Brian A Darlow

Summary

Affiliation: Christchurch School of Medicine and Health Sciences
Country: New Zealand

Publications

  1. pmc Vitamin C supplementation in very preterm infants: a randomised controlled trial
    B A Darlow
    Department of Paediatrics, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Arch Dis Child Fetal Neonatal Ed 90:F117-22. 2005
  2. ncbi request reprint Prenatal risk factors for severe retinopathy of prematurity among very preterm infants of the Australian and New Zealand Neonatal Network
    Brian A Darlow
    Department of Paediatrics, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Pediatrics 115:990-6. 2005
  3. pmc Improved outcomes for very low birthweight infants: evidence from New Zealand national population based data
    B A Darlow
    Department of Paediatrics, Christchurch School of Medicine, New Zealand
    Arch Dis Child Fetal Neonatal Ed 88:F23-8. 2003
  4. pmc Variation in rates of severe retinopathy of prematurity among neonatal intensive care units in the Australian and New Zealand Neonatal Network
    B A Darlow
    Department of Paediatrics, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Br J Ophthalmol 89:1592-6. 2005
  5. ncbi request reprint Regional differences in outcome for very low-birthweight infants: do they persist at 7-8 years of age?
    B A Darlow
    Department of Paediatrics, Christchurch School of Medicine, New Zealand
    J Paediatr Child Health 36:477-81. 2000
  6. ncbi request reprint Very low birthweight and asthma by age seven years in a national cohort
    B A Darlow
    Department of Paediatrics, Christchurch School of Medicine, Christchurch, New Zealand
    Pediatr Pulmonol 30:291-6. 2000
  7. ncbi request reprint Plasma amino-terminal pro C-type natriuretic Peptide in the neonate: relation to gestational age and postnatal linear growth
    Timothy C R Prickett
    Department of Medicine, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch Mail Centre, Christchurch 8140, New Zealand
    J Clin Endocrinol Metab 93:225-32. 2008
  8. ncbi request reprint Nuclear factor kappaB activation in pulmonary leukocytes from infants with hyaline membrane disease: associations with chorioamnionitis and Ureaplasma urealyticum colonization
    Fook Choe Cheah
    Free Radical Research Group, Department of Pathoplogy, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
    Pediatr Res 57:616-23. 2005
  9. doi request reprint Admissions of all gestations to a regional neonatal unit versus controls: 2-year outcome
    Brian A Darlow
    Department of Paediatrics, University of Otago, Christchurch, New Zealand
    J Paediatr Child Health 45:187-93. 2009
  10. doi request reprint Does observer bias contribute to variations in the rate of retinopathy of prematurity between centres?
    Brian A Darlow
    Department of Paediatrics, University of Otago, Christchurch, New Zealand
    Clin Experiment Ophthalmol 36:43-6. 2008

