant Unit, Auckland Hospital, New Zealand
Transplantation 74:427-37. 2002..Established cirrhosis with active viral infection should be considered a relative contraindication to isolated renal transplantation...
A randomized study of adefovir dipivoxil in place of HBIG in combination with lamivudine as post-liver transplantation hepatitis B prophylaxisPeter W Angus
Victorian Liver Transplant Unit, Austin Health, Victoria, Australia
Hepatology 48:1460-6. 2008..CONCLUSION: Compared with combination HBIG plus lamivudine prophylaxis, combination adefovir plus lamivudine provides equivalent protection against recurrent HBV infection but with better tolerability and less cost...
Liver transplantation in New Zealand: the first four yearsEd Gane
New Zealand Liver Transplant Unit, Auckland Hospital, Auckland, New Zealand
N Z Med J 115:U120. 2002..To summarise the transplant-related activity of the New Zealand Liver Transplant Unit over the first four years...
Treatment of recurrent hepatitis CEd Gane
New Zealand Liver Transplant Unit, Auckland Hospital, Auckland, NZ
Liver Transpl 8:S28-37. 2002..9. In a recent study, posttransplant immunoprophylaxis with polyclonal hepatitis C immunoglobulin had no effect on recurrent viremia or hepatitis...
The natural history and outcome of liver transplantation in hepatitis C virus-infected recipientsEdward Gane
New Zealand Liver Transplant Unit, Auckland Hospital, Auckland, New Zealand
Liver Transpl 9:S28-34. 2003..The 3-year survival is <10% after the onset of hepatitis C virus-related allograft failure, compared with 60% after decompensation in immunocompetent patients...
Treatment of chronic hepatitis C in patients with renal diseaseEdward Gane
New Zealand Liver Transplant Unit, Auckland Hospital, Auckland, New Zealand
Med J Malaysia 60:72-6. 2005
Liver transplantation in chronic hepatitis BEdward Gane
New Zealand Liver Transplant Unit, Auckland Hospital, Auckland, New Zealand
Med J Malaysia 60:88-9. 2005
Viral and metabolic factors influencing alanine aminotransferase activity in patients with chronic hepatitis CDaniele Prati
Ospedale A Manzoni, Lecco and IRCCS Ospedale Maggiore Policlinico Mangiagalli e Regina Elena, Milan, Italy
J Hepatol 44:679-85. 2006..To clarify the role and interactions of viral and host factors in inducing liver cell injury, we examined the associations of several virological and metabolic variables with serum alanine aminotransferase levels...
Treatment of chronic hepatitis C patients with persistently normal alanine aminotransferase levels with the combination of peginterferon alpha-2a (40 kDa) plus ribavirin: impact on health-related quality of lifeSanjeev Arora
Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131 0001, USA
J Gastroenterol Hepatol 21:406-12. 2006..HRQoL in the present population was also compared with HRQoL in patients with elevated ALT levels, observed in a previous study...
Therapeutic vaccination of chronic hepatitis B patients with virus suppression by antiviral therapy: a randomized, controlled study of co-administration of HBsAg/AS02 candidate vaccine and lamivudinePierre Vandepapeliere
GlaxoSmithKline Biologicals, 1330 Rixensart, Belgium
Vaccine 25:8585-97. 2007....
Telbivudine versus lamivudine in patients with chronic hepatitis BChing Lung Lai
University Department of Medicine, Queen Mary Hospital, Hong Kong, China
N Engl J Med 357:2576-88. 2007..Reducing hepatitis B virus (HBV) replication to minimal levels is emerging as a key therapeutic goal for chronic hepatitis B...
Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis BGeorge K K Lau
Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong SAR, China
N Engl J Med 352:2682-95. 2005....
Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2005 updateYun Fan Liaw
Liver Research Unit, Chang Gung Memorial Hospital, Taipei, Taiwan
Liver Int 25:472-89. 2005..A large amount of new data on the treatment of chronic hepatitis B has become available such that the 2003 consensus statement requires revision and update...
