Evelyn Sattlegger

Summary

Affiliation: Massey University
Country: New Zealand

Publications

  1. pmc Gcn1 and actin binding to Yih1: implications for activation of the eIF2 kinase GCN2
    Evelyn Sattlegger
    Institute of Natural Sciences, Massey University, Auckland 0745, New Zealand
    J Biol Chem 286:10341-55. 2011
  2. pmc Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation
    Jyothsna Visweswaraiah
    Institute of Natural Sciences, Massey University, Auckland 0745, New Zealand
    J Biol Chem 287:37757-68. 2012
  3. doi request reprint Evidence that Yih1 resides in a complex with ribosomes
    Tracey Waller
    Institute of Natural Sciences, Massey University, Auckland, New Zealand
    FEBS J 279:1761-76. 2012
  4. pmc Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity
    Jyothsna Visweswaraiah
    Institute of Natural Sciences, Massey University, Auckland 0745, New Zealand
    J Biol Chem 286:36568-79. 2011

Collaborators

Detail Information

Publications4

  1. pmc Gcn1 and actin binding to Yih1: implications for activation of the eIF2 kinase GCN2
    Evelyn Sattlegger
    Institute of Natural Sciences, Massey University, Auckland 0745, New Zealand
    J Biol Chem 286:10341-55. 2011
    ..Our results support a role for Yih1 in a cross-talk between the cytoskeleton and translation...
  2. pmc Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation
    Jyothsna Visweswaraiah
    Institute of Natural Sciences, Massey University, Auckland 0745, New Zealand
    J Biol Chem 287:37757-68. 2012
    ..Together, this suggests that eEF3 blocks Gcn1 regulatory function on the ribosome. We propose that the Gcn1-Gcn2 complex only functions on ribosomes with A-site-bound uncharged tRNA, because eEF3 does not occupy these stalled complexes...
  3. doi request reprint Evidence that Yih1 resides in a complex with ribosomes
    Tracey Waller
    Institute of Natural Sciences, Massey University, Auckland, New Zealand
    FEBS J 279:1761-76. 2012
    ..Close physical proximity of Yih1 to the Gcn1-Gcn2-ribosome complex would allow cells to quickly inhibit Gcn2 whenever or wherever necessary...
  4. pmc Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity
    Jyothsna Visweswaraiah
    Institute of Natural Sciences, Massey University, Auckland 0745, New Zealand
    J Biol Chem 286:36568-79. 2011
    ..These findings implicate eEF1A in the intricate regulation of Gcn2 and amino acid homeostasis...