Sharon R Browning

Summary

Affiliation: University of Auckland
Country: New Zealand

Publications

  1. pmc Multilocus analysis of GAW15 NARAC chromosome 18 case-control data
    Sharon R Browning
    Department of Statistics, The University of Auckland, Private Bag 92019, Auckland, New Zealand
    BMC Proc 1:S11. 2007
  2. pmc Multilocus association mapping using variable-length Markov chains
    Sharon R Browning
    Department of Statistics, The University of Auckland, Auckland 92019, New Zealand
    Am J Hum Genet 78:903-13. 2006
  3. pmc Haplotypic analysis of Wellcome Trust Case Control Consortium data
    Brian L Browning
    Department of Statistics, The University of Auckland, Private Bag 92019, Auckland, New Zealand
    Hum Genet 123:273-80. 2008
  4. pmc Missing data imputation and haplotype phase inference for genome-wide association studies
    Sharon R Browning
    Department of Statistics, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand
    Hum Genet 124:439-50. 2008
  5. pmc Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering
    Sharon R Browning
    Department of Statistics, The University of Auckland, Auckland, New Zealand
    Am J Hum Genet 81:1084-97. 2007
  6. pmc A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals
    Brian L Browning
    Department of Statistics, University of Auckland, Auckland 1142, New Zealand
    Am J Hum Genet 84:210-23. 2009
  7. pmc High-resolution detection of identity by descent in unrelated individuals
    Sharon R Browning
    Department of Statistics, University of Auckland, Auckland, New Zealand
    Am J Hum Genet 86:526-39. 2010
  8. pmc Population structure with localized haplotype clusters
    Sharon R Browning
    Department of Statistics, University of Auckland, Auckland 1142, New Zealand
    Genetics 185:1337-44. 2010
  9. pmc Estimation of pairwise identity by descent from dense genetic marker data in a population sample of haplotypes
    Sharon R Browning
    Department of Statistics, The University of Auckland, Auckland 1142, New Zealand
    Genetics 178:2123-32. 2008
  10. doi request reprint A canine model of inherited myopia: familial aggregation of refractive error in labrador retrievers
    Joanna Black
    Department of Optometry and Vision Science, University of Auckland, Auckland, New Zealand
    Invest Ophthalmol Vis Sci 49:4784-9. 2008

Collaborators

Detail Information

Publications12

  1. pmc Multilocus analysis of GAW15 NARAC chromosome 18 case-control data
    Sharon R Browning
    Department of Statistics, The University of Auckland, Private Bag 92019, Auckland, New Zealand
    BMC Proc 1:S11. 2007
    ..This haplotype was located less than 500 base pairs upstream of the CCBE1 gene. The association was not detected using single-marker tests, but could be found using a variety of multilocus tests...
  2. pmc Multilocus association mapping using variable-length Markov chains
    Sharon R Browning
    Department of Statistics, The University of Auckland, Auckland 92019, New Zealand
    Am J Hum Genet 78:903-13. 2006
    ..I present analyses of two published data sets that show that this approach can have better power than single-marker tests or sliding-window haplotypic tests...
  3. pmc Haplotypic analysis of Wellcome Trust Case Control Consortium data
    Brian L Browning
    Department of Statistics, The University of Auckland, Private Bag 92019, Auckland, New Zealand
    Hum Genet 123:273-80. 2008
    ..In addition, we demonstrate that it is possible to simultaneously phase 16,000 individuals genotyped on genome-wide data (450 K markers) using the Beagle software package...
  4. pmc Missing data imputation and haplotype phase inference for genome-wide association studies
    Sharon R Browning
    Department of Statistics, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand
    Hum Genet 124:439-50. 2008
    ....
  5. pmc Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering
    Sharon R Browning
    Department of Statistics, The University of Auckland, Auckland, New Zealand
    Am J Hum Genet 81:1084-97. 2007
    ..1 days of computing time, with 99% of masked alleles imputed correctly. Our method is implemented in the Beagle software package, which is freely available...
  6. pmc A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals
    Brian L Browning
    Department of Statistics, University of Auckland, Auckland 1142, New Zealand
    Am J Hum Genet 84:210-23. 2009
    ..We present a useful measure of imputation accuracy, allelic R(2), and show that this measure can be estimated accurately from posterior genotype probabilities. Our methods are implemented in version 3.0 of the BEAGLE software package...
  7. pmc High-resolution detection of identity by descent in unrelated individuals
    Sharon R Browning
    Department of Statistics, University of Auckland, Auckland, New Zealand
    Am J Hum Genet 86:526-39. 2010
    ..We detect HBD in 4.7 individuals per 10,000 on average at a given location. Our methodology is implemented in the freely available BEAGLE software package...
  8. pmc Population structure with localized haplotype clusters
    Sharon R Browning
    Department of Statistics, University of Auckland, Auckland 1142, New Zealand
    Genetics 185:1337-44. 2010
    ..Thus, these new measures of F(ST) and haplotype-cluster diversity provide an important new tool for population genetic analysis of high-density SNP data...
  9. pmc Estimation of pairwise identity by descent from dense genetic marker data in a population sample of haplotypes
    Sharon R Browning
    Department of Statistics, The University of Auckland, Auckland 1142, New Zealand
    Genetics 178:2123-32. 2008
    ..This enables detection of pairwise IBD between haplotypes from individuals whose most recent common ancestor lived up to 50 generations ago...
  10. doi request reprint A canine model of inherited myopia: familial aggregation of refractive error in labrador retrievers
    Joanna Black
    Department of Optometry and Vision Science, University of Auckland, Auckland, New Zealand
    Invest Ophthalmol Vis Sci 49:4784-9. 2008
    ..To determine whether the distribution of naturally occurring myopia in Labrador Retrievers has a genetic component...
  11. ncbi request reprint Efficient multilocus association testing for whole genome association studies using localized haplotype clustering
    Brian L Browning
    Department of Statistics, The University of Auckland, Auckland, New Zealand
    Genet Epidemiol 31:365-75. 2007
    ....
  12. ncbi request reprint Case-control single-marker and haplotypic association analysis of pedigree data
    Sharon R Browning
    Genetics Research, GlaxoSmithKline, Research Triangle Park, North Carolina 27709, USA
    Genet Epidemiol 28:110-22. 2005
    ..We demonstrate that our method has power at least as great as that of several competing methods, while offering advantages in the ability to handle missing data and perform haplotypic analysis...