Research Topics
| M C KrugerSummaryAffiliation: Massey University Country: New Zealand Publications
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Detail Information
Publications
Bone health comparison in seven Asian countries using calcaneal ultrasoundMarlena C Kruger
Institute of Food, Nutrition and Human Health, Massey University, Private Bag 11222, Palmerston North 4442, Palmerston North, New Zealand
BMC Musculoskelet Disord 14:81. 2013..The purpose of this study was to assess bone health in seven Asian countries using heel ultrasound...
High-calcium, vitamin D fortified milk is effective in improving bone turnover markers and vitamin D status in healthy postmenopausal Chinese womenM C Kruger
Institute of Food, Nutrition and Human Health, Massey University, Palmerston North, New Zealand
Eur J Clin Nutr 66:856-61. 2012..The purpose of the study was to evaluate the impact of a high-calcium vitamin D fortified milk (HCM) intervention on parathyroid hormone (PTH) levels, vitamin D status and markers of bone turnover in postmenopausal Chinese women...- Urbanization of black South African women may increase risk of low bone mass due to low vitamin D status, low calcium intake, and high bone turnoverMarlena C Kruger
Institute of Food, Nutrition and Human Health, Massey University, Palmerston North, New Zealand
Nutr Res 31:748-58. 2011..Further research is required to assess bone health and fracture risk in black African women... - Study protocol--metabolic syndrome, vitamin D and bone status in South Asian women living in Auckland, New Zealand: a randomised, placebo-controlled, double-blind vitamin D interventionPamela R von Hurst
Institute of Food, Nutrition and Human Health, Massey University, Palmerston North, New Zealand
BMC Public Health 8:267. 2008..There is also some limited evidence that vitamin D influences insulin resistance, and thus the early stages of the development of type 2 diabetes... - Long-chain polyunsaturated fatty acids: selected mechanisms of action on boneM C Kruger
Institute of Food, Nutrition and Human Health, Massey University, Palmerston North, New Zealand
Prog Lipid Res 49:438-49. 2010..This review addresses selected cellular mechanisms that may explain the beneficial effects of the LCPUFAs on bone... - The effect of a fortified milk drink on vitamin D status and bone turnover in post-menopausal women from South East AsiaMarlena C Kruger
IFNHH, Massey University, Palmerston North, New Zealand
Bone 46:759-67. 2010..Thus, the HCM intervention was able to significantly improve vitamin D status, lower PTH levels and reduce bone turnover in two groups of South East Asian women... 
The effect of fructooligosaccharides with various degrees of polymerization on calcium bioavailability in the growing ratMarlena C Kruger
Institute of Food, Nutrition and Human Health, Massey University, Palmerston North, New Zealand
Exp Biol Med (Maywood) 228:683-8. 2003..In our model, inulin (DP>23) had the most significant effect on calcium bioavailability...- Effect of calcium fortified milk supplementation with or without vitamin K on biochemical markers of bone turnover in premenopausal womenMarlena C Kruger
Institute of Food, Nutrition and Human Health, Massey University, Palmerston North, New Zealand
Nutrition 22:1120-8. 2006..We compared the effect of supplementation with a fortified skimmed milk product (high calcium skim milk) with or without added phylloquinone (vitamin K(1)) on markers of bone formation and resorption in premenopausal women... - The effect of whey acidic protein fractions on bone loss in the ovariectomised ratMarlena C Kruger
Institute of Food, Nutrition and Human Health, Massey University, Private Bag 11222, Palmerston North, New Zealand
Br J Nutr 94:244-52. 2005..The femurs of AF-supplemented rats all showed an increase in organic matter. This is the first report of an acidic whey protein fraction isolated from milk whey that may support the recovery of bone loss in vivo... - Is docosahexaenoic acid more effective than eicosapentaenoic acid for increasing calcium bioavailability?Marlena C Kruger
Institute of Food, Nutrition and Human Health, Massey University, Palmerston North, New Zealand
Prostaglandins Leukot Essent Fatty Acids 73:327-34. 2005..DHA increased accretion of calcium in bone significantly more so than eicosapentaenoic acid (EPA) (20:5n-3)... - Vitamin D supplementation suppresses age-induced bone turnover in older women who are vitamin D deficientP R von Hurst
Institute of Food, Nutrition and Human Health, Massey University, Private Bag 102 904, North Shore Mail Centre, Auckland, New Zealand
J Steroid Biochem Mol Biol 121:293-6. 2010..We conclude that correcting vitamin D deficiency in older women suppresses the age-induced increase in bone turnover and reduces bone resorption which would normally be exacerbated in conditions of low serum 25(OH)D... - Detrimental effect of eicosapentaenoic acid supplementation on bone following ovariectomy in ratsRaewyn C Poulsen
Institute of Food Nutrition and Human Health, Massey University, Palmerston North, New Zealand
Prostaglandins Leukot Essent Fatty Acids 75:419-27. 2006..0006 and 0.02, respectively). In conclusion, high-dose EPA supplementation exacerbated the effects of ovariectomy on BMD... - Docosahexaenoic acid and 17 beta-estradiol co-treatment is more effective than 17 beta-estradiol alone in maintaining bone post-ovariectomyRaewyn C Poulsen
