Ralph A Stewart

Summary

Country: New Zealand

Publications

  1. pmc A mHealth cardiac rehabilitation exercise intervention: findings from content development studies
    Leila Pfaeffli
    Clinical Trials Research Unit, University of Auckland, Auckland, New Zealand
    BMC Cardiovasc Disord 12:36. 2012
  2. doi request reprint Thrombosis on a Mechanical Aortic Valve whilst Anti-coagulated With Dabigatran
    Ralph A H Stewart
    Department of Cardiology, Auckland City Hospital, Auckland, New Zealand
    Heart Lung Circ 21:53-5. 2012
  3. pmc HEART: heart exercise and remote technologies: a randomized controlled trial study protocol
    Ralph Maddison
    Clinical Trials Research Unit, University of Auckland, Glen Innes, Auckland 1121, New Zealand
    BMC Cardiovasc Disord 11:26. 2011
  4. ncbi request reprint Differences in cardiovascular mortality between Australia and New Zealand according to socioeconomic status: findings from the Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study
    Ralph A Stewart
    Green Lane Cardiovascular Unit, Auckland City Hospital, Private Bag 92024, Auckland 1030, New Zealand
    N Z Med J 121:11-23. 2008
  5. doi request reprint A randomized trial of the aldosterone-receptor antagonist eplerenone in asymptomatic moderate-severe aortic stenosis
    Ralph A H Stewart
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Am Heart J 156:348-55. 2008
  6. ncbi request reprint White blood cell count predicts reduction in coronary heart disease mortality with pravastatin
    Ralph A H Stewart
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Circulation 111:1756-62. 2005
  7. doi request reprint Pilot study to assess the influence of beta-blockade on mitral regurgitant volume and left ventricular work in degenerative mitral valve disease
    Ralph A H Stewart
    Green Lane Cardiovascular Service, Auckland City Hospital, Level 3, Bldg 32, Private Bag 92 189, Auckland 1030, New Zealand
    Circulation 118:1041-6. 2008
  8. ncbi request reprint Clinical trials in heart valve disease
    Ralph A H Stewart
    Cardiology Department, Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Curr Opin Cardiol 24:279-87. 2009
  9. ncbi request reprint Depression and cardiovascular morbidity and mortality: cause or consequence?
    Ralph A H Stewart
    Green Lane Hospital, Auckland, New Zealand
    Eur Heart J 24:2027-37. 2003
  10. doi request reprint Predicting benefit from statins by C-reactive protein, LDL-cholesterol or absolute cardiovascular risk
    Ralph A H Stewart
    Cardiology Department, Auckland City Hospital, New Zealand
    Future Cardiol 5:231-6. 2009

