S P Cairns

Summary

Affiliation: Auckland University of Technology
Country: New Zealand

Publications

  1. ncbi request reprint Evaluation of models used to study neuromuscular fatigue
    Simeon P Cairns
    Division of Sport and Recreation, Faculty of Health, Auckland University of Technology, Private Bag 92006, Auckland 1020, New Zealand
    Exerc Sport Sci Rev 33:9-16. 2005
  2. ncbi request reprint Lactic acid and exercise performance : culprit or friend?
    Simeon P Cairns
    Institute of Sport and Recreation Research New Zealand, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland, New Zealand
    Sports Med 36:279-91. 2006
  3. ncbi request reprint Changes of action potentials and force at lowered [Na+]o in mouse skeletal muscle: implications for fatigue
    Simeon P Cairns
    Department of Physiology, School of Medicine, University of Auckland, Auckland 1020, New Zealand
    Am J Physiol Cell Physiol 285:C1131-41. 2003
  4. doi request reprint Changes of surface and t-tubular membrane excitability during fatigue with repeated tetani in isolated mouse fast- and slow-twitch muscle
    Simeon P Cairns
    Institute of Sport and Recreation Research, Auckland 1020, New Zealand
    J Appl Physiol 106:101-12. 2009
  5. pmc Do multiple ionic interactions contribute to skeletal muscle fatigue?
    S P Cairns
    Institute of Sport and Recreation Research New Zealand, Faculty of Health and Environmental Sciences, AUT University, Auckland 1020, New Zealand
    J Physiol 586:4039-54. 2008
  6. doi request reprint Double-sigmoid model for fitting fatigue profiles in mouse fast- and slow-twitch muscle
    S P Cairns
    School of Sport and Recreation, AUT University, Private Bag 92006, Auckland 1020, New Zealand
    Exp Physiol 93:851-62. 2008
  7. ncbi request reprint Stimulation pulse characteristics and electrode configuration determine site of excitation in isolated mammalian skeletal muscle: implications for fatigue
    Simeon P Cairns
    Institute of Sport and Recreation Research New Zealand, Faculty of Health and Environmental Science, Auckland University of Technology, Auckland, New Zealand
    J Appl Physiol 103:359-68. 2007
  8. ncbi request reprint Protective role of extracellular chloride in fatigue of isolated mammalian skeletal muscle
    Simeon P Cairns
    Division of Sport and Recreation, Auckland Univ of Technology, Private Bag 92006, Auckland 1020, New Zealand
    Am J Physiol Cell Physiol 287:C762-70. 2004
  9. doi request reprint Exacerbated potassium-induced paralysis of mouse soleus muscle at 37°C vis-à-vis 25°C: implications for fatigue. K+ -induced paralysis at 37°C
    Simeon P Cairns
    School of Sport and Recreation, Faculty of Health and Environmental Sciences, AUT University, Auckland, New Zealand
    Pflugers Arch 461:469-79. 2011
  10. pmc Logarithmic superposition of force response with rapid length changes in relaxed porcine airway smooth muscle
    G Ijpma
    Institute of Biomedical Technologies, Auckland University of Technology, New Zealand
    Am J Physiol Lung Cell Mol Physiol 299:L898-904. 2010

