Christine E Thomson
Affiliation: Massey University
Country: New Zealand
- Murine spinal cord explants: a model for evaluating axonal growth and myelination in vitroChristine E Thomson
Applied Neurobiology Group, Institute of Comparative Medicine, Division of Cell Sciences, University of Glasgow Veterinary School, Glasgow, Scotland, UK
J Neurosci Res 84:1703-15. 2006..This tissue culture model should facilitate the study of factors involved in promoting outgrowth of CNS axons and their myelination. As such it is relevant to studies on myelination and spinal cord repair...
- Myelinated, synapsing cultures of murine spinal cord--validation as an in vitro model of the central nervous systemC E Thomson
Comparative Anatomy and Physiology, Institute of Veterinary, Biomedical and Animal Sciences, Massey University, Palmerston North, New Zealand
Eur J Neurosci 28:1518-35. 2008..The method is technically quick, easy and reliable, and should have wide application to CNS research...
- Distribution of mitochondria along small-diameter myelinated central nervous system axonsJulia M Edgar
Applied Neurobiology Group, Institute of Comparative Medicine, University of Glasgow, Bearsden, Glasgow, Scotland
J Neurosci Res 86:2250-7. 2008..We find that mitochondrial numbers do not change along the length of a myelinated small-diameter fiber, and, in contrast to the peripheral nervous system, there is no tendency for mitochondrial numbers to increase at the node...
- Processing of PLP in a model of Pelizaeus-Merzbacher disease/SPG2 due to the rumpshaker mutationMark McLaughlin
Applied Neurobiology Group, Institute of Comparative Medicine, University of Glasgow, Bearsden Glasgow G61 1QH, Scotland
Glia 53:715-22. 2006..Rumpshaker oligodendrocytes also have a reduced level of other myelin proteins, such as MBP, although the mechanisms are not yet defined but are likely to operate at a translational or post-translational level...