Collaborators

Detail Information

Publications39

  1. pmc A mHealth cardiac rehabilitation exercise intervention: findings from content development studies
    Leila Pfaeffli
    Clinical Trials Research Unit, University of Auckland, Auckland, New Zealand
    BMC Cardiovasc Disord 12:36. 2012
    ..The aim of this paper is to present the content development process for a mHealth (mobile phone and internet-based) cardiac rehabilitation (CR) exercise intervention...
  2. doi request reprint Thrombosis on a Mechanical Aortic Valve whilst Anti-coagulated With Dabigatran
    Ralph A H Stewart
    Department of Cardiology, Auckland City Hospital, Auckland, New Zealand
    Heart Lung Circ 21:53-5. 2012
    ..This case report describes a patient with a St Jude aortic valve replacement who suffered valve thrombosis and an embolic stroke when anti-coagulated with the direct thrombin inhibitor dabigatran etexilate...
  3. pmc HEART: heart exercise and remote technologies: a randomized controlled trial study protocol
    Ralph Maddison
    Clinical Trials Research Unit, University of Auckland, Glen Innes, Auckland 1121, New Zealand
    BMC Cardiovasc Disord 11:26. 2011
    ..This paper outlines the rationale and methods of the trial...
  4. ncbi request reprint Differences in cardiovascular mortality between Australia and New Zealand according to socioeconomic status: findings from the Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study
    Ralph A Stewart
    Green Lane Cardiovascular Unit, Auckland City Hospital, Private Bag 92024, Auckland 1030, New Zealand
    N Z Med J 121:11-23. 2008
    ..This study describes differences in cardiovascular risk factors and cardiovascular mortality in Australians and New Zealanders with stable coronary artery disease stratified by socioeconomic status...
  5. doi request reprint A randomized trial of the aldosterone-receptor antagonist eplerenone in asymptomatic moderate-severe aortic stenosis
    Ralph A H Stewart
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Am Heart J 156:348-55. 2008
    ..Effects of eplerenone on LV diastolic function and progression of valve stenosis were also evaluated...
  6. ncbi request reprint White blood cell count predicts reduction in coronary heart disease mortality with pravastatin
    Ralph A H Stewart
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Circulation 111:1756-62. 2005
    ....
  7. doi request reprint Pilot study to assess the influence of beta-blockade on mitral regurgitant volume and left ventricular work in degenerative mitral valve disease
    Ralph A H Stewart
    Green Lane Cardiovascular Service, Auckland City Hospital, Level 3, Bldg 32, Private Bag 92 189, Auckland 1030, New Zealand
    Circulation 118:1041-6. 2008
    ..The aim of this pilot study was to determine the short-term effects of a beta-blocker on mitral regurgitant volume and LV work in these patients...
  8. ncbi request reprint Clinical trials in heart valve disease
    Ralph A H Stewart
    Cardiology Department, Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Curr Opin Cardiol 24:279-87. 2009
    ..To summarize evidence from clinical trials of heart valve disease and identify areas where further trials are needed...
  9. ncbi request reprint Depression and cardiovascular morbidity and mortality: cause or consequence?
    Ralph A H Stewart
    Green Lane Hospital, Auckland, New Zealand
    Eur Heart J 24:2027-37. 2003
    ..This study assessed whether depressive symptoms were associated with adverse outcomes in people with a history of an acute coronary syndrome, and evaluated possible explanations for such an association...
  10. doi request reprint Predicting benefit from statins by C-reactive protein, LDL-cholesterol or absolute cardiovascular risk
    Ralph A H Stewart
    Cardiology Department, Auckland City Hospital, New Zealand
    Future Cardiol 5:231-6. 2009
    ..Targeting statin treatment based on LDL-cholesterol alone will not provide an optimal risk reduction for many individuals...
  11. doi request reprint Left ventricular systolic and diastolic function assessed by tissue Doppler imaging and outcome in asymptomatic aortic stenosis
    Ralph A H Stewart
    Green Lane Cardiovascular Research, Auckland City Hospital, Auckland, New Zealand
    Eur Heart J 31:2216-22. 2010
    ..This study aimed to determine whether tissue Doppler measures of LV systolic and/or diastolic function or echocardiographic LV hypertrophy are useful for risk stratifying asymptomatic patients with severe calcific AS...
  12. doi request reprint The role of lipoprotein-associated phospholipase a₂ as a marker and potential therapeutic target in atherosclerosis
    Ralph A H Stewart
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, 1030, New Zealand
    Curr Atheroscler Rep 13:132-7. 2011
    ..Two large phase III clinical trials that are currently in progress will determine whether darapladib will reduce the risk of myocardial infarction, stroke, and cardiovascular death by stabilizing atherosclerotic plaques...
  13. doi request reprint Clinical trials of direct thrombin and factor Xa inhibitors in atrial fibrillation
    Ralph Ah Stewart
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Curr Opin Cardiol 26:294-9. 2011
    ..To review the large phase 3 clinical trials that compare direct thrombin or factor Xa inhibitors with dose-adjusted warfarin in patients with atrial fibrillation who have an increased risk of stroke...
  14. doi request reprint Relationship between QRS duration and left ventricular mass and volume in patients at high cardiovascular risk