Collaborators

Detail Information

Publications39

  1. pmc Vitamin C supplementation in very preterm infants: a randomised controlled trial
    B A Darlow
    Department of Paediatrics, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Arch Dis Child Fetal Neonatal Ed 90:F117-22. 2005
    ..To determine whether regulating vitamin C (ascorbic acid: AA) intake to achieve higher or lower plasma concentrations was associated with improved clinical outcome...
  2. ncbi request reprint Prenatal risk factors for severe retinopathy of prematurity among very preterm infants of the Australian and New Zealand Neonatal Network
    Brian A Darlow
    Department of Paediatrics, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Pediatrics 115:990-6. 2005
    ..To identify prenatal and perinatal risk factors for clinically severe (stage 3 or 4) retinopathy of prematurity (ROP)...
  3. pmc Improved outcomes for very low birthweight infants: evidence from New Zealand national population based data
    B A Darlow
    Department of Paediatrics, Christchurch School of Medicine, New Zealand
    Arch Dis Child Fetal Neonatal Ed 88:F23-8. 2003
    ..To compare the survival and short term morbidity of all New Zealand very low birthweight (VLBW) infants born in two epochs, 1986 and 1998-1999...
  4. pmc Variation in rates of severe retinopathy of prematurity among neonatal intensive care units in the Australian and New Zealand Neonatal Network
    B A Darlow
    Department of Paediatrics, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Br J Ophthalmol 89:1592-6. 2005
    ..To analyse variations in rates of severe retinopathy of prematurity (ROP) among neonatal intensive care units (NICUs) in the Australian and New Zealand Neonatal Network (ANZNN), adjusting for sampling variability and for case mix...
  5. ncbi request reprint Regional differences in outcome for very low-birthweight infants: do they persist at 7-8 years of age?
    B A Darlow
    Department of Paediatrics, Christchurch School of Medicine, New Zealand
    J Paediatr Child Health 36:477-81. 2000
    ..To determine whether regional differences in early neonatal morbidity in a national cohort of very low-birthweight (VLBW) infants persisted at 7-8 years of age...
  6. ncbi request reprint Very low birthweight and asthma by age seven years in a national cohort
    B A Darlow
    Department of Paediatrics, Christchurch School of Medicine, Christchurch, New Zealand
    Pediatr Pulmonol 30:291-6. 2000
    ..There are suggestions that social factors contribute to both asthma risk and treatment...
  7. ncbi request reprint Plasma amino-terminal pro C-type natriuretic Peptide in the neonate: relation to gestational age and postnatal linear growth
    Timothy C R Prickett
    Department of Medicine, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch Mail Centre, Christchurch 8140, New Zealand
    J Clin Endocrinol Metab 93:225-32. 2008
    ..Whether correlations of NTproCNP with linear growth, as found in children and lambs, apply in neonates is unknown...
  8. ncbi request reprint Nuclear factor kappaB activation in pulmonary leukocytes from infants with hyaline membrane disease: associations with chorioamnionitis and Ureaplasma urealyticum colonization
    Fook Choe Cheah
    Free Radical Research Group, Department of Pathoplogy, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
    Pediatr Res 57:616-23. 2005
    ..Together, these observations suggest that NF-kappaB activation in pulmonary leukocytes may be involved in the lung inflammatory process in infants with HMD...
  9. doi request reprint Admissions of all gestations to a regional neonatal unit versus controls: 2-year outcome
    Brian A Darlow
    Department of Paediatrics, University of Otago, Christchurch, New Zealand
    J Paediatr Child Health 45:187-93. 2009
    ..To assess neurodevelopmental outcome at 2 years for neonatal intensive care unit (NICU) admissions compared with controls, and to trial a parent-reporting scheme...
  10. doi request reprint Does observer bias contribute to variations in the rate of retinopathy of prematurity between centres?
    Brian A Darlow
    Department of Paediatrics, University of Otago, Christchurch, New Zealand
    Clin Experiment Ophthalmol 36:43-6. 2008
    ..We aimed to indirectly assess the contribution from observer bias to between centre variability in the incidence of acute retinopathy of prematurity (ROP)...
  11. doi request reprint Urban-rural variation in childhood type 1 diabetes incidence in Canterbury, New Zealand, 1980-2004
    Laura J Miller
    Department of Geography, University of Canterbury, Christchurch, New Zealand
    Health Place 17:248-56. 2011
    ..Varying levels of immigration and or/commuting in different urban-rural settings could explain this finding. This study highlights the value of geographical investigations for aetiological hypothesis generation...
  12. doi request reprint Admission of all gestations to a regional neonatal unit versus controls: neonatal morbidity
    Brian A Darlow
    Department of Paediatrics, University of Otago, Christchurch, New Zealand
    J Paediatr Child Health 45:181-6. 2009
    ..Infants in both NICU and control cohorts were enrolled in a 2-year follow-up study...
  13. ncbi request reprint The effect of gestational age and labour on markers of lipid and protein oxidation in cord plasma
    Tessa J Mocatta
    Department of Pathology, Christchurch School of Medicine and Health Sciences, P O Box 4345, Christchurch, New Zealand
    Free Radic Res 38:185-91. 2004
    ..More information is needed on the source and fate of these and other biomarkers before drawing strong conclusions on how they reflect oxidative stress in this and other clinical situations...
