I M Holdaway

Summary

Country: New Zealand

Publications

  1. doi request reprint Excess mortality in acromegaly
    I M Holdaway
    Department of Endocrinology, Greenlane Clinical Centre, Auckland City Hospital, Auckland, New Zealand
    Horm Res 68:166-72. 2007
  2. doi request reprint A meta-analysis of the effect of lowering serum levels of GH and IGF-I on mortality in acromegaly
    I M Holdaway
    Department of Endocrinology, Greenlane Clinical Centre and Auckland City Hospital, PO Box 92189, Auckland 1142, New Zealand
    Eur J Endocrinol 159:89-95. 2008
  3. ncbi request reprint Long-term treatment outcome in acromegaly
    I M Holdaway
    Department of Endocrinology, Auckland Hospital, Park Road, Auckland 1, New Zealand
    Growth Horm IGF Res 13:185-92. 2003
  4. ncbi request reprint Factors influencing mortality in acromegaly
    Ian M Holdaway
    Department of Endocrinology, Auckland Hospital, Auckland 1, New Zealand
    J Clin Endocrinol Metab 89:667-74. 2004
  5. ncbi request reprint Treatment of acromegaly
    Ian M Holdaway
    Department of Endocrinology, Auckland Hospital, Auckland, New Zealand
    Horm Res 62:79-92. 2004
  6. ncbi request reprint Serum insulin-like growth factor-I and insulin-like growth factor binding protein-3 following chemotherapy for advanced breast cancer
    Ian M Holdaway
    Departments of Endocrinology and Oncology, Auckland Hospital, Auckland, New Zealand
    ANZ J Surg 73:905-8. 2003
  7. ncbi request reprint Serum levels of insulin-like growth factor binding protein-3 in benign and malignant breast disease
    I M Holdaway
    Department of Endocrinology, School of Medicine, Auckland University, New Zealand
    Aust N Z J Surg 69:495-500. 1999
  8. ncbi request reprint The relationship of urinary and plasma androgens to steroid receptors and menopausal status in breast cancer patients and their influence on survival
    B H Mason
    Department of Endocrinology, School of Medicine, Auckland, New Zealand
    Breast Cancer Res Treat 32:203-12. 1994
  9. pmc Characteristics of the menstrual cycle at the time of surgery for breast cancer
    I M Holdaway
    Department of Endocrinology, University of Auckland School of Medicine, New Zealand
    Br J Cancer 75:413-6. 1997
  10. pmc Season of initial discovery of tumour as an independent variable predicting survival in breast cancer
    B H Mason
    Department of Surgery, Auckland Hospital, New Zealand
    Br J Cancer 61:137-41. 1990

Collaborators

  • I D Civil
  • G A Whalley
  • M J Bolland
  • W Bagg
  • Jencia Wong
  • Alistair W Stewart
  • Audrey H Schnell
  • Don R Love
  • Robert C Elston
  • Andre Daniels
  • Kathleen G Mountjoy
  • Marie White
  • Cam Kyle
  • B H Mason
  • R G Kay
  • S J Skinner
  • A W Stewart
  • L M Neave