    Ralph A Stewart
    Green Lane Cardiovascular Service, Auckland City Hospital, Private Bag 92024, Auckland 1030, New Zealand
    Heart 97:1766-70. 2011
    ..To evaluate potential mechanisms, we examined in this study the relationship between QRS duration and left ventricular (LV) mass and LV end systolic and end diastolic volume in patients with known CV disease or high-risk diabetes...
  15. doi request reprint Elevated B-type natriuretic peptide despite normal left ventricular function on rest and exercise stress echocardiography in mitral regurgitation
    Andrew J Kerr
    Department of Cardiology, Middlemore Hospital, Hospital Road, Private Bag 93311, Otahuhu, Auckland, New Zealand
    Eur Heart J 29:363-70. 2008
    ..To determine whether elevated B-type natriuretic peptide (BNP) predicts left ventricular (LV) contractile dysfunction on exercise stress echocardiography in patients with severe mitral regurgitation (MR)...
  16. ncbi request reprint Patients with prolonged ischemic chest pain and presumed-new left bundle branch block have heterogeneous outcomes depending on the presence of ST-segment changes
    Cheuk Kit Wong
    Cardiovascular Research Unit, Green Lane Hospital, Auckland, New Zealand
    J Am Coll Cardiol 46:29-38. 2005
    ....
  17. pmc Mapping of mitral regurgitant defects by cardiovascular magnetic resonance in moderate or severe mitral regurgitation secondary to mitral valve prolapse
    Ruvin S Gabriel
    Department of Cardiology, Middlemore Hospital, Auckland, New Zealand
    J Cardiovasc Magn Reson 10:16. 2008
    ..We assessed whether cardiovascular magnetic resonance (CMR) could accurately identify prolapsing or flail mitral valve leaflets and regurgitant jet direction in patients with known moderate or severe mitral regurgitation...
  18. pmc Longitudinal left ventricular contractile dysfunction after exercise in aortic stenosis
    Niels C Van Pelt
    Department of Cardiology, Middlemore Hospital, Auckland, New Zealand
    Heart 93:732-8. 2007
    ..To determine whether longitudinal left ventricular systolic function measured by Doppler tissue imaging (DTI) after exercise can identify early left ventricular dysfunction in asymptomatic patients with moderate-severe aortic stenosis...
  19. ncbi request reprint Plasma natriuretic peptide levels increase with symptoms and severity of mitral regurgitation
    Timothy M Sutton
    Cardiology Department, Middlemore Hospital, Auckland, New Zealand
    J Am Coll Cardiol 41:2280-7. 2003
    ..This paper will describe associations between plasma natriuretic peptide levels and the severity and symptoms of mitral regurgitation (MR)...
  20. ncbi request reprint Effects of exercise training on 5 inflammatory markers associated with cardiovascular risk
    Christopher J K Hammett
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Am Heart J 151:367.e7-367.e16. 2006
    ....
  21. ncbi request reprint Initial Q waves accompanying ST-segment elevation at presentation of acute myocardial infarction and 30-day mortality in patients given streptokinase therapy: an analysis from HERO-2
    Cheuk Kit Wong
    Cardiovascular Research Unit, Green Lane Hospital, Auckland, New Zealand
    Lancet 367:2061-7. 2006
    ..Our aim was to assess whether the presence or absence of Q waves at presentation could be used as an indicator of the duration of acute myocardial infarction and predict mortality...
  22. ncbi request reprint Is it time to stop treating dyslipidaemia with fibrates?
    Jocelyne R Benatar
    Cardiovascular Research Unit, Green Lane Clinical Centre, Green Lane, Auckland
    N Z Med J 120:U2706. 2007
    ..To determine whether evidence from randomised clinical trials supports the use of fibrates to reduce non-fatal and fatal cardiovascular events in patients with dyslipidaemia...
  23. ncbi request reprint Early ST-segment recovery, infarct artery blood flow, and long-term outcome after acute myocardial infarction
    John K French
    Cardiovascular Research Unit, Cardiology Department, Green Lane Hospital, Auckland, New Zealand
    Am Heart J 143:265-71. 2002
    ..Early resolution of ST-segment deviation (ST recovery) on the postthrombolytic electrocardiograms and restoration of "normal" blood flow in the infarct-related artery are associated with improved outcomes after myocardial infarction (MI)...
  24. ncbi request reprint Associations between plasma natriuretic peptide levels, symptoms, and left ventricular function in patients with chronic aortic regurgitation
    Ivor L Gerber
    Cardiology Department, Green Lane Hospital, Auckland 1030 32, New Zealand
    Am J Cardiol 92:755-8. 2003
    ..In patients with chronic aortic regurgitation, measurement of natriuretic peptide levels may provide information on left ventricular function in addition to echocardiography...
  25. ncbi request reprint Usefulness of serial measurement of N-terminal pro-brain natriuretic peptide plasma levels in asymptomatic patients with aortic stenosis to predict symptomatic deterioration
    Ivor L Gerber
    Department of Cardiology, Auckland City Hospital, Auckland New Zealand
    Am J Cardiol 95:898-901. 2005
    ..Measurement of NT-pro-BNP in addition to clinical assessment and echocardiography may allow more reliable follow-up and timing of valve replacement for aortic stenosis...
  26. ncbi request reprint Frequency of recurrent ST-elevation myocardial infarction after fibrinolytic therapy in a different territory as a manifestation of multiple unstable coronary arterial plaques
    John J Edmond