Screening for chronic hepatitis B infection in New Zealand: unfinished businessEdward Gane
N Z Med J 118:U1344. 2005
Peginterferon alfa-2a (40 kilodaltons) and ribavirin in patients with chronic hepatitis C and normal aminotransferase levelsStefan Zeuzem
Saarland University Hospital, Homburg Saar, Germany
Gastroenterology 127:1724-32. 2004....
Peginterferon alpha-2a (40kD) [Pegasys] improves HR-QOL outcomes compared with unmodified interferon alpha-2a [Roferon-A]: in patients with chronic hepatitis CJens Rasenack
Klinikum der Albert Ludwigs Universität, Freiburg, Germany
Pharmacoeconomics 21:341-9. 2003..Treatment with peginterferon alpha-2a (40kD) provides an improved sustained response over unmodified interferon alpha-2a...
Sorafenib in advanced hepatocellular carcinomaJosep M Llovet
Barcelona Clinic Liver Cancer Group, Institut d Investigacions Biomediques August Pi i Sunyer, Centro de Investigaciones en Red de Enfermedades Hepáticas y Digestivas Hospital Clínic Barcelona, Barcelona
N Engl J Med 359:378-90. 2008..A preliminary study suggested that sorafenib, an oral multikinase inhibitor of the vascular endothelial growth factor receptor, the platelet-derived growth factor receptor, and Raf may be effective in hepatocellular carcinoma...
Patient and graft survival after liver transplantation for hereditary hemochromatosis: Implications for pathogenesisDarrell H G Crawford
Queensland Liver Transplant Service and The University of Queensland, Princess Alexandra Hospital, Brisbane, Australia
Hepatology 39:1655-62. 2004..Our data suggest that iron excess in HH does not wholly depend on intestinal iron absorption but is also influenced by liver factors that moderate iron metabolism...
Liver transplantation in Jehovah's Witness patients in AustralasiaGary P Jeffrey
Western Australian Liver Transplantation Service, Sir Charles Gairdner Hospital, Perth, WA, Australia
Med J Aust 187:188-9. 2007..To our knowledge, these are the first such cases in Australasia. The techniques used to minimise blood loss and transfusion requirements could potentially benefit all patients undergoing major surgery...
Polymorphism in intron 1 of the interferon-gamma gene influences both serum immunoglobulin E levels and the risk for chronic hepatitis B virus infection in PolynesiansWilliam Abbott
New Zealand Liver Transplant Unit, Auckland City Hospital, Private Bag 92 024, Auckland, New Zealand
Immunogenetics 59:187-95. 2007..These findings are consistent with a previous report of an association between +875 IFNGCA and [tsIgE] and provide preliminary evidence of a new association with the outcome of an HBV infection...
Practical difficulties in the management of hepatitis B in the Asia-Pacific regionRosmawati Mohamed
Department of Medicine, University Malaya, Kuala Lumpur, Malaysia
J Gastroenterol Hepatol 19:958-69. 2004....
Resolution of alcoholic neuropathy following liver transplantationEdward Gane
New Zealand Liver Transplant Unit, Auckland City Hospital, Auckland, New Zealand
Liver Transpl 10:1545-8. 2004..In conclusion, this case suggests that peripheral neuropathy in a patient with alcoholic cirrhosis may resolve following liver transplantation and should not constitute a contraindication to transplantation, even when it is disabling...
Liver transplantation for hepatocellular carcinoma in New Zealand: a prospective intent-to-treat analysisYuhji Marui
New Zealand Liver Transplant Unit, Auckland City Hospital, Auckland, New Zealand
N Z Med J 118:U1532. 2005..Based on this experience strategies aimed at preventing waiting list drop out have been adopted, however expansion of tumour-related selection criteria cannot be recommended without a concomitant increase in donor organ availability...