  14. pmc Comparison of the Mycoplasma Duo test with PCR for detection of ureaplasma species in endotracheal aspirates from premature infants
    Fook Choe Cheah
    Department of Pathology, Christchurch School of Medicine and Health Sciences, University of Otago, P O Box 4345, Christchurch, New Zealand
    J Clin Microbiol 43:509-10. 2005
    ..in endotracheal aspirates from 60 premature neonates. The overall agreement between the two tests was 96%. The Mycoplasma Duo assay is a useful alternative to culture and PCR for detection of neonatal Ureaplasma infection...
  15. doi request reprint Acute inflammation in young children inhibits C-type natriuretic peptide
    Timothy C R Prickett
    Department of Medicine, University of Otago, Christchurch, New Zealand
    Pediatr Res 74:191-5. 2013
    ..Because severe inflammation in adults increases CNP, we studied CNP peptides and inflammatory markers in children with acute illness...
  16. ncbi request reprint Detection of apoptosis by caspase-3 activation in tracheal aspirate neutrophils from premature infants: relationship with NF-kappaB activation
    Fook Choe Cheah
    Department of Pathology, Christchurch School of Medicine and Health Sciences, P O Box 4345, Christchurch, New Zealand
    J Leukoc Biol 77:432-7. 2005
    ..In all but one tracheal aspirate sample, there was a mutually exclusive relationship between activated caspase-3 and NF-kappaB activation, which supports in vitro observations that NF-kappaB activation delays neutrophil apoptosis...
  17. ncbi request reprint Amino-terminal proCNP: a putative marker of cartilage activity in postnatal growth
    Timothy C R Prickett
    Department of Medicine, Christchurch School of Medicine and Health Sciences, Christchurch 8015, New Zealand
    Pediatr Res 58:334-40. 2005
    ..In summary, NT-proCNP levels in blood show a strong association with growth velocity and markers of bone formation and may well serve as a useful marker of growth plate activity in humans and other mammals...
  18. pmc Cognitive, educational, and behavioural outcomes at 7 to 8 years in a national very low birthweight cohort
    L J Horwood
    Christchurch Health and Development Study, Christchurch School of Medicine, New Zealand
    Arch Dis Child Fetal Neonatal Ed 79:F12-20. 1998
    ..To examine cognitive, behavioural, and educational outcomes in middle childhood among a birth cohort of very low birthweight children...
  19. pmc Infants in a neonatal intensive care unit: parental response
    J D Carter
    Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand
    Arch Dis Child Fetal Neonatal Ed 90:F109-13. 2005
    ..To compare the psychosocial functioning of the parents (mother and father) of infants admitted to a neonatal intensive care unit (NICU) with the parents of infants born at term and not admitted to the NICU...
  20. pmc Breast milk feeding and cognitive ability at 7-8 years
    L J Horwood
    Christchurch Health and Development Study and Department of Paediatrics, Christchurch School of Medicine, Christchurch, New Zealand
    Arch Dis Child Fetal Neonatal Ed 84:F23-7. 2001
    ..To examine the association between duration of breast milk feeding and cognitive ability at 7-8 years in a birth cohort of very low birthweight infants...
  21. ncbi request reprint Vitamin C is reduced in human milk after storage
    I H Buss
    Department of Pathology, University of Otago, Christchurch School of Medicine, New Zealand
    Acta Paediatr 90:813-5. 2001
    ..After 2 mo of freezing, the average decrease was two-thirds (7-100%)...
  22. doi request reprint Setting up and improving retinopathy of prematurity programs: interaction of neonatology, nursing, and ophthalmology
    Brian A Darlow
    Department of Paediatrics, University of Otago Christchurch, PO Box 4345, Christchurch 8140, New Zealand
    Clin Perinatol 40:215-27. 2013
    ..ROP programs will have different content and emphasis according to whether the setting is in an economically advanced or developing country...
  23. doi request reprint Psychosocial outcomes of young adults born very low birth weight
    Brian A Darlow
    FRACP, Department of Pediatrics, University of Otago Christchurch, PO Box 4345, Christchurch 8140, New Zealand
    Pediatrics 132:e1521-8. 2013
    ..The impact of neurodevelopmental disability at age 7 to 8 years on young adult outcomes was examined...
  24. ncbi request reprint Are gentamicin and/or vancomycin associated with ototoxicity in the neonate? A retrospective audit
    Jane W A Vella-Brincat
    Department of Clinical Pharmacology, Christchurch Hospital, Christchurch, New Zealand
    Neonatology 100:186-93. 2011
    ..Aminoglycoside-induced ototoxicity has been reported in neonates but its incidence is poorly defined, whereas vancomycin-induced ototoxicity has not been reported in neonates...
  25. doi request reprint Is population mixing associated with childhood type 1 diabetes in Canterbury, New Zealand?
    Laura J Miller
    University of Canterbury, Christchurch, New Zealand
    Soc Sci Med 68:625-30. 2009
    ..The findings suggest that large increases in population mixing, over short time periods, could act as a trigger for type 1 diabetes development in children...
  26. ncbi request reprint Problems associated with collecting breath condensate for the measurement of exhaled hydrogen peroxide from neonates on respiratory support
    Fook Choe Cheah
    Free Radical Research Group, Department of Pathology, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
    Biol Neonate 84:338-41. 2003
