Istvan M Abraham

Summary

Affiliation: University of Otago
Country: New Zealand

Publications

  1. ncbi request reprint Neuroprotective effects of non-classical estrogen-like signaling activators: from mechanism to potential implications
    Andrea Kwakowsky
    Centre for Neuroendocrinology and Department of Physiology, University of Otago, Lindo Ferguson Building, 270 Great King Street, PO Box 913, 9054, Dunedin, New Zealand
    CNS Neurol Disord Drug Targets 12:1219-25. 2013
  2. doi request reprint Action of estrogen on survival of basal forebrain cholinergic neurons: promoting amelioration
    Istvan M Abraham
    Centre for Neuroendocrinology, Department of Physiology, University of Otago, Dunedin, New Zealand
    Psychoneuroendocrinology 34:S104-12. 2009
  3. doi request reprint The role of cAMP response element-binding protein in estrogen negative feedback control of gonadotropin-releasing hormone neurons
    Andrea Kwakowsky
    Centre for Neuroendocrinology and Department of Physiology, Otago School of Medical Sciences, University of Otago, 9054 Dunedin, New Zealand
    J Neurosci 32:11309-17. 2012
  4. doi request reprint Postlesion estradiol treatment increases cortical cholinergic innervations via estrogen receptor-α dependent nonclassical estrogen signaling in vivo
    Zsombor Koszegi
    Centre for Neuroendocrinology and Department of Physiology, Otago School of Medical Sciences, University of Otago, 9054 Dunedin, New Zealand
    Endocrinology 152:3471-82. 2011
  5. doi request reprint Estradiol acts directly and indirectly on multiple signaling pathways to phosphorylate cAMP-response element binding protein in GnRH neurons
    Rachel Y Cheong
    Centre for Neuroendocrinology and Department of Physiology, University of Otago, Lindo Ferguson Building, 270 Great King Street, P O Box 913, Dunedin 9054, New Zealand
    Endocrinology 153:3792-803. 2012
  6. doi request reprint Non-classical effects of estradiol on cAMP responsive element binding protein phosphorylation in gonadotropin-releasing hormone neurons: Mechanisms and role
    Andrea Kwakowsky
    Centre for Neuroendocrinology, Department of Physiology, Otago School of Medical Sciences, University of Otago, Dunedin 9054, New Zealand
    Front Neuroendocrinol 35:31-41. 2014

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Neuroprotective effects of non-classical estrogen-like signaling activators: from mechanism to potential implications
    Andrea Kwakowsky
    Centre for Neuroendocrinology and Department of Physiology, University of Otago, Lindo Ferguson Building, 270 Great King Street, PO Box 913, 9054, Dunedin, New Zealand
    CNS Neurol Disord Drug Targets 12:1219-25. 2013
    ..In addition, the pitfalls and future aspects of "non-classical"-line activators and its clinical relevance will also be discussed. ..
  2. doi request reprint Action of estrogen on survival of basal forebrain cholinergic neurons: promoting amelioration
    Istvan M Abraham
    Centre for Neuroendocrinology, Department of Physiology, University of Otago, Dunedin, New Zealand
    Psychoneuroendocrinology 34:S104-12. 2009
    ..In addition, clinical relevance, pitfalls and future aspects of estrogen therapy on basal forebrain cholinergic neurons will be discussed...
  3. doi request reprint The role of cAMP response element-binding protein in estrogen negative feedback control of gonadotropin-releasing hormone neurons
    Andrea Kwakowsky
    Centre for Neuroendocrinology and Department of Physiology, Otago School of Medical Sciences, University of Otago, 9054 Dunedin, New Zealand
    J Neurosci 32:11309-17. 2012
    ..These observations implicate CREB within the GnRH neuron as an important target for E2's negative feedback actions. They also indicate that the rapid modulation of CREB by E2 is of physiological significance in the CNS...
  4. doi request reprint Postlesion estradiol treatment increases cortical cholinergic innervations via estrogen receptor-α dependent nonclassical estrogen signaling in vivo
    Zsombor Koszegi
    Centre for Neuroendocrinology and Department of Physiology, Otago School of Medical Sciences, University of Otago, 9054 Dunedin, New Zealand
    Endocrinology 152:3471-82. 2011
    ..They also reveal the critical role of nonclassical estrogen signaling via estrogen receptor-α and protein kinase A-MAPK pathways in E2-induced restorative action in the cholinergic system in vivo...
  5. doi request reprint Estradiol acts directly and indirectly on multiple signaling pathways to phosphorylate cAMP-response element binding protein in GnRH neurons
    Rachel Y Cheong
    Centre for Neuroendocrinology and Department of Physiology, University of Otago, Lindo Ferguson Building, 270 Great King Street, P O Box 913, Dunedin 9054, New Zealand
    Endocrinology 153:3792-803. 2012
    ..Intriguingly, these effects of E2 are dependent upon both direct ERβ mechanisms as well as indirect actions mediated by afferent inputs to GnRH neurons...
  6. doi request reprint Non-classical effects of estradiol on cAMP responsive element binding protein phosphorylation in gonadotropin-releasing hormone neurons: Mechanisms and role
    Andrea Kwakowsky
    Centre for Neuroendocrinology, Department of Physiology, Otago School of Medical Sciences, University of Otago, Dunedin 9054, New Zealand
    Front Neuroendocrinol 35:31-41. 2014
    ..Secondly, this review considers the receptors and signaling network that regulates estradiol's action on pCREB within GnRH neurons and finally it summarizes the physiological significance of CREB to estrogen feedback. ..