Research Topics
Genomes and Genes
Species | Peter N BlackSummaryAffiliation: University of Auckland Country: New Zealand Publications
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Detail Information
Publications
Relationship between serum 25-hydroxyvitamin d and pulmonary function in the third national health and nutrition examination surveyPeter N Black
Department of Medicine, University of Auckland, Private Bag 92019 Auckland, New Zealand
Chest 128:3792-8. 2005..Low concentrations of vitamin D have been associated with a number of diseases, including osteoporosis, hypertension, and type I diabetes. It is possible that serum concentrations of vitamin D might also influence pulmonary function...- Antibiotics for the treatment of asthmaPeter N Black
Department of Pharmacology and Clinical Pharmacology, University of Auckland, Auckland, New Zealand
Curr Opin Pharmacol 7:266-71. 2007..It is not clear whether any effect that these antibiotics has is a result of antimicrobial actions against organisms such as C. pneumoniae or whether it is due to their anti-inflammatory action... 
How often do physicians review medication charts on ward rounds?Khang Li Looi
Dept of Pharmacology and Clinical Pharmacology, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
BMC Clin Pharmacol 8:9. 2008..The aim of this study was to determine the frequency with which specialist physicians reviewed medication charts during ward rounds...- Differences in the potencies of inhaled steroids are not reflected in the doses prescribed in primary care in New ZealandP N Black
Department of Medicine, University of Auckland, New Zealand
Eur J Clin Pharmacol 56:431-5. 2000..To determine whether the average doses of inhaled beclomethasone, fluticasone and budesonide prescribed in primary care reflect the relative potencies of these medicines... 
Interventions to reduce the frequency of exacerbations of chronic obstructive pulmonary diseaseP N Black
Department of Pharmacology and Clinical Pharmacology, University of Auckland, Auckland, New Zealand
Postgrad Med J 85:141-7. 2009..Other interventions including oral bacterial extracts and self-management programmes warrant further study...- Changes in elastic fibres in the small airways and alveoli in COPDP N Black
Dept of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
Eur Respir J 31:998-1004. 2008..Loss of elastic fibres in small airways may contribute to the development of airflow obstruction in chronic obstructive pulmonary disease... - Role of antibiotics in the management of chronic obstructive pulmonary diseasePeter N Black
Department of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
Expert Rev Respir Med 2:235-43. 2008..Until the full results of these studies are published, it will not be clear if they should be used... - Trial of roxithromycin in subjects with asthma and serological evidence of infection with Chlamydia pneumoniaeP N Black
Auckland Hospital, Auckland, New Zealand
Am J Respir Crit Care Med 164:536-41. 2001..Further studies are necessary to determine whether the lack of sustained benefit is due to failure to eradicate C. pneumoniae... - Dietary intakes of European, Māori, Pacific and Asian adults living in Auckland: the Diabetes, Heart and Health StudyPatricia A Metcalf
Division of Epidemiology and Biostatistics and Department of Statistics, University of Auckland, Auckland, New Zealand
Aust N Z J Public Health 32:454-60. 2008..To compare dietary intakes of European, Māori, Pacific, and Asian men and women living in Auckland... - Prevalence and determinants of cytomegalovirus infection in pre-school childrenTIMOTHY P O'BRIEN
Departments of Paediatrics, University of Auckland, Private Bag 92019, Auckland, New Zealand
J Paediatr Child Health 45:291-6. 2009..The aim of this study is to measure the seroprevalence of cytomegalovirus (CMV) infection in 3.5-year-old children, and identify the determinants of seropositivity... - Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative studyAngharad R Morgan
Discipline of Nutrition, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
BMC Med Genet 11:125. 2010..However, in a large proportion of SGA, no underlying cause is evident, and these individuals may have a larger genetic contribution... - Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary diseaseMervyn J Merrilees
Department of Anatomy with Radiology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand
Respir Res 9:41. 2008..This study aimed to determine if alveoli of patients with mild to moderate COPD contained increased amounts of versican and a corresponding decrease in EBP, and if these changes were correlated with decreases in elastin and FEV1... - The cyclooxygenase-2-765C promoter polymorphism protects against the development of chronic obstructive pulmonary diseaseLian Wu
Department of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
Respir Med 105:506-10. 2011..Susceptibility to Chronic Obstructive Pulmonary Disease (COPD) has a genetic component. We undertook a study to determine if a genetic variant of the gene encoding the cyclooxygenase-2 gene influences the likelihood of developing COPD... - Comparison of different markers of socioeconomic status with cardiovascular disease and diabetes risk factors in the Diabetes, Heart and Health SurveyPatricia A Metcalf
Division of Epidemiology and Biostatistics, School of Population Health, Tamaki Campus, University of Auckland, Private Bag 92019, Auckland, New Zealand
N Z Med J 121:45-56. 2008..To compare different markers of socioeconomic status (SES) with cardiovascular disease (CVD) and diabetes risk factors... - Cushing's syndrome due to interaction between inhaled corticosteroids and itraconazoleMark J Bolland
