David L Jardine

Summary

Country: New Zealand

Publications

  1. ncbi request reprint Decrease in cardiac output and muscle sympathetic activity during vasovagal syncope
    D L Jardine
    Department of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Am J Physiol Heart Circ Physiol 282:H1804-9. 2002
  2. ncbi request reprint Hodgkin's disease following methotrexate therapy for rheumatoid arthritis
    David L Jardine
    Department of General Medicine, Christchurch Hospital, Christchurch
    N Z Med J 115:293-4. 2002
  3. doi request reprint Vasovagal syncope: new physiologic insights
    D L Jardine
    Department of General Medicine, Christchurch Hospital, Private Bag, Riccarton Avenue, Christchurch, New Zealand
    Cardiol Clin 31:75-87. 2013
  4. doi request reprint Sympatho-vagal responses in patients with sleep and typical vasovagal syncope
    David L Jardine
    Department of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Clin Sci (Lond) 117:345-53. 2009
  5. ncbi request reprint Tilt-test diagnosis of hypotensive transient ischaemic attacks
    D L Jardine
    Department of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Intern Med J 37:498-501. 2007
  6. ncbi request reprint Cardiac sympathetic nerve activity and ventricular fibrillation during acute myocardial infarction in a conscious sheep model
    D L Jardine
    Department of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Am J Physiol Heart Circ Physiol 293:H433-9. 2007
  7. ncbi request reprint Fainting in your sleep?
    David L Jardine
    Dept of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Clin Auton Res 16:76-8. 2006
  8. pmc Increased cardiac sympathetic nerve activity following acute myocardial infarction in a sheep model
    D L Jardine
    Department of Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand
    J Physiol 565:325-33. 2005
  9. ncbi request reprint A bad dose of the 'flu
    D L Jardine
    Department of General Medicine, Christchurch Hospital, Private Bag 4710, Christchurch, New Zealand
    Lancet 362:1198. 2003
  10. ncbi request reprint Continual recordings of cardiac sympathetic nerve activity in conscious sheep
    David L Jardine
    Department of General Medicine, PO Box 4710, Christchurch Hospital, School of Medicine, Christchurch, New Zealand
    Am J Physiol Heart Circ Physiol 282:H93-9. 2002