    Cardiology Department, Green Lane Hospital, Auckland, New Zealand
    Am J Cardiol 97:947-51. 2006
    ....
  27. ncbi request reprint Variation in blood levels of inflammatory markers related and unrelated to smoking cessation in women
    Christopher J K Hammett
    Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Prev Cardiol 10:68-75. 2007
    ..1; interquartile range -0.2, 0.9 mg/L), intercellular adhesion molecule 1 (+17+/-75 ng/mL), or CD40 ligand (+0.4+/-2.1 ng/mL). Most of the individual variation in inflammatory marker levels was unrelated to changes in smoking habit...
  28. ncbi request reprint Coronary sinus and ascending aortic levels of aldosterone, angiotensin II, and B-type natriuretic peptide in patients with aortic stenosis and in patients with coronary heart disease
    Cara A Wasywich
    Cardiology Department, Green Lane Cardiovascular Service, Auckland City Hospital, Auckland, New Zealand
    Am J Cardiol 97:1068-72. 2006
    ....
  29. ncbi request reprint Increased plasma natriuretic peptide levels reflect symptom onset in aortic stenosis
    Ivor L Gerber
    Cardiology Department, Green Lane Hospital, Auckland, New Zealand
    Circulation 107:1884-90. 2003
    ..This study assessed the associations between natriuretic peptide levels, disease severity, and cardiac symptoms in aortic stenosis...
  30. ncbi request reprint Effect of aortic valve replacement on c-reactive protein in nonrheumatic aortic stenosis
    Ivor L Gerber
    Cardiology Department, Green Lane Hospital, Auckland, New Zealand
    Am J Cardiol 92:1129-32. 2003
    ..C-reactive protein decreased from before to 6 months after aortic valve replacement for aortic stenosis. These observations suggest that aortic stenosis is an inflammatory disease...
  31. ncbi request reprint Percutaneous coronary intervention with bivalirudin anticoagulation, immediate sheath removal, and early ambulation: a feasibility study with implications for day-stay procedures
    John A Ormiston
    Mercy Angiography, Auckland, New Zealand
    Catheter Cardiovasc Interv 55:289-93. 2002
    ....
  32. ncbi request reprint Prognostic differences between different types of bundle branch block during the early phase of acute myocardial infarction: insights from the Hirulog and Early Reperfusion or Occlusion (HERO)-2 trial
    Cheuk Kit Wong
    Cardiovascular Research Unit, Green Lane Cardiovascular Service, Auckland City Hospital, Private Bag 92024, Auckland 1030, New Zealand
    Eur Heart J 27:21-8. 2006
    ..Bundle branch block (BBB) early during acute myocardial infarction (AMI) is often considered high risk for mortality. Little is known about how different BBB types influence prognosis...
  33. doi request reprint MRI phase contrast velocity and flow errors in turbulent stenotic jets
    Kieran R O'Brien
    Bioengineering Institute, University of Auckland, Auckland, New Zealand
    J Magn Reson Imaging 28:210-8. 2008
    ..To clarify the use of MRI phase contrast (PC), as an alternative to Doppler echocardiography, when measuring high-velocity turbulent jets associated with stenotic valvular disease...
  34. ncbi request reprint Increased B-type natriuretic peptide is associated with an abnormal blood pressure response to exercise in asymptomatic aortic stenosis
    Niels C Van Pelt
    Green Lane Cardiovascular Service, Auckland City Hospital, New Zealand
    Int J Cardiol 127:313-20. 2008
    ..This study examines the relationship between the response to treadmill exercise and plasma levels of BNP in AS...
  35. ncbi request reprint Increased myocardial ischemia after food is not explained by endothelial dysfunction
    Colin Edwards
    Cardiovascular Research Unit, Green Lane Hospital, Auckland, New Zealand
    Am Heart J 144:E8. 2002
    ..The aim of this study was to determine whether greater myocardial ischemia after either a low-fat or a high-fat meal is associated with an increase in brachial artery endothelial dysfunction...
  36. doi request reprint Medical treatment of asymptomatic chronic aortic regurgitation
    Aaron Lin
    Green Lane Cardiovascular Unit, Auckland City Hospital, Park Road, Auckland, New Zealand
    Expert Rev Cardiovasc Ther 9:1249-54. 2011
    ..For these reasons, decisions on whether vasodilators are indicated in individual patients must currently be based on clinical judgment alone...
  37. ncbi request reprint Relationship between lipid levels and clinical outcomes in the Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) Trial: to what extent is the reduction in coronary events with pravastatin explained by on-study lipid levels?
    R John Simes
    National Health and Medical Research Council Clinical Trials Centre, University of Sydney, Australia
    Circulation 105:1162-9. 2002
    ..0 to 7.0 mmol/L at baseline. Secondary objectives included assessment of CHD event reduction according to lipid levels...
  38. ncbi request reprint Broader indications for B-type natriuretic peptide testing in coronary artery disease
    Ralph A H Stewart
    Eur Heart J 26:207-9. 2005
  39. ncbi request reprint Risk stratification of patients with acute anterior myocardial infarction and right bundle-branch block: importance of QRS duration and early ST-segment resolution after fibrinolytic therapy
    Cheuk Kit Wong
    Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    Circulation 114:783-9. 2006
    ..Patients with an acute anterior ST-segment elevation myocardial infarction and right bundle-branch block (RBBB) have a high mortality risk, which may be stratified by early ECG changes...