John D Fraser

Summary

Affiliation: University of Auckland
Country: New Zealand

Publications

  1. pmc Antigen targeting to major histocompatibility complex class II with streptococcal mitogenic exotoxin Z-2 M1, a superantigen-based vaccine carrier
    Fiona J Radcliff
    School of Medical Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand
    Clin Vaccine Immunol 19:574-86. 2012
  2. pmc The streptococcal superantigen SMEZ exhibits wide allelic variation, mosaic structure, and significant antigenic variation
    T Proft
    Department of Molecular Medicine, School of Medicine, University of Auckland, Auckland, New Zealand
    J Exp Med 191:1765-76. 2000

Collaborators

  • Fiona J Radcliff
  • Diana Schuhbauer
  • Jacelyn M S Loh
  • Birgit Ha
  • James McCluskey
  • T Proft
  • A Paterson
  • K D Weller
  • D Martin
  • S L Moffatt

Detail Information

Publications2

  1. pmc Antigen targeting to major histocompatibility complex class II with streptococcal mitogenic exotoxin Z-2 M1, a superantigen-based vaccine carrier
    Fiona J Radcliff
    School of Medical Sciences and Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand
    Clin Vaccine Immunol 19:574-86. 2012
    ..Coupling of a TCR-defective superantigen toxoid presents a new strategy for conjugate vaccines with the additional benefit of targeted delivery to MHC class II-bearing cells...
  2. pmc The streptococcal superantigen SMEZ exhibits wide allelic variation, mosaic structure, and significant antigenic variation
    T Proft
    Department of Molecular Medicine, School of Medicine, University of Auckland, Auckland, New Zealand
    J Exp Med 191:1765-76. 2000
    ..SMEZ-specific Vbeta8 activity was found in culture supernatants of 66% of the GAS isolates, indicating a potential base for the development of a SMEZ targeting vaccine...