Detail Information

Publications15

  1. doi request reprint Excess mortality in acromegaly
    I M Holdaway
    Department of Endocrinology, Greenlane Clinical Centre, Auckland City Hospital, Auckland, New Zealand
    Horm Res 68:166-72. 2007
    ..The range of standardised mortality rates in various studies ranges from 1.2 to 3.6...
  2. doi request reprint A meta-analysis of the effect of lowering serum levels of GH and IGF-I on mortality in acromegaly
    I M Holdaway
    Department of Endocrinology, Greenlane Clinical Centre and Auckland City Hospital, PO Box 92189, Auckland 1142, New Zealand
    Eur J Endocrinol 159:89-95. 2008
    ..A meta-analysis of mortality studies in acromegaly has thus been performed to assess the effect of lowering serum GH and IGF-I on survival...
  3. ncbi request reprint Long-term treatment outcome in acromegaly
    I M Holdaway
    Department of Endocrinology, Auckland Hospital, Park Road, Auckland 1, New Zealand
    Growth Horm IGF Res 13:185-92. 2003
    ..Available data suggest that achieving similar growth hormone levels after treatment also reduces the prevalence of chronic complications of the disorder, which is subsequently reflected in improved mortality...
  4. ncbi request reprint Factors influencing mortality in acromegaly
    Ian M Holdaway
    Department of Endocrinology, Auckland Hospital, Auckland 1, New Zealand
    J Clin Endocrinol Metab 89:667-74. 2004
    ..02), indicating that GH and IGF-I act equivalently as predictors of mortality. These findings indicate that reduction of GH to less than 1 microg/liter or normalization of serum IGF-I reduces mortality to expected levels...
  5. ncbi request reprint Treatment of acromegaly
    Ian M Holdaway
    Department of Endocrinology, Auckland Hospital, Auckland, New Zealand
    Horm Res 62:79-92. 2004
    ..A primary surgical approach, followed by medical therapy for those not in remission, remains the preferred option in most centres...
  6. ncbi request reprint Serum insulin-like growth factor-I and insulin-like growth factor binding protein-3 following chemotherapy for advanced breast cancer
    Ian M Holdaway
    Departments of Endocrinology and Oncology, Auckland Hospital, Auckland, New Zealand
    ANZ J Surg 73:905-8. 2003
    ..IGF-I and IGFBP-3 have therefore been measured in women with advanced breast cancer to determine if changes in serum levels predict the response to treatment by chemotherapy...
  7. ncbi request reprint Serum levels of insulin-like growth factor binding protein-3 in benign and malignant breast disease
    I M Holdaway
    Department of Endocrinology, School of Medicine, Auckland University, New Zealand
    Aust N Z J Surg 69:495-500. 1999
    ..The present study investigates whether this pattern also occurs in neoplastic breast disease...
  8. ncbi request reprint The relationship of urinary and plasma androgens to steroid receptors and menopausal status in breast cancer patients and their influence on survival
    B H Mason
    Department of Endocrinology, School of Medicine, Auckland, New Zealand
    Breast Cancer Res Treat 32:203-12. 1994
    ..Nonetheless, the identification of this subgroup of node negative breast cancer women with reduced survival may be important when considering node negative patients for adjuvant therapy...
  9. pmc Characteristics of the menstrual cycle at the time of surgery for breast cancer
    I M Holdaway
    Department of Endocrinology, University of Auckland School of Medicine, New Zealand
    Br J Cancer 75:413-6. 1997
    ..The timing of surgery in the cycle did not influence the hormonal data. The hormonal characteristics of the menstrual cycle thus appear to be normally preserved in women during the month in which breast cancer surgery is performed...
  10. pmc Season of initial discovery of tumour as an independent variable predicting survival in breast cancer
    B H Mason
    Department of Surgery, Auckland Hospital, New Zealand
    Br J Cancer 61:137-41. 1990
    ..This study suggests that the season of first detection of a breast cancer relates significantly to the later behaviour of the tumour, and may reflect seasonal changes in hormone dependent growth...
  11. pmc Seasonal changes in serum melatonin in women with previous breast cancer
    I M Holdaway
    Department of Endocrinology, Auckland Hospital, New Zealand
    Br J Cancer 64:149-53. 1991
    ....
  12. ncbi request reprint Effect of breast surgery on serum levels of insulin-like growth factors (IGF-I, IGF-II, and IGF binding protein-3) in women with benign and malignant breast lesions
    I M Holdaway
    Department of Endocrinology, School of Medicine, Auckland University, New Zealand
    Ann Surg Oncol 8:25-31. 2001
    ..001). The fall in IGF-II was significantly related to the size of the removed tumor. CONCLUSIONS: Breast cancer may directly influence the serum concentration of IGF-II, possibly by direct tumor production...
  13. ncbi request reprint Epidemiology of acromegaly
    I M Holdaway
    Department of Endocrinology, Auckland Hospital, New Zealand
    Pituitary 2:29-41. 1999
    ..Overall, however, the most important prognostic variable appears to be the serum GH concentration achieved by treatment, with an increasing consensus that this needs to be < 2.5 ug/L (5 mU/L) to achieve cure of the condition...
  14. ncbi request reprint Serum IGF-I levels are similar in Samoan, Māori and European populations despite differences in body composition
    W Bagg
    Department of Medicine, University of Auckland, E com House, 3 Ferncroft Street, Grafton, Auckland, New Zealand
    Growth Horm IGF Res 16:57-60. 2006
    ..To determine if serum IGF-I concentrations are similar in healthy adult subjects from the Samoan, Māori and European populations in New Zealand...
  15. ncbi request reprint Melanocortin-3 receptor gene variants in a Maori kindred with obesity and early onset type 2 diabetes
    Jencia Wong
    Department of Medicine, University of Auckland, Auckland, New Zealand
    Diabetes Res Clin Pract 58:61-71. 2002
    ....