William A Laing

Summary

Affiliation: The Horticulture and Food Research Institute of New Zealand
Country: New Zealand

Publications

  1. pmc The missing step of the L-galactose pathway of ascorbate biosynthesis in plants, an L-galactose guanyltransferase, increases leaf ascorbate content
    William A Laing
    Horticultural and Food Research Institute of New Zealand, PB 92160, Auckland 1142, New Zealand
    Proc Natl Acad Sci U S A 104:9534-9. 2007
  2. pmc A highly specific L-galactose-1-phosphate phosphatase on the path to ascorbate biosynthesis
    William A Laing
    Gene Technologies Sector, Horticultural and Food Research Institute of New Zealand, Ltd, PB 92169, Auckland, New Zealand
    Proc Natl Acad Sci U S A 101:16976-81. 2004
  3. doi request reprint Enhancing ascorbate in fruits and tubers through over-expression of the L-galactose pathway gene GDP-L-galactose phosphorylase
    Sean Bulley
    The New Zealand Institute for Plant and Food Research Limited, Auckland, New Zealand
    Plant Biotechnol J 10:390-7. 2012
  4. pmc Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening
    Ross N Crowhurst
    The Horticultural and Food Research Institute of New Zealand, PB 92169, Auckland, New Zealand
    BMC Genomics 9:351. 2008
  5. doi request reprint Effects of kiwifruit extracts on colonic gene and protein expression levels in IL-10 gene-deficient mice
    Shelley J Edmunds
    Food Innovation, Plant and Food Research Limited, Auckland, New Zealand
    Br J Nutr 108:113-29. 2012
  6. doi request reprint MYB transcription factors that colour our fruit
    Andrew C Allan
    HortResearch, Mt Albert Research Centre, Private Bag 92169, Auckland, New Zealand
    Trends Plant Sci 13:99-102. 2008
  7. doi request reprint Ethylene-regulated (methylsulfanyl)alkanoate ester biosynthesis is likely to be modulated by precursor availability in Actinidia chinensis genotypes
    Catrin S Günther
    The New Zealand Institute for Plant and Food Research Ltd, Private Bag 92169, Auckland 1142, New Zealand
    J Plant Physiol 168:629-38. 2011
  8. ncbi request reprint Identification and characterisation of proteinase inhibitors and their genes from seeds of apple (Malus domestica)
    Stuart N Ryan
    Horticulture and Food Research Institute of New Zealand, Private Bag 92169, Auckland, New Zealand
    J Biochem 134:31-42. 2003
  9. doi request reprint Unusual immuno-modulatory triterpene-caffeates in the skins of russeted varieties of apples and pears
    Christelle M Andre
    The New Zealand Institute for Plant and Food Research Limited, Mt Albert Research Centre, Private Bag 92 169, Auckland 1142, New Zealand
    J Agric Food Chem 61:2773-9. 2013
  10. ncbi request reprint The squash aspartic proteinase inhibitor SQAPI is widely present in the cucurbitales, comprises a small multigene family, and is a member of the phytocystatin family
    John T Christeller
    Horticulture and Food Research Institute, Private Bag 11030, Palmerston North, New Zealand
    J Mol Evol 63:747-57. 2006

