- Allele-specific differences in ryanodine receptor 1 mRNA expression levels may contribute to phenotypic variability in malignant hyperthermiaHilbert Grievink
Institute of Molecular Biosciences, Massey University, Private Bag 11 222, Palmerston North, New Zealand
Orphanet J Rare Dis 5:10. 2010..The primary locus of MH (MHS1 locus) in humans is linked to chromosome 19q13.1, the position of the gene encoding the ryanodine receptor skeletal muscle calcium release channel (RyR1)...
- Identification of ryanodine receptor 1 single-nucleotide polymorphisms by high-resolution melting using the LightCycler 480 SystemHilbert Grievink
Institute of Molecular Biosciences, Massey University, Palmerston North 11 222, New Zealand
Anal Biochem 374:396-404. 2008..Thus, the LightCycler 480 System provides a novel, integrated, real-time PCR/HRM platform that allows high throughput, inexpensive SNP detection, and genotyping based on high-resolution amplicon melting...