    ....
  27. ncbi request reprint 3-Chlorotyrosine as a marker of protein damage by myeloperoxidase in tracheal aspirates from preterm infants: association with adverse respiratory outcome
    I Hendrikje Buss
    Department of Pathology, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand
    Pediatr Res 53:455-62. 2003
    ..The higher 3-chlorotyrosine levels in infants who develop chronic lung disease suggest that neutrophil oxidants contribute to the pathology of this disease...
  28. ncbi request reprint Are we there yet? Bevacizumab therapy for retinopathy of prematurity
    Brian A Darlow
    Department of Paediatrics, Christchurch School of Medicine and Health Sciences, University of Otago Christchurch, PO Box 4345, Christchurch 8140, New Zealand
    Arch Dis Child Fetal Neonatal Ed 98:F170-4. 2013
    ....
  29. doi request reprint New Zealand surveillance of neonatal vitamin K deficiency bleeding (VKDB): 1998-2008
    Brian A Darlow
    Department of Paediatrics, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
    J Paediatr Child Health 47:460-4. 2011
    ..To undertake surveillance of vitamin K deficiency bleeding (VKDB) from 1998, through the transition to a new single licensed vitamin K preparation in 2001, to 2008...
  30. ncbi request reprint Infants admitted to a neonatal intensive care unit: parental psychological status at 9 months
    Janet D Carter
    Department of Psychology, University of Canterbury, Christchurch, New Zealand
    Acta Paediatr 96:1286-9. 2007
    ..The psychological status of the parent groups is compared and factors associated with status change are examined...
  31. ncbi request reprint Lipid peroxide and hydrogen peroxide formation in parenteral nutrition solutions containing multivitamins
    K M Silvers
    Department of Pathology, Christchurch School of Medicine, New Zealand
    JPEN J Parenter Enteral Nutr 25:14-7. 2001
    ..However, prevention of ascorbate loss and hydrogen peroxide formation in any multivitamin solution requires protection of the delivery system from light...
  32. ncbi request reprint Limiting light-induced lipid peroxidation and vitamin loss in infant parenteral nutrition by adding multivitamin preparations to Intralipid
    K M Silvers
    Free Radical Research Group, Department of Pathology, Christchurch School of Medicine, New Zealand
    Acta Paediatr 90:242-9. 2001
    ..This procedure should be considered for routine use as well as with phototherapy...
  33. ncbi request reprint Seasonality of birth and onset of clinical disease in children and adolescents (0-19 years) with type 1 diabetes mellitus in Canterbury, New Zealand
    Jinny A Willis
    Department of Paediatrics, Christchurch Hospital, New Zealand
    J Pediatr Endocrinol Metab 15:645-7. 2002
    ..To determine the seasonality of clinical disease onset and month of birth in type 1 diabetes mellitus (DM) in the southern hemisphere...
  34. ncbi request reprint Severe holocarboxylase synthetase deficiency with incomplete biotin responsiveness resulting in antenatal insult in samoan neonates
    Callum J Wilson
    National Metabolic Service, Starship Children s Hospital, the Neonatal Service, Kidz First Hospital, Auckland, New Zealand
    J Pediatr 147:115-8. 2005
    ..We describe 7 Polynesian babies with a unique severe form of holocarboxylase synthetase deficiency characterized by antenatal growth retardation, subependymal cysts, only partial response to biotin, and a poor outcome...
  35. ncbi request reprint Lowered electroencephalographic spectral edge frequency predicts the presence of cerebral white matter injury in premature infants
    Terrie E Inder
    Murdoch Children s Research Institute and Royal Women s and Royal Children s Hospital, Melbourne, Australia
    Pediatrics 111:27-33. 2003
    ..The critical measurement used, suggested largely by previous studies in animal models, was the spectral edge frequency (SEF), calculated here as the frequency below which 90% of the power in the EEG exists...
  36. ncbi request reprint The limits of perinatal viability: grappling with the "grey zone"
    Brian A Darlow
    Med J Aust 185:477-9. 2006
  37. ncbi request reprint Late antenatal carriage of group B Streptococcus by New Zealand women
    Keith Grimwood
    Department of Paediatrics and Child Health, Wellington School of Medicine and Health Sciences, New Zealand
    Aust N Z J Obstet Gynaecol 42:182-6. 2002
    ..To determine in New Zealand women the prevalence of group B Streptococcus (GBS) carriage late in pregnancy and to identify GBS colonisation risk factors, antibiotic susceptibility and serotype distribution...
  38. ncbi request reprint Incidence of type 1 diabetes mellitus diagnosed before age 20 years in Canterbury, New Zealand over the last 30 years
    Jinny A Willis
    Lipid and Diabetes Research Group, Christchurch Hospital, New Zealand
    J Pediatr Endocrinol Metab 15:637-43. 2002
    ..59 patients/100,000 per year, or an annual increase of 5% derived from regression of the natural logarithms of the incidence data. These observations are consistent with the increasing attack rates for type 1 DM reported worldwide...
  39. ncbi request reprint The relationship of CSF and plasma cytokine levels to cerebral white matter injury in the premature newborn
    Vanessa J Ellison
    Neonatal Medicine, Royal Women s Hospital, Melbourne, Victoria, Australia
    Pediatr Res 57:282-6. 2005
    ..Plasma cytokine concentrations may not reflect CSF cytokine levels or inflammatory events within the brain. Elevated CSF levels of cytokines in infants with white matter injury suggest an altered inflammatory balance...