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Evaluation of models used to study neuromuscular fatigue
    Simeon P Cairns
    Division of Sport and Recreation, Faculty of Health, Auckland University of Technology, Private Bag 92006, Auckland 1020, New Zealand
    Exerc Sport Sci Rev 33:9-16. 2005
    ....
  2. ncbi request reprint Lactic acid and exercise performance : culprit or friend?
    Simeon P Cairns
    Institute of Sport and Recreation Research New Zealand, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland, New Zealand
    Sports Med 36:279-91. 2006
    ..To reconcile the findings from isolated muscle fibres through to whole-body exercise, it is hypothesised that a severe plasma acidosis in humans might impair exercise performance by causing a reduced CNS drive to muscle...
  3. ncbi request reprint Changes of action potentials and force at lowered [Na+]o in mouse skeletal muscle: implications for fatigue
    Simeon P Cairns
    Department of Physiology, School of Medicine, University of Auckland, Auckland 1020, New Zealand
    Am J Physiol Cell Physiol 285:C1131-41. 2003
    ....
  4. doi request reprint Changes of surface and t-tubular membrane excitability during fatigue with repeated tetani in isolated mouse fast- and slow-twitch muscle
    Simeon P Cairns
    Institute of Sport and Recreation Research, Auckland 1020, New Zealand
    J Appl Physiol 106:101-12. 2009
    ..Moreover, mathematical modeling discounts anoxia as the major contributor to fatigue during our stimulation regime in isolated muscles...
  5. pmc Do multiple ionic interactions contribute to skeletal muscle fatigue?
    S P Cairns
    Institute of Sport and Recreation Research New Zealand, Faculty of Health and Environmental Sciences, AUT University, Auckland 1020, New Zealand
    J Physiol 586:4039-54. 2008
    ..We hypothesize that during high-intensity exercise a rundown of the transsarcolemmal K(+) gradient is the dominant cellular process around which interactions with other ions and metabolites occur, thereby contributing to fatigue...
  6. doi request reprint Double-sigmoid model for fitting fatigue profiles in mouse fast- and slow-twitch muscle
    S P Cairns
    School of Sport and Recreation, AUT University, Private Bag 92006, Auckland 1020, New Zealand
    Exp Physiol 93:851-62. 2008
    ..We conclude that a double-sigmoid expression is a useful and accurate model to characterize fatigue in isolated muscle preparations...
  7. ncbi request reprint Stimulation pulse characteristics and electrode configuration determine site of excitation in isolated mammalian skeletal muscle: implications for fatigue
    Simeon P Cairns
    Institute of Sport and Recreation Research New Zealand, Faculty of Health and Environmental Science, Auckland University of Technology, Auckland, New Zealand
    J Appl Physiol 103:359-68. 2007
    ..Using this new understanding, we showed that disrupted propagation of action potentials along the surface membrane is a major cause of fatigue in soleus muscle that is focally and continuously stimulated at 125 Hz...
  8. ncbi request reprint Protective role of extracellular chloride in fatigue of isolated mammalian skeletal muscle
    Simeon P Cairns
    Division of Sport and Recreation, Auckland Univ of Technology, Private Bag 92006, Auckland 1020, New Zealand
    Am J Physiol Cell Physiol 287:C762-70. 2004
    ..This phenomenon possibly involves attenuation of the depolarization caused by stimulation- or exercise-induced run-down of the transsarcolemmal K(+) gradient...
  9. doi request reprint Exacerbated potassium-induced paralysis of mouse soleus muscle at 37°C vis-à-vis 25°C: implications for fatigue. K+ -induced paralysis at 37°C
    Simeon P Cairns
    School of Sport and Recreation, Faculty of Health and Environmental Sciences, AUT University, Auckland, New Zealand
    Pflugers Arch 461:469-79. 2011
    ..Thus, catecholamines are likely to stimulate the Na+ -K+ pump more powerfully at 37°C to restore excitability and attenuate, but not prevent, the detrimental effects of K+...
  10. pmc Logarithmic superposition of force response with rapid length changes in relaxed porcine airway smooth muscle
    G Ijpma
    Institute of Biomedical Technologies, Auckland University of Technology, New Zealand
    Am J Physiol Lung Cell Mol Physiol 299:L898-904. 2010
    ..The similarity in response between relaxed and contracted states implies that the investigated passive dynamics play an important role in both states and should be taken into account...
  11. ncbi request reprint Changes of motor drive, cortical arousal and perceived exertion following prolonged cycling to exhaustion
    Jarrod D Presland
    Division of Sport and Recreation, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland, 1020, New Zealand
    Eur J Appl Physiol 95:42-51. 2005
    ..These data suggest that with prolonged cycling: (1) there is considerable and a persistent form of central fatigue, (2) there is an increased level of cortical arousal, and (3) exhaustion is linked to very high subjective RPE...