University of Otago

..Diets that focus on substantially altering macronutrient distribution rather than energy restriction are promising alternatives, but have generally included large amounts of protein, fiber or fat...

..Together, these findings provide compelling evidence for a deficiency in cell-to-cell adhesion being sufficient to initiate diffuse gastric cancer in the absence of hyperproliferation and beta-catenin activation...

..To determine the incidence of bleeding associated with the use of enoxaparin in NSTEACS at Dunedin Public Hospital (DPH) and to identify bleeding risk factors in this patient group...

..These data suggest that the late-phase LTP is not mediated by an overt increase in the AMPAR content of perforant path synapses. The increase in surface expression NMDARs may influence thresholds for future plasticity events...

..Through these activities, the New Zealand IMMP provides an ongoing contribution to safety in the use of medicines...

..There are a number of potentially confounding factors that may affect relationships found between the existence of home hazards and injury occurrence. These need to be taken into account when future evaluations are planned...

..The posterior estimates are more precise and generally have lower mean-squared error than traditional data summaries, and yet are not strictly constrained to follow a posited prior model form...

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..The aim of this study was to examine the relationship between personality factors assessed during adolescence and persistent risky driving behavior and traffic crash involvement among young adults...

..Here, the prospects offered by both approaches, as well as their limitations, are highlighted...

..In this short communication we consider some of the implications relating to predictive genetic testing in the public domain...

..The present study tested that association...

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..A freely available computer program, called MIXTEST, can be used both to carry out the likelihood ratio test and to conduct simulations evaluating the performance of the test within various settings...

..That is, a rapid deterioration of performance after receiving feedback that an error was made on the previous task. We aimed to examine this phenomenon in unmedicated, depressed outpatients...

..Clinicians need to be aware of how to identify and manage patients for whom beta-agonist treatment is a problem rather than a solution. They constitute a small but important subgroup of patients with difficult asthma...

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..To describe and compare how men and health professionals perceive men's health and health care...

..However, policy recommendations are important since they have the potential to create environments which are conducive to the behavioural changes required for improved nutrition...

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..The purpose of this study was to determine the effect of different levels of exercise intensity on the timed finger-to-nose (FTN) task, a measure of upper limb coordination included in the Sport Concussion Assessment Tool (SCAT2)...

..Many studies thus far have suffered from design limitations and small sample sizes. This study aimed to compare compliance with C-Flex and CPAP, as well as analyzing objective and subjective sleepiness and vigilance...

..To develop an approach for achieving value for money in rehabilitation based on dynamic prioritisation of access to services according to individual capacity to benefit...

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..As the reaction occurs strictly with the thiolate, this oxidant should selectively target proteins containing low pK(a) thiols...

..The decreased viability of Npr1(-/-)embryos may result from a combination of cardiomegaly and dysregulated Cx43 protein affecting cardiac contractility...

..The purpose of this paper is to explore pharmaceutical manufacturers', distributors' and providers' perceptions of drug quality in South Africa and how they ensure the quality of drugs during the distribution process...

..TPI proved to be highly suitable to detect non-homogeneities in the drug layer and polymeric film coating...

..Measurement of oculomotor function may be of value in PCS cases with a high symptom load but an otherwise unremarkable assessment profile. Routine oculomotor testing should be feasible in centres with existing access to this technology...

..Kaplan-Meier survival curves at 13 years showed survival of 96.8% (95% confidence interval 90.2 to 99.0) for revision for any cause and of 95.7% (95% confidence interval 88.6 to 98.4) for any acetabular re-operation...

..We aimed to develop and validate a patient questionnaire for determining the effect of gallstone disease on quality of life (QOL) and evaluate its potential role in appraising prioritization and outcomes from surgery...

..To determine the proportion of prescriptions for antibiotics which were unsubsidised, in one town in one year, and to use this to develop a model which could be used to estimate the number of unsubsidised prescriptions...