Institute of Food, Nutrition and Human Health, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand
Exp Biol Med (Maywood) 233:592-602. 2008.... - Specific effects of gamma-linolenic, eicosapentaenoic, and docosahexaenoic ethyl esters on bone post-ovariectomy in ratsR C Poulsen
Institute of Food Nutrition and Human Health, Massey University, Palmerston North, New Zealand 4442
Calcif Tissue Int 81:459-71. 2007..In conclusion, DHA ameliorated OVX-induced bone mineral loss. GLA exacerbated post-OVX bone mineral loss, possibly as a result of PTH-induced bone catabolism... - Anthocyanin absorption and antioxidant status in pigsMichaela C Walton
Institute of Food, Nutrition, and Human Health, Massey University, Private Bag 11 222, Palmerston North, New Zealand
J Agric Food Chem 54:7940-6. 2006..Our results also suggest that the increase in antioxidant capacity is not due to dietary anthocyanins but may be due to metabolites that result from anthocyanin consumption... - Long chain polyunsaturated fatty acids alter membrane-bound RANK-L expression and osteoprotegerin secretion by MC3T3-E1 osteoblast-like cellsRaewyn C Poulsen
Institute of Food, Nutrition and Human Health, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand
Prostaglandins Other Lipid Mediat 85:42-8. 2008..EPA and DHA have no effect on membrane-bound RANKL expression in cells cultured under standard conditions however both EPA and DHA inhibit the PGE2-induced increase in RANKL expression in MC3T3-E1/4 cells... - Long-chain polyunsaturated fatty acids and the regulation of bone metabolismRaewyn C Poulsen
Institute of Food, Nutrition and Human Health, Private Bag 11 222, Palmerston North, New Zealand
Exp Biol Med (Maywood) 232:1275-88. 2007..This review summarizes findings from both in vivo and in vitro studies and outlines the effects of LCPUFAs and their metabolites on calcium balance, osteoblastogenesis, osteoclastogenesis, and osteoblast and osteoclast function... - Identification of inflammatory and proresolving lipid mediators in bone marrow and their lipidomic profiles with ovariectomy and omega-3 intakeRaewyn C Poulsen
Institute of Food Nutrition and Human Health, Massey University, Palmerston North, New Zealand
Am J Hematol 83:437-45. 2008.... - The effect of aspirin and smoking on urinary excretion profiles of lactulose and mannitol in young women: toward a dynamic, aspirin augmented, test of gut mucosal permeabilityI R Sequeira
Institute of Food, Nutrition and Human Health, Massey University, Palmerston North, New Zealand
Neurogastroenterol Motil 24:e401-11. 2012..We explored the temporal dynamics of the lactulose mannitol test and the influence of a single dose of aspirin... - Changes in mineralization and biomechanics of tibial metaphyses in splinted ratsR G Lentle
Institute of Food Nutrition and Human Health, Massey Univ, Private Bag 11222, Palmerston North, New Zealand
J Appl Physiol 99:173-80. 2005..Thus osteoporotic changes consequent on immobilization include both local effects on mineralization and general effects on growth, which may separately influence the elastic properties of bone... - Ileal and faecal digestibility of daidzein and genistein and plasma bioavailability of these isoflavones and their bioactive metabolites in the ovariectomised ratRaewyn C Poulsen
Institute of Food Nutrition and Human Health, Massey University, Palmerston North, New Zealand
Mol Nutr Food Res 53:S27-35. 2009..Further studies are required to determine whether 4-ethylphenol is a major metabolite of genistein in humans and the extent of biotransformation of daidzein to equol in the small intestine in humans... - Soy phytoestrogens: impact on postmenopausal bone loss and mechanisms of actionRaewyn C Poulsen
Institute of Food Nutrition and Human Health, Massey University, Palmerston North, New Zealand
Nutr Rev 66:359-74. 2008.... - Polyunsaturated fatty acids and bone massHope A Weiler
Am J Clin Nutr 80:1085-6; author reply 1086-7. 2004 - Omega-3 fatty acids modulate ATPases involved in duodenal Ca absorptionMarianne Haag
Department of Physiology, University of Pretoria, PO Box 2034, Pretoria 0001, South Africa
Prostaglandins Leukot Essent Fatty Acids 68:423-9. 2003..01), this effect was partially reversed by 100 microM indomethacin, a cyclo-oxygenase blocker. Omega-3 fatty acids are thus involved in multiple signalling effects that effect ATPases in BLM... - Osteoprotegerin-receptor activator of nuclear factor-kappaB ligand ratio: a new approach to osteoporosis treatment?Magdalena Coetzee
Department of Physiology, University of Pretoria, Pretoria, Republic of South Africa
South Med J 97:506-11. 2004..The relative ratio of OPG and RANK ligand in the bone marrow microenvironment may determine the number of active osteoclasts, bone resorption rate, and bone mass. OPG is currently under investigation for osteoporosis treatment... - Effects of arachidonic acid, docosahexaenoic acid, prostaglandin E(2) and parathyroid hormone on osteoprotegerin and RANKL secretion by MC3T3-E1 osteoblast-like cellsMagdalena Coetzee
Department of Physiology, University of Pretoria, PO Box 2034, Pretoria 0001, South Africa
J Nutr Biochem 18:54-63. 2007..This study demonstrates that AA and PTH reduce the OPG/RANKL ratio and may increase osteoclastogenesis. DHA, however, had no significant effect on OPG or RANKL in this model...