K N Naresh

Summary

Publications

  1. ncbi request reprint Angiogenesis is redundant for tumour growth in lymph node metastases
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, 400 012, India
    Histopathology 38:466-70. 2001
  2. ncbi request reprint Regional variation in the distribution of subtypes of lymphoid neoplasms in India
    K N Naresh
    Lymphoma Registry, Tata Memorial Hospital, Parel, Mumbai 400012, India
    Leuk Lymphoma 43:1939-43. 2002
  3. ncbi request reprint Expression of P53 and bcl-2 proteins in T-cell lymphoblastic lymphoma: prognostic implications
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, India
    Leuk Lymphoma 43:333-7. 2002
  4. ncbi request reprint Use of the World Health Organization (WHO) classification of non-Hodgkin's lymphoma in Mumbai, India: a review of 200 consecutive cases by a panel of five expert hematopathologists
    Kikkeri N Naresh
    Lymphoma Registry, Department of Pathology, Tata Memorial Hospital, Mumbai, India
    Leuk Lymphoma 45:1569-77. 2004
  5. ncbi request reprint Do metastatic tumours from an unknown primary reflect angiogenic incompetence of the tumour at the primary site?--a hypothesis
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Mumbai, India
    Med Hypotheses 59:357-60. 2002
  6. ncbi request reprint Apoptosis index is a predictor of metastatic phenotype in patients with early stage squamous carcinoma of the tongue: a hypothesis to support this paradoxical association
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Dr E Borges Marg, Parel, Mumbai 400 012 Bombay, India
    Cancer 91:578-84. 2001
  7. ncbi request reprint Epstein-Barr virus association in classical Hodgkin's disease provides survival advantage to patients and correlates with higher expression of proliferation markers in Reed-Sternberg cells
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Mumbai, India
    Ann Oncol 11:91-6. 2000
  8. ncbi request reprint Distribution of various subtypes of non-Hodgkin's lymphoma in India: a study of 2773 lymphomas using R.E.A.L. and WHO Classifications
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Mumbai, India
    Ann Oncol 11:63-7. 2000
  9. ncbi request reprint Expression of adhesion molecules in B-cell chronic lymphocytic leukaemia: an analysis in lymphoid compartments--peripheral blood, bone marrow and lymph node
    J J Nadkarni
    Immunology Division, Tata Memorial Hospital, Tata Memorial Centre, Mumbai Bombay, India
    Cancer Biother Radiopharm 13:269-74. 1998
  10. ncbi request reprint CD40-ligation-mediated protection from apoptosis of a Fas-sensitive Hodgkin's-disease-derived cell line
    S S Metkar
    Immunology Division, Cancer Research Institute, Tata Memorial Centre, Parel, Mumbai, India
    Cancer Immunol Immunother 47:104-12. 1998

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Angiogenesis is redundant for tumour growth in lymph node metastases
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, 400 012, India
    Histopathology 38:466-70. 2001
    ..As the role of angiogenesis is unclear in the pathogenesis of primary lymph node (LN) tumours, we wondered whether neoangiogenesis was important in supporting and promoting the growth of tumours in LNs...
  2. ncbi request reprint Regional variation in the distribution of subtypes of lymphoid neoplasms in India
    K N Naresh
    Lymphoma Registry, Tata Memorial Hospital, Parel, Mumbai 400012, India
    Leuk Lymphoma 43:1939-43. 2002
    ..5% of NHLs at Barshi, they accounted for 31 and 27.5% of all NHLs at Pondicherry and Jaipur, respectively. There were also notable differences in the specific subtypes of NHL between the three different geographic regions in India...
  3. ncbi request reprint Expression of P53 and bcl-2 proteins in T-cell lymphoblastic lymphoma: prognostic implications
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, India
    Leuk Lymphoma 43:333-7. 2002
    ..T-LL pts negative for p53 are likely to benefit from the short intense protocol--MCL-842. Bcl-2 protein overexpression was not a prognostic factor in these patients...
  4. ncbi request reprint Use of the World Health Organization (WHO) classification of non-Hodgkin's lymphoma in Mumbai, India: a review of 200 consecutive cases by a panel of five expert hematopathologists
    Kikkeri N Naresh
    Lymphoma Registry, Department of Pathology, Tata Memorial Hospital, Mumbai, India
    Leuk Lymphoma 45:1569-77. 2004
    ..This suggests that the distribution of the B-cell and T-cell lymphomas in the Indian population, except for lymphoblastic lymphoma, lies in between the Western world (mainly Caucasian) and the Orientals...
  5. ncbi request reprint Do metastatic tumours from an unknown primary reflect angiogenic incompetence of the tumour at the primary site?--a hypothesis
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Mumbai, India
    Med Hypotheses 59:357-60. 2002
    ..Contrary to this, tumour cells reaching lymph nodes (LN) grow without acquiring any phenotypic or genotypic change, as angiogenesis is redundant for growth within the metastatic LNs...