..These findings suggest that impairment of chondrocytic formation and differentiation is the major pathogenesis of MOPD type II...

..Some of the newly identified elements appear to be structurally intact and may still be active. The identification of this group challenges some previously held beliefs concerning the structure and evolution of LTR retrotransposons...

..5/100,000) which is consistent with similar data from South Africa and the USA. The rates of fracture in Maori (68.1/100,000) were approximately twice those of Pacific Islanders (37/100,000) or other ethnic groups (34.2/100,000)...

..no. 15 (Parassitologia 22 (1980) 1). As opposed to the latter species, Maritrema subdolum does not express the appropriate cercarial behaviour for hitch-hiking...

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..This suggests that members of the Tf1/sushi group are present as functional elements (or incorporated as partial elements into host genes) in diverse vertebrate lineages...

..The authors conclude that a dual task becomes a single task, and interlimb interference is reduced, when the spatial patterns produced by the 2 hands form a geometric arrangement that can be conceptualized as a unified representation...

..Exposure to low temperatures may occur within the carcass of the host and this may be of epidemiological significance if the parasite can be transmitted via the consumption of the carcass...

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..These results further validate K20 as a marker by providing greater certainty that what is being detected represents occult metastatic disease...

..To examine risk factors for onset of low back pain (LBP) in healthcare workers...

..This article outlines the relative merits of syrup of ipecacuanha and activated charcoal, and concludes that the latter is preferable in many respects. Details of its appropriate administration are discussed...

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..To test the hypothesis that the 1990-91 social and economic policy changes in New Zealand were associated with a subsequent increase in socioeconomic and ethnic inequalities in the dental caries experience of five-year-old children...

..To describe differences between registered and unregistered patients in New Zealand general practice and assess patient registers prior to enrollment in primary health organisations (PHOs)...

..3) To determine the degree to which under-reporting of serious crashes involving cyclists and motor vehicles on public roads is associated with various demographic, environmental, and injury factors...

..To assess the influence of infant breast feeding on C reactive protein (CRP), a marker of low grade inflammation associated with cardiovascular mortality independent of serum cholesterol concentrations...

..Moreover, the persistent expression of PRL-R(L) in arcuate neuroendocrine circuits suggests that PRL-R-mediated signalling continues to be important in these neurones during lactation...

..Possible patterns of lymphocyte sensitization and trafficking are discussed...

..However, we did detect a small but statistically significant upregulation of the anti-apoptotic protein Bcl-2 in the contralateral VNC at 10 h post-UL...

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..Philopatry has produced multiple reproductive stocks of this commercially important shark species throughout the range of this study...

..These findings may be related to the observation that patients with vestibular deficits experience a high incidence of depression and anxiety disorders...

..neoformans/C. gattii group. It is therefore probable that the C. neoformans/C. gattii mini-intein was derived from horizontal transfer in which C. laurentii or another intein-containing species was the source...

..These results are consistent with the induction of tuberculin-specific cell-mediated immune responses...

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..The current study aims to describe participation and interest in 18 selected popular sports among a large sample of New Zealand adolescents with the goal of identifying opportunities for increasing youth participation in physical activity...

..The experienced practitioner may intuitively include tooth and pulp morphology in treatment planning, but this appears not to be taught or documented in textbooks...

..The presence of a well-established mollusc colony on the vault allowed us to establish a minimum elapsed time since death. Such a cross-disciplinary co-operative study is of great advantage in expediting a satisfactory conclusion...

..S. pyogenes, Streptococcus gordonii, Streptococcus oralis, S. mutans, and Streptococcus rattus has been evaluated...

..Findings from the housing cohort would be used to guide advice about reducing influenza transmission in households, particularly in terms of crowding levels and exposure to active and passive smoking. ..

..This project will increase our understanding of efflux pump structure and function and identify pump inhibitors that could lead to new therapies for patients with opportunistic fungal infections. ..