Department of Endocrinology, Auckland Hospital, Auckland, New Zealand
Ann Pharmacother 38:46-9. 2004..To report a case of an interaction between inhaled corticosteroids and itraconazole causing iatrogenic Cushing's syndrome and provide a review of the relevant literature... - Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary diseasePhillippa Poole
Department of Medicine, University of Auckland, Auckland, New Zealand
Cochrane Database Syst Rev 8:CD001287. 2012..There is a marked difference among countries in terms of prescribing of mucolytics depending on whether or not they are perceived to be effective... - Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary diseasePhillippa Poole
University of Auckland, Private Bag 92019, Auckland, New Zealand
Cochrane Database Syst Rev 2:CD001287. 2010..Mucolytics should be considered for use, through the winter months at least, in patients with moderate or severe COPD in whom inhaled corticosteroids (ICS) are not prescribed... - Oral bacterial vaccines for the prevention of acute exacerbations in chronic obstructive pulmonary disease and chronic bronchitisClaire Arandjus
Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand
Respir Med 100:1671-81. 2006..Further trials are needed before the use of oral vaccines could be considered as part of the routine clinical management of patients with COPD or chronic bronchitis... - Serum lipid levels for a multicultural population in Auckland, New Zealand: results from the Diabetes Heart and Health Survey (DHAH) 2002-2003Dudley Gentles
Department of Epidemiology and Biostatistics, School of Population Health, Tamaki Campus, University of Auckland, Auckland
N Z Med J 120:U2800. 2007..To describe mean serum lipid concentrations for Maori, Pacific people (mostly of Samoan, Tongan, Niuean, or Cook Islands origin), and Others (mostly New Zealand-born Europeans), and to identify risk factors for an adverse lipid profile... - Pro-inflammatory phenotype of COPD fibroblasts not compatible with repair in COPD lungJing Zhang
Department of Pulmonary Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
J Cell Mol Med 16:1522-32. 2012..Versican inhibits assembly of tropoelastin into insoluble elastin and we conclude that the pro-inflammatory phenotype of COPD fibroblasts is not compatible with repair of elastic fibres... - Risk factors for obesity in 7-year-old European children: the Auckland Birthweight Collaborative StudyNikki J Blair
Department of Paediatrics, University of Auckland, Auckland, New Zealand
Arch Dis Child 92:866-71. 2007..To identify risk factors associated with obesity in primary school children, with a particular focus on those which can be modified. To identify critical periods and growth patterns in the development of childhood obesity... - Advanced glycation end products and its receptor (RAGE) are increased in patients with COPDLian Wu
Department of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
Respir Med 105:329-36. 2011..AGEs are proinflammatory and can modify the extracellular matrix. RAGE (Receptor for Advanced Glycation End Products) mediates some of the effects of AGEs... - Effect of education on the recording of medicines on admission to hospitalAmy Hai Yan Chan
Department of Pharmacology and Clinical Pharmacology, University of Auckland, Auckland, New Zealand
J Gen Intern Med 25:537-42. 2010..The inaccurate recording of medicines on admission to hospital is an important cause of medication error. Medication reconciliation has been used to identify and correct these errors... - Lung cancer susceptibility model based on age, family history and genetic variantsRobert P Young
Department of Medicine, Auckland Hospital, Auckland, New Zealand
PLoS ONE 4:e5302. 2009..In a case control association study of healthy smokers and lung cancer cases, we identified genetic markers associated with either susceptibility or protection to lung cancer... - Preventing exacerbations of chronic bronchitis and COPD: therapeutic potential of mucolytic agentsPhillippa J Poole
University of Auckland, Auckland, New Zealand
Am J Respir Med 2:367-70. 2003..Those with more frequent and severe exacerbations appear to have the most to gain... - Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary diseaseJimmy Chong
University of Auckland, Auckland, New Zealand
Cochrane Database Syst Rev 5:CD002309. 2011..Roflumilast and cilomilast are oral phosphodiesterase 4 (PDE(4)) inhibitors proposed to reduce the airway inflammation and bronchoconstriction seen in COPD... - The effect of telithromycin in acute exacerbations of asthmaSebastian L Johnston
Department of Respiratory Medicine, National Heart and Lung Institute and Wright Fleming Institute of Infection and Immunity, National Heart and Lung Institute, Imperial College London, United Kingdom
N Engl J Med 354:1589-600. 2006..We conducted a double-blind, randomized, placebo-controlled study to evaluate the efficacy of telithromycin in patients with acute exacerbations of asthma... - Reducing asthma treatmentPeter N Black
N Engl J Med 357:504; author reply 505-6. 2007 - Short sleep duration in middle childhood: risk factors and consequencesGillian M Nixon
Ritchie Centre obr Baby Health Research, Monash Institute of Medical Research, Monash University, Melbourne, Australia
Sleep 31:71-8. 2008..To measure sleep duration in 7-year-old children; identify the determinants of sleep duration; and assess the association between short sleep duration and obesity, cognitive functioning, and behaviour...