  6. ncbi request reprint Apoptosis index is a predictor of metastatic phenotype in patients with early stage squamous carcinoma of the tongue: a hypothesis to support this paradoxical association
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Dr E Borges Marg, Parel, Mumbai 400 012 Bombay, India
    Cancer 91:578-84. 2001
    ..The authors investigated the clinical relevance of the apoptotic index (AI), the proliferation index, and tumor grade in relation to LN metastasis in patients with early stage squamous carcinoma of the oral tongue...
  7. ncbi request reprint Epstein-Barr virus association in classical Hodgkin's disease provides survival advantage to patients and correlates with higher expression of proliferation markers in Reed-Sternberg cells
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Mumbai, India
    Ann Oncol 11:91-6. 2000
    ..Hence, we investigated whether cHD with and without EBV-association differ with respect to the proliferation index of the RS cells. Further we investigated whether this would have a bearing on patients survival...
  8. ncbi request reprint Distribution of various subtypes of non-Hodgkin's lymphoma in India: a study of 2773 lymphomas using R.E.A.L. and WHO Classifications
    K N Naresh
    Department of Pathology, Tata Memorial Hospital, Mumbai, India
    Ann Oncol 11:63-7. 2000
    ..This is the first study from India that has incorporated immunophenotypic findings while investigating the distribution of NHL subtypes...
  9. ncbi request reprint Expression of adhesion molecules in B-cell chronic lymphocytic leukaemia: an analysis in lymphoid compartments--peripheral blood, bone marrow and lymph node
    J J Nadkarni
    Immunology Division, Tata Memorial Hospital, Tata Memorial Centre, Mumbai Bombay, India
    Cancer Biother Radiopharm 13:269-74. 1998
    ..001). Proliferating cell nuclear antigen expression in LN sections correlated inversely with VLA-4 expression on BM and PB lymphoid cells (p < 0.05). There was no significant correlation between expression of CAMs and bcl-2 protein...
  10. ncbi request reprint CD40-ligation-mediated protection from apoptosis of a Fas-sensitive Hodgkin's-disease-derived cell line
    S S Metkar
    Immunology Division, Cancer Research Institute, Tata Memorial Centre, Parel, Mumbai, India
    Cancer Immunol Immunother 47:104-12. 1998
    ..sCD40L-mediated protection could not be attributed to reduction in surface Fas expression, increase in Bcl-2 levels or to increase in the levels of soluble Fas isoforms...
  11. ncbi request reprint CD40 Ligand--an anti-apoptotic molecule in Hodgkin's disease
    S S Metkar
    Immunology Division, Cancer Research Institute, Tata Memorial Centre, Parel, Mumbai 400 012, India
    Cancer Biother Radiopharm 16:85-92. 2001
    ..We conclude that CD40L can act as an important anti-apoptotic molecule by upregulating BclxL expression in Reed-Sternberg cells of HD and may be partly responsible for their survival 'in-vivo'...
  12. ncbi request reprint Establishment of a human squamous cell carcinoma cell line of the upper aero-digestive tract
    R Mulherkar
    Laboratory of Genetic Engineering, Cancer Research Institute, Tata Memorial Centre, Parel, India
    Cancer Lett 118:115-21. 1997
    ..Characterization of the NT-8e cell line including growth parameters, anchorage-independent growth and tumorigenicity in nude mice, chromosome counts and DNA content by flow cytometry have been carried out...
  13. ncbi request reprint Hodgkin's disease involving Waldeyer's ring: a study of four cases
    G M Moghe
    Department of Pathology, Tata Memorial Hospital, Mumbai, India
    Leuk Lymphoma 41:151-6. 2001
    ..Morphologically, such extranodal lesions, especially in locations like the oropharynx and nasopharynx, should be differentiated from EBV-associated lymphoproliferations...
  14. ncbi request reprint Study of the distribution of 289 non-Hodgkin lymphomas using the WHO classification among children and adolescents in India
    V Srinivas
    Lymphoma Registry, Department of Pathology, Tata Memorial Hospital, Mumbai, India
    Med Pediatr Oncol 39:40-3. 2002
  15. ncbi request reprint Consolidation radiation after complete remission in Hodgkin's disease following six cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy: is there a need?
    S Laskar
    Department of Radiation Oncology, Tata Memorial Hospital, Dr Ernest Borges Marg, Parel 400 012, Mumbai, India
    J Clin Oncol 22:62-8. 2004
    ....
  16. ncbi request reprint Systemic anaplastic large cell lymphoma presenting as a bladder neoplasm
    Sanjay A Pai
    Department of Pathology, Manipal Hospital, Airport Road, Bangalore 560 017, India
    Leuk Lymphoma 45:841-3. 2004
    ..The lymph node biopsy showed similar features on hematoxylin and eosin section. The patient was put on a regime of CHOP and is disease-free 33 months after diagnosis...
  17. ncbi request reprint Demonstration of cytokeratin-5 non-expression in tobacco related oral carcinogenesis--use of reverse transcriptase polymerase chain reaction as a sensitive assay
    S S Sawant
    Biochemistry and Cell Biology, Tata Memorial Centre, Advanced Centre for Treatment Research and Education in Cancer, Plot No 2, Sector 22, Khargar, Navi 410 208, Mumbai, India
    Oral Oncol 39:789-95. 2003
    ..Thus, in conclusion, our results have shown that CK-5 non-expression is the result of transcriptional block. We proposed CK-5 non-expression as a potential marker for the early diagnosis of tobacco related oral cancer...
