Chang I, Lim H, Kim K, Shin H, Namgung U. Enhanced axonal regeneration of the injured sciatic nerve by administration of Buyang Huanwu decoction. J Ethnopharmacol. 2016;194:626-634 pubmed publisher
..Our results suggest that BYHWD administration into animals given sciatic nerve injury facilitates axonal regeneration by acting on both the axons undergoing regeneration and neighboring Schwann cells and improves functional recovery. ..
Shin H, Park J, Lim H, Namgung U. Induction of ?6 and ?1 integrins by acupuncture stimulation in rats. Biochem Biophys Res Commun. 2017;491:629-635 pubmed publisher
Kim K, Namgung U. Facilitating effects of Buyang Huanwu decoction on axonal regeneration after peripheral nerve transection. J Ethnopharmacol. 2018;213:56-64 pubmed publisher
..Our data suggest that BYHWD treatment may contribute to the timely interaction between regenerating axons and distal Schwann cells in the transected nerve and facilitate axonal regeneration. ..
Chang I, Kim K, Namgung U. Î±6 and Î²1 Integrin Heterodimer Mediates Schwann Cell Interactions with Axons and Facilitates Axonal Regeneration after Peripheral Nerve Injury. Neuroscience. 2018;371:49-59 pubmed publisher
..The present data suggest that Î±6 and Î²1 integrins induced in Schwann cells after nerve injury may play a role in mediating Schwann cell interactions with axons and promote axonal regeneration. ..
Shin H, Lee J, Kim K, Shin H, Choi J, Lee C, et al
. Modulation of hippocampal neuronal activity by So-ochim-tang-gamibang in mice subjected to chronic restraint stress. BMC Complement Altern Med. 2017;17:456 pubmed publisher
..Our data suggest that SOCG treatment may increase synaptic responsiveness to serotonergic neuronal inputs by upregulating 5-HT1AR in the hippocampal neurons. ..