Detail Information

Publications21

  1. ncbi request reprint Decrease in cardiac output and muscle sympathetic activity during vasovagal syncope
    D L Jardine
    Department of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Am J Physiol Heart Circ Physiol 282:H1804-9. 2002
    ..56, P = 0.001) and MSNA (R = 0.58, P = 0.001) than CO (R = 0.32, P = 0.001). In vasovagal reactions, a progressive decline in CO may contribute to hypotension some minutes before syncope occurs...
  2. ncbi request reprint Hodgkin's disease following methotrexate therapy for rheumatoid arthritis
    David L Jardine
    Department of General Medicine, Christchurch Hospital, Christchurch
    N Z Med J 115:293-4. 2002
  3. doi request reprint Vasovagal syncope: new physiologic insights
    D L Jardine
    Department of General Medicine, Christchurch Hospital, Private Bag, Riccarton Avenue, Christchurch, New Zealand
    Cardiol Clin 31:75-87. 2013
    ..The aim is to dissect out the different mechanisms for hypotension, then integrate current knowledge and clarify the sequence...
  4. doi request reprint Sympatho-vagal responses in patients with sleep and typical vasovagal syncope
    David L Jardine
    Department of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Clin Sci (Lond) 117:345-53. 2009
    ..This is consistent with sleep syncope being a subform of vasovagal syncope. Attenuation of sympathetic responses to non-baroreflex pathways may be important in the mechanism of vasovagal syncope...
  5. ncbi request reprint Tilt-test diagnosis of hypotensive transient ischaemic attacks
    D L Jardine
    Department of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Intern Med J 37:498-501. 2007
    ..During tilt, postural hypotension was found in five patients and in three patients transient ischaemic attacks were reproduced. Postural hypotension is probably a rare cause of transient ischaemic attacks, but may be underrecognized...
  6. ncbi request reprint Cardiac sympathetic nerve activity and ventricular fibrillation during acute myocardial infarction in a conscious sheep model
    D L Jardine
    Department of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Am J Physiol Heart Circ Physiol 293:H433-9. 2007
    ..14). CSNA slopes were -1.8 +/- 0.3 and -2.3 +/- 0.2%/mmHg (t(18) = -1.4, P = 0.2). An early increase in CSNA burst size indexes (before 60 min post-MI), mediated by an excitatory sympathetic reflex, is important in the genesis of VF/VT...
  7. ncbi request reprint Fainting in your sleep?
    David L Jardine
    Dept of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Clin Auton Res 16:76-8. 2006
  8. pmc Increased cardiac sympathetic nerve activity following acute myocardial infarction in a sheep model
    D L Jardine
    Department of Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand
    J Physiol 565:325-33. 2005
    ..The duration of this response may be longer because the recording fields decrease with time. This result is consistent with a sustained cardiac excitatory sympathetic reflex...
  9. ncbi request reprint A bad dose of the 'flu
    D L Jardine
    Department of General Medicine, Christchurch Hospital, Private Bag 4710, Christchurch, New Zealand
    Lancet 362:1198. 2003
  10. ncbi request reprint Continual recordings of cardiac sympathetic nerve activity in conscious sheep
    David L Jardine
    Department of General Medicine, PO Box 4710, Christchurch Hospital, School of Medicine, Christchurch, New Zealand
    Am J Physiol Heart Circ Physiol 282:H93-9. 2002
    ..In conclusion, CSNA that can be continually recorded in conscious sheep decreases during the first week postsurgery and, thereafter, stabilizes. This model should provide valuable insights in future investigations of cardiac disease...
  11. ncbi request reprint Urocortin 1 exhibits potent inhibition of cardiac sympathetic nerve activity in conscious sheep
    Christopher J Charles
    Christchurch Cardioendocrine Research Group, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand
    J Hypertens 26:53-60. 2008
    ..Urocortin 1 (Ucn1) and the sympathetic nervous system both participate in cardiac and circulatory regulation, but little is known about their possible interactions...
  12. doi request reprint Urocortin 3 inhibits cardiac sympathetic nerve activity in conscious sheep
    Christopher J Charles
    Christchurch Cardioendocrine Research Group, University of Otago, Christchurch, New Zealand
    J Cardiovasc Pharmacol 58:418-23. 2011
    ..This provides further support for a role for Ucn3 in pressure and volume homeostasis and suggests that further investigation of potential therapeutic applications for Ucn3 in cardiovascular disease is warranted...
  13. doi request reprint Urocortin 2 induces potent long-lasting inhibition of cardiac sympathetic drive despite baroreflex activation in conscious sheep
    Christopher J Charles
    Christchurch Cardioendocrine Research Group, University of Otago, Christchurch, Christchurch 8140, New Zealand
    J Endocrinol 204:181-9. 2010
    ..These findings suggest an important role for UCN2 in cardiovascular homeostasis and warrant further investigation for potential therapeutic applications in acute myocardial injury and heart disease...
  14. ncbi request reprint Adrenomedullin increases cardiac sympathetic nerve activity in normal conscious sheep
    C J Charles
    Christchurch Cardioendocrine Research Group, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    J Endocrinol 187:275-81. 2005
    ..In conclusion, we have demonstrated that AM is associated with a greater increase in CSNA and heart rate for a given change in arterial pressure than seen with the classic balanced vasodilator NP...
  15. ncbi request reprint A Comparative Study of Blood Pressure Control with Short In-Center versus Long Home Hemodialysis
    D O McGregor
    Department of Nephrology, Christchurch Hospital, Christchurch, New Zealand
    Blood Purif 19:293-300. 2001
    ..These findings suggest that additional factors to ECF volume may contribute to the superior BP control produced by long-slow HD...
  16. doi request reprint Vagolysis
    C D Hutchinson
    Canterbury District Health Board, Christchurch, New Zealand
    Age Ageing 37:602-4. 2008
    ....
  17. ncbi request reprint Baroreceptor denervation presenting as part of a vagal mononeuropathy
    D L Jardine
    Cardiology Department, Christchurch Hospital, New Zealand
    Clin Auton Res 10:69-75. 2000
    ..In addition, parasympathetic control of heart rate was absent and consistent with a bilateral, nonselective lesion in the proximal vagus...
  18. pmc Influence of ABCB1 (P-glycoprotein) haplotypes on nortriptyline pharmacokinetics and nortriptyline-induced postural hypotension in healthy volunteers
    Berit Packert Jensen
    Department of Medicine, University of Otago, Christchurch, New Zealand
    Br J Clin Pharmacol 73:619-28. 2012
    ..This finding needs to be replicated in independent studies before recommendations regarding pharmacogenetic testing can be made...
  19. ncbi request reprint Respiratory failure secondary to diabetic neuropathy affecting the phrenic nerve
    E W Tang
    Department of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Diabet Med 20:599-601. 2003
    ..The pathology of diabetic mononeuropathy is not well understood and we believe this to be the first histological report of a phrenic nerve biopsy in this condition...
  20. ncbi request reprint Variegate porphyria presenting with acute autonomic dysfunction, intussusception and renal infarction
    J C Griffith
    Dept of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Scand J Gastroenterol 39:500-3. 2004
    ..Increased sympathetic activity may also have caused intussusception and focal renal vasoconstriction, both of which may be underdiagnosed causes of abdominal pain in acute porphyria...
  21. ncbi request reprint Angry fat
    David L Jardine
    J Rheumatol 33:1030. 2006