Detail Information

Publications19

  1. pmc The missing step of the L-galactose pathway of ascorbate biosynthesis in plants, an L-galactose guanyltransferase, increases leaf ascorbate content
    William A Laing
    Horticultural and Food Research Institute of New Zealand, PB 92160, Auckland 1142, New Zealand
    Proc Natl Acad Sci U S A 104:9534-9. 2007
    ..Transient expression of this A. chinensis gene in tobacco leaves resulted in a >3-fold increase in leaf ascorbate as well as a 50-fold increase in GDP-L-galactose-D-mannose-1-phosphate guanyltransferase activity...
  2. pmc A highly specific L-galactose-1-phosphate phosphatase on the path to ascorbate biosynthesis
    William A Laing
    Gene Technologies Sector, Horticultural and Food Research Institute of New Zealand, Ltd, PB 92169, Auckland, New Zealand
    Proc Natl Acad Sci U S A 101:16976-81. 2004
    ..The data are discussed in terms of the pathway to ascorbate biosynthesis in plants...
  3. doi request reprint Enhancing ascorbate in fruits and tubers through over-expression of the L-galactose pathway gene GDP-L-galactose phosphorylase
    Sean Bulley
    The New Zealand Institute for Plant and Food Research Limited, Auckland, New Zealand
    Plant Biotechnol J 10:390-7. 2012
    ..In both strawberry and tomato, an increase in polyphenolic content was associated with increased ascorbate. These results show that GGP can be used to raise significantly ascorbate concentration in commercially significant edible crops...
  4. pmc Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening
    Ross N Crowhurst
    The Horticultural and Food Research Institute of New Zealand, PB 92169, Auckland, New Zealand
    BMC Genomics 9:351. 2008
    ..To increase our understanding of the genetic diversity and gene-based control of these key traits in Actinidia, we have produced a collection of 132,577 expressed sequence tags (ESTs)...
  5. doi request reprint Effects of kiwifruit extracts on colonic gene and protein expression levels in IL-10 gene-deficient mice
    Shelley J Edmunds
    Food Innovation, Plant and Food Research Limited, Auckland, New Zealand
    Br J Nutr 108:113-29. 2012
    ....
  6. doi request reprint MYB transcription factors that colour our fruit
    Andrew C Allan
    HortResearch, Mt Albert Research Centre, Private Bag 92169, Auckland, New Zealand
    Trends Plant Sci 13:99-102. 2008
    ..These findings lead the way to new approaches in the breeding and biotechnological development of fruit with new colour patterns...
  7. doi request reprint Ethylene-regulated (methylsulfanyl)alkanoate ester biosynthesis is likely to be modulated by precursor availability in Actinidia chinensis genotypes
    Catrin S Günther
    The New Zealand Institute for Plant and Food Research Ltd, Private Bag 92169, Auckland 1142, New Zealand
    J Plant Physiol 168:629-38. 2011
    ..chinensis kiwifruit and a close connection between (methylsulfanyl)alkanoate ester formation and ethylene synthesis in plants is proposed. Finally, a possible biosynthetic pathway is presented...
  8. ncbi request reprint Identification and characterisation of proteinase inhibitors and their genes from seeds of apple (Malus domestica)
    Stuart N Ryan
    Horticulture and Food Research Institute of New Zealand, Private Bag 92169, Auckland, New Zealand
    J Biochem 134:31-42. 2003
    ..The relationship of these inhibitors with those of other species is discussed...
  9. doi request reprint Unusual immuno-modulatory triterpene-caffeates in the skins of russeted varieties of apples and pears
    Christelle M Andre
    The New Zealand Institute for Plant and Food Research Limited, Mt Albert Research Centre, Private Bag 92 169, Auckland 1142, New Zealand
    J Agric Food Chem 61:2773-9. 2013
    ....
  10. ncbi request reprint The squash aspartic proteinase inhibitor SQAPI is widely present in the cucurbitales, comprises a small multigene family, and is a member of the phytocystatin family
    John T Christeller
    Horticulture and Food Research Institute, Private Bag 11030, Palmerston North, New Zealand
    J Mol Evol 63:747-57. 2006
    ..This appears to be the first instance of a cystatin being recruited as a proteinase inhibitor of another proteinase family...
  11. doi request reprint Quantification of folate in fruits and vegetables: A fluorescence-based homogeneous assay
    Harry Martin
    New Zealand Institute for Plant and Food Research, New Zealand
    Anal Biochem 402:137-45. 2010
    ..These data are similar to published values. However, the assay will not detect 5-formyltetrahydrofolate which is a significant constituent of the total folate in lettuce, spinach, carrot, and peppers...
  12. doi request reprint Anti-inflammatory procyanidins and triterpenes in 109 apple varieties
    Christelle M Andre
    New Zealand Institute for Plant and Food Research Limited, Mt Albert Research Centre, Private Bag 92 169, Auckland 1142, New Zealand
    J Agric Food Chem 60:10546-54. 2012
    ..This study provides new insights into how apple genetic diversity could be used to alleviate inflammation...
  13. ncbi request reprint Purification and characterization of phytocystatins from kiwifruit cortex and seeds
    Maysoon Rassam
    Gene Technologies, The Horticultural and Food Research Institute of New Zealand, PB 92169, Auckland, New Zealand
    Phytochemistry 65:19-30. 2004
    ..This is the first report of phytocystatins from the Ericales...
  14. doi request reprint Dietary flavonoids from modified apple reduce inflammation markers and modulate gut microbiota in mice
    Richard V Espley
    The New Zealand Institute for Plant and Food Research Limited PFR, Auckland, New Zealand
    J Nutr 144:146-54. 2014
    ..01). In summary, high-flavonoid apple was associated with decreases in some inflammation markers and changes in gut microbiota when fed to healthy mice. ..
  15. doi request reprint Kiwifruit extracts inhibit cytokine production by lipopolysaccharide-activated macrophages, and intestinal epithelial cells isolated from IL10 gene deficient mice
    Shelley J Edmunds
    Food Innovation, The New Zealand Institute for Plant and Food Research Ltd, Auckland 1142, New Zealand
    Cell Immunol 270:70-9. 2011
    ..These results suggest that kiwifruit extracts have significant anti-inflammatory activity relevant to IBD. We suggest that the Il10(-/-) mouse is a suitable model for further study of these compounds...
  16. pmc Analyses of expressed sequence tags from apple
    Richard D Newcomb
    Horticultural and Food Research Institute of New Zealand Limited, Mt Albert Research Centre, Auckland, New Zealand
    Plant Physiol 141:147-66. 2006
    ..This resource paves the way for a concerted functional genomics effort in this important temperate fruit crop...
  17. ncbi request reprint Physiological and biochemical leaf and tree responses to crop load in apple
    Jens N Wünsche
    HortResearch, Hawke s Bay Research Centre, Private Bag 1401, Havelock North, New Zealand
    Tree Physiol 25:1253-63. 2005
    ..Increases in xanthophyll cycle carotenoids mediated non-radiative thermal energy dissipation in non-cropping trees, providing increased capacity for photoprotection but reducing photochemical efficiency...
  18. ncbi request reprint Analysis of the interaction between the aspartic peptidase inhibitor SQAPI and aspartic peptidases using surface plasmon resonance
    Peter C Farley
    Institute of Molecular Biosciences, Massey University, Palmerston North, New Zealand
    J Mol Recognit 15:135-44. 2002
    ..albicans rSap1 and Sap2 isoenzymes (inhibition constants 25 and 400 nM, respectively) was, in each case, characterized by a larger dissociation rate constant...
  19. ncbi request reprint The expression of a mammalian proteinase inhibitor, bovine spleen trypsin inhibitor in tobacco and its effects on Helicoverpa armigera larvae
    John T Christeller
    The Horticulture and Food Research Institute of New Zealand, Palmerston North Research Centre
    Transgenic Res 11:161-73. 2002
    ..Activities of leucine aminopeptidase and elastase-like chymotrypsin remained unaltered. The use of SI as an insect resistance factor is discussed...