  18. ncbi request reprint Inhibition of nitrosodiethylamine-induced hepatocarcinogenesis by dietary turmeric in rats
    R Thapliyal
    Carcinogenesis Division, Cancer Research Institute, Tata Memorial Center, Parel, Mumbai 400 012, India
    Toxicol Lett 139:45-54. 2003
    ..On the other hand, similar levels of turmeric treatment (0.2, 1 and 5%) after exposure to NDEA did not show any protective effects. The underlying mechanism(s) of chemoprevention of NDEA-induced hepatocarcinogenesis need to be explored...
  19. ncbi request reprint Metastasis of squamous cell carcinoma of the oral tongue is associated with down-regulation of epidermal fatty acid binding protein (E-FABP)
    Ramanathan S Uma
    Department of Pathology, Tata Memorial Hospital, Dr Ernest Borges Road, Parel, Mumbai 400 012, India
    Oral Oncol 43:27-32. 2007
    ..Its expression was up to 4-fold higher in the primary tumours (67%) as compared to the corresponding metastatic lymph nodes by northern blot analysis...
  20. ncbi request reprint Lymphoid neoplasms in HIV-positive individuals in India
    Beamon Agarwal
    Lymphoma Registry, Department of Pathology, Tata Memorial Hospital, Mumbai, India
    J Acquir Immune Defic Syndr 29:181-3. 2002
    ..A p53 protein overexpression was noted in 6 of 10 IBLs, 1 of 3 BLs, 2 of 3 CBLs, and 5 of 7 cases of HD. This is the first reported study of lymphoid malignancies in HIV-positive individuals from India...
  21. ncbi request reprint Bcl-2 family of proteins in indolent B-cell non-Hodgkin's lymphoma: study of 116 cases
    Beamon Agarwal
    Department of Pathology, Tata Memorial Hospital, Mumbai, Bombay, India
    Am J Hematol 70:278-82. 2002
    ..Expression of bak was moderate/low among most cases of CLL, MZBCL, and MCL but was absent/low among most cases of FL. The different subsets of IB-NHLs differ in their expression of mcl-1, bax, and bak proteins...
  22. doi request reprint Bone marrow trephine morphology and immunohistochemical findings in chronic myelomonocytic leukaemia
    Nye Thane Ngo
    Department of Histopathology, Hammersmith Hospital and Imperial College, London, UK
    Br J Haematol 141:771-81. 2008
    ..Morphological and immunohistochemical features of BMTB samples are extremely helpful in the diagnosis of CMML...
  23. ncbi request reprint Bone marrow trephine findings in acute myeloid leukaemia with multilineage dysplasia
    Nyethane Ngo
    Department of Histopathology, Hammersmith Hospital and Imperial College, London, UK
    Br J Haematol 140:279-86. 2008
    ..This has to be seen not just in light of its utility at diagnosis, but also the role the diagnostic BMTB would play for purposes of comparison when follow-up BMTBs are submitted in this group of patients...
  24. ncbi request reprint Aberrant positivity for CD79a in erythroid lineage cells--a finding observed in a subset of re-staging bone marrow trephine biopsies after treatment cell pain
    Rashpal Singh Flora
    Haematologica 92:855-6. 2007
    ..It is important to appreciate this finding especially in rituximab treated patients where one tends to rely on CD79a to identify minimal marrow disease...
  25. ncbi request reprint MUM1 expression dichotomises follicular lymphoma into predominantly, MUM1-negative low-grade and MUM1-positive high-grade subtypes
    Kikkeri N Naresh
    Haematologica 92:267-8. 2007
    ..The analysis suggests that MUM1 expression dichotomises FL into low-grade FL of CD10+/Bcl-6+/MUM1-/Ki-67low phenotype, and high-grade FL of CD10+/- /Bcl-6+/weak/MUM1+/ Ki-67high phenotype...
  26. ncbi request reprint Expression of enhancing factor/phospholipase A2 in skin results in abnormal epidermis and increased sensitivity to chemical carcinogenesis
    Rita Mulherkar
    Cancer Research Institute, Advanced Centre for Treatment, Research and Education in Cancer, Kharghar, Navi Mumbai, India
    Oncogene 22:1936-44. 2003
    ..The conversion rate of papilloma to carcinoma was two fold higher in the transgenic mice...
  27. ncbi request reprint Re: Doussis-Anagnostopoulou et al. Vascular endothelial growth factor (VEGF) is expressed by neoplastic Hodgkin-Reed-Sternberg cells in Hodgkin's disease. J Pathol 2002; 197: 677-683
    Beamon Agarwal
    J Pathol 201:334-5. 2003
  28. doi request reprint Lymph nodes involved by multicentric Castleman disease among HIV-positive individuals are often involved by Kaposi sarcoma
    Kikkeri N Naresh
    Department of Histopathology, Hammersmith Hospital and Imperial College, London, UK
    Am J Surg Pathol 32:1006-12. 2008
    ....