Michael T Cooling

Summary

Affiliation: University of Auckland
Country: New Zealand

Publications

  1. ncbi request reprint Distributed model construction with virtual parts
    Michael T Cooling
    Auckland Bioengineering Institute, University of Auckland, UniServices House, Room 639, 70 Symonds Street, Auckland, New Zealand
    Methods Mol Biol 1244:301-22. 2015
  2. pmc Revision history aware repositories of computational models of biological systems
    Andrew K Miller
    Auckland Bioengineering Institute, The University of Auckland, Private Bag 92019, Auckland, NZ
    BMC Bioinformatics 12:22. 2011
  3. pmc Modeling hypertrophic IP3 transients in the cardiac myocyte
    Michael Cooling
    Auckland Bioengineering Institute, Department of Engineering Science, University of Auckland, New Zealand
    Biophys J 93:3421-33. 2007
  4. ncbi request reprint Modelling biological modularity with CellML
    M T Cooling
    Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand
    IET Syst Biol 2:73-9. 2008
  5. pmc Sensitivity of NFAT cycling to cytosolic calcium concentration: implications for hypertrophic signals in cardiac myocytes
    Michael T Cooling
    Auckland Bioengineering Institute, The University of Auckland, New Zealand
    Biophys J 96:2095-104. 2009
  6. ncbi request reprint Standard virtual biological parts: a repository of modular modeling components for synthetic biology
    M T Cooling
    Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand
    Bioinformatics 26:925-31. 2010
  7. ncbi request reprint Multiscale modeling of intracranial aneurysms: cell signaling, hemodynamics, and remodeling
    Harvey Ho
    Auckland Bioengineering Institute, The University of Auckland, Auckland 1142, New Zealand
    IEEE Trans Biomed Eng 58:2974-7. 2011
  8. ncbi request reprint The Physiome Model Repository 2
    Tommy Yu
    Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand
    Bioinformatics 27:743-4. 2011

Detail Information

Publications8

  1. ncbi request reprint Distributed model construction with virtual parts
    Michael T Cooling
    Auckland Bioengineering Institute, University of Auckland, UniServices House, Room 639, 70 Symonds Street, Auckland, New Zealand
    Methods Mol Biol 1244:301-22. 2015
    ..The models are stored in an online system (the Physiome Model Repository) with distributed source and access control, demonstrating a collaborative method for creating mathematical models from reusable components. ..
  2. pmc Revision history aware repositories of computational models of biological systems
    Andrew K Miller
    Auckland Bioengineering Institute, The University of Auckland, Private Bag 92019, Auckland, NZ
    BMC Bioinformatics 12:22. 2011
    ..However, to date, there has been no published research on how DVCSs can be applied to repositories of computational models of biological systems...
  3. pmc Modeling hypertrophic IP3 transients in the cardiac myocyte
    Michael Cooling
    Auckland Bioengineering Institute, Department of Engineering Science, University of Auckland, New Zealand
    Biophys J 93:3421-33. 2007
    ....
  4. ncbi request reprint Modelling biological modularity with CellML
    M T Cooling
    Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand
    IET Syst Biol 2:73-9. 2008
    ..Finally, the authors discuss the dilemmas associated with modelling protein-to-protein interactions, and the vision for using future CellML enhancements to resolve potential duplications when combining independently developed models...
  5. pmc Sensitivity of NFAT cycling to cytosolic calcium concentration: implications for hypertrophic signals in cardiac myocytes
    Michael T Cooling
    Auckland Bioengineering Institute, The University of Auckland, New Zealand
    Biophys J 96:2095-104. 2009
    ..We find that NFAT cycling is sensitive to excitation-transcription coupling even when both calcium signals are in the same cellular compartment, thus showing that separation of the signals may not be necessary in vitro...
  6. ncbi request reprint Standard virtual biological parts: a repository of modular modeling components for synthetic biology
    M T Cooling
    Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand
    Bioinformatics 26:925-31. 2010
    ..To this end, the ongoing standardization of biological parts presents an opportunity to develop libraries of standard virtual parts in the form of mathematical models that can be combined to inform system design...
  7. ncbi request reprint Multiscale modeling of intracranial aneurysms: cell signaling, hemodynamics, and remodeling
    Harvey Ho
    Auckland Bioengineering Institute, The University of Auckland, Auckland 1142, New Zealand
    IEEE Trans Biomed Eng 58:2974-7. 2011
    ..A computational framework for combining them is presented. We conclude with a discussion of the advantages and challenges of the approach...
  8. ncbi request reprint The Physiome Model Repository 2
    Tommy Yu
    Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand
    Bioinformatics 27:743-4. 2011
    ..Key advantages brought to the end user by PMR2 include: facilities for model exchange, enhanced collaboration and a detailed change history for each model...