Leon J Nesti

Summary

Publications

  1. pmc Mesenchymal stem cell therapy for attenuation of scar formation during wound healing
    Wesley M Jackson
    Clinical and Experimental Orthopaedics Laboratory, Department of SurgeryUniformed Services University, Bethesda, MD 20814, USA
    Stem Cell Res Ther 3:20. 2012
  2. pmc Differentiation potential of multipotent progenitor cells derived from war-traumatized muscle tissue
    Leon J Nesti
    J Bone Joint Surg Am 90:2390-8. 2008
  3. doi request reprint In vitro adipose tissue engineering using an electrospun nanofibrous scaffold
    Rabie M Shanti
    Department of Health and Human Services, Cartilage Biology and Orthopaedics Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA
    Ann Plast Surg 61:566-71. 2008
  4. ncbi request reprint Human marrow-derived mesenchymal progenitor cells: isolation, culture expansion, and analysis of differentiation
    Edward J Caterson
    Cartilage Biology and Orthopedics Branch, National Institute of Arthritis, and Musculoskeletal Skin Diseases, National Institutes of Health, Bethesda, MD 20992 5755, USA
    Mol Biotechnol 20:245-56. 2002
  5. ncbi request reprint TGF-beta1-stimulated osteoblasts require intracellular calcium signaling for enhanced alpha5 integrin expression
    Leon J Nesti
    Department of Orthopaedic Surgery, 501 Curtis Building, Thomas Jefferson University, 1015 Walnut Street, Philadelphia, PA 19107, USA
    Ann N Y Acad Sci 961:178-82. 2002
  6. ncbi request reprint TGF-beta1 calcium signaling increases alpha5 integrin expression in osteoblasts
    Leon J Nesti
    Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
    J Orthop Res 20:1042-9. 2002
  7. ncbi request reprint Titanium particles suppress expression of osteoblastic phenotype in human mesenchymal stem cells
    Mark L Wang
    Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
    J Orthop Res 20:1175-84. 2002
  8. pmc Myeloperoxidase and chlorinated peptides in osteoarthritis: potential biomarkers of the disease
    Marla J Steinbeck
    Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Orthop Res 25:1128-35. 2007
  9. ncbi request reprint Adult mesenchymal stem cells: biological properties, characteristics, and applications in maxillofacial surgery
    Rabie M Shanti
    Cartilage Biology and Orthopaedics Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Oral Maxillofac Surg 65:1640-7. 2007

Collaborators

Detail Information

Publications9

  1. pmc Mesenchymal stem cell therapy for attenuation of scar formation during wound healing
    Wesley M Jackson
    Clinical and Experimental Orthopaedics Laboratory, Department of SurgeryUniformed Services University, Bethesda, MD 20814, USA
    Stem Cell Res Ther 3:20. 2012
    ..This review identifies specific mechanisms by which mesenchymal stem cells can limit tissue fibrosis and summarizes recent in vivo studies where these cells have been used successfully to limit scar formation...
  2. pmc Differentiation potential of multipotent progenitor cells derived from war-traumatized muscle tissue
    Leon J Nesti
    J Bone Joint Surg Am 90:2390-8. 2008
    ..The site of injury is also the site of healing, and we propose that d├ębrided muscle tissue contains cells with robust reparative and regenerative potential...
  3. doi request reprint In vitro adipose tissue engineering using an electrospun nanofibrous scaffold
    Rabie M Shanti
    Department of Health and Human Services, Cartilage Biology and Orthopaedics Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA
    Ann Plast Surg 61:566-71. 2008
    ..These results suggest that the poly L-lactic acid-based nanofibrous scaffold is a promising candidate for adult stem cell-based engineering of adipose tissue...
  4. ncbi request reprint Human marrow-derived mesenchymal progenitor cells: isolation, culture expansion, and analysis of differentiation
    Edward J Caterson
    Cartilage Biology and Orthopedics Branch, National Institute of Arthritis, and Musculoskeletal Skin Diseases, National Institutes of Health, Bethesda, MD 20992 5755, USA
    Mol Biotechnol 20:245-56. 2002
    ....
  5. ncbi request reprint TGF-beta1-stimulated osteoblasts require intracellular calcium signaling for enhanced alpha5 integrin expression
    Leon J Nesti
    Department of Orthopaedic Surgery, 501 Curtis Building, Thomas Jefferson University, 1015 Walnut Street, Philadelphia, PA 19107, USA
    Ann N Y Acad Sci 961:178-82. 2002
    ..These early events are necessary for osteoblast adhesion; thus they determine the fate of the cell and ultimately affect bone function...
  6. ncbi request reprint TGF-beta1 calcium signaling increases alpha5 integrin expression in osteoblasts
    Leon J Nesti
    Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
    J Orthop Res 20:1042-9. 2002
    ..The TGF-beta1 induced intracellular Ca2+ signal in human osteoblasts is thus an important mechanistic step in the regulation of alpha5 integrin expression, later contributing to enhanced cell adhesion...
  7. ncbi request reprint Titanium particles suppress expression of osteoblastic phenotype in human mesenchymal stem cells
    Mark L Wang
    Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA
    J Orthop Res 20:1175-84. 2002
    ..Understanding the nature of hMSC bioreactivity to orthopaedic wear debris should provide additional insights into mechanisms underlying aseptic loosening...
  8. pmc Myeloperoxidase and chlorinated peptides in osteoarthritis: potential biomarkers of the disease
    Marla J Steinbeck
    Department of Orthopaedic Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Orthop Res 25:1128-35. 2007
    ..Patients in the control and advanced OA groups demonstrated little elevation in MPO levels and Cl-peptides were undetectable. These results indicate that MPO and Cl-peptides may serve as diagnostic markers for the detection of early OA...
  9. ncbi request reprint Adult mesenchymal stem cells: biological properties, characteristics, and applications in maxillofacial surgery
    Rabie M Shanti
    Cartilage Biology and Orthopaedics Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Oral Maxillofac Surg 65